Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Santiago (72% of total searches to Chile). The next most popular destinations are Puerto Natales (11%) and Torres del Paine (9%). Searches for hotels in San Pedro de Atacama (8%) are also popular.
Based on KAYAK hotel searches, the most popular region to stay in Chile is Region Metropolitana. Magallanes and Valparaíso are also very popular.
KAYAK users have found double rooms in Chile for as cheap as $12 (Santiago) in the last 3 days. The average price is $116.