The Quality Inn hotel in Seneca, SC is a great destination for all travelers to the Seneca area. Just a fifteen-minute drive from Clemson University, the hotel is perfectly located so our guests can take advantage of the great business and leisure options in Seneca. It is also close to two different lakes as well as the scenic Blue Ridge Mountains. Ram Cat Alley is held each year in historic downtown Seneca as is OctoberFest. Pet Accommodation: 20.00 USD Per Night and Per Pet. Pet limit: A maximum of 25 pounds, and 2 pets per room.