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Find Flight Deals from San Francisco to Des Moines (SFO - DSM)

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from San Francisco to Des Moines

(Round-trip)
Depart: Tue May 12 2015 Return: Wed May 13 2015 Trip spans 2 days
American Airlines
American Airlines
SFO
7:59p
DSM
2:58a
6h 59m
1 stop
DSM
5:50a
SFO
1:37p
7h 47m
1 stop
Depart: Wed Apr 15 2015 Return: Fri Apr 17 2015 Trip spans 3 days
Multiple Airlines
Multiple Airlines
SFO
2:00a
DSM
6:35a
4h 35m
1 stop
DSM
10:49a
SFO
5:48p
6h 59m
1 stop
Depart: Mon Apr 13 2015 Return: Fri Apr 17 2015 Trip spans 5 days
Delta
Delta
SFO
8:25p
DSM
4:29a
8h 04m
1 stop
DSM
10:49a
SFO
5:48p
6h 59m
1 stop
Depart: Tue Apr 14 2015 Return: Fri Apr 17 2015 Trip spans 4 days
Delta
Delta
SFO
2:30a
DSM
8:14a
5h 44m
1 stop
DSM
10:49a
SFO
5:48p
6h 59m
1 stop
Depart: Thu Apr 16 2015 Return: Fri Apr 17 2015 Trip spans 2 days
American Airlines
American Airlines
SFO
2:00a
DSM
8:32a
6h 32m
1 stop
DSM
2:42p
SFO
9:59p
7h 17m
1 stop
Depart: Fri Apr 17 2015 Return: Sat Apr 18 2015 Trip spans 2 days
Delta
Delta
SFO
8:25p
DSM
4:32a
8h 07m
1 stop
DSM
12:15p
SFO
7:45p
7h 30m
1 stop
Depart: Sat Apr 18 2015 Return: Mon Apr 20 2015 Trip spans 3 days
Delta
Delta
SFO
4:00a
DSM
9:24a
5h 24m
1 stop
DSM
10:49a
SFO
5:48p
6h 59m
1 stop
Depart: Mon Apr 20 2015 Return: Fri Apr 24 2015 Trip spans 5 days
American Airlines
American Airlines
SFO
8:55p
DSM
2:52a
5h 57m
1 stop
DSM
2:42p
SFO
9:59p
7h 17m
1 stop
Depart: Tue Apr 21 2015 Return: Fri Apr 24 2015 Trip spans 4 days
American Airlines
American Airlines
SFO
2:00a
DSM
8:32a
6h 32m
1 stop
DSM
2:42p
SFO
9:59p
7h 17m
1 stop
Depart: Fri May 1 2015 Return: Fri May 8 2015 Trip spans 8 days
Delta
Delta
SFO
4:10a
DSM
10:37a
6h 27m
1 stop
DSM
12:15p
SFO
8:16p
8h 01m
1 stop
Depart: Sun May 3 2015 Return: Tue May 12 2015 Trip spans 10 days
Delta
Delta
SFO
8:30p
DSM
4:29a
7h 59m
1 stop
DSM
11:26a
SFO
7:59p
8h 33m
1 stop
Depart: Mon May 4 2015 Return: Tue May 12 2015 Trip spans 9 days
Delta
Delta
SFO
2:25a
DSM
8:51a
6h 26m
1 stop
DSM
3:20a
SFO
9:25a
6h 05m
1 stop
Depart: Tue May 5 2015 Return: Tue May 12 2015 Trip spans 8 days
American Airlines
American Airlines
SFO
11:50a
DSM
5:30p
5h 40m
1 stop
DSM
2:40a
SFO
11:12a
8h 32m
1 stop
Depart: Sun May 10 2015 Return: Sat May 16 2015 Trip spans 7 days
American Airlines
American Airlines
SFO
8:55p
DSM
2:52a
5h 57m
1 stop
DSM
11:29a
SFO
7:01p
7h 32m
1 stop
Depart: Mon May 11 2015 Return: Wed May 13 2015 Trip spans 3 days
American Airlines
American Airlines
SFO
8:50p
DSM
3:07a
6h 17m
1 stop
DSM
2:45p
SFO
9:45p
7h 00m
1 stop
Depart: Wed May 13 2015 Return: Sat May 16 2015 Trip spans 4 days
American Airlines
American Airlines
SFO
4:35a
DSM
11:48a
7h 13m
1 stop
DSM
11:29a
SFO
8:23p
8h 54m
1 stop
Depart: Fri May 8 2015 Return: Mon May 11 2015 Trip spans 4 days
Multiple Airlines
Multiple Airlines
SFO
2:00a
DSM
11:10a
9h 10m
1 stop
DSM
4:03p
SFO
9:59p
5h 56m
1 stop
Depart: Wed May 20 2015 Return: Wed Jun 10 2015 Trip spans 22 days
Frontier
Frontier
SFO
2:00a
DSM
11:10a
9h 10m
1 stop
DSM
1:55p
SFO
7:34p
5h 39m
1 stop
Depart: Fri Apr 24 2015 Return: Sun Apr 26 2015 Trip spans 3 days
United
United
SFO
8:50a
DSM
4:29p
7h 39m
1 stop
DSM
2:18a
SFO
7:53a
5h 35m
1 stop
Depart: Thu Jun 11 2015 Return: Tue Jun 30 2015 Trip spans 20 days
US Airways
US Airways
SFO
8:01a
DSM
1:49p
5h 48m
1 stop
DSM
4:20p
SFO
10:51p
6h 31m
1 stop
Change your search
Airports
Origin

San Francisco
$299
Destination

Des Moines
$299