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Find Flight Deals from San Francisco to Des Moines (SFO - DSM)

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from San Francisco to Des Moines

(Round-trip)
Depart: Tue Mar 3 2015 Return: Wed Mar 4 2015 Trip spans 2 days
United
United
SFO
5:30p
DSM
5:51a
12h 21m
2 stops
DSM
2:32p
SFO
9:08p
6h 36m
1 stop
Depart: Thu Apr 30 2015 Return: Tue May 5 2015 Trip spans 6 days
Frontier
Frontier
SFO
4:45a
DSM
10:40a
5h 55m
1 stop
DSM
1:10p
SFO
8:59p
7h 49m
1 stop
Depart: Mon May 4 2015 Return: Fri May 8 2015 Trip spans 5 days
Frontier
Frontier
SFO
4:45a
DSM
10:40a
5h 55m
1 stop
DSM
1:10p
SFO
8:59p
7h 49m
1 stop
Depart: Thu May 14 2015 Return: Tue May 19 2015 Trip spans 6 days
Frontier
Frontier
SFO
4:45a
DSM
10:40a
5h 55m
1 stop
DSM
1:10p
SFO
8:59p
7h 49m
1 stop
Depart: Fri Feb 13 2015 Return: Tue Feb 17 2015 Trip spans 5 days
Delta
Delta
SFO
7:30p
DSM
3:38a
8h 08m
1 stop
DSM
2:15a
SFO
10:57a
8h 42m
1 stop
Depart: Thu Feb 19 2015 Return: Sat Feb 28 2015 Trip spans 10 days
American Airlines
American Airlines
SFO
3:21a
DSM
10:30a
7h 09m
1 stop
DSM
12:18p
SFO
8:22p
8h 04m
1 stop
Depart: Tue Feb 17 2015 Return: Fri Feb 20 2015 Trip spans 4 days
Delta
Delta
SFO
7:30p
DSM
3:35a
8h 05m
1 stop
DSM
12:15p
SFO
8:58p
8h 43m
1 stop
Depart: Wed Feb 18 2015 Return: Fri Feb 20 2015 Trip spans 3 days
Delta
Delta
SFO
5:43p
DSM
4:22a
10h 39m
1 stop
DSM
12:15p
SFO
8:58p
8h 43m
1 stop
Depart: Fri Feb 20 2015 Return: Mon Feb 23 2015 Trip spans 4 days
Delta
Delta
SFO
7:30p
DSM
3:33a
8h 03m
1 stop
DSM
10:05a
SFO
5:02p
6h 57m
1 stop
Depart: Thu Feb 26 2015 Return: Mon Mar 2 2015 Trip spans 5 days
American Airlines
American Airlines
SFO
7:30p
DSM
1:47a
6h 17m
1 stop
DSM
12:18p
SFO
8:22p
8h 04m
1 stop
Depart: Fri Feb 27 2015 Return: Mon Mar 2 2015 Trip spans 4 days
American Airlines
American Airlines
SFO
6:30p
DSM
2:38a
8h 08m
1 stop
DSM
8:30a
SFO
6:00p
9h 30m
1 stop
Depart: Mon Mar 2 2015 Return: Wed Mar 4 2015 Trip spans 3 days
American Airlines
American Airlines
SFO
7:30p
DSM
4:10a
8h 40m
1 stop
DSM
12:18p
SFO
8:22p
8h 04m
1 stop
Depart: Fri May 8 2015 Return: Mon May 11 2015 Trip spans 4 days
Frontier
Frontier
SFO
4:45a
DSM
10:40a
5h 55m
1 stop
DSM
1:10p
SFO
8:59p
7h 49m
1 stop
Depart: Sat Feb 21 2015 Return: Mon Feb 23 2015 Trip spans 3 days
American Airlines
American Airlines
SFO
3:21a
DSM
10:30a
7h 09m
1 stop
DSM
12:18p
SFO
8:22p
8h 04m
1 stop
Depart: Mon Feb 16 2015 Return: Thu Mar 19 2015 Trip spans 31 days
Delta
Delta
SFO
7:30p
DSM
3:35a
8h 05m
1 stop
DSM
7:09a
SFO
6:28p
11h 19m
2 stops
Depart: Thu Mar 12 2015 Return: Thu Mar 19 2015 Trip spans 8 days
Delta
Delta
SFO
8:15p
DSM
4:34a
8h 19m
1 stop
DSM
7:09a
SFO
6:28p
11h 19m
2 stops
Depart: Sat Jun 13 2015 Return: Wed Jun 17 2015 Trip spans 5 days
Frontier
Frontier
SFO
4:45a
DSM
12:40p
7h 55m
1 stop
DSM
1:10p
SFO
8:59p
7h 49m
1 stop
Depart: Sun Feb 15 2015 Return: Tue Feb 17 2015 Trip spans 3 days
American Airlines
American Airlines
SFO
7:30p
DSM
1:47a
6h 17m
1 stop
DSM
12:46a
SFO
8:23a
7h 37m
1 stop
Depart: Thu Apr 9 2015 Return: Mon Apr 13 2015 Trip spans 5 days
US Airways
US Airways
SFO
2:00a
DSM
5:30p
15h 30m
1 stop
DSM
2:00p
SFO
8:22p
6h 22m
1 stop
Depart: Mon Jan 26 2015 Return: Wed Jan 28 2015 Trip spans 3 days
Multiple Airlines
Multiple Airlines
SFO
5:35p
DSM
8:14a
14h 39m
2 stops
DSM
6:46a
SFO
11:43a
4h 57m
1 stop
Change your search
Airports
Origin

San Francisco
$339
Destination

Des Moines
$339