Find flights
Deals
When to book
FAQs & Tips
Airlines

Find cheap flights from San Francisco to South America from $142

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from San Francisco to South America departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Fri 5/24
Fri 5/31

Search hundreds of travel sites at once for deals on flights to South America

In the last 7 days travelers have searched 44,632,927 times on KAYAK, and here is why:

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Best South America Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima2 stops$497
Bogotá
Bogotá1 stop$323
Buenos Aires
Buenos Aires2 stops$781
Medellín
Medellín2 stops$356
Sao Paulo
Sao Paulo1 stop$596
Cartagena
Cartagena1 stop$379
Santiago
Santiago2 stops$534
Rio de Janeiro
Rio de Janeiro2 stops$712
Quito
Quito2 stops$438
Guayaquil
Guayaquil1 stop$340
Cali
Cali1 stop$469
Cusco
Cusco2 stops$733
Pereira
Pereira2 stops$406
Barranquilla
Barranquilla2 stops$489
Montevideo
Montevideo2 stops$755
Caracas
Caracas2 stops$1,046
Santa Marta
Santa Marta2 stops$453

Good to know

Low season

August

High season

December

Cheapest flight

$142
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 36% increase in price.
Flight from San Francisco to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from San Francisco to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from San Francisco to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from San Francisco to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to South America from San Francisco is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from San Francisco to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to South America with an airline and back to San Francisco with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from San Francisco to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to South America from San Francisco up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • Morning departure is around 5% more expensive than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from San Francisco to South America

 
Need help choosing which airline to fly with from San Francisco to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 11004 reviews
7.9comfort
8.0entertainment
7.5food
8.2boarding
8.6crew
Airline reviews

There was a loud squeaky sound the whole time we were flying.

6.0 GoodEliza, Apr 2024SAN - LAX
Read more about Delta reviews

There was a loud squeaky sound the whole time we were flying.

I didn’t not like that I could not select my seat and ended up with the worse seat.

The landing was bad and the hostess came two times and i was sleeping but when she served the person that nexts to me I woke up and she didn’t even asked me if I need any drink or snacks two times!!!!

Plane was late because of a mechanical malfunction and the food listed as available was not. Flight attendants seem over worked and under paid. They just done seem happy. And that can be seen in their faces.

Waited 3 hours on a plane to de-ice due to manpower issues. Waited another hour and a half once we landed because of a gate issue. Missed my connections. Created. A total of 13 hours of delay.

Great, on time departure, friendly and accommodating crew, great leg room, Smith flight

Plane was turned around due to fog half way into the flight, Delta did not properly direct passengers to stay on same flight and instead failed to properly rebook on Alaska

Honestly, I didn’t expect that I will experience this long time wait during the check in. There was only one person who was taking care of the passengers for the economy class and it took us to wait about one hour to do our check i. As a result we barely get to the airplane as the gate was at the end of the airport. That is totally not professional where one crue is working at the registration desk with economy and 3-4 crues are helping for the business class.

Like most domestic flights in the US, you are basically on your own with this airline when it comes to food, so be sure to purchase meals and drinks ahead of time or expect to arrive starving and dehydrated (like I was).

You need to be a hacker to get the (Free) WiFi

Copa performed as expected for the amount of money I was willing to spend for the flight; it wasn’t exceptional but it was not bad in any way either. The crew was good; friendly and straightforward. The food was airplane food, so no expectations there and the entertainment was lacking but that was my fault for owning an IPhone with a charging port that’s not compatible with the rest of the world. I’d fly Copa again.

Left my bags in origin city on a business class ticket , spent about 2-3 days in the same clothes plus the flight .

the planes are not modern there are no phone chargers

As usual, the flight with normal legroom was not very comfortable, but the second flight was much better because we had paid for extra legroom. It was very nice to check our bags without an extra fee.

LOCKED MY BAG WITHOUT CONSENT. Had to have my zippers cut upon arrival in Costa Rica.

Pros: "The seats in economy were confortable. The best thing was Copa gave us seats in the second line and my family traveled together."
Cons: "Coffe service could better the experience"
Pros: "The crew was very interested on help and attentive with the passengers. But the seat wasn't comfortable. The design of the cushion is not the best to be seating"
Pros: "You were on time, that is the most important thing in a fly"
Cons: "You could improve your entertainment, you are not a cheap company"
Pros: "That there was seltzer"
Cons: "The management of preparing the flight and plane so that it was ready for the trip!!"
Pros: "Copa was convenient and easy. Very easy boarding process and I appreciated the day flight."
Cons: "This is a business class that is equivalent to a US carrier domestic first class. Good seats, not lay flat but wide on my 737-800. The food and service emulated say American Airlines Domestic 1C as well. Everything was just good enough, and much cheaper that international business on the majors."

They offered food. The crew passed by again offering water. I enjoyed the two seating section. I think is very comfortable instead of the three seat way, unless you seat in the middle; which it's not bad, but I wouldn't prefer. All and all, I think the lay out of the seating rows are better than other airlines so far( I haven't tried many anyways). The lay out makes the getting in and out to use the restroom less uncomfortable and cramped. First time flying with Latam. I will fly with them again

Everything was as you would expect in coach - fine. Flight was close to on time.

I missed my plane because there was a lot of people during the migration process. The airline has the chance to care for their clients and they could get the passengers missing in the flight. I lost a day of work and Montfort transportation to go back home and go to the airport again. Unfortunately the airline doesn’t care about that. I use latam at least 4 times a year, so I guess I need to be treat better. In addition, one on my baggages didyarricw to my destination. So frustrated with this trip.

No air in the middle rows. Had a hard time breathing. Was dying of heat.

Not very good, they nickel & dime you for better seats & pay extra for the checking in bag, bad service all the way around

Horrific checkin procedure with neither Delta nor Latam figuring out how to check me in. 4 hrs on customer support with both and both airlines pointing to each other who should do checking. I was not checked in until morning of flight, which for international flight is concerning.

It was a good experience, the flight was a little too long & the food was ok

Awful, horrible customer service. Flight got delayed and had to spend y the night in Bogota as a result. Very poor

Liked check in process To improve: food and beverages. Not second round was offered and meal had no salad.

the flight from Boston to Curitiba was on time actually 30 minutes earlier. latam was not able to unload the luggage for custom checkup in Sao Paulo ii took two and half hours . i missed the flight to Curitiba spend the night in hotel and then flying in the morning to Curitiba

Hated every minute of it. This flight should have only taken 1.5hrs but was delayed over 10hours. Now I am being told I cannot be compensated or refunded my ticket price or extra leg room, which I purchased but did not receive, because the airline is throwing the blame on the 3rd party I purchased tickets through and 3rd party putting the blame on airline. No one wants to help. They received their money and that's all they care about. Im going on 3 days of still trying to get to my final destination, had to cancel car rental, car insurance and hotel. Currently staying in airport until hotels open up. Thank you Lufthansa, Kayak, Underpricer and United for making this trip the worst ever.

Crew was great and did their best to make us comfortable and captain came out at the beginning to announce why the flight was delayed, weather situation up ahead, and kept us updated throughout the flight.

United WiFi is consistently unusable (it can take 10 mins to load a single web page). If you need Wifi to do work, be prepared to lose half a day of productivity.

Awful. I got stuck next to a person carrying a dog and behind someone with a dog. People need to board these dogs downstairs. The cabin is crowded enough with your pets

Packed in like sardines, very uncomfortable. Sitting the aisle my shoulder was rammed into numerous times by rushing flight attendants. Also flight was very cold.

Beverage and food services are excellent. We enjoy paying the extra for economy plus for the 3 inches more leg room to be exact.

Flight was delayed by 3 hours. The pilot made up 1 hour during the flight, but that made the wait at the airport 5 hours once you factor getting there 2 hours early.

Airline did not explain reasons why flight was delayed two hours. Explanations were badly needed and rarely provided. Problem seemed to clearly be the airline’s fault and not the fault of the weather or airport.

Very uncomfortable seats and seat backs, and I am only 5’9”. Delayed due to crew issues, spent a long time with no ventilation. Teeny overhead bins. Wifi worked well. Arrived safely.

I was delighted that we were able to get on the 4:40 pm flight rather than our original booking at 6:55 pm!! Other than that, the flight was comfortable and landed early😊

The experience was great and much better than the flight going out. of course I was in first class but the service was excellent

Comfort of seats, ease of boarding. Food selection could be better

Food options were limited which is absolutely embarrassing for a Flight of this size The staff did not come around as much and I am not accustomed to such poor service from American Airlines Drinks I believe were limited to soda and water

Crew were attentive and friendly. Flight was smooth and early! I enjoyed the less crowded plane. Thank you!

We are gluten free, there were not any available complimentary gluten free options.

No meal on a cross country flight? SFO-MiA is pretty much the definition of a coast to coast flight. No meal provided. Sky high wi-fi rates too. Stop nickel and diming your customers.

The staff was unprofessional and didn’t communicate very well. The boarding process was very disheveled, potentially due to a power outage the previous day but there was no contingency plan to properly get passengers boarded the following day. Once boarded the aircraft stayed on the tarmac for over 45 minutes due to high winds. The communication was sporadic but an announcement was finally made an additional 30 minutes later that the flight was cancelled but we couldn’t get off the plane. Prior to deplaning one of the gate agents came on the plane and made an announcement for everyone to pickup their checked bags and take a card to rebook a new reservation because they didn’t have adequate staff. Flights were missed, passengers went to different airports and there was little to no assistance from AA.

You cancelled my flight by email then made it very difficult to get in contact with you. Then put me in a flight with a long layover in Mexico returning to the wrong airport in uk. Mind blowing my stressful. I missed see my grand dad because of you.

Apart from the delay due to unforeseen circumstances. The leg from sjc to dfw was fine. It was the leg from dfw to orf that we encountered issues mainly due to the flight attendant crew not being friendly. We had two small children and we needed some assistance to warm up milk so the baby would sleep. The crew just didn’t get it and made things very difficult. One made a remark that the baby’s dirty diaper smell was a “gift” to the plane in a rude way. Normally I’d brush that off as a funny comment if the rest of the trip the attendants were helpful or understanding of the difficulty we faced. But that wasn’t the case. We were met with rudeness on the second leg. Whereas on the first leg the crew were so nice and helpful.

This was not the BA business class it used to be. Mediocre food, attendants seemed stretched thin. All the little luxuries that used to make BA business fun were missing. Flight delayed and the explanation given was they forgot to pick up crew - I hope I misheard! Transfer in LHR “sticky” - we thought we had way too much time at 3hours but it was needed. Next time will try different route.

Book cheap flights from San Francisco to South America

Recent round-trip flight deals

8/16Fri
1 stopAvianca
11h 20mSFO-BOG
8/26Mon
1 stopAvianca
10h 46mBOG-SFO
$323
6/20Thu
1 stopAvianca
9h 45mSFO-BOG
6/25Tue
1 stopAvianca
13h 00mBOG-SFO
$324
5/3Fri
1 stopCopa Airlines
20h 38mSFO-BOG
5/8Wed
1 stopCopa Airlines
14h 01mBOG-SFO
$333
9/10Tue
2 stopsAmerican Airlines
14h 05mSFO-BOG
10/1Tue
1 stopAmerican Airlines
17h 36mBOG-SFO
$338
5/3Fri
1 stopCopa Airlines
16h 39mSFO-BOG
5/8Wed
1 stopCopa Airlines
14h 01mBOG-SFO
$339
5/4Sat
2 stopsAmerican Airlines
16h 36mSFO-BOG
5/8Wed
1 stopAmerican Airlines
18h 24mBOG-SFO
$340
5/3Fri
1 stopDelta
12h 45mSFO-BOG
5/8Wed
2 stopsDelta
18h 26mBOG-SFO
$394
5/5Sun
2 stopsLATAM Airlines
25h 45mSFO-BOG
5/9Thu
2 stopsLATAM Airlines
23h 25mBOG-SFO
$397
8/4Sun
1 stopDelta
26h 04mSFO-BOG
8/12Mon
2 stopsDelta
18h 33mBOG-SFO
$399
5/8Wed
1 stopLATAM Airlines
18h 00mSFO-BOG
5/16Thu
2 stopsLATAM Airlines
19h 22mBOG-SFO
$412

Search by stops

Search by airline

Search by price

Recent one-way flight deals

5/1Wed
1 stopAvianca
9h 45mSFO-BOG
$142
6/10Mon
1 stopAvianca
9h 45mSFO-BOG
$143
4/28Sun
2 stopsAmerican Airlines
15h 20mSFO-BOG
$144
4/28Sun
2 stopsAmerican Airlines
15h 20mSFO-BOG
$148
5/1Wed
1 stopCopa Airlines
13h 40mSFO-BOG
$158
4/28Sun
1 stopCopa Airlines
19h 27mSFO-CTG
$168
6/12Wed
1 stopDelta
20h 21mSFO-BOG
$172
5/25Sat
2 stopsLATAM Airlines
20h 47mSFO-BOG
$178
8/2Fri
1 stopDelta
26h 04mSFO-BOG
$183
7/10Wed
1 stopLATAM Airlines
20h 10mSFO-BOG
$204

Search by stops

Search by airline

Search by price

Last minute flights from San Francisco to South America

Last minute flight, train and bus deals

4/27Sat
multi-stopUnited Airlines
13h 35mSFO-BOG
5/1Wed
multi-stopUnited Airlines
18h 52mBOG-SFO
$335
4/28Sun
multi-stopAmerican Airlines
15h 20mSFO-BOG
5/8Wed
multi-stopAmerican Airlines
18h 24mBOG-SFO
$338
4/26Fri
multi-stopCopa Airlines
13h 39mSFO-BOG
5/7Tue
multi-stopCopa Airlines
14h 01mBOG-SFO
$343
4/25Thu
multi-stopCopa Airlines
13h 39mSFO-BOG
5/3Fri
multi-stopCopa Airlines
10h 55mBOG-SFO
$349
4/25Thu
multi-stopDelta
20h 15mSFO-BOG
5/2Thu
multi-stopDelta
11h 55mBOG-SFO
$389
4/26Fri
multi-stopDelta
11h 45mSFO-BOG
5/8Wed
multi-stopDelta
18h 26mBOG-SFO
$394
4/28Sun
multi-stopAvianca
11h 40mSFO-BOG
5/9Thu
multi-stopAvianca
10h 00mBOG-SFO
$448
4/25Thu
multi-stopAvianca
13h 04mSFO-BOG
5/9Thu
multi-stopAvianca
11h 50mBOG-SFO
$463
4/27Sat
multi-stopLATAM Airlines
13h 05mSFO-LIM
4/29Mon
multi-stopLATAM Airlines
16h 39mLIM-SFO
$483
4/27Sat
multi-stopLATAM Airlines
16h 45mSFO-LIM
4/29Mon
multi-stopLATAM Airlines
18h 30mLIM-SFO
$497

Search by stops

Search by airline

Search by price