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Find Flight Deals from United States to Des Moines

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights to Des Moines

(Round-trip)
Depart: Fri Feb 13 2015 Return: Mon Feb 16 2015 Trip spans 4 days
Frontier
Frontier
DEN
3:34a
DSM
5:06a
1h 32m
nonstop
DSM
6:46a
DEN
8:40a
1h 54m
nonstop
Depart: Thu Jan 8 2015 Return: Sun Jan 11 2015 Trip spans 4 days
Allegiant Air
Allegiant Air
LAS
1:50a
DSM
4:40a
2h 50m
nonstop
DSM
7:35a
LAS
10:43a
3h 08m
nonstop
Depart: Sat Jan 24 2015 Return: Mon Jan 26 2015 Trip spans 3 days
American Airlines
American Airlines
ORD
6:55a
DSM
8:13a
1h 18m
nonstop
DSM
1:09p
ORD
2:35p
1h 26m
nonstop
Depart: Sat Jan 17 2015 Return: Sun Jan 18 2015 Trip spans 2 days
American Airlines
American Airlines
DFW
2:45p
DSM
7:24a
16h 39m
1 stop
DSM
10:24a
DFW
12:25p
2h 01m
nonstop
Depart: Wed Feb 18 2015 Return: Wed Feb 25 2015 Trip spans 8 days
Frontier
Frontier
PHX
1:07a
DSM
5:06a
3h 59m
1 stop
DSM
6:46a
PHX
5:58p
11h 12m
1 stop
Depart: Tue Feb 24 2015 Return: Sat Feb 28 2015 Trip spans 5 days
United
United
MSY
1:47p
DSM
6:20p
4h 33m
1 stop
DSM
10:39a
MSY
5:20p
6h 41m
1 stop
Depart: Sat Jan 10 2015 Return: Tue Jan 13 2015 Trip spans 4 days
US Airways
US Airways
DCA
9:40a
DSM
12:35p
2h 55m
nonstop
DSM
11:45a
DCA
2:02p
2h 17m
nonstop
Depart: Tue Jan 27 2015 Return: Wed Jan 28 2015 Trip spans 2 days
US Airways
US Airways
IAD
2:00a
DSM
9:11a
7h 11m
1 stop
DSM
8:45a
IAD
1:12p
4h 27m
1 stop
Depart: Tue Feb 10 2015 Return: Fri Feb 13 2015 Trip spans 4 days
United
United
IND
3:00a
DSM
9:13a
6h 13m
1 stop
DSM
1:00a
IND
4:22a
3h 22m
1 stop
Depart: Tue Jan 20 2015 Return: Mon Jan 26 2015 Trip spans 7 days
Multiple Airlines
Multiple Airlines
PDX
1:00a
DSM
9:50a
8h 50m
1 stop
DSM
6:46a
PDX
4:14p
9h 28m
1 stop
Depart: Mon Jan 26 2015 Return: Tue Feb 3 2015 Trip spans 9 days
American Airlines
American Airlines
SEA
6:50p
DSM
4:10a
9h 20m
1 stop
DSM
12:31p
SEA
9:18p
8h 47m
1 stop
Depart: Tue Apr 7 2015 Return: Tue Apr 14 2015 Trip spans 8 days
Delta
Delta
SAN
11:00a
DSM
4:58p
5h 58m
1 stop
DSM
3:00a
SAN
11:07a
8h 07m
1 stop
Depart: Mon Feb 9 2015 Return: Tue Feb 17 2015 Trip spans 9 days
Delta
Delta
LAX
7:30p
DSM
3:28a
7h 58m
1 stop
DSM
11:57a
LAX
8:56p
8h 59m
1 stop
Depart: Thu Mar 26 2015 Return: Mon Mar 30 2015 Trip spans 5 days
Delta
Delta
BWI
3:10p
DSM
7:58p
4h 48m
1 stop
DSM
8:00a
BWI
1:15p
5h 15m
1 stop
Depart: Wed May 20 2015 Return: Sat May 30 2015 Trip spans 11 days
Delta
Delta
CLT
10:00a
DSM
7:03p
9h 03m
1 stop
DSM
8:00a
CLT
12:35p
4h 35m
1 stop
Depart: Tue Mar 31 2015 Return: Mon Apr 6 2015 Trip spans 7 days
Frontier
Frontier
SLC
5:10p
DSM
6:07a
12h 57m
1 stop
DSM
7:47a
SLC
11:35a
3h 48m
1 stop
Depart: Tue Mar 3 2015 Return: Sat Mar 7 2015 Trip spans 5 days
United
United
PHL
6:50a
DSM
12:43p
5h 53m
1 stop
DSM
8:54a
PHL
2:31p
5h 37m
1 stop
Depart: Wed May 13 2015 Return: Sun May 17 2015 Trip spans 5 days
United
United
AUS
1:18p
DSM
7:12p
5h 54m
1 stop
DSM
1:40a
AUS
7:21a
5h 41m
1 stop
Depart: Sat May 2 2015 Return: Thu May 7 2015 Trip spans 6 days
Frontier
Frontier
SFO
4:45a
DSM
10:40a
5h 55m
1 stop
DSM
1:10p
SFO
8:59p
7h 49m
1 stop
Depart: Sat May 16 2015 Return: Tue May 19 2015 Trip spans 4 days
American Airlines
American Airlines
MCO
3:40a
DSM
11:37a
7h 57m
1 stop
DSM
3:24a
MCO
8:55a
5h 31m
1 stop
Change your search
Airports
Origin

Charlotte
$285
Portland
$263
Seattle
$264
Chicago
$155
Austin
$303
Washington
only $248
only $237
San Francisco
$313
San Diego
$276
Baltimore
$278
Orlando
$315
New Orleans
$235
Phoenix
$233
Salt Lake City
$293
Los Angeles
$278
Denver
$105
Dallas
$182
Philadelphia
$298
Las Vegas
$139
Indianapolis
$261
Destination

Des Moines
$105