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Find Flight Deals from United States to Des Moines

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights to Des Moines

(Round-trip)
Depart: Fri Mar 13 2015 Return: Wed Mar 18 2015 Trip spans 6 days
Frontier
Frontier
DEN
11:28a
DSM
1:00p
1h 32m
nonstop
DSM
2:40p
DEN
4:27p
1h 47m
nonstop
Depart: Tue Feb 24 2015 Return: Wed Feb 25 2015 Trip spans 2 days
American Airlines
American Airlines
ORD
3:15a
DSM
4:38a
1h 23m
nonstop
DSM
1:09p
ORD
2:34p
1h 25m
nonstop
Depart: Tue Feb 17 2015 Return: Tue Feb 24 2015 Trip spans 8 days
American Airlines
American Airlines
IND
9:30a
DSM
3:00p
5h 30m
1 stop
DSM
8:30a
IND
1:38p
5h 08m
1 stop
Depart: Tue Apr 21 2015 Return: Sun May 3 2015 Trip spans 13 days
United
United
LAS
2:05a
DSM
6:49a
4h 44m
1 stop
DSM
2:24a
LAS
6:53a
4h 29m
1 stop
Depart: Sat May 9 2015 Return: Mon May 11 2015 Trip spans 3 days
American Airlines
American Airlines
BNA
5:26a
DSM
10:37a
5h 11m
1 stop
DSM
3:31p
BNA
7:18p
3h 47m
1 stop
Depart: Tue Apr 7 2015 Return: Mon Apr 13 2015 Trip spans 7 days
US Airways
US Airways
DCA
10:05a
DSM
12:49p
2h 44m
nonstop
DSM
12:40p
DCA
3:07p
2h 27m
nonstop
Depart: Mon Jun 8 2015 Return: Mon Jun 15 2015 Trip spans 8 days
Allegiant Air
Allegiant Air
LAX
4:15a
DSM
7:33a
3h 18m
nonstop
DSM
10:33a
LAX
2:07p
3h 34m
nonstop
Depart: Wed Mar 11 2015 Return: Tue Mar 24 2015 Trip spans 14 days
US Airways
US Airways
EWR
11:00a
DSM
5:03p
6h 03m
1 stop
DSM
2:55a
EWR
7:45a
4h 50m
1 stop
Depart: Thu Mar 19 2015 Return: Mon Mar 23 2015 Trip spans 5 days
Delta
Delta
IAD
2:20a
DSM
7:34a
5h 14m
1 stop
DSM
1:15p
IAD
6:09p
4h 54m
1 stop
Depart: Tue May 12 2015 Return: Tue May 19 2015 Trip spans 8 days
Delta
Delta
PHX
11:55a
DSM
4:58p
5h 03m
1 stop
DSM
2:30a
PHX
11:23a
8h 53m
1 stop
Depart: Thu Jan 29 2015 Return: Wed Feb 4 2015 Trip spans 7 days
American Airlines
American Airlines
CLT
7:55a
DSM
1:41p
5h 46m
1 stop
DSM
6:00a
CLT
12:13p
6h 13m
1 stop
Depart: Sat Mar 28 2015 Return: Sat Apr 4 2015 Trip spans 8 days
Delta
Delta
SNA
2:45a
DSM
10:09a
7h 24m
1 stop
DSM
3:20a
SNA
9:25a
6h 05m
1 stop
Depart: Sat Jun 6 2015 Return: Mon Jun 8 2015 Trip spans 3 days
United
United
DFW
1:20p
DSM
7:16p
5h 56m
1 stop
DSM
3:45p
DFW
9:00p
5h 15m
1 stop
Depart: Wed May 13 2015 Return: Sun May 17 2015 Trip spans 5 days
Delta
Delta
MCO
4:10a
DSM
11:15a
7h 05m
1 stop
DSM
3:00a
MCO
9:30a
6h 30m
1 stop
Depart: Wed Jun 10 2015 Return: Mon Jun 22 2015 Trip spans 13 days
Frontier
Frontier
SLC
6:30a
DSM
11:40a
5h 10m
1 stop
DSM
1:10p
SLC
4:50p
3h 40m
1 stop
Depart: Tue Jun 9 2015 Return: Tue Jun 16 2015 Trip spans 8 days
Multiple Airlines
Multiple Airlines
AUS
8:25a
DSM
12:40p
4h 15m
1 stop
DSM
2:00p
AUS
6:03p
4h 03m
1 stop
Depart: Tue May 19 2015 Return: Tue May 26 2015 Trip spans 8 days
United
United
BOS
2:00a
DSM
7:00a
5h 00m
1 stop
DSM
9:59a
BOS
3:24p
5h 25m
1 stop
Depart: Wed Jul 8 2015 Return: Tue Jul 14 2015 Trip spans 7 days
United
United
PHL
2:30a
DSM
7:00a
4h 30m
1 stop
DSM
2:25p
PHL
6:26p
4h 01m
1 stop
Depart: Tue Jun 23 2015 Return: Tue Jun 30 2015 Trip spans 8 days
United
United
RIC
5:50a
DSM
10:41a
4h 51m
1 stop
DSM
7:05a
RIC
11:25a
4h 20m
1 stop
Depart: Sat Jun 20 2015 Return: Mon Jun 22 2015 Trip spans 3 days
Frontier
Frontier
SFO
4:45a
DSM
12:40p
7h 55m
1 stop
DSM
1:10p
SFO
8:59p
7h 49m
1 stop
Change your search
Airports
Origin

Charlotte
$266
Chicago
$165
Santa Ana
$266
Nashville
$237
Austin
$345
Washington
only $264
only $247
San Francisco
$400
Orlando
$320
Phoenix
$264
Salt Lake City
$326
Los Angeles
$247
Newark
$253
Denver
$105
Dallas
$295
Philadelphia
$354
Las Vegas
$236
Richmond
$386
Boston
$348
Indianapolis
$230
Destination

Des Moines
$105