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Based on KAYAK hotel searches, the most popular destination is Manaus (73% of total searches to Amazon Rainforest). The next most popular destinations are Leticia (17%) and Santarém (6%). Searches for hotels in Rio Branco (4%) are also popular.
KAYAK users have found double rooms in Amazon Rainforest for as cheap as $7 (Leticia) in the last 3 days. The average price is $50.