Paddle or Ski near One of the Best Onalaska Hotels Just five miles from the picturesque Mississippi River and Mt. La Crosse, the Holiday Inn Express® Onalaska (La Crosse Area) hotel is a great home base for water activities. Yet water is not the only thing flowing in Wisconsin. With City Brewery and the world's largest six-pack just a few miles away, this Onalaska hotel's location is pure, distilled fun. This greater La Crosse, WI hotel is less than six miles from the corporate headquarters of Kwik Trip and Trane Company and close to the incredible medical facilities of Mayo Clinic Health Systems and Gundersen Lutheran Hospital. With the 650-sq-ft Valley View room and free high-speed, wireless Internet access, this La Crosse hotel's amenities are everything you'll need to enjoy your stay. The University of Wisconsin - La Crosse is just eight miles from the hotel, putting you moments away from your UWLAX events. You could even hop over to nearby Valley View Mall before cheering along with the university's Colbert the Eagle. Be sure to also plan time for a riverboat cruise down the Mississippi before you leave. With so much to do in La Crosse, WI, hotel visitors will want to charge up with our signature cinnamon rolls from the complimentary, hot Express Start Breakfast Bar in the lobby. Whether you're planning a quick trip or an extended stay, we've got a room for you at the Holiday Inn Express® Onalaska - La Crosse Area hotel.