Find Cheap Flights from Chicago O'Hare International to South America

Depart
Return
1 adult
Adults
18-64
Seniors
65+
Youths
12-17
Children
2-11
Seat Infants
under 2
Lap Infants
under 2
The price shown for each flight will be the average for all passengers including any infants.
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Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights from Chicago O'Hare International to South America

(Round-trip)
Depart: Wed Jan 24 2018 Return: Tue Jan 30 2018 Trip spans 7 days
Spirit Airlines
Spirit Airlines
ORD
CTG
7h 29m
1 stop
CTG
ORD
10h 26m
1 stop
Depart: Wed Jan 17 2018 Return: Wed Jan 24 2018 Trip spans 8 days
Multiple Airlines
Multiple Airlines
ORD
MDE
18h 58m
1 stop
MDE
ORD
8h 44m
1 stop
Depart: Tue Jan 30 2018 Return: Tue Feb 6 2018 Trip spans 8 days
Aeromexico
Aeromexico
ORD
BOG
12h 53m
1 stop
BOG
ORD
23h 02m
1 stop
Depart: Mon Nov 20 2017 Return: Thu Nov 23 2017 Trip spans 4 days
Copa Airlines
Copa Airlines
ORD
BAQ
28h 23m
1 stop
BAQ
ORD
8h 22m
1 stop
Depart: Wed Feb 7 2018 Return: Wed Feb 14 2018 Trip spans 8 days
Avianca
Avianca
ORD
CTG
21h 19m
2 stops
CTG
ORD
17h 03m
3 stops
Depart: Sat Feb 24 2018 Return: Sun Mar 4 2018 Trip spans 9 days
Interjet
Interjet
ORD
LIM
27h 05m
1 stop
LIM
ORD
18h 25m
1 stop
Depart: Tue Jan 30 2018 Return: Wed Feb 7 2018 Trip spans 9 days
Spirit Airlines
Spirit Airlines
ORD
CTG
7h 29m
1 stop
CTG
ORD
10h 26m
1 stop
Depart: Tue Jan 23 2018 Return: Fri Feb 9 2018 Trip spans 18 days
Multiple Airlines
Multiple Airlines
ORD
MDE
18h 58m
1 stop
MDE
ORD
8h 44m
1 stop
Depart: Tue Feb 6 2018 Return: Tue Feb 13 2018 Trip spans 8 days
Spirit Airlines
Spirit Airlines
ORD
MDE
8h 08m
1 stop
MDE
ORD
9h 45m
1 stop
Depart: Tue Mar 6 2018 Return: Mon Mar 12 2018 Trip spans 6 days
Aeromexico
Aeromexico
ORD
BOG
22h 30m
1 stop
BOG
ORD
22h 23m
1 stop
Depart: Mon Nov 20 2017 Return: Tue Nov 28 2017 Trip spans 9 days
Copa Airlines
Copa Airlines
ORD
BAQ
28h 23m
1 stop
BAQ
ORD
21h 14m
1 stop
Depart: Wed Feb 14 2018 Return: Tue Feb 20 2018 Trip spans 7 days
Multiple Airlines
Multiple Airlines
ORD
BOG
48h 25m
2 stops
BOG
ORD
26h 31m
2 stops
Depart: Sun Apr 15 2018 Return: Mon Apr 30 2018 Trip spans 16 days
Avianca
Avianca
ORD
CLO
8h 24m
1 stop
CLO
ORD
18h 11m
2 stops
Depart: Wed Mar 7 2018 Return: Wed Mar 14 2018 Trip spans 7 days
Aeromexico
Aeromexico
ORD
BOG
14h 32m
1 stop
BOG
ORD
15h 58m
1 stop
Depart: Tue Jan 23 2018 Return: Tue Jan 30 2018 Trip spans 8 days
Spirit Airlines
Spirit Airlines
ORD
CTG
18h 19m
1 stop
CTG
ORD
21h 27m
1 stop
Depart: Tue Nov 21 2017 Return: Tue Nov 28 2017 Trip spans 8 days
Copa Airlines
Copa Airlines
ORD
BAQ
14h 19m
1 stop
BAQ
ORD
30h 24m
1 stop
Depart: Sun Apr 8 2018 Return: Sat Apr 14 2018 Trip spans 7 days
Avianca
Avianca
ORD
CTG
21h 13m
2 stops
CTG
ORD
18h 25m
2 stops
Depart: Thu Feb 1 2018 Return: Sat Feb 10 2018 Trip spans 10 days
Aeromexico
Aeromexico
ORD
BOG
14h 32m
1 stop
BOG
ORD
16h 03m
1 stop
Depart: Wed Nov 22 2017 Return: Tue Nov 28 2017 Trip spans 7 days
Copa Airlines
Copa Airlines
ORD
BAQ
22h 43m
1 stop
BAQ
ORD
30h 24m
1 stop
Depart: Thu Jan 18 2018 Return: Wed Jan 24 2018 Trip spans 7 days
Spirit Airlines
Spirit Airlines
ORD
MDE
8h 08m
1 stop
MDE
ORD
9h 45m
1 stop
* Prices are per person and are for e–tickets and include all taxes & fees in USD.

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We’re not the seller.
At KAYAK we don’t set the prices, so it’s not possible for us to guarantee what other companies are selling.

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Our service lets you quickly and easily compare results from hundreds of travel sites at once. In this sense, KAYAK is a search engine and we can't guarantee prices we find.

Why aren’t prices accurate 100% of the time?
Prices on airline seats, hotel rooms and car rentals can change frequently. Several people may also be trying to buy the same travel option simultaneously. As a result, you may find, on occasion, that certain prices are no longer available.

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Airports
Origin

Chicago
$318
Destination

Cali
$398
Lima
$395
Medellin
$335
Cartagena
$318
Bogotá
$350
Barranquilla
$383