Which airports can I use when flying from Des Moines to Syracuse?

Flights from Des Moines to Syracuse usually depart from Des Moines (DSM) and arrive at Syracuse Hancock Intl (SYR).

What cabin classes can I book on flights from Des Moines to Syracuse?

Only Economy Class is available on flights from Des Moines to Syracuse.

Which airports do connecting flights from Des Moines to Syracuse pass through?

One-stop flights from Des Moines to Syracuse most commonly connect through: • Chicago O'Hare Intl (ORD) - 52% of one-stop connections • Detroit Metropolitan Wayne County (DTW) - 34% of one-stop connections • Charlotte Douglas (CLT) - 8% of one-stop connections • Washington, D.C. Reagan-National (DCA) - 5% of one-stop connections Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.

Can I save money by using flexible dates for flights from Des Moines to Syracuse?

On the Des Moines to Syracuse route, being flexible with your departure day can save you up to 42%. Sunday is the cheapest day at $328 round-trip on average, while Monday is the most expensive at $565: a $237 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.

How long is a flight from Des Moines to Syracuse?

A nonstop flight from Des Moines to Syracuse takes 0h 00m, covering 901 miles.

Do I need a passport to fly from Des Moines to Syracuse?

No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.

Have flight prices from Des Moines to Syracuse changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $329 to $1,096. That means the highest observed fare was about 3x higher than the lowest one.

How are flight prices from Des Moines to Syracuse looking right now?

One-way fares from Des Moines to Syracuse are currently higher than usual. Average one-way flight prices are about $478, which is 42% above the typical average for this route.

How much time can I save by choosing a different layover airport from Des Moines to Syracuse?

Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 4h 41m, compared with 5h 04m via Washington, D.C. Reagan-National (DCA) and 5h 16m via Chicago O'Hare Intl (ORD).

What is the time difference between Des Moines and Syracuse?

Syracuse is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

What car rental options are available at Syracuse Hancock Intl Airport (SYR)?

Syracuse Hancock Intl Airport (SYR) hosts 5 major car rental companies, with daily rates starting from around $29 for economy cars. Top options include: • Hertz • Dollar • Budget • Alamo • Avis

How much should I expect to pay for a Des Moines to Syracuse flight?

Round-trip flights from Des Moines to Syracuse range from $343 to $436, with an average of $388 over the past 12 months. Anything below $343 counts as a good deal.

What is the cheapest airline to fly from Des Moines to Syracuse?

Delta ($329) and American Airlines ($334) are the cheapest airlines to fly round-trip from Des Moines to Syracuse according to KAYAK data over the last 5 days.

What is the most popular layover airport when flying from Des Moines to Syracuse?

Chicago O'Hare Intl (ORD) is the most popular layover for the Des Moines to Syracuse route. 52% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via ORD.

What is the cheapest layover airport when flying from Des Moines to Syracuse?

Flights via Philadelphia (PHL) offer the most affordable fares, with an average round-trip price of $300. Based on KAYAK data over the past 3 months.

When flying from Des Moines to Syracuse which airport offers the shortest layover?

Detroit Metropolitan Wayne County (DTW) had the shortest average connection time for Des Moines to Syracuse layovers at 176 minutes over the past 3 months.

$277 CHEAP FLIGHTS from Des Moines to Syracuse (DSM - SYR)

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$329

Typical prices: $343-$436

Delta

Sun 10/21Wed 10/24

DSM - SYR • 1 stop

Cheapest one-way

$306

Typical prices: $294-$378

Multiple Airlines

Fri 11/30

DSM - SYR • 3 stops

Nonstop flights

Not available

There are currently no direct flights between Des Moines and Syracuse. You'll need to take a connecting flight to reach the destination.

Insights

When to travel

October

Cheapest • 30% price drop

December

Most popular

Good to know

Top layover airports

Philadelphia (PHL)

Cheapest • Avg $300 (round-trip)

Detroit Metropolitan Wayne County (DTW)

Shortest trip • 4h 41m (one-way)

Insights

Start a new search

KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to Syracuse!

Flight Deals

Cheap Flights from Des Moines to Syracuse (DSM-SYR)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Des Moines to Syracuse

Wed, Oct 21 - Sat, Oct 24

3:46 pm - 11:29 pmDSM Des Moines-SYR Syracuse Hancock Intl

6h 43m1 stop Minneapolis St Paul

6:22 am - 9:42 amSYR Syracuse Hancock Intl-DSM Des Moines

4h 20m1 stop Detroit Metropolitan Wayne County

$329Delta

Thu, Oct 22 - Sun, Oct 25

5:50 pm - 11:18 pmDSM Des Moines-SYR Syracuse Hancock Intl

4h 28m1 stop Detroit Metropolitan Wayne County

5:20 pm - 8:40 pmSYR Syracuse Hancock Intl-DSM Des Moines

4h 20m1 stop Detroit Metropolitan Wayne County

$329Delta

Fri, Oct 9 - Tue, Oct 13

5:50 pm - 11:18 pmDSM Des Moines-SYR Syracuse Hancock Intl

4h 28m1 stop Detroit Metropolitan Wayne County

12:10 pm - 7:14 pmSYR Syracuse Hancock Intl-DSM Des Moines

8h 04m1 stop New York LaGuardia

$329Delta

Sat, Nov 14 - Sat, Nov 21

9:25 am - 6:06 pmDSM Des Moines-SYR Syracuse Hancock Intl

7h 41m1 stop Chicago O'Hare Intl

5:21 pm - 12:19 amSYR Syracuse Hancock Intl-DSM Des Moines

7h 58m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$334American Airlines

Wed, Oct 21 - Sat, Oct 24

2:01 pm - 11:59 pmDSM Des Moines-SYR Syracuse Hancock Intl

8h 58m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

6:12 am - 12:45 pmSYR Syracuse Hancock Intl-DSM Des Moines

7h 33m1 stop Philadelphia

$334American Airlines

Sat, Nov 14 - Sat, Nov 21

7:23 am - 4:47 pmDSM Des Moines-SYR Syracuse Hancock Intl

8h 24m2 stops Chicago O'Hare Intl Washington, D.C. Reagan-National

5:21 pm - 12:19 amSYR Syracuse Hancock Intl-DSM Des Moines

7h 58m2 stops Washington, D.C. Reagan-National Chicago O'Hare Intl

$339American Airlines

Sat, Oct 10 - Tue, Oct 13

3:11 pm - 11:46 pmDSM Des Moines-SYR Syracuse Hancock Intl

7h 35m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl

6:07 am - 10:31 amSYR Syracuse Hancock Intl-DSM Des Moines

5h 24m1 stop Chicago O'Hare Intl

$354United Airlines

Sat, Sep 26 - Wed, Sep 30

11:27 am - 4:54 pmDSM Des Moines-SYR Syracuse Hancock Intl

4h 27m1 stop Chicago O'Hare Intl

10:29 am - 5:48 pmSYR Syracuse Hancock Intl-DSM Des Moines

8h 19m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

$404United Airlines

Tue, Nov 10 - Sat, Nov 14

1:27 pm - 10:53 pmDSM Des Moines-SYR Syracuse Hancock Intl

8h 26m1 stop Denver Intl

5:20 pm - 9:55 pmSYR Syracuse Hancock Intl-DSM Des Moines

5h 35m1 stop Chicago O'Hare Intl

$409United Airlines

Thu, Oct 22 - Sun, Oct 25

8:43 am - 11:44 amDSM Des Moines-SYR Syracuse Hancock Intl

26h 01m2 stops Philadelphia Raleigh-Durham

9:45 pm - 12:32 pmSYR Syracuse Hancock Intl-DSM Des Moines

15h 47m1 stop Nashville Intl

$536Multiple Airlines

Booking Insights

Price, demand and travel trends for Des Moines to Syracuse flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights from Des Moines to Syracuse with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Des Moines to Syracuse?

Round-trip flights from Des Moines to Syracuse start at $329. Prices are below average for this route right now, with typical round-trip fares ranging from $343 to $436. The lowest price found in the past 5 days was $329 on Delta.

What's the cheapest day of the week to fly from Des Moines to Syracuse?

Sunday is the cheapest day of the week to fly from Des Moines to Syracuse, it is 16% cheaper than the average day. Monday is the most expensive day with flight prices 45% higher than average. Based on deals found by KAYAK users in the last 12 months.

Find deals

Low season	April
High season	December
Cheapest flight	$306

Best time to beat the crowds but there is an average 69% increase in price.

Flight from Des Moines to Syracuse

When to book flights from Des Moines to Syracuse

Are your dates flexible? Find out the best times to travel from Des Moines to Syracuse based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

Which airports can I use when flying from Des Moines to Syracuse?
Flights from Des Moines to Syracuse usually depart from Des Moines (DSM) and arrive at Syracuse Hancock Intl (SYR).
What cabin classes can I book on flights from Des Moines to Syracuse?
Only Economy Class is available on flights from Des Moines to Syracuse.
Which airports do connecting flights from Des Moines to Syracuse pass through?
One-stop flights from Des Moines to Syracuse most commonly connect through:

• Chicago O'Hare Intl (ORD) - 52% of one-stop connections
• Detroit Metropolitan Wayne County (DTW) - 34% of one-stop connections
• Charlotte Douglas (CLT) - 8% of one-stop connections
• Washington, D.C. Reagan-National (DCA) - 5% of one-stop connections

Chicago O'Hare Intl (ORD) handles the largest share of one-stop connections on this route.
Can I save money by using flexible dates for flights from Des Moines to Syracuse?
On the Des Moines to Syracuse route, being flexible with your departure day can save you up to 42%. Sunday is the cheapest day at $328 round-trip on average, while Monday is the most expensive at $565: a $237 difference. Cheaper weekend fares like these are typical of routes dominated by weekday business travel.
How long is a flight from Des Moines to Syracuse?
A nonstop flight from Des Moines to Syracuse takes 0h 00m, covering 901 miles.
Do I need a passport to fly from Des Moines to Syracuse?
No, a passport is not required for this domestic route, but you will need a real ID-compliant driver's license, a state ID, or another TSA-accepted form of identification.
Have flight prices from Des Moines to Syracuse changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route showed a wide range, from about $329 to $1,096. That means the highest observed fare was about 3x higher than the lowest one.
How are flight prices from Des Moines to Syracuse looking right now?
One-way fares from Des Moines to Syracuse are currently higher than usual. Average one-way flight prices are about $478, which is 42% above the typical average for this route.
How much time can I save by choosing a different layover airport from Des Moines to Syracuse?
Flying via Detroit Metropolitan Wayne County (DTW) gives the shortest average 1-stop total travel time at 4h 41m, compared with 5h 04m via Washington, D.C. Reagan-National (DCA) and 5h 16m via Chicago O'Hare Intl (ORD).
What is the time difference between Des Moines and Syracuse?
Syracuse is 1 hour ahead of Des Moines (Eastern Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.
What car rental options are available at Syracuse Hancock Intl Airport (SYR)?
Syracuse Hancock Intl Airport (SYR) hosts 5 major car rental companies, with daily rates starting from around $29 for economy cars. Top options include:
• Hertz
• Dollar
• Budget
• Alamo
• Avis
How much should I expect to pay for a Des Moines to Syracuse flight?
Round-trip flights from Des Moines to Syracuse range from $343 to $436, with an average of $388 over the past 12 months. Anything below $343 counts as a good deal.

If your dates can be flexible, aim for a Sunday departure instead of Monday. On this route, Sunday flights average $328 - about $237 less than Monday (42% savings) based on the last 12 months.
If you can choose when to travel, plan your Des Moines to Syracuse trip for October. Fares historically average $273 round-trip in that month - typically $385 less than the most expensive month, which is April (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Syracuse Hancock Intl Airport.
- Livaway Suites Syracuse
- DoubleTree by Hilton Hotel Syracuse
- Comfort Inn and Suites Syracuse-Carrier Circle

More options for your flight from Des Moines to Syracuse

Add a hotel or car rental

Airports

Cabin class

Direct Flights

Origins

Other destinations

Return flight

Complete your trip to Syracuse with a hotel stay or car rental

Car rentals in Syracuse

Hotels in Syracuse

Vacations in Syracuse

DSM - SYR

$277 Find Cheap Flights from Des Moines to Syracuse - Compare and Save

Everything you should know

Cheap Flights from Des Moines to Syracuse (DSM-SYR)

Recent round-trip flight deals from Des Moines to Syracuse

Recent one-way flight deals from Des Moines to Syracuse

Recent last minute flight deals from Des Moines to Syracuse

Price, demand and travel trends for Des Moines to Syracuse flights

How much is a round-trip flight from Des Moines to Syracuse?

What's the cheapest day of the week to fly from Des Moines to Syracuse?

What is the cheapest airline to fly from Des Moines to Syracuse?

What is the most popular layover airport when flying from Des Moines to Syracuse?

What is the cheapest layover airport when flying from Des Moines to Syracuse?

When flying from Des Moines to Syracuse which airport offers the shortest layover?

Key details for Des Moines to Syracuse flights

Low season

High season

Cheapest flight

When to book flights from Des Moines to Syracuse

Your Des Moines to Syracuse flight questions, answered

Your guide to booking Des Moines to Syracuse flights

More options for your flight from Des Moines to Syracuse

Complete your trip to Syracuse with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Des Moines to Syracuse

Find direct flights to and from Des Moines and Syracuse

Flights from domestic origins to Syracuse

Flights to other popular destinations

Find deals for your return flight