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Find cheap flights from Myrtle Beach to Missouri from $111

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Myrtle Beach to Missouri departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 5/25
Sat 6/1

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Best Missouri Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

St. Louis
St. Louis1 stop$244
Springfield
Springfield1 stop$435

Good to know

Low season

February

High season

July

Cheapest flight

$111
Best time to beat the crowds but there is an average 3% increase in price.
Most popular time to fly with an average 2% increase in price.
Flight from Myrtle Beach to St. Louis

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from Myrtle Beach to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Myrtle Beach to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Myrtle Beach to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Missouri from Myrtle Beach is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Myrtle Beach to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Missouri with an airline and back to Myrtle Beach with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Myrtle Beach to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Missouri from Myrtle Beach up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to Missouri

  • Morning departure is around 49% cheaper than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 4 airlines serving from Myrtle Beach to Missouri

 
Need help choosing which airline to fly with from Myrtle Beach to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 11004 reviews
8.0entertainment
7.9comfort
7.5food
8.6crew
8.2boarding
Airline reviews

I'm a larger, athletic guy (6'2", 260lbs powerlifter) and I found the seats incredibly uncomfortable with minimal leg room, especially in a window seat. Now, I full understand that being smaller may change my view but even if I was 80lbs less, my legs would be the same size and I was sandwiched between my seat and the seat in front of me.

6.0 GoodDan, Apr 2024LGA - DEN
Read more about Delta reviews

I'm a larger, athletic guy (6'2", 260lbs powerlifter) and I found the seats incredibly uncomfortable with minimal leg room, especially in a window seat. Now, I full understand that being smaller may change my view but even if I was 80lbs less, my legs would be the same size and I was sandwiched between my seat and the seat in front of me.

Horrible. This was not first class. This was a connecting flight whi h was late. My original flight never came. I hated the fact that delta gave me a connecting flight from New York to Orlando Florida. No meals and the television screens were not working. There wasn't even any power to charge your phones. This is NOT FIRST CLASS DELTA!!! Do better next time!

This flight was ridiculous. I had to have a connecting flight from New York to orlando Florida??? The flight left late and because it was a short flight there was no first class amenities. I had one alcohol drink. The flight crew was fine, but it sure did not feel like first class. Delta to me dropped the ball by giving me a connecting flight. By the time we got to Raleigh we would have missed the next flight. Lucky for me the flight never came so now I was stuck waiting for a later flight that came in late also.

Our flight was delayed in Atlanta. The staff could have gave us an explanation for the delay and how long it would be.

I liked the ease of checking in, luggage check in, wheel chair assistance, boarding and flight.

On my way home I had a layover. The flight from ATL to CLT was amended 5x while I was waiting. I could have driven home sooner. Overall from Dallas, Tx to Charlotte, NC I started my trip at 4:30pm, I didn’t get home until past midnight. I know things happen, but 5x to make me run back and forth in an airport from different terminals is excessive. I also upgraded to comfort + , I didn’t feel it was worth it. There was no benefit

On my way home I had a layover. The flight from ATL to CLT was amended 5x while I was waiting. I could have driven home sooner. Overall from Dallas, Tx to Charlotte, NC I started my trip at 4:30pm, I didn’t get home until past midnight. I know things happen, but 5x to make me run back and forth in an airport from different terminals is excessive.

They did a fine job. Can't wait to use Delta in the future.

There was a loud squeaky sound the whole time we were flying.

Had a broken tray in business class. Crew just shrugged it off.

Due to one crew member not showing up to work, our flight was significantly delayed causing us to miss our connecting flight in Houston to Mississippi causing us to be delayed by more than 6 hours and missing our event all together. Very disappointing. All because ONE crew member called in sick. United did grant us a $15 meal voucher, which was a small but appreciated concession that I wasn’t able to use because I ordered my lunch and paid for it before applying the concession, and the staff said it was too late to use it. Ugh! We also had a TWO delay coming back from Mississippi, but that was on American Airlines and it was due to weather, so not their fault. Anyway, not at all impressed with United’s handling of our flight and the HUGE disappointment of missing our important family event for our 90 year old mother. All that money and all that stress and emotions for nothing. Having to wait the hour to bring an employee from LAX seemed like something that should not have happened. Why don’t you have a local back-up? Santa Ana is not a little airport in a rural area.

Flight delayed from Cape Town to Washington then got diverted to miami and in miami we had to fend for ourselves , im still trying to get to Shreveport now

delay several times and wait extra long to board. no entertainment service because there are problem for some rows. always encounter some delays for the last flight of the day.

I just wrote a text which was supposed to be for the flight from Denver to spokane not Frankfurt to Denver.

On time every leg of the journey and exceptional staff at counter, gate, and on board. I haven’t travelled in US for a long time and was genuinely surprised how pleasant this was.

The delays (5 hrs) were a comedy of errors, and the multiple safety issues encountered were very concerning.

flight delays, staff only communicating when pushed, food service lasting a grand total of 7 minutes, stuck in seat from 45mins into flight until landing

Crew was great and did their best to make us comfortable and captain came out at the beginning to announce why the flight was delayed, weather situation up ahead, and kept us updated throughout the flight.

they made me check my carryon. There was space in the overhead bins.

Nice flight, nice crew but no cookie or napkin with my seltzer.

This flight is frequently delayed. The connections seemingly are more frequently delayed. I’ve missed connections as a result twice on the same route to charlotte then Charleston. Final destination arrival has been the next day, twice in a row. No pilots, no crew. Too many excuses. Unfortunately, my days with American are over.

Entertainment was okay not because anything was wrong but it is a short flight so having no wifi is annoying but understandable. Crew was outstanding as usual

Those seats were way too narrow. I had the middle seat, one person was a very skinny person and we still couldn’t avoid touching each other anytime one of us moved. The other person was larger and we were basically sitting in each others lap the entire flight. There was zero entertainment. The flight was long enough to justify tvs, but no. Gotta sit there in your infant seat and twiddle your thumbs.

The Flight attendant had an attitude and didn't allow anyone any time to prepare for landing despite being absent throughout the entire trip

Flight boarded without pilots. Sat on plane for 3 hrs. after over an hour late boarding. Plane never took off. Had to deplane near midnight. Line for rebooking was 3 hours + long. I had to leave.

The flight was great but board was a nightmare. The gate was changed 4 times during the layover period

The experience was great and much better than the flight going out. of course I was in first class but the service was excellent

Cold air blew constantly on my legs almost making me numb.

Missed the flight because of them and up geting a rental car

Delayd flight out of atl as always miss my conection in dfw no flight untill next day

Spirit canceled the flight in March and never notified me!

Seats suck, not enough room, overcrowded planes, hectic situation all together.

Pretty good. Would’ve been excellent if we would have left on time and the crew wasn’t late.

I do not like the customer service, I had an emergency and needed to cancel a pet reservation right after I had booked it and they would not do anything but issue a credit. I haven't flown in years as I have 7 kids and don't have spare time. I want my $125 back on my card please

Spirit airline tries to screw you at every opportunity. Spirit wanted 65$ for an extra pound in the suitcase Made me open the suitcase at the counter to remove 1 pound. Staff very cold and rude Will never fly spirit again and will recommend same to family and friends

Delayed..4 times...completely disorganized boarding. After 5 hours they scrambled to move ppl off plane bc they overbooked. Then they didn't have a cabin crew. WiFi on plane didn't work. Zero amenities. Once we boarded we sat on tarmac for an hour. Explore all alternate options including purchasing a pair of hiking boots and walking to your destination instead of flying spirit.

what I like about Spirit is that the pilot and crew are good communicators. The plane itself - well, its a budget airline and you get what is expected, But I generally just feel safer, somehow, when I know more about what is going on - and Spirit has always done a good job of telling me what is going on: why the delay, why the turbulence, why this and that... and that means a lot to me.

I paid just under 200 for flight and luggage, then paid 200 to change the flight, then paid 100 for a carry on. Then the cancelled the flight. Of the 500 I spent they refunded 250. I bought a delta flight for 270 never flew with spirit, but spirit kept 250, not even refunding the 100 for the carry on though they cancelled the flight (for weather on a day with only a slight rain ).

Flight attendants heavily pushed their affinity credit card. Very annoying

They charged me 212.00 for a heavy check in bag at the gate. The pricing and process was so confusing - as if it was designed to purposefully gouge customers who need to board plane. That experience combined with the outrageous price charged will prevent me from ever flying Spirit again. And I’ll be sure to tell the story to anyone who cares to hear.

Book cheap flights from Myrtle Beach to Missouri

Recent round-trip flight deals

5/11Sat
1 stopSpirit Airlines
7h 26mMYR-MCI
5/14Tue
1 stopSpirit Airlines
8h 50mMCI-MYR
$190
5/17Fri
1 stopSpirit Airlines
25h 34mMYR-MCI
5/20Mon
1 stopSpirit Airlines
23h 29mMCI-MYR
$200
6/4Tue
1 stopAmerican Airlines
6h 10mMYR-STL
6/5Wed
1 stopAmerican Airlines
5h 24mSTL-MYR
$269
6/4Tue
2 stopsAmerican Airlines
7h 03mMYR-STL
6/5Wed
1 stopAmerican Airlines
4h 17mSTL-MYR
$274
5/14Tue
1 stopDelta
6h 12mMYR-STL
5/18Sat
1 stopDelta
5h 06mSTL-MYR
$329
5/11Sat
2 stopsUnited Airlines
11h 18mMYR-MCI
5/14Tue
1 stopUnited Airlines
5h 14mMCI-MYR
$394
6/1Sat
3 stops
28h 54mMYR-STL
6/5Wed
3 stops
29h 33mSTL-MYR
$412
6/29Sat
3 stops
19h 25mMYR-STL
7/5Fri
1 stop
6h 35mSTL-MYR
$452
5/11Sat
1 stopDelta
4h 46mMYR-MCI
5/14Tue
2 stopsDelta
15h 54mMCI-MYR
$455
5/17Fri
1 stopUnited Airlines
26h 40mMYR-SGF
5/25Sat
1 stopUnited Airlines
23h 46mSGF-MYR
$703

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Recent one-way flight deals

5/26Sun
1 stopSpirit Airlines
5h 47mMYR-STL
$111
6/19Wed
1 stopSpirit Airlines
10h 47mMYR-MCI
$119
6/11Tue
1 stopSpirit Airlines
14h 14mMYR-MCI
$125
5/13Mon
3 stopsSpirit Airlines
29h 38mMYR-MCI
$128
5/13Mon
1 stopSpirit Airlines
8h 52mMYR-MCI
$132
6/26Wed
1 stopAmerican Airlines
4h 32mMYR-STL
$135
5/1Wed
2 stopsAmerican Airlines
7h 40mMYR-MCI
$157
5/26Sun
3 stops
24h 16mMYR-STL
$194
5/26Sun
2 stops
24h 26mMYR-STL
$219
5/17Fri
1 stopUnited Airlines
26h 40mMYR-SGF
$351

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Last minute flights from Myrtle Beach to Missouri

Last minute flight, train and bus deals

4/30Tue
multi-stopAmerican Airlines
6h 21mMYR-STL
5/2Thu
multi-stopAmerican Airlines
4h 08mSTL-MYR
$419
4/30Tue
multi-stopAmerican Airlines
7h 03mMYR-STL
5/2Thu
multi-stopAmerican Airlines
5h 57mSTL-MYR
$424
4/30Tue
multi-stopAmerican Airlines
7h 06mMYR-STL
5/2Thu
multi-stopAmerican Airlines
7h 16mSTL-MYR
$429

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Myrtle Beach - Missouri Flights

Departure:

Myrtle Beach (MYR)United States

Return flight deals:

Missouri - Myrtle Beach

Cabin classes: