Which airports can I use when flying from Cali to Guayaquil?

Flights from Cali to Guayaquil usually depart from Cali Alfonso B. Aragon Intl (CLO) and arrive at Guayaquil Jose Joaquin de Olmedo (GYE).

What cabin classes can I book on flights from Cali to Guayaquil?

Only Economy Class is available on flights from Cali to Guayaquil.

Which airports do connecting flights from Cali to Guayaquil pass through?

Connecting flights from Cali to Guayaquil most commonly pass through: • Bogotá El Dorado (BOG) - 73% of one-stop connections • Panama City Tocumen Intl (PTY) - 27% of one-stop connections

Can I save money by using flexible dates for flights from Cali to Guayaquil?

Yes. Flexible dates can save you up to 7% on flights from Cali to Guayaquil. Thursday is the cheapest departure day at $362 round-trip on average, while Monday is the most expensive at $386, a difference of $24. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How expensive are last-minute Cali to Guayaquil flights?

Last-minute fares on this route (booked within two weeks of departure) are 3% below the route average of $381. Booking late can sometimes save you money, but inventory is limited.

How long is a flight from Cali to Guayaquil?

A nonstop flight from Cali to Guayaquil takes 00m, covering 462 miles.

Do I need a passport to fly from Cali to Guayaquil?

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Have flight prices from Cali to Guayaquil changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $409 to $574. That means the highest observed fare was about 40% higher than the lowest one.

How are flight prices from Cali to Guayaquil looking right now?

One-way fares from Cali to Guayaquil are currently higher than usual. Average one-way flight prices are about $330, which is 66% above the typical average for this route.

How much time can I save by choosing a different layover airport from Cali to Guayaquil?

Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 4h 49m, compared with 5h 32m via Panama City Tocumen Intl (PTY).

What car rental options are available at Guayaquil Jose Joaquin de Olmedo Airport (GYE)?

Guayaquil Jose Joaquin de Olmedo Airport (GYE) hosts 5 major car rental companies, with daily rates starting from around $13 for economy cars. Top options include: • Europcar • Fox • Sixt • Alamo • keddy by Europcar

How much should I expect to pay for a Cali to Guayaquil flight?

Round-trip flights from Cali to Guayaquil range from $320 to $415, with an average of $381 over the past 12 months. Anything below $320 counts as a good deal.

How much is a round-trip flight from Cali to Guayaquil?

Round-trip flights from Cali to Guayaquil typically range from $320 to $415. The lowest price found in the past 5 days was $409, on Copa Airlines.

What's the cheapest day of the week to fly from Cali to Guayaquil?

Based on deals KAYAK users found in the last 12 months, Thursday is the cheapest day of the week to fly from Cali to Guayaquil. It’s 5% cheaper than the average day, while Monday is the most expensive, with prices 1% higher.

What’s the cheapest month to fly from Cali to Guayaquil?

•February is the cheapest month to fly from Cali to Guayaquil at $298 round-trip. •April ($414) and August ($386) are the most expensive months. •The price difference between flying in the cheapest and most expensive months is 38% on average. This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Cali to Guayaquil the cheapest?

Flights from Cali to Guayaquil are cheapest 13 weeks before departure. Booking in this window typically costs about 16% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Which airline is the cheapest to fly from Cali to Guayaquil?

Copa Airlines ($409) and Avianca ($412) are the cheapest airlines to fly round-trip from Cali to Guayaquil according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Cali to Guayaquil?

Bogotá El Dorado (BOG) is the most popular layover for the Cali to Guayaquil route. 73% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via BOG.

What is the cheapest layover airport when flying from Cali to Guayaquil?

Flights via Bogotá El Dorado (BOG) offer the most affordable fares, with an average round-trip price of $374. Based on KAYAK data over the past 3 months.

When flying from Cali to Guayaquil which airport offers the shortest layover?

Bogotá El Dorado (BOG) had the shortest average connection time for Cali to Guayaquil layovers at 3h 21m over the past 3 months.

$235 CHEAP FLIGHTS from Cali to Guayaquil (CLO - GYE)

Save 21% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$409

Typical prices: $320-$415

Copa Airlines

Sat 10/20Thu 10/25

CLO - GYE • 1 stop

Cheapest one-way

$235

Typical prices: $175-$236

LATAM Airlines

Fri 10/26

CLO - GYE • 2 stops

Nonstop flights

Not available

There are currently no direct flights between Cali and Guayaquil. You'll need to take a connecting flight to reach the destination.

Insights

When to book

13 weeks

in advance

Our data shows that travelers who book at least 13 weeks in advance save around 16% compared to booking last minute.

Insights

When to travel

February

Cheapest • 22% price drop

December

Most popular

Good to know

Top layover airports

Bogotá El Dorado (BOG)

Cheapest • Avg $374 (round-trip)

Panama City Tocumen Intl (PTY)

Shortest trip • 5h 32m (one-way)

Insights

Start a new search

KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to Guayaquil!

Flight Deals

Cheap Flights from Cali to Guayaquil (CLO-GYE)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Cali to Guayaquil

Tue, Oct 20 - Sun, Oct 25

8:46 am - 1:33 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

4h 47m1 stop Panama City Tocumen Intl

4:23 am - 2:11 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

9h 48m1 stop Panama City Tocumen Intl

$409Copa Airlines

Wed, Feb 3 - Sat, Feb 6

4:36 am - 11:44 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

19h 08m1 stop Panama City Tocumen Intl

4:22 am - 2:08 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

9h 46m1 stop Panama City Tocumen Intl

$409Copa Airlines

Thu, Oct 29 - Tue, Nov 3

12:09 pm - 8:53 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

8h 44m1 stop Panama City Tocumen Intl

12:25 pm - 5:04 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

4h 39m1 stop Panama City Tocumen Intl

$409Copa Airlines

Thu, Oct 29 - Tue, Nov 3

12:09 pm - 5:32 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

5h 23m1 stop Panama City Tocumen Intl

6:38 pm - 11:32 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

4h 54m1 stop Panama City Tocumen Intl

$409Copa Airlines

Sun, Oct 11 - Sat, Oct 17

6:25 pm - 1:33 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

19h 08m1 stop Panama City Tocumen Intl

6:30 pm - 5:21 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

22h 51m1 stop Panama City Tocumen Intl

$409Copa Airlines

Sun, Oct 18 - Thu, Oct 22

6:25 pm - 11:21 amCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

16h 56m1 stop Panama City Tocumen Intl

8:24 am - 5:21 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

8h 57m1 stop Panama City Tocumen Intl

$409Copa Airlines

Fri, Oct 9 - Tue, Oct 13

2:45 pm - 6:50 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

4h 05m1 stop Medellín Jose Maria Cordova Intl

9:10 am - 3:35 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

6h 25m1 stop Bogotá El Dorado

$412Avianca

Mon, Dec 7 - Thu, Dec 24

8:00 am - 3:10 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

7h 10m1 stop Bogotá El Dorado

9:10 am - 5:00 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

7h 50m1 stop Bogotá El Dorado

$413Avianca

Fri, Oct 9 - Tue, Oct 13

2:45 pm - 6:50 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

4h 05m1 stop Medellín Jose Maria Cordova Intl

9:10 am - 3:35 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

6h 25m1 stop Bogotá El Dorado

$413Avianca

Tue, Dec 1 - Fri, Dec 11

9:20 am - 3:10 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

5h 50m1 stop Bogotá El Dorado

4:20 pm - 9:30 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

5h 10m1 stop Bogotá El Dorado

$414Avianca

Recent last minute flight deals from Cali to Guayaquil

Thu, Oct 1 - Fri, Oct 2

10:10 am - 9:15 amCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

23h 05m2 stops Medellín Jose Maria Cordova Intl Quito Mariscal Sucr

3:30 am - 10:20 amGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

6h 50m1 stop Bogotá El Dorado

$399Avianca

Thu, Oct 1 - Sat, Oct 3

12:06 pm - 5:30 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

5h 24m1 stop Panama City Tocumen Intl

6:30 pm - 5:52 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

23h 22m1 stop Panama City Tocumen Intl

$409Copa Airlines

Tue, Sep 29 - Tue, Oct 6

8:48 am - 8:52 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

12h 04m1 stop Panama City Tocumen Intl

4:14 am - 5:52 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

13h 38m1 stop Panama City Tocumen Intl

$409Copa Airlines

Tue, Sep 29 - Wed, Sep 30

5:02 am - 5:30 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

12h 28m1 stop Panama City Tocumen Intl

12:22 pm - 11:06 amGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

22h 44m1 stop Panama City Tocumen Intl

$409Copa Airlines

Thu, Oct 1 - Sat, Oct 3

3:10 pm - 11:21 amCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

20h 11m1 stop Panama City Tocumen Intl

8:24 am - 2:10 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

5h 46m1 stop Panama City Tocumen Intl

$409Copa Airlines

Thu, Oct 1 - Sat, Oct 3

10:50 pm - 1:45 amCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

26h 55m2 stops Bogotá El Dorado Lima J Chavez Intl

9:00 am - 7:20 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

10h 20m2 stops Lima J Chavez Intl Bogotá El Dorado

$525LATAM Airlines

Thu, Oct 1 - Sat, Oct 3

6:45 am - 4:28 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

9h 43m2 stops Bogotá El Dorado Quito Mariscal Sucr

3:24 pm - 12:45 amGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

9h 21m2 stops Quito Mariscal Sucr Bogotá El Dorado

$546LATAM Airlines

Sun, Oct 4 - Sun, Oct 4

8:46 am - 1:33 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

4h 47m1 stop Panama City Tocumen Intl

6:30 pm - 2:10 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

19h 40m1 stop Panama City Tocumen Intl

$644Copa Airlines

Booking Insights

Price, demand and travel trends for Cali to Guayaquil flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Cali to Guayaquil? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Cali to Guayaquil departing in october.
What's the cheapest day of the week to fly from Cali to Guayaquil?: Based on deals KAYAK users found in the last 12 months, Thursday is the cheapest day of the week to fly from Cali to Guayaquil. It’s 5% cheaper than the average day, while Monday is the most expensive, with prices 1% higher.
What’s the cheapest month to fly from Cali to Guayaquil? KAYAK internal proprietary data takes all prices for each month over the last 12 months for round-trip flights from Cali to Guayaquil, removes the top 0.1% to account for outliers and then takes the median of all values for each month.: •February is the cheapest month to fly from Cali to Guayaquil at $298 round-trip.
•April ($414) and August ($386) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 38% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.
When are flights from Cali to Guayaquil the cheapest?: Flights from Cali to Guayaquil are cheapest 13 weeks before departure. Booking in this window typically costs about 16% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Low season	September
High season	December
Cheapest flight	$235

Beat the crowds with an average 16% drop in travelers.

The most popular month to fly with an average 61% increase in travelers.

One-way flight from Cali to Guayaquil

When to book flights from Cali to Guayaquil

Are your dates flexible? Find out the best times to travel from Cali to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Cali to Guayaquil?
Only Economy Class is available on flights from Cali to Guayaquil.
How long is a flight from Cali to Guayaquil?
A nonstop flight from Cali to Guayaquil takes 00m, covering 462 miles.
Do I need a passport to fly from Cali to Guayaquil?
Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.
How much should I expect to pay for a Cali to Guayaquil flight?
Round-trip flights from Cali to Guayaquil range from $320 to $415, with an average of $381 over the past 12 months. Anything below $320 counts as a good deal.
How expensive are last-minute Cali to Guayaquil flights?
Last-minute fares on this route (booked within two weeks of departure) are 3% below the route average of $381. Booking late can sometimes save you money, but inventory is limited.
Have flight prices from Cali to Guayaquil changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $409 to $574. That means the highest observed fare was about 40% higher than the lowest one.
How are flight prices from Cali to Guayaquil looking right now?
One-way fares from Cali to Guayaquil are currently higher than usual. Average one-way flight prices are about $330, which is 66% above the typical average for this route.
What car rental options are available at Guayaquil Jose Joaquin de Olmedo Airport (GYE)?
Guayaquil Jose Joaquin de Olmedo Airport (GYE) hosts 5 major car rental companies, with daily rates starting from around $13 for economy cars. Top options include:

• Europcar
• Fox
• Sixt
• Alamo
• keddy by Europcar
Which airports can I use when flying from Cali to Guayaquil?
Flights from Cali to Guayaquil usually depart from Cali Alfonso B. Aragon Intl (CLO) and arrive at Guayaquil Jose Joaquin de Olmedo (GYE).
Which airports do connecting flights from Cali to Guayaquil pass through?
Connecting flights from Cali to Guayaquil most commonly pass through:

• Bogotá El Dorado (BOG) - 73% of one-stop connections
• Panama City Tocumen Intl (PTY) - 27% of one-stop connections
Can I save money by using flexible dates for flights from Cali to Guayaquil?
Yes. Flexible dates can save you up to 7% on flights from Cali to Guayaquil. Thursday is the cheapest departure day at $362 round-trip on average, while Monday is the most expensive at $386, a difference of $24.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Cali to Guayaquil?
Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 4h 49m, compared with 5h 32m via Panama City Tocumen Intl (PTY).

If your dates are flexible, aim for a Thursday departure and avoid flying on Monday. On this route, Thursday flights average $362, about $24 less than Monday fares (6% savings) based on the last 12 months.
For the best chance at a low fare, aim to book around 13 weeks before you fly. On this route, that window historically saves about 16% versus last-minute pricing (KAYAK booking data, last 12 months).
If you can choose when to travel, plan your Cali to Guayaquil trip for February. Fares historically average $298 round-trip in that month - typically $116 less than the most expensive month, which is April (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Guayaquil Jose Joaquin de Olmedo Airport.

• Sheraton Guayaquil Hotel
• Radisson Hotel Guayaquil
• Wyndham Guayaquil Puerto Santa Ana

More options for your flight from Cali to Guayaquil

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Complete your trip to Guayaquil with a hotel stay or car rental

Car rentals in Guayaquil

Hotels in Guayaquil

CLO - GYE

$235 Find Cheap Flights from Cali to Guayaquil - Compare and Save

Everything you should know

Cheap Flights from Cali to Guayaquil (CLO-GYE)

Recent round-trip flight deals from Cali to Guayaquil

Recent one-way flight deals from Cali to Guayaquil

Recent last minute flight deals from Cali to Guayaquil

Price, demand and travel trends for Cali to Guayaquil flights

How much is a round-trip flight from Cali to Guayaquil?

What's the cheapest day of the week to fly from Cali to Guayaquil?

What’s the cheapest month to fly from Cali to Guayaquil?

When are flights from Cali to Guayaquil the cheapest?

Which airline is the cheapest to fly from Cali to Guayaquil?

What’s the most popular layover airport when flying from Cali to Guayaquil?

What is the cheapest layover airport when flying from Cali to Guayaquil?

When flying from Cali to Guayaquil which airport offers the shortest layover?

Key details for Cali to Guayaquil flights

Low season

High season

Cheapest flight

When to book flights from Cali to Guayaquil

Your Cali to Guayaquil flight questions, answered

Your guide to booking Cali to Guayaquil flights

More options for your flight from Cali to Guayaquil

Complete your trip to Guayaquil with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Cali to Guayaquil

Find direct flights to and from Cali and Guayaquil

Flights to other popular destinations

Find deals for your return flight