Which airports can I use when flying from Cali to Guayaquil?

Flights from Cali to Guayaquil usually depart from Cali Alfonso B. Aragon Intl (CLO) and arrive at Guayaquil Jose Joaquin de Olmedo (GYE).

What cabin classes can I book on flights from Cali to Guayaquil?

Only Economy Class is available on flights from Cali to Guayaquil.

Which airports do connecting flights from Cali to Guayaquil pass through?

One-stop flights from Cali to Guayaquil most commonly connect through: • Bogotá El Dorado (BOG) - 72% of one-stop connections • Panama City Tocumen Intl (PTY) - 28% of one-stop connections • Medellín Jose Maria Cordova Intl (MDE) - 0% of one-stop connections

Can I save money by using flexible dates for flights from Cali to Guayaquil?

Yes. Flexible dates can save you up to 5% on flights from Cali to Guayaquil. Thursday is the cheapest departure day at $370 round-trip on average, while Wednesday is the most expensive at $387, a difference of $17. KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

How expensive are last-minute Cali to Guayaquil flights?

Last-minute fares on this route (booked within two weeks of departure) are 2% below the route average of $382. Booking late can sometimes save you money, but inventory is limited.

How long is a flight from Cali to Guayaquil?

A nonstop flight from Cali to Guayaquil takes 00m, covering 462 miles.

Do I need a passport to fly from Cali to Guayaquil?

Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

Have flight prices from Cali to Guayaquil changed much recently?

Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $376 to $570. That means the highest observed fare was about 51% higher than the lowest one.

How are flight prices from Cali to Guayaquil looking right now?

One-way fares from Cali to Guayaquil are currently higher than usual. Average one-way flight prices are about $270, which is 27% above the typical average for this route.

How much time can I save by choosing a different layover airport from Cali to Guayaquil?

Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 4h 52m, compared with 5h 06m via Medellín Jose Maria Cordova Intl (MDE) and 5h 32m via Panama City Tocumen Intl (PTY).

What car rental options are available at Guayaquil Jose Joaquin de Olmedo Airport (GYE)?

Guayaquil Jose Joaquin de Olmedo Airport (GYE) hosts 5 major car rental companies, with daily rates starting from around $13 for economy cars. Top options include: • Europcar • Fox • Sixt • Alamo • keddy by Europcar

How much should I expect to pay for a Cali to Guayaquil flight?

Round-trip flights from Cali to Guayaquil range from $323 to $414, with an average of $382 over the past 12 months. Anything below $323 counts as a good deal.

How much is a round-trip flight from Cali to Guayaquil?

Round-trip flights from Cali to Guayaquil typically range from $323 to $414. The lowest price found in the past 5 days was $376, on LATAM Airlines.

What's the cheapest day of the week to fly from Cali to Guayaquil?

Based on deals KAYAK users found in the last 12 months, Thursday is the cheapest day of the week to fly from Cali to Guayaquil. It’s 4% cheaper than the average day, while Wednesday is the most expensive, with prices 1% higher.

What’s the cheapest month to fly from Cali to Guayaquil?

•February is the cheapest month to fly from Cali to Guayaquil at $298 round-trip. •April ($413) and September ($389) are the most expensive months. •The price difference between flying in the cheapest and most expensive months is 38% on average. This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Cali to Guayaquil the cheapest?

Flights from Cali to Guayaquil are cheapest 13 weeks before departure. Booking in this window typically costs about 11% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Which airline is the cheapest to fly from Cali to Guayaquil?

LATAM Airlines ($376) and Copa Airlines ($409) are the cheapest airlines to fly round-trip from Cali to Guayaquil according to KAYAK data over the last 5 days.

What’s the most popular layover airport when flying from Cali to Guayaquil?

Bogotá El Dorado (BOG) is the most popular layover for the Cali to Guayaquil route. 72% of KAYAK users who booked 1-stop round-trips over the past 3 months connected via BOG.

What is the cheapest layover airport when flying from Cali to Guayaquil?

Flights via Bogotá El Dorado (BOG) offer the most affordable fares, with an average round-trip price of $376. Based on KAYAK data over the past 3 months.

When flying from Cali to Guayaquil which airport offers the shortest layover?

Bogotá El Dorado (BOG) had the shortest average connection time for Cali to Guayaquil layovers at 3h 24m over the past 3 months.

$203 CHEAP FLIGHTS from Cali to Guayaquil (CLO - GYE)

Save 19% or more on flights. Compare deals from all over the web.

Never overpay with our price tracking tools.

Filter searches by price, airline and more to find your best flights.

Cheapest round-trip

$376

Typical prices: $323-$414

LATAM Airlines

Sat 12/1Tue 12/11

CLO - GYE • 2 stops

Cheapest one-way

$203

Typical prices: $182-$239

LATAM Airlines

Fri 11/30

CLO - GYE • 2 stops

Nonstop flights

Not available

There are currently no direct flights between Cali and Guayaquil. You'll need to take a connecting flight to reach the destination.

Insights

When to book

13 weeks

in advance

Our data shows that travelers who book at least 13 weeks in advance save around 11% compared to booking last minute.

Insights

When to travel

February

Cheapest • 22% price drop

December

Most popular

Good to know

Top layover airports

Bogotá El Dorado (BOG)

Cheapest • Avg $376 (round-trip)

Medellín Jose Maria Cordova Intl (MDE)

Shortest trip • 5h 06m (one-way)

Insights

Start a new search

KAYAK searches 100s of sites at once to find you the best travel deals.

We hope you love your trip to Guayaquil!

Flight Deals

Cheap Flights from Cali to Guayaquil (CLO-GYE)

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Recent round-trip flight deals from Cali to Guayaquil

Tue, Dec 1 - Fri, Dec 11

5:25 pm - 7:46 amCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

14h 21m2 stops Bogotá El Dorado Quito Mariscal Sucr

2:01 pm - 6:15 amGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

16h 14m2 stops Quito Mariscal Sucr Bogotá El Dorado

$376LATAM Airlines

Mon, Dec 7 - Thu, Dec 24

5:25 pm - 8:51 amCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

15h 26m2 stops Bogotá El Dorado Quito Mariscal Sucr

7:06 pm - 11:35 amGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

16h 29m2 stops Quito Mariscal Sucr Bogotá El Dorado

$399LATAM Airlines

Tue, Dec 1 - Fri, Dec 11

5:25 pm - 9:37 amCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

16h 12m2 stops Bogotá El Dorado Quito Mariscal Sucr

2:01 pm - 11:40 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

9h 39m2 stops Quito Mariscal Sucr Bogotá El Dorado

$399LATAM Airlines

Tue, Dec 1 - Fri, Dec 11

11:20 pm - 4:53 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

17h 33m2 stops Bogotá El Dorado Quito Mariscal Sucr

2:01 pm - 11:40 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

9h 39m2 stops Quito Mariscal Sucr Bogotá El Dorado

$404LATAM Airlines

Thu, Apr 1 - Sat, Apr 17

5:09 am - 1:53 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

8h 44m1 stop Panama City Tocumen Intl

5:19 am - 2:14 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

8h 55m1 stop Panama City Tocumen Intl

$409Copa Airlines

Thu, Oct 29 - Mon, Nov 2

6:15 pm - 11:15 amCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

17h 00m1 stop Panama City Tocumen Intl

4:22 am - 5:32 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

13h 10m1 stop Panama City Tocumen Intl

$409Copa Airlines

Mon, Oct 19 - Sun, Oct 25

6:25 pm - 1:33 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

19h 08m1 stop Panama City Tocumen Intl

6:40 pm - 11:02 amGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

16h 22m1 stop Panama City Tocumen Intl

$409Copa Airlines

Wed, Nov 4 - Sun, Nov 22

8:42 am - 5:35 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

8h 53m1 stop Panama City Tocumen Intl

8:25 am - 5:04 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

8h 39m1 stop Panama City Tocumen Intl

$409Copa Airlines

Mon, Dec 7 - Wed, Dec 23

9:20 am - 3:10 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

5h 50m1 stop Bogotá El Dorado

3:30 am - 11:30 amGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

8h 00m1 stop Bogotá El Dorado

$413Avianca

Tue, Dec 1 - Thu, Dec 10

12:15 pm - 6:25 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

6h 10m1 stop Bogotá El Dorado

3:30 am - 9:45 amGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

6h 15m1 stop Bogotá El Dorado

$413Avianca

Recent last minute flight deals from Cali to Guayaquil

Mon, Oct 12 - Wed, Nov 11

12:06 pm - 11:37 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

11h 31m1 stop Panama City Tocumen Intl

4:22 am - 5:04 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

12h 42m1 stop Panama City Tocumen Intl

$409Copa Airlines

Wed, Oct 14 - Fri, Oct 16

12:06 pm - 12:01 amCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

11h 55m1 stop Panama City Tocumen Intl

12:18 pm - 5:52 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

5h 34m1 stop Panama City Tocumen Intl

$409Copa Airlines

Fri, Oct 9 - Tue, Oct 13

12:06 pm - 8:52 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

8h 46m1 stop Panama City Tocumen Intl

6:30 pm - 5:21 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

22h 51m1 stop Panama City Tocumen Intl

$409Copa Airlines

Mon, Oct 12 - Tue, Oct 13

12:06 pm - 11:37 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

11h 31m1 stop Panama City Tocumen Intl

6:30 pm - 11:06 amGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

16h 36m1 stop Panama City Tocumen Intl

$409Copa Airlines

Sat, Oct 10 - Tue, Oct 20

12:06 pm - 5:30 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

5h 24m1 stop Panama City Tocumen Intl

2:33 pm - 2:10 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

23h 37m1 stop Panama City Tocumen Intl

$409Copa Airlines

Wed, Oct 14 - Tue, Oct 20

12:06 pm - 8:52 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

8h 46m1 stop Panama City Tocumen Intl

11:44 am - 11:37 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

11h 53m1 stop Panama City Tocumen Intl

$409Copa Airlines

Fri, Oct 9 - Tue, Oct 13

5:00 am - 11:21 amCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

6h 21m1 stop Panama City Tocumen Intl

6:30 pm - 2:10 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

19h 40m1 stop Panama City Tocumen Intl

$410Copa Airlines

Fri, Oct 9 - Tue, Oct 13

2:45 pm - 6:50 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

4h 05m1 stop Medellín Jose Maria Cordova Intl

9:10 am - 3:35 pmGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

6h 25m1 stop Bogotá El Dorado

$412Avianca

Fri, Oct 9 - Mon, Oct 12

8:25 am - 5:35 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

9h 10m1 stop Bogotá El Dorado

3:30 am - 9:00 amGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

5h 30m1 stop Bogotá El Dorado

$414Avianca

Fri, Oct 9 - Mon, Oct 12

8:25 am - 3:55 pmCLO Cali Alfonso B. Aragon Intl-GYE Guayaquil Jose Joaquin de Olmedo

7h 30m2 stops Bogotá El Dorado Quito Mariscal Sucr

3:30 am - 10:20 amGYE Guayaquil Jose Joaquin de Olmedo-CLO Cali Alfonso B. Aragon Intl

6h 50m1 stop Bogotá El Dorado

$434Avianca

Booking Insights

Price, demand and travel trends for Cali to Guayaquil flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

Prices

Airlines

Layovers

How much is a round-trip flight from Cali to Guayaquil? This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Cali to Guayaquil departing in december.
What's the cheapest day of the week to fly from Cali to Guayaquil?: Based on deals KAYAK users found in the last 12 months, Thursday is the cheapest day of the week to fly from Cali to Guayaquil. It’s 4% cheaper than the average day, while Wednesday is the most expensive, with prices 1% higher.
What’s the cheapest month to fly from Cali to Guayaquil? KAYAK internal proprietary data takes all prices for each month over the last 12 months for round-trip flights from Cali to Guayaquil, removes the top 0.1% to account for outliers and then takes the median of all values for each month.: •February is the cheapest month to fly from Cali to Guayaquil at $298 round-trip.
•April ($413) and September ($389) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 38% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.
When are flights from Cali to Guayaquil the cheapest?: Flights from Cali to Guayaquil are cheapest 13 weeks before departure. Booking in this window typically costs about 11% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Find deals

Low season	September
High season	December
Cheapest flight	$203

Beat the crowds with an average 29% drop in travelers.

The most popular month to fly with an average 62% increase in travelers.

One-way flight from Cali to Guayaquil

When to book flights from Cali to Guayaquil

Are your dates flexible? Find out the best times to travel from Cali to Guayaquil based on our flight data from the last year. Discover the cheapest month and even day to fly.

Estimated round-trip price

KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

What cabin classes can I book on flights from Cali to Guayaquil?
Only Economy Class is available on flights from Cali to Guayaquil.
How long is a flight from Cali to Guayaquil?
A nonstop flight from Cali to Guayaquil takes 00m, covering 462 miles.
Do I need a passport to fly from Cali to Guayaquil?
Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.
How much should I expect to pay for a Cali to Guayaquil flight?
Round-trip flights from Cali to Guayaquil range from $323 to $414, with an average of $382 over the past 12 months. Anything below $323 counts as a good deal.
How expensive are last-minute Cali to Guayaquil flights?
Last-minute fares on this route (booked within two weeks of departure) are 2% below the route average of $382. Booking late can sometimes save you money, but inventory is limited.
Have flight prices from Cali to Guayaquil changed much recently?
Yes. Based on fares seen in the past 5 days, round-trip prices on this route varied from about $376 to $570. That means the highest observed fare was about 51% higher than the lowest one.
How are flight prices from Cali to Guayaquil looking right now?
One-way fares from Cali to Guayaquil are currently higher than usual. Average one-way flight prices are about $270, which is 27% above the typical average for this route.
What car rental options are available at Guayaquil Jose Joaquin de Olmedo Airport (GYE)?
Guayaquil Jose Joaquin de Olmedo Airport (GYE) hosts 5 major car rental companies, with daily rates starting from around $13 for economy cars. Top options include:

• Europcar
• Fox
• Sixt
• Alamo
• keddy by Europcar
Which airports can I use when flying from Cali to Guayaquil?
Flights from Cali to Guayaquil usually depart from Cali Alfonso B. Aragon Intl (CLO) and arrive at Guayaquil Jose Joaquin de Olmedo (GYE).
Which airports do connecting flights from Cali to Guayaquil pass through?
One-stop flights from Cali to Guayaquil most commonly connect through:

• Bogotá El Dorado (BOG) - 72% of one-stop connections
• Panama City Tocumen Intl (PTY) - 28% of one-stop connections
• Medellín Jose Maria Cordova Intl (MDE) - 0% of one-stop connections
Can I save money by using flexible dates for flights from Cali to Guayaquil?
Yes. Flexible dates can save you up to 5% on flights from Cali to Guayaquil. Thursday is the cheapest departure day at $370 round-trip on average, while Wednesday is the most expensive at $387, a difference of $17.

KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.
How much time can I save by choosing a different layover airport from Cali to Guayaquil?
Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 4h 52m, compared with 5h 06m via Medellín Jose Maria Cordova Intl (MDE) and 5h 32m via Panama City Tocumen Intl (PTY).

If your dates are flexible, aim for a Thursday departure and avoid flying on Wednesday. On this route, Thursday flights average $370, about $17 less than Wednesday fares (4% savings) based on the last 12 months.
For the best chance at a low fare, aim to book around 13 weeks before you fly. On this route, that window historically saves about 11% versus last-minute pricing (KAYAK booking data, last 12 months).
If you can choose when to travel, plan your Cali to Guayaquil trip for February. Fares historically average $298 round-trip in that month - typically $115 less than the most expensive month, which is April (based on the last 12 months).
If you're arriving late at night and need somewhere to stay, check out these hotels close to Guayaquil Jose Joaquin de Olmedo Airport.

• Radisson Hotel Guayaquil
• Sheraton Guayaquil Hotel
• Wyndham Guayaquil Puerto Santa Ana

More options for your flight from Cali to Guayaquil

Add a hotel or car rental

Airports

Cabin class

Direct Flights

Other destinations

Return flight

Complete your trip to Guayaquil with a hotel stay or car rental

Car rentals in Guayaquil

Hotels in Guayaquil

CLO - GYE

$203 Find Cheap Flights from Cali to Guayaquil - Compare and Save

Everything you should know

Cheap Flights from Cali to Guayaquil (CLO-GYE)

Recent round-trip flight deals from Cali to Guayaquil

Recent one-way flight deals from Cali to Guayaquil

Recent last minute flight deals from Cali to Guayaquil

Price, demand and travel trends for Cali to Guayaquil flights

How much is a round-trip flight from Cali to Guayaquil?

What's the cheapest day of the week to fly from Cali to Guayaquil?

What’s the cheapest month to fly from Cali to Guayaquil?

When are flights from Cali to Guayaquil the cheapest?

Which airline is the cheapest to fly from Cali to Guayaquil?

What’s the most popular layover airport when flying from Cali to Guayaquil?

What is the cheapest layover airport when flying from Cali to Guayaquil?

When flying from Cali to Guayaquil which airport offers the shortest layover?

Key details for Cali to Guayaquil flights

Low season

High season

Cheapest flight

When to book flights from Cali to Guayaquil

Your Cali to Guayaquil flight questions, answered

Your guide to booking Cali to Guayaquil flights

More options for your flight from Cali to Guayaquil

Complete your trip to Guayaquil with a hotel stay or car rental

Information on your arrival and departure airports

Cabin class types available on flights from Cali to Guayaquil

Find direct flights to and from Cali and Guayaquil

Flights to other popular destinations

Find deals for your return flight