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$109 Find cheap flights from South Carolina to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Panama City departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/29
Sat 7/6

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Good to know

Low season

October

High season

December

Cheapest flight

$109
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly with an average 48% increase in price.
Flight from Greenville to Panama City

FAQs for booking flights from South Carolina to Panama City

  • How does KAYAK find such low prices on flights from South Carolina to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to South Carolina with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from South Carolina to Panama City?

Find which airlines fly direct from South Carolina to Tocumen Intl, which days they fly and book direct flights.

Nonstop departures

South Carolina to Panama City Tocumen Intl

Monday

Air Europa, Air France, American Airlines, +19 more

Air Europa, Air France, +20 more

Tuesday

Air Europa, Air France, American Airlines, +15 more

Air Europa, Air France, +16 more

Wednesday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Thursday

Air Europa, Air France, American Airlines, +15 more

Air Europa, Air France, +16 more

Friday

Air Europa, Air France, American Airlines, +14 more

Air Europa, Air France, +15 more

Saturday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Sunday

Air Europa, Air France, American Airlines, +18 more

Air Europa, Air France, +19 more

See more direct flights

Nonstop returns

Panama City Tocumen Intl to South Carolina

Monday

Air Europa, Air France, American Airlines, +19 more

Air Europa, Air France, +20 more

Tuesday

Air Europa, Air France, American Airlines, +15 more

Air Europa, Air France, +16 more

Wednesday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Thursday

Air Europa, Air France, American Airlines, +15 more

Air Europa, Air France, +16 more

Friday

Air Europa, Air France, American Airlines, +14 more

Air Europa, Air France, +15 more

Saturday

Air Europa, Air France, American Airlines, +16 more

Air Europa, Air France, +17 more

Sunday

Air Europa, Air France, American Airlines, +18 more

Air Europa, Air France, +19 more

See more direct flights
See more direct flights

Book cheap flights from South Carolina to Panama City

Recent round-trip flight deals

10/10Thu
1 stopUnited Airlines
12h 37mGSP-PTY
10/14Mon
1 stopUnited Airlines
29h 19mPTY-GSP
$289
9/19Thu
1 stopUnited Airlines
12h 37mGSP-PTY
9/22Sun
1 stopUnited Airlines
28h 44mPTY-GSP
$293
10/31Thu
1 stopUnited Airlines
10h 07mCHS-PTY
11/5Tue
1 stopUnited Airlines
12h 59mPTY-CHS
$302
6/12Wed
1 stopUnited Airlines
9h 29mCHS-PTY
6/21Fri
1 stopUnited Airlines
13h 05mPTY-CHS
$313
9/19Thu
2 stopsAmerican Airlines
18h 57mGSP-PTY
9/22Sun
2 stopsAmerican Airlines
20h 14mPTY-GSP
$325
10/31Thu
2 stopsAmerican Airlines
17h 23mCHS-PTY
11/5Tue
1 stopAmerican Airlines
6h 34mPTY-CHS
$326
9/7Sat
1 stopDelta
6h 52mCAE-PTY
9/11Wed
1 stopDelta
8h 39mPTY-CAE
$398
8/22Thu
2 stops
30h 09mCLT-PTY
8/25Sun
2 stops
34h 13mPTY-CLT
$405
9/4Wed
1 stopDelta
6h 52mCLT-PTY
9/10Tue
1 stopDelta
8h 35mPTY-CLT
$412
9/6Fri
2 stops
30h 09mCLT-PTY
9/9Mon
2 stops
34h 13mPTY-CLT
$423

Search by stops

Search by airline

Search by price

Recent one-way flight deals

7/15Mon
1 stopUnited Airlines
10h 06mGSP-PTY
$109
7/15Mon
2 stopsAmerican Airlines
21h 10mGSP-PTY
$125
6/8Sat
2 stopsAmerican Airlines
10h 19mMYR-PTY
$195
6/8Sat
1 stopDelta
6h 31mMYR-PTY
$197
6/12Wed
2 stops
27h 24mCLT-PTY
$197
6/18Tue
2 stops
28h 47mCLT-PTY
$204
7/20Sat
1 stopDelta
6h 39mCLT-PTY
$213
6/13Thu
2 stops
28h 47mCLT-PTY
$220
6/12Wed
3 stops
25h 19mCLT-PTY
$222
6/12Wed
1 stopAmerican Airlines
6h 15mCLT-PTY
$233

Search by stops

Search by airline

Search by price

Last minute flights from South Carolina to Panama City

Last minute flight, train and bus deals

6/3Mon
multi-stop
25h 22mCLT-PTY
6/11Tue
multi-stop
18h 51mPTY-CLT
$573
6/3Mon
multi-stop
25h 22mCLT-PTY
6/11Tue
multi-stop
33h 45mPTY-CLT
$587
6/3Mon
multi-stopUnited Airlines
10h 39mCLT-PTY
6/11Tue
multi-stopUnited Airlines
9h 01mPTY-CLT
$592
6/2Sun
multi-stopUnited Airlines
10h 39mCLT-PTY
6/8Sat
multi-stopUnited Airlines
10h 51mPTY-CLT
$632
6/3Mon
multi-stop
22h 52mCLT-PTY
6/11Tue
multi-stop
23h 58mPTY-CLT
$668
6/3Mon
multi-stop
28h 52mCLT-PTY
6/11Tue
multi-stop
9h 07mPTY-CLT
$685
6/2Sun
multi-stopAmerican Airlines
19h 29mCLT-PTY
6/8Sat
multi-stopAmerican Airlines
22h 07mPTY-CLT
$772
6/2Sun
multi-stopAmerican Airlines
17h 23mCLT-PTY
6/8Sat
multi-stopAmerican Airlines
22h 07mPTY-CLT
$940
5/31Fri
multi-stopDelta
12h 23mCLT-PTY
6/8Sat
multi-stopDelta
8h 37mPTY-CLT
$1,502

Search by stops

Search by airline

Search by price

Flights to Panama City

Destination:

Panama City (PTY)Panama

Return flight deals:

Panama City - South Carolina

Cabin classes: