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Find cheap flights from South Carolina to Panama from $109

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from South Carolina to Panama departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/29
Sat 7/6

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In the last 7 days travelers have searched 42,686,544 times on KAYAK, and here is why:

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Good to know

Low season

October

High season

December

Cheapest flight

$109
Best time to beat the crowds with an average 2% drop in price.
Most popular time to fly with an average 68% increase in price.
Flight from Greenville to Panama City

FAQs for booking flights from South Carolina to Panama

  • How does KAYAK find such low prices on flights from South Carolina to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama with an airline and back to South Carolina with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Book cheap flights from South Carolina to Panama

Recent round-trip flight deals

10/10Thu
1 stopUnited Airlines
12h 37mGSP-PTY
10/14Mon
1 stopUnited Airlines
29h 19mPTY-GSP
$289
9/19Thu
1 stopUnited Airlines
12h 37mGSP-PTY
9/22Sun
1 stopUnited Airlines
28h 44mPTY-GSP
$293
10/31Thu
1 stopUnited Airlines
10h 07mCHS-PTY
11/5Tue
1 stopUnited Airlines
12h 59mPTY-CHS
$302
6/12Wed
1 stopUnited Airlines
9h 29mCHS-PTY
6/21Fri
1 stopUnited Airlines
13h 05mPTY-CHS
$313
9/19Thu
2 stopsAmerican Airlines
18h 57mGSP-PTY
9/22Sun
2 stopsAmerican Airlines
20h 14mPTY-GSP
$325
10/31Thu
2 stopsAmerican Airlines
17h 23mCHS-PTY
11/5Tue
1 stopAmerican Airlines
6h 34mPTY-CHS
$326
9/7Sat
1 stopDelta
6h 52mCAE-PTY
9/11Wed
1 stopDelta
8h 39mPTY-CAE
$398
8/22Thu
2 stops
30h 09mCLT-PTY
8/25Sun
2 stops
34h 13mPTY-CLT
$405
9/4Wed
1 stopDelta
6h 52mCLT-PTY
9/10Tue
1 stopDelta
8h 35mPTY-CLT
$412
9/6Fri
2 stops
30h 09mCLT-PTY
9/9Mon
2 stops
34h 13mPTY-CLT
$423

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Recent one-way flight deals

7/15Mon
1 stopUnited Airlines
10h 06mGSP-PTY
$109
7/15Mon
2 stopsAmerican Airlines
21h 10mGSP-PTY
$125
6/8Sat
2 stopsAmerican Airlines
10h 19mMYR-PTY
$195
6/8Sat
1 stopDelta
6h 31mMYR-PTY
$197
6/12Wed
2 stops
27h 24mCLT-PTY
$197
6/18Tue
2 stops
28h 47mCLT-PTY
$204
7/20Sat
1 stopDelta
6h 39mCLT-PTY
$213
6/13Thu
2 stops
28h 47mCLT-PTY
$220
6/12Wed
3 stops
25h 19mCLT-PTY
$222
6/12Wed
1 stopAmerican Airlines
6h 15mCLT-PTY
$233

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Last minute flights from South Carolina to Panama

Last minute flight, train and bus deals

6/3Mon
multi-stop
25h 22mCLT-PTY
6/11Tue
multi-stop
18h 51mPTY-CLT
$573
6/3Mon
multi-stop
25h 22mCLT-PTY
6/11Tue
multi-stop
33h 45mPTY-CLT
$587
6/3Mon
multi-stopUnited Airlines
10h 39mCLT-PTY
6/11Tue
multi-stopUnited Airlines
9h 01mPTY-CLT
$592
6/2Sun
multi-stopUnited Airlines
10h 39mCLT-PTY
6/8Sat
multi-stopUnited Airlines
10h 51mPTY-CLT
$632
6/3Mon
multi-stop
22h 52mCLT-PTY
6/11Tue
multi-stop
23h 58mPTY-CLT
$668
6/3Mon
multi-stop
28h 52mCLT-PTY
6/11Tue
multi-stop
9h 07mPTY-CLT
$685
6/2Sun
multi-stopAmerican Airlines
19h 29mCLT-PTY
6/8Sat
multi-stopAmerican Airlines
22h 07mPTY-CLT
$772
6/2Sun
multi-stopAmerican Airlines
17h 23mCLT-PTY
6/8Sat
multi-stopAmerican Airlines
22h 07mPTY-CLT
$940
5/31Fri
multi-stopDelta
12h 23mCLT-PTY
6/8Sat
multi-stopDelta
8h 37mPTY-CLT
$1,502

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Flights to Panama

Return flight deals:

Panama - South Carolina

Cabin classes: