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Find cheap flights from John Wayne (Santa Ana) to Missouri from $72

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Missouri departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Thu 7/11
Thu 7/18

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Best Missouri Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

St. Louis
St. Louis1 stop$150
Springfield
Springfield1 stop$283

Good to know

Low season

February

High season

June

Cheapest flight

$72
Best time to beat the crowds with an average 30% drop in price.
Most popular time to fly with an average 18% increase in price.
Flight from Santa Ana to St. Louis

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Missouri from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Missouri with an airline and back to John Wayne (Santa Ana) with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Missouri from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to Missouri

  • Morning departure is around 13% more expensive than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from Santa Ana to Missouri

Need help choosing which airline to fly with from Santa Ana to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
Alaska AirlinesOverall score based on 9267 reviews
7.3Food
8.6Crew
7.9Comfort
8.2Boarding
7.3Entertainment
Airline reviews

Soda cans were mini-size; snacks were teeny. Options for entertainment on trans-continent flights were bad - no seat screens and no way to support device (as seen on other airlines) so had to hold device in position. Just overall, not good (compared to United)

6.0 Goodkaren, Jun 2024LAX - IAD
Read more about Alaska Airlines reviews

Soda cans were mini-size; snacks were teeny. Options for entertainment on trans-continent flights were bad - no seat screens and no way to support device (as seen on other airlines) so had to hold device in position. Just overall, not good (compared to United)

I like the big picture of the Eskimo on the tail of the plane.

Everything was great but there were no entertainment options available.

Flight was delayed 2 hours. It was too cold inside the cabin. My seat mate had no jacket so she was shivering the entire flight. The stewardess says there’s no available blanket.

The plane had to sit on the tarmac for 45 minutes once it had landed. Not Alaska’s fault.

No prob with entertainment-would have selected n/a if it had been an option. No entertainment-flight was only a short hop. Great flight,

I love having assigned seats and being able to check bags at the gate, if needed. Both are super-helpful when traveling with a toddler!!!

It was really good and that's why we choose AA over other airlines.

Seats are uncomfortable but let room was adequate. The snack is pretty weak and the staff not particularly friendly.

Flight was cancelled just before we boarded. I had to stayed an extra night in SF and arrived one day late. Also I had to flight back JFK and not Newark since they didn't have flight to Newark until very late the following day. A real bad experience on this flight. It took me 2 days to get back home.

There was plenty of overhead room but half of the passengers were told they had to check their carryon bags. My partner and I checked in as early as possible and our seats were split across the aisle.

Flew first class so everything was great. But maybe because the flights were red eye, no meals were served, just chips. I flew Alaska Air 1st class at 9PM (2 hour flight) and they served beef short rib sliders!

There was a loud squeaky sound the whole time we were flying.

On 2 different flights the wifi was horrible and there was no drink or snack service.

I didn’t not like that I could not select my seat and ended up with the worse seat.

The landing was bad and the hostess came two times and i was sleeping but when she served the person that nexts to me I woke up and she didn’t even asked me if I need any drink or snacks two times!!!!

Plane was late because of a mechanical malfunction and the food listed as available was not. Flight attendants seem over worked and under paid. They just done seem happy. And that can be seen in their faces.

Waited 3 hours on a plane to de-ice due to manpower issues. Waited another hour and a half once we landed because of a gate issue. Missed my connections. Created. A total of 13 hours of delay.

There was no FREE wi-fi nor entertainment screens at all.

Great, on time departure, friendly and accommodating crew, great leg room, Smith flight

The entertainment wasn’t playing in the app or online.

Horrible, the flights kept delaying, so it is obvious that we won't be able to make it to the next connection. No easier/real agent on site to help you figure this out. UA agent on other counters refuse to assist you and direct us to use the QR code/call customer service. So inefficient and poor. While technology seems convenient, but it's not the best interest/experience for customers need help while there is active issue need assistance.

Flight was delayed due to the late arrival of the catering truck, which is quite unacceptable. There was a beverage service, but no pretzel, or cookie, or nuts were served in coach.

I had a great flight. Everything went smoothly and the flight arrived early.

On time take off…US cabins look tired and need of refresh!

I paid $380 for my one-way ticket from California to Minnesota. The fair did not include online check-in. I received instructions from their app to check in at a kiosk. At the kiosk, the boarding pass would not print until an actual person came to verify that I had a personal item and not a carry-on item, On the plane, the person next to me was drunk and allowed to continue to order alcohol. United is garbage I’d rather fly spirit.

Do not like the feeling of being in the basic economy. Everyone should feel good no matter what.

Terrible! The plane was old and you are required to connect your own device to their Wi-Fi rather than have entertainment options in the back of the seat in front of you. The Wi-Fi went out during the flight and there was only one plug for the devices every two seats. Three out of five surrounding my family did not work. The seats and spaces under them were so small I could not fit my backpack, which I’ve always brought on flights and fit before no problem. The crew were unpleasant and patronizing.

Last minute gate change nearly caused us to miss our flight. Change was not announced or displayed in the main board at the old gate. Terrible communication. When we landed we had to wait 20 minutes because there was another plane at the assigned gate. Not the crew’s fault, but adding 20 minutes to a 45 minute flight sucked.

Due to one crew member not showing up to work, our flight was significantly delayed causing us to miss our connecting flight in Houston to Mississippi causing us to be delayed by more than 6 hours and missing our event all together. Very disappointing. All because ONE crew member called in sick. United did grant us a $15 meal voucher, which was a small but appreciated concession that I wasn’t able to use because I ordered my lunch and paid for it before applying the concession, and the staff said it was too late to use it. Ugh! We also had a TWO delay coming back from Mississippi, but that was on American Airlines and it was due to weather, so not their fault. Anyway, not at all impressed with United’s handling of our flight and the HUGE disappointment of missing our important family event for our 90 year old mother. All that money and all that stress and emotions for nothing. Having to wait the hour to bring an employee from LAX seemed like something that should not have happened. Why don’t you have a local back-up? Santa Ana is not a little airport in a rural area.

The flight was delayed several times without explanation. The seats were terribly uncomfortable and wifi isn’t included. All these make for a less than ideal flight.

The flights was delayed by hours and it was the firmest landing I have experienced in my life. My back is still sore.

Internet service was erratic. Crew service was poor and slow. My luggage on this non-stop flight was lost and not recovered

Flight was 1/2 hour delayed leaving Phoenix. Otherwise it was an average flight. Flight crew on this trip was very nice.

Horrible - they lied to me about baggage & boarding, even though I specifically spoke to their agents the day before my flight about my issue. When I showed up they did not let me board and stranded me at my airport until I bought a new flight with money I did not have to spend.

The experience was great and much better than the flight going out. of course I was in first class but the service was excellent

Comfort of seats, ease of boarding. Food selection could be better

Food options were limited which is absolutely embarrassing for a Flight of this size The staff did not come around as much and I am not accustomed to such poor service from American Airlines Drinks I believe were limited to soda and water

Crew were attentive and friendly. Flight was smooth and early! I enjoyed the less crowded plane. Thank you!

We are gluten free, there were not any available complimentary gluten free options.

My flight was uncomfortable and crammed. There were no pockets to store things, I couldn’t move my seat back slightly. Beverages including soda cost extra. My husband flew on another spirit airline flight, which was delayed a total of 48 hours, only to be canceled.

Flight was canceled less than 6 hours before takeoff, rebooked on a flight that was twice as long and left earlier so we couldn’t make it, when using text support option took over 2 hours to speak with someone.

Terrible legroom, seats do not recline, tray table the size of an iPhone, delayed flight, have to pay 5$ to get a cup of water onboard.

The crew was the best and very accommodating I know you don't offer any complimentary items but water and coffee will not break the bank !!

My mother was HARASSED AND ACCOSTED by the gate agent for her bag. I pre purchased the bag fee and the gate agent made my 78 year old mother board, deplane, re pay for her bag fee and board again. The gate agent made my mother pick up her own bag and REFUSED to help her, she is an older woman who wasn’t bothering anyone on a flight that had maybe 30’total passengers. I am going to sue this airlines for their HORRIBLE customer service and treatment of my mother, and all this occurred the day after Mother’s Day!!!

Horrible, first flight delayed. They switched my connecting flight while I was en route and even though I was originally supposed to be on the flight going back home to boston, refused to let me board and told me I would have to wait for next flight that was 14 hours later. Ended up renting a car and driving 6.5 hours back home. Still getting messages about flight and it is now showing that the other flight they put me on is now canceled and I would have to wait 24 hours for the next one. I will never book with spirit again

They stuck us with multiple extra fees. I will never fly spirit again

Overall it was a miserable experience... I will never fly spirit for more than a 3 hour flight or overnight.

what I like about Spirit is that the pilot and crew are good communicators. The plane itself - well, its a budget airline and you get what is expected, But I generally just feel safer, somehow, when I know more about what is going on - and Spirit has always done a good job of telling me what is going on: why the delay, why the turbulence, why this and that... and that means a lot to me.

I paid just under 200 for flight and luggage, then paid 200 to change the flight, then paid 100 for a carry on. Then the cancelled the flight. Of the 500 I spent they refunded 250. I bought a delta flight for 270 never flew with spirit, but spirit kept 250, not even refunding the 100 for the carry on though they cancelled the flight (for weather on a day with only a slight rain ).

Book cheap flights from John Wayne (Santa Ana) to Missouri

Recent round-trip flight deals

9/11Wed
1 stopFrontier
9h 46mSNA-STL
9/14Sat
1 stopFrontier
26h 04mSTL-SNA
$150
9/25Wed
1 stopFrontier
9h 46mSNA-STL
10/2Wed
1 stopFrontier
26h 04mSTL-SNA
$168
8/20Tue
1 stopUnited Airlines
8h 56mSNA-SGF
8/23Fri
1 stopUnited Airlines
9h 25mSGF-SNA
$318
9/10Tue
1 stopUnited Airlines
7h 48mSNA-SGF
9/17Tue
2 stopsUnited Airlines
8h 32mSGF-SNA
$323
8/28Wed
2 stopsAmerican Airlines
8h 12mSNA-MCI
9/2Mon
1 stopAmerican Airlines
6h 27mMCI-SNA
$331
7/14Sun
1 stopDelta
7h 36mSNA-MCI
7/20Sat
1 stopDelta
5h 20mMCI-SNA
$371
9/12Thu
1 stopDelta
5h 26mSNA-STL
9/17Tue
1 stopDelta
6h 58mSTL-SNA
$386
9/24Tue
2 stopsAmerican Airlines
7h 30mSNA-STL
9/30Mon
1 stopAmerican Airlines
9h 38mSTL-SNA
$391
9/13Fri
2 stopsAlaska Airlines
14h 59mSNA-STL
9/16Mon
2 stopsAlaska Airlines
15h 57mSTL-SNA
$424
9/26Thu
2 stopsAlaska Airlines
15h 14mSNA-MCI
9/30Mon
1 stopAlaska Airlines
8h 30mMCI-SNA
$479

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Recent one-way flight deals

9/2Mon
1 stopFrontier
23h 26mSNA-STL
$72
8/20Tue
1 stopFrontier
12h 25mSNA-STL
$76
10/16Wed
1 stopAmerican Airlines
5h 19mSNA-MCI
$163
7/10Wed
1 stopUnited Airlines
5h 55mSNA-SGF
$173
10/16Wed
2 stopsAlaska Airlines
10h 44mSNA-MCI
$186
8/11Sun
1 stopDelta
7h 44mSNA-STL
$213
7/1Mon
1 stopDelta
5h 56mSNA-STL
$224
7/5Fri
2 stopsAmerican Airlines
8h 07mSNA-STL
$229
7/10Wed
2 stopsAlaska Airlines
12h 18mSNA-STL
$237
6/19Wed
1 stopUnited Airlines
18h 35mSNA-STL
$337

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Last minute flights from Santa Ana to Missouri

Last minute flight, train and bus deals

6/13Thu
multi-stopFrontier
16h 42mSNA-STL
6/17Mon
multi-stopFrontier
25h 44mSTL-SNA
$366
6/12Wed
multi-stopUnited Airlines
6h 07mSNA-SGF
6/22Sat
multi-stopUnited Airlines
5h 21mSGF-SNA
$373
6/12Wed
multi-stopAmerican Airlines
5h 10mSNA-SGF
6/20Thu
multi-stopAmerican Airlines
6h 55mSGF-SNA
$398
6/12Wed
multi-stopAmerican Airlines
5h 10mSNA-SGF
6/22Sat
multi-stopAmerican Airlines
8h 14mSGF-SNA
$403
6/12Wed
multi-stopAmerican Airlines
7h 30mSNA-SGF
6/22Sat
multi-stopAmerican Airlines
8h 14mSGF-SNA
$408
6/13Thu
multi-stopSpirit Airlines
23h 14mSNA-MCI
6/17Mon
multi-stopSpirit Airlines
5h 00mMCI-SNA
$531
6/13Thu
multi-stopSpirit Airlines
9h 19mSNA-MCI
6/16Sun
multi-stopSpirit Airlines
4h 59mMCI-SNA
$555
6/15Sat
multi-stopAlaska Airlines
7h 18mSNA-MCI
6/16Sun
multi-stopAlaska Airlines
7h 44mMCI-SNA
$926
6/15Sat
multi-stopDelta
7h 40mSNA-MCI
6/21Fri
multi-stopDelta
9h 07mMCI-SNA
$1,030
6/12Wed
multi-stopDelta
12h 30mSNA-STL
6/16Sun
multi-stopDelta
10h 58mSTL-SNA
$1,225

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Santa Ana - Missouri Flights

Departure:

John Wayne (Santa Ana) (SNA)United States

Return flight deals:

Missouri - John Wayne (Santa Ana)

Cabin classes: