$100 Find Cheap Flights from John Wayne (Santa Ana) to Missouri - Compare and Save

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1 adult, Economy, 0 bags

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Cheap Flights from Santa Ana to Missouri

Cheapest round-trip prices found by our users on KAYAK in the last 5 days
St. Louis
St. Louis1 stop$272
Springfield
Springfield1 stop$359
Columbia
Columbia1 stop$383
Joplin
Joplin1 stop$444
St. Louis
St. Louis1 stop$272
Springfield
Springfield1 stop$359
Columbia
Columbia1 stop$383
Joplin
Joplin1 stop$444
Booking Insights

KAYAK's insights & trends for Santa Ana to Missouri flights

Get data-powered insights and trends into flights from Santa Ana to Missouri to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santa Ana, California to Missouri?

Flight prices are below average for this route right now.

Flights to Missouri from Santa Ana, California usually cost between $408 and $572 in October.
The lowest price found in the past 5 days was $272 on Frontier (Oct 26-Oct 29).

What is the cheapest month to fly from John Wayne (Santa Ana) to Missouri?

The cheapest month for flights from John Wayne (Santa Ana) to Missouri is October, when tickets cost $384 (return) on average. On the other hand, the most expensive months are March and July, when the average cost of round-trip tickets is $577 and $557 respectively.

Good to know

Low season

August

Cheapest flight

$100
Best time to beat the crowds but there is an average 11% increase in price.
Most popular time to fly and prices are also 6% lower on average.
Flight from John Wayne (Santa Ana) to Kansas City

FAQs - booking Missouri flights

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Missouri?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Missouri.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Missouri?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from John Wayne (Santa Ana) to Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Missouri?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from John Wayne (Santa Ana) to Missouri with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Missouri?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from John Wayne (Santa Ana) to Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Santa Ana to Missouri

 
Need help choosing which airline to fly with from Santa Ana to Missouri? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
SouthwestOverall score based on 4190 reviews
7.0Food
8.1Boarding
8.0Comfort
7.5Entertainment
8.6Crew
Airline reviews

Just crazy with times being pushed and pushed and pushed and gate crew at Philly super rude and unprofessional with many under stress with delays.

2.0 MediocreHans, Aug 2026
Read more Southwest reviews

Just crazy with times being pushed and pushed and pushed and gate crew at Philly super rude and unprofessional with many under stress with delays.

Great job! My family doesnt fly often but we felt safe 100%

Communication about the delayed flight was poor. We were told to move gates three times but that was bad information. We went from gate 128 to gate 126 and then to gate 123 and back to gate 126. Communication about the delay was bad. Ended up being 1 1/2 hour late getting home.

I have roller bag with food and medication told me I couldn't bring on my 2nd flight today. 15 years flying with SW never an issue with that bag.

I have not flown Southwest in awhile and had a very pleasant experience. From ticketing to boarding to the flight. The flight left on time and landed ahead of schedule. It won't be so long next time!!

Everything went smoothly and we even arrived a little bit early.

Great flight, 47 passengers on a 180 seat plane. Stewardess was pleasant and cheerful.

The 700 model seating is too tight both seat size & leg room

Two hour delay including one of them on the tarmac second year in a row we’ve had a bad experience. Sad that Southwest is no longer a bargain and has failed to keep up the customer service they were once so famous for.

They should not let people take up more than their seat space. Need to buy another ticket if they overflow into someone else’s space. Or you should make your seats larger to accommodate larger folks.

Flight team was great and we even arrived ahead of plan!

Flight late, the waited for a long time for “personal” to arrive at gate to dock the plane in Rochester. So annoying. This flight was expected, why aren’t personel available for the jet bridge?

We departed early and made up time in the air allowing us to arrive 30 minutes early. Capt was incredibly genuine and thanked every passenger for flying with Delta. Completely humble and professional!

The boarding process needs to be refined. Sometimes the gate crew calls out the zones and then flip to showing the.zones boarding on the gate monitor display. So, unless you are huddled around the gate lanes watching the monitor, you could miss your boarding zone. Suggest the zones be announced each time a new zone is allowed to board.

Flight delayed for two and half hours and then canceled altogether due to mechanical issues. No mechanic onsite to fix so had to send one from LAX.

This route with Delta always has delays or is cancelled. Aircrafts seem smaller and older. I fly Delta quite a bit - haven’t had issues with the international flights. But this route has always been the troublesome one

On 2 different flights the wifi was horrible and there was no drink or snack service.

There was no FREE wi-fi nor entertainment screens at all.

Great, on time departure, friendly and accommodating crew, great leg room, Smith flight

Flight and seats were great. Food service was average at best. The real main problem we had is that we got cheeseburgers for the kids but the plates was extremely hot. Like ridiculously hot and the stewardess never said anything. Luckily or unluckily my wife touched the plate and was able to deal with it before the kids got burned.

Flight was delayed “due to earlier delays of that plane”, so we were nearly three hours late.

Crew was amazing, takeoff wonderful. The bathroom was disgusting from before takeoff the odor made the flight uncomfortable as you could smell the bathroom from the center of the plane where we were sitting. Smelled like raw sewage. My daughter was throwing up as we landed due to the smell and horrible turbulence as we approached Newark.

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

Airport terminal was outdated, flight was on a small jet with no wifi

Essy to get on. The hostess gave very little pop, the plane was late getting in, and we are still waiting for our bags. This sucks. :/

Lately I like the planes have been exceptionally filthy. There’s lines of dust and dirt all across the ceiling in the vents, and the cracks in between the seats are literally full of food. It’s definitely not the quality of service that I was used to with United. I’m also very disappointed with the Wi-Fi! All I wanna do is knock out a few work jobs while I’m trapped in my seat And it spools so bad. They did provide me with a refund, but the process of getting that refund is so complicated. It’s unfortunate.

Not a great experience. We paid for the upgrade for premium economy seats and seated ourselves in very comfortable seats. Someone came along with the same seat on their boarding pass. The aircraft had been changed and as a result we were booted out and sent further back to small uncomfortable seats. After complaining we were moved to emergency row seats, which gave us more leg room but the seats don’t recline. For people in our 70’s we found having to sit upright from California to NJ very uncomfortable. Not sure why they chose to move senior citizens instead of the two people that were allowed to take the more comfortable seats. Not happy.

Very poor the plane itself was really old, slight smell that couldn’t be named. I didn’t even get a boarding pass UNTIL AFTER clearing security! Even then, they said when I get to my connected flight I’ll get my 2nd boarding pass there! A bit ridiculous!

Due to one crew member not showing up to work, our flight was significantly delayed causing us to miss our connecting flight in Houston to Mississippi causing us to be delayed by more than 6 hours and missing our event all together. Very disappointing. All because ONE crew member called in sick. United did grant us a $15 meal voucher, which was a small but appreciated concession that I wasn’t able to use because I ordered my lunch and paid for it before applying the concession, and the staff said it was too late to use it. Ugh! We also had a TWO delay coming back from Mississippi, but that was on American Airlines and it was due to weather, so not their fault. Anyway, not at all impressed with United’s handling of our flight and the HUGE disappointment of missing our important family event for our 90 year old mother. All that money and all that stress and emotions for nothing. Having to wait the hour to bring an employee from LAX seemed like something that should not have happened. Why don’t you have a local back-up? Santa Ana is not a little airport in a rural area.

the head jack on my seat didn't work and the power outlet didn't work for my seat

As with most flights these days it was delayed by about 30 min.

The WiFi didn’t work entire flight, couldn’t watch a movie. The recline button didn’t work

Flight was 3 hours delayed. They gave our plan to two other routes. Need to knock that off.

Small plane, poor meal choices for first class, bad terminal and boarding experience at LAX

Our flight was 1.5 hours delayed. There was no weather for the inbound flight, so I don't understand why. This meant a VERY late arrival and only a quick nap before my morning flight.

The flight encountered a delay exceeding 4 hours. The food voucher issued was valued at $12, insufficient to cover our meal expenses. Consequently, I was unable to take my medication, leading to a drop in blood sugar levels and exacerbating my anxiety.

Flights were on time. That's the main consideration since I had to change planes. The entertainment was whatever you bring with you and the food (in Economy) is non-existant. Neither of those was a surprise.

The gate crew did try to help, however they lacked the information as to whether the flight will operate or not. Being delayed 6 hours and in a limbo on whether the flight will operate or not is not fun. The airline having staffing issues is not encouraging at all.

Flight was delayed and missed connecting flight. Did not give warning about delay until we showed up at the airport. Not good.

I love to be able to connect my own devices to the entertainment system. It works great!

More options for your flight from Santa Ana to Missouri

Complete your trip to Missouri with a hotel stay or car rental