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$42 Find cheap flights from South Carolina to Chicago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Chicago departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Tue 6/18
Tue 6/25

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In the last 7 days travelers have searched 41,904,688 times on KAYAK, and here is why:

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Good to know

Low season

January

High season

June

Cheapest flight

$42
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly with an average 11% increase in price.
Flight from Myrtle Beach to Chicago O'Hare Airport

FAQs for booking flights from South Carolina to Chicago

  • How does KAYAK find such low prices on flights from South Carolina to Chicago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Chicago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from South Carolina to Chicago?

Find which airlines fly direct from South Carolina to Chicago, which days they fly and book direct flights.

Nonstop departures

South Carolina to Chicago

Monday

ANA, Aer Lingus, Aeromexico, +80 more

ANA, Aer Lingus, +81 more

Tuesday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

Wednesday

ANA, Aer Lingus, Aeromexico, +79 more

ANA, Aer Lingus, +80 more

Thursday

ANA, Aer Lingus, Aeromexico, +78 more

ANA, Aer Lingus, +79 more

Friday

ANA, Aer Lingus, Aerolineas Argentinas, +81 more

ANA, Aer Lingus, +82 more

Saturday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

Sunday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

See more direct flights

Nonstop returns

Chicago to South Carolina

Monday

ANA, Aer Lingus, Aeromexico, +80 more

ANA, Aer Lingus, +81 more

Tuesday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

Wednesday

ANA, Aer Lingus, Aeromexico, +79 more

ANA, Aer Lingus, +80 more

Thursday

ANA, Aer Lingus, Aeromexico, +78 more

ANA, Aer Lingus, +79 more

Friday

ANA, Aer Lingus, Aerolineas Argentinas, +81 more

ANA, Aer Lingus, +82 more

Saturday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

Sunday

ANA, Aer Lingus, Aerolineas Argentinas, +79 more

ANA, Aer Lingus, +80 more

See more direct flights
See more direct flights

Book cheap flights from South Carolina to Chicago

Recent round-trip flight deals

5/29Wed
nonstopFrontier
2h 08mCLT-ORD
6/3Mon
nonstopFrontier
2h 00mORD-CLT
$62
5/29Wed
1 stopSpirit Airlines
8h 20mCLT-ORD
6/5Wed
1 stopSpirit Airlines
9h 40mORD-CLT
$65
5/29Wed
1 stop
5h 29mCLT-ORD
6/3Mon
nonstop
2h 00mORD-CLT
$66
6/5Wed
nonstopSpirit Airlines
2h 00mCLT-ORD
6/10Mon
nonstopSpirit Airlines
2h 04mORD-CLT
$67
9/6Fri
nonstop
2h 06mCLT-ORD
9/9Mon
nonstop
2h 01mORD-CLT
$79
7/6Sat
1 stopDelta
4h 01mCLT-MDW
7/20Sat
1 stopDelta
4h 27mMDW-CLT
$175
5/29Wed
nonstopAmerican Airlines
2h 13mCLT-ORD
6/1Sat
nonstopAmerican Airlines
1h 59mORD-CLT
$188
6/1Sat
nonstopAmerican Airlines
2h 13mCLT-ORD
6/9Sun
nonstopAmerican Airlines
1h 57mORD-CLT
$202
6/20Thu
1 stopSun Country Air
7h 27mSAV-ORD
6/23Sun
1 stopSun Country Air
5h 59mORD-SAV
$202
6/28Fri
1 stopDelta
5h 17mCLT-MDW
6/30Sun
1 stopDelta
6h 25mMDW-CLT
$215

Search by stops

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Recent one-way flight deals

5/28Tue
nonstopSpirit Airlines
2h 26mMYR-ORD
$42
7/20Sat
nonstopSpirit Airlines
2h 14mCLT-ORD
$45
6/14Fri
nonstopFrontier
2h 10mCLT-ORD
$46
6/1Sat
1 stopFrontier
5h 37mCLT-MDW
$49
7/6Sat
nonstopAmerican Airlines
2h 14mCLT-ORD
$77
7/18Thu
1 stopSun Country Air
13h 10mCLT-ORD
$85
7/8Mon
1 stopSun Country Air
6h 40mCLT-ORD
$86
7/6Sat
1 stopDelta
3h 49mCLT-MDW
$87
7/6Sat
1 stopDelta
6h 11mCLT-ORD
$87
5/25Sat
nonstopAmerican Airlines
2h 13mCLT-ORD
$93

Search by stops

Search by airline

Search by price

Last minute flights from South Carolina to Chicago

Last minute flight, train and bus deals

5/22Wed
nonstopFrontier
2h 08mCLT-ORD
5/29Wed
nonstopFrontier
2h 00mORD-CLT
$104
5/22Wed
nonstop
2h 08mCLT-ORD
5/30Thu
nonstop
2h 01mORD-CLT
$110
5/22Wed
nonstopFrontier
2h 08mCLT-ORD
5/31Fri
nonstopFrontier
2h 00mORD-CLT
$111
5/22Wed
nonstop
2h 08mCLT-ORD
5/29Wed
multi-stop
10h 38mORD-CLT
$112
5/22Wed
nonstop
2h 08mCLT-ORD
5/28Tue
multi-stop
12h 18mORD-CLT
$114
5/23Thu
nonstopSpirit Airlines
2h 15mCLT-ORD
5/28Tue
multi-stopSpirit Airlines
12h 18mORD-CLT
$116
5/23Thu
nonstopSpirit Airlines
2h 15mCLT-ORD
5/29Wed
multi-stopSpirit Airlines
11h 44mORD-CLT
$117
5/24Fri
multi-stopDelta
4h 06mCLT-MDW
5/25Sat
multi-stopDelta
7h 11mMDW-CLT
$295
5/24Fri
multi-stopDelta
4h 06mCLT-MDW
5/27Mon
multi-stopDelta
6h 24mMDW-CLT
$315
5/23Thu
multi-stopSun Country Air
6h 18mSAV-ORD
5/26Sun
multi-stopSun Country Air
25h 34mORD-SAV
$328

Search by stops

Search by airline

Search by price

Flights to Chicago

Return flight deals:

Chicago - South Carolina

Cabin classes:

$595
$569
$704
$84