How does KAYAK find such low prices on flights from South Carolina to Chicago?

KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.

How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?

KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

What is the Hacker Fare option on flights from South Carolina to Chicago?

Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.

What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?

Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

$89 CHEAP FLIGHTS from South Carolina to Chicago

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Cheap Flights from South Carolina to Chicago

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Direct

Recent round-trip flight deals from South Carolina to Chicago

Wed, Sep 9 - Wed, Sep 16

12:23 pm - 2:45 pmSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

27h 22m1 stop Fort Lauderdale

7:11 am - 1:00 pmORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

28h 49m1 stop Fort Lauderdale

$183Multiple Airlines

Wed, Sep 23 - Wed, Sep 30

12:23 pm - 2:45 pmSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

27h 22m1 stop Fort Lauderdale

7:11 am - 4:15 pmORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

8h 04m1 stop Fort Lauderdale

$184Multiple Airlines

Sat, Sep 5 - Mon, Sep 7

5:00 pm - 6:38 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 38mnonstop

8:15 am - 11:34 amORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 19mnonstop

$197American Airlines

Tue, Sep 15 - Tue, Sep 22

6:58 pm - 11:59 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

6h 01m1 stop Atlanta Hartsfield-Jackson

6:25 pm - 11:28 pmORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

4h 03m1 stop Atlanta Hartsfield-Jackson

$217Delta

Sat, Dec 5 - Tue, Dec 15

4:00 pm - 8:48 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

5h 48m1 stop Atlanta Hartsfield-Jackson

8:04 am - 1:33 pmORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

4h 29m1 stop Atlanta Hartsfield-Jackson

$217Delta

Thu, Oct 1 - Tue, Oct 6

7:46 pm - 9:30 pmCHS Charleston-ORD Chicago O'Hare Intl

2h 44mnonstop

11:45 am - 3:02 pmORD Chicago O'Hare Intl-CHS Charleston

2h 17mnonstop

$237American Airlines

Wed, Sep 16 - Wed, Sep 23

6:30 am - 8:00 amCHS Charleston-ORD Chicago O'Hare Intl

2h 30mnonstop

10:33 am - 1:58 pmORD Chicago O'Hare Intl-CHS Charleston

2h 25mnonstop

$237United Airlines

Wed, Sep 23 - Sat, Sep 26

4:58 pm - 6:30 pmCHS Charleston-ORD Chicago O'Hare Intl

2h 32mnonstop

10:39 am - 2:04 pmORD Chicago O'Hare Intl-CHS Charleston

2h 25mnonstop

$237United Airlines

Tue, Nov 10 - Wed, Nov 11

8:00 am - 9:15 amCHS Charleston-MDW Chicago Midway

2h 15mnonstop

1:25 pm - 4:30 pmMDW Chicago Midway-CHS Charleston

2h 05mnonstop

$237Southwest

Thu, Oct 1 - Tue, Oct 6

7:15 pm - 8:25 pmCHS Charleston-MDW Chicago Midway

2h 10mnonstop

1:30 pm - 4:40 pmMDW Chicago Midway-CHS Charleston

2h 10mnonstop

$237Southwest

Recent last minute flight deals from South Carolina to Chicago

Tue, Aug 25 - Tue, Sep 15

8:56 am - 11:08 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

15h 12m1 stop Orlando

3:50 pm - 8:35 amORD Chicago O'Hare Intl-CLT Charlotte Douglas

15h 45m1 stop Orlando

$259Frontier

Tue, Aug 25 - Tue, Sep 15

9:52 pm - 11:08 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

26h 16m1 stop Orlando

3:50 pm - 3:16 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

22h 26m1 stop Orlando

$260Frontier

Mon, Aug 24 - Thu, Aug 27

6:25 pm - 10:50 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

17h 25m1 stop Owensboro Daviess County

11:30 am - 5:00 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

4h 30m1 stop Owensboro Daviess County

$274Contour

Mon, Aug 24 - Mon, Aug 31

6:25 pm - 10:50 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

17h 25m1 stop Owensboro Daviess County

11:30 am - 5:00 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

4h 30m1 stop Owensboro Daviess County

$274Contour

Sat, Aug 22 - Sat, Aug 29

6:00 am - 10:10 amGSP Greenville-MDW Chicago Midway

5h 10m1 stop Atlanta Hartsfield-Jackson

6:11 am - 12:41 pmMDW Chicago Midway-GSP Greenville

5h 30m1 stop Atlanta Hartsfield-Jackson

$361Delta

Tue, Aug 25 - Tue, Sep 15

6:35 pm - 7:35 pmCLT Charlotte Douglas-MDW Chicago Midway

2h 00mnonstop

8:45 am - 11:55 amMDW Chicago Midway-CLT Charlotte Douglas

2h 10mnonstop

$363Southwest

Sat, Aug 22 - Tue, Aug 25

2:28 pm - 3:30 pmGSP Greenville-ORD Chicago O'Hare Intl

2h 02mnonstop

6:30 am - 9:36 amORD Chicago O'Hare Intl-GSP Greenville

2h 06mnonstop

$363United Airlines

Tue, Aug 25 - Tue, Sep 15

8:05 am - 9:23 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 18mnonstop

1:55 pm - 5:17 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 22mnonstop

$363United Airlines

Sat, Aug 22 - Sat, Aug 29

3:30 pm - 7:20 pmGSP Greenville-MDW Chicago Midway

4h 50m1 stop Nashville Intl

11:45 am - 7:00 pmMDW Chicago Midway-GSP Greenville

6h 15m2 stops Grand Rapids Gerald R. Ford Intl Baltimore/Washington

$366Southwest

Sat, Aug 22 - Wed, Aug 26

12:39 pm - 4:17 pmGSP Greenville-ORD Chicago O'Hare Intl

4h 38m1 stop Detroit Metropolitan Wayne County

1:50 pm - 8:32 pmORD Chicago O'Hare Intl-GSP Greenville

5h 42m1 stop Atlanta Hartsfield-Jackson

$383Delta

Recent direct flight deals from South Carolina to Chicago

Sat, Sep 5 - Mon, Sep 7

5:00 pm - 6:38 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 38mnonstop

8:15 am - 11:34 amORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 19mnonstop

$197American Airlines

Tue, Nov 10 - Wed, Nov 11

8:00 am - 9:15 amCHS Charleston-MDW Chicago Midway

2h 15mnonstop

1:25 pm - 4:30 pmMDW Chicago Midway-CHS Charleston

2h 05mnonstop

$237Southwest

Mon, Nov 2 - Thu, Nov 5

6:55 pm - 8:32 pmSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

2h 37mnonstop

6:59 am - 10:22 amORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

2h 23mnonstop

$237United Airlines

Mon, Oct 19 - Wed, Oct 21

8:53 am - 10:29 amSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

2h 36mnonstop

7:30 am - 11:00 amORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

2h 30mnonstop

$237United Airlines

Wed, Oct 14 - Sat, Oct 17

1:47 pm - 3:29 pmSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

2h 42mnonstop

9:45 am - 1:16 pmORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

2h 31mnonstop

$237American Airlines

Thu, Oct 1 - Sat, Oct 3

11:56 am - 1:33 pmSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

2h 37mnonstop

8:00 am - 11:26 amORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

2h 26mnonstop

$237American Airlines

Thu, Oct 1 - Tue, Oct 6

7:15 pm - 8:25 pmCHS Charleston-MDW Chicago Midway

2h 10mnonstop

1:30 pm - 4:40 pmMDW Chicago Midway-CHS Charleston

2h 10mnonstop

$237Southwest

Tue, Nov 10 - Sat, Nov 14

9:07 am - 10:41 amSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

2h 34mnonstop

7:14 am - 10:38 amORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

2h 24mnonstop

$237United Airlines

Wed, Oct 21 - Wed, Oct 28

7:15 am - 8:25 amCHS Charleston-MDW Chicago Midway

2h 10mnonstop

1:30 pm - 4:40 pmMDW Chicago Midway-CHS Charleston

2h 10mnonstop

$237Southwest

Wed, Sep 23 - Wed, Sep 30

11:56 am - 1:33 pmSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

2h 37mnonstop

8:00 am - 11:26 amORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

2h 26mnonstop

$237American Airlines

Useful Info

Low season	February
High season	October
Cheapest flight	$89

Best time to beat the crowds with an average 8% drop in price.

Most popular time to fly and prices are also 5% lower on average.

Flight from Myrtle Beach to Chicago O'Hare Airport

Verified travelerFlew with American Airlines-Apr 2026

Chicago has a enormous airport so be ready to walk and transfer to international flights by train via terminal

YesicaFlew with United Airlines-Feb 2026

Utilize the mobile app of your airline it will give you all the updates and information you need

EllenFlew with United Airlines-May 2024

Greenville airport is small, getting through security won't take too long (particularly if you have Precheck). Be prepared to walk for 10-15 minutes from your arrival gate in O'Hare to your next departure gate, if you have one. Sometimes those gates are really close together, but my experience is that they are typically farther apart and require a solid walk.

How does KAYAK find such low prices on flights from South Carolina to Chicago?
KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.
How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?
KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.
What is the Hacker Fare option on flights from South Carolina to Chicago?
Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.
What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?
Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Merrillville

Saint Joseph

Hammond

Portage

Lansing

Valparaiso

Chesterton

Munster

Schererville

Porter

Monticello

Saint John

Griffith

Everything you need to know for your flight to Chicago

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Return flight deals

Cabin class types available on flights to South Carolina

First Class flights to Chicagofrom $497

Business Class flights to Chicagofrom $584

Premium Economy Class flights to Chicagofrom $643

Economy Class flights to Chicagofrom $237

$89 Find Cheap Flights from South Carolina to Chicago - Compare and Save

Cheap Flights from South Carolina to Chicago

Recent round-trip flight deals from South Carolina to Chicago

Recent one-way flight deals from South Carolina to Chicago

Recent last minute flight deals from South Carolina to Chicago

Recent direct flight deals from South Carolina to Chicago

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High season

Cheapest flight

Flights from South Carolina to Chicago: the best tips from KAYAK users

FAQs for booking flights from South Carolina to Chicago

Traveling to a place near Chicago?

Everything you need to know for your flight to Chicago

Cabin class types available on flights to South Carolina

Complete your trip to Chicago with a hotel stay or car rental

Find direct flights for Chicago

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Choose which airport to fly into in Chicago

Find deals for your return flight