How does KAYAK find such low prices on flights from South Carolina to Chicago?

KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.

How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?

KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

What is the Hacker Fare option on flights from South Carolina to Chicago?

Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.

What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?

Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

$93 CHEAP FLIGHTS from South Carolina to Chicago

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Cheap Flights from South Carolina to Chicago

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Direct

Recent round-trip flight deals from South Carolina to Chicago

Tue, Oct 27 - Thu, Oct 29

6:00 am - 10:07 amCHS Charleston-ORD Chicago O'Hare Intl

5h 07m1 stop Washington, D.C. Reagan-National

8:05 am - 3:44 pmORD Chicago O'Hare Intl-CHS Charleston

6h 39m1 stop Charlotte Douglas

$254American Airlines

Sat, Oct 31 - Mon, Nov 2

8:50 am - 3:00 pmCHS Charleston-ORD Chicago O'Hare Intl

7h 10m1 stop Atlanta Hartsfield-Jackson

5:27 am - 11:07 amORD Chicago O'Hare Intl-CHS Charleston

4h 40m1 stop Atlanta Hartsfield-Jackson

$254Delta

Wed, Dec 2 - Sat, Dec 5

5:15 pm - 9:30 pmCHS Charleston-MDW Chicago Midway

5h 15m1 stop Baltimore/Washington

7:50 am - 8:05 pmMDW Chicago Midway-CHS Charleston

11h 15m2 stops Atlanta Hartsfield-Jackson Baltimore/Washington

$258Southwest

Mon, Nov 9 - Fri, Nov 13

7:10 pm - 8:25 pmCHS Charleston-MDW Chicago Midway

2h 15mnonstop

5:20 pm - 12:35 amMDW Chicago Midway-CHS Charleston

6h 15m1 stop Houston Hobby

$258Southwest

Tue, Nov 10 - Thu, Nov 12

2:06 pm - 6:33 pmCHS Charleston-ORD Chicago O'Hare Intl

5h 27m1 stop Washington, D.C. Reagan-National

8:59 pm - 12:17 amORD Chicago O'Hare Intl-CHS Charleston

2h 18mnonstop

$258American Airlines

Thu, Nov 12 - Mon, Nov 16

6:45 am - 9:14 amCHS Charleston-ORD Chicago O'Hare Intl

27h 29m2 stops Columbus Atlanta Hartsfield-Jackson

9:51 am - 8:38 amORD Chicago O'Hare Intl-CHS Charleston

21h 47m1 stop Orlando

$259Multiple Airlines

Mon, Nov 9 - Fri, Nov 13

7:00 pm - 8:40 pmCHS Charleston-ORD Chicago O'Hare Intl

2h 40mnonstop

7:47 am - 11:21 amORD Chicago O'Hare Intl-CHS Charleston

2h 34mnonstop

$261United Airlines

Fri, Dec 4 - Mon, Dec 7

6:00 am - 7:37 amCHS Charleston-ORD Chicago O'Hare Intl

2h 37mnonstop

5:59 pm - 9:21 pmORD Chicago O'Hare Intl-CHS Charleston

2h 22mnonstop

$261United Airlines

Fri, Nov 13 - Mon, Nov 16

4:57 pm - 3:37 pmCHS Charleston-ORD Chicago O'Hare Intl

23h 40m1 stop Fort Lauderdale

9:51 am - 8:38 amORD Chicago O'Hare Intl-CHS Charleston

21h 47m1 stop Orlando

$265Multiple Airlines

Wed, Jan 6 - Fri, Jan 8

1:00 pm - 6:37 pmCHS Charleston-MDW Chicago Midway

6h 37m1 stop Detroit Metropolitan Wayne County

5:25 pm - 11:56 pmMDW Chicago Midway-CHS Charleston

5h 31m1 stop Atlanta Hartsfield-Jackson

$267Delta

Recent last minute flight deals from South Carolina to Chicago

Tue, Oct 13 - Tue, Oct 20

4:03 pm - 3:30 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

24h 27m1 stop Fort Lauderdale

8:04 am - 9:13 amORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

24h 09m1 stop Fort Lauderdale

$349Multiple Airlines

Tue, Oct 13 - Tue, Oct 20

4:03 pm - 11:32 amMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

20h 29m2 stops Fort Lauderdale Atlanta Hartsfield-Jackson

8:04 am - 9:13 amORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

24h 09m1 stop Fort Lauderdale

$350Multiple Airlines

Tue, Oct 13 - Tue, Oct 20

6:01 am - 7:22 amGSP Greenville-ORD Chicago O'Hare Intl

2h 21mnonstop

3:06 pm - 6:08 pmORD Chicago O'Hare Intl-GSP Greenville

2h 02mnonstop

$381American Airlines

Tue, Oct 13 - Tue, Oct 20

7:25 pm - 11:00 pmGSP Greenville-ORD Chicago O'Hare Intl

4h 35m1 stop Charlotte Douglas

7:54 pm - 11:00 pmORD Chicago O'Hare Intl-GSP Greenville

2h 06mnonstop

$391American Airlines

Tue, Oct 13 - Tue, Oct 20

2:51 pm - 6:41 pmGSP Greenville-ORD Chicago O'Hare Intl

4h 50m1 stop Washington, D.C. Dulles Intl

8:50 am - 2:16 pmORD Chicago O'Hare Intl-GSP Greenville

4h 26m1 stop Washington, D.C. Dulles Intl

$401United Airlines

Sat, Oct 10 - Mon, Oct 12

6:20 am - 7:29 amGSP Greenville-ORD Chicago O'Hare Intl

2h 09mnonstop

6:17 pm - 9:17 pmORD Chicago O'Hare Intl-GSP Greenville

2h 00mnonstop

$416United Airlines

Sat, Oct 10 - Sun, Oct 11

7:20 am - 12:47 pmGSP Greenville-MDW Chicago Midway

6h 27m1 stop Detroit Metropolitan Wayne County

6:04 am - 11:00 amMDW Chicago Midway-GSP Greenville

3h 56m1 stop Atlanta Hartsfield-Jackson

$436Delta

Sat, Oct 10 - Sun, Oct 11

2:00 pm - 7:11 pmGSP Greenville-ORD Chicago O'Hare Intl

6h 11m1 stop Atlanta Hartsfield-Jackson

6:30 am - 1:00 pmORD Chicago O'Hare Intl-GSP Greenville

5h 30m1 stop Atlanta Hartsfield-Jackson

$436Delta

Tue, Oct 13 - Wed, Oct 14

7:15 am - 8:25 amCHS Charleston-MDW Chicago Midway

2h 10mnonstop

1:30 pm - 4:40 pmMDW Chicago Midway-CHS Charleston

2h 10mnonstop

$471Southwest

Tue, Oct 13 - Tue, Oct 20

7:15 am - 8:25 amCHS Charleston-MDW Chicago Midway

2h 10mnonstop

1:30 pm - 4:40 pmMDW Chicago Midway-CHS Charleston

2h 10mnonstop

$471Southwest

Useful Info

Low season	February
High season	July
Cheapest flight	$93

Best time to beat the crowds with an average 10% drop in price.

Most popular time to fly with an average 16% increase in price.

Flight from Charleston to Chicago O'Hare Airport

Verified travelerFlew with American Airlines-Apr 2026

Chicago has a enormous airport so be ready to walk and transfer to international flights by train via terminal

YesicaFlew with United Airlines-Feb 2026

Utilize the mobile app of your airline it will give you all the updates and information you need

EllenFlew with United Airlines-May 2024

Greenville airport is small, getting through security won't take too long (particularly if you have Precheck). Be prepared to walk for 10-15 minutes from your arrival gate in O'Hare to your next departure gate, if you have one. Sometimes those gates are really close together, but my experience is that they are typically farther apart and require a solid walk.

How does KAYAK find such low prices on flights from South Carolina to Chicago?
KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.
How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?
KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.
What is the Hacker Fare option on flights from South Carolina to Chicago?
Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.
What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?
Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Merrillville

Hammond

Saint Joseph

Portage

Lansing

Valparaiso

Chesterton

Schererville

Munster

Porter

Monticello

Saint John

Griffith

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$93 Find Cheap Flights from South Carolina to Chicago - Compare and Save

Cheap Flights from South Carolina to Chicago

Recent round-trip flight deals from South Carolina to Chicago

Recent one-way flight deals from South Carolina to Chicago

Recent last minute flight deals from South Carolina to Chicago

Recent direct flight deals from South Carolina to Chicago

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Flights from South Carolina to Chicago: the best tips from KAYAK users

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