How does KAYAK find such low prices on flights from South Carolina to Chicago?

KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.

How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?

KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

What is the Hacker Fare option on flights from South Carolina to Chicago?

Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.

What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?

Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

$120 CHEAP FLIGHTS from South Carolina to Chicago

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Cheap Flights from South Carolina to Chicago

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Direct

Recent round-trip flight deals from South Carolina to Chicago

Wed, Oct 7 - Wed, Oct 14

12:23 pm - 3:30 pmSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

28h 07m1 stop Fort Lauderdale

8:04 am - 4:20 pmORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

7h 16m1 stop Fort Lauderdale

$235Multiple Airlines

Thu, Oct 29 - Sat, Oct 31

9:36 am - 10:43 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

14h 07m1 stop Philadelphia

7:15 am - 9:51 amORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

25h 36m2 stops Atlanta Hartsfield-Jackson Philadelphia

$250Frontier

Thu, Oct 29 - Fri, Oct 30

9:36 am - 10:43 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

14h 07m1 stop Philadelphia

8:00 am - 9:13 amORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

24h 13m1 stop Fort Lauderdale

$258Multiple Airlines

Thu, Dec 10 - Sun, Dec 13

9:39 pm - 7:02 pmCLT Charlotte Douglas-MDW Chicago Midway

22h 23m1 stop Orlando

8:07 pm - 8:44 pmMDW Chicago Midway-CLT Charlotte Douglas

23h 37m1 stop Orlando

$259Frontier

Thu, Oct 8 - Thu, Oct 15

9:43 am - 11:05 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 22mnonstop

6:29 am - 9:39 amORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 10mnonstop

$266American Airlines

Wed, Sep 30 - Thu, Oct 8

4:18 pm - 5:38 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 20mnonstop

7:55 am - 1:32 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

4h 37m1 stop Washington, D.C. Reagan-National

$267American Airlines

Mon, Oct 5 - Tue, Oct 6

9:00 pm - 11:55 pmCLT Charlotte Douglas-MDW Chicago Midway

3h 55m1 stop Nashville Intl

6:15 pm - 9:10 pmMDW Chicago Midway-CLT Charlotte Douglas

1h 55mnonstop

$267Southwest

Thu, Oct 1 - Mon, Oct 5

9:00 pm - 11:55 pmCLT Charlotte Douglas-MDW Chicago Midway

3h 55m1 stop Nashville Intl

6:55 pm - 9:50 pmMDW Chicago Midway-CLT Charlotte Douglas

1h 55mnonstop

$267Southwest

Thu, Oct 15 - Sat, Oct 17

6:45 am - 8:00 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 15mnonstop

10:54 am - 7:00 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

7h 06m1 stop Washington, D.C. Dulles Intl

$267United Airlines

Thu, Oct 15 - Sat, Oct 17

10:25 am - 2:26 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

5h 01m1 stop Washington, D.C. Dulles Intl

6:03 pm - 9:15 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 12mnonstop

$267United Airlines

Recent last minute flight deals from South Carolina to Chicago

Mon, Sep 14 - Fri, Sep 18

5:38 pm - 3:20 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

22h 42m1 stop Fort Lauderdale

6:00 am - 8:10 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

13h 10m1 stop Dallas/Fort Worth

$280Frontier

Mon, Sep 14 - Mon, Sep 21

9:32 am - 10:59 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

14h 27m1 stop Orlando

6:20 am - 2:28 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

7h 08m1 stop Baltimore/Washington

$280Frontier

Tue, Sep 15 - Thu, Sep 17

12:05 pm - 8:29 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

9h 24m1 stop Dallas/Fort Worth

11:30 am - 5:00 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

4h 30m1 stop Owensboro Daviess County

$285Multiple Airlines

Mon, Sep 14 - Thu, Sep 17

12:09 pm - 9:39 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

10h 30m1 stop Houston George Bush Intcntl

11:30 am - 5:00 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

4h 30m1 stop Owensboro Daviess County

$290Multiple Airlines

Thu, Sep 10 - Wed, Oct 14

6:00 am - 7:28 amCAE Columbia Metropolitan-ORD Chicago O'Hare Intl

2h 28mnonstop

1:10 pm - 4:20 pmORD Chicago O'Hare Intl-CAE Columbia Metropolitan

2h 10mnonstop

$414American Airlines

Thu, Sep 10 - Wed, Oct 14

10:49 am - 5:28 pmCAE Columbia Metropolitan-ORD Chicago O'Hare Intl

7h 39m1 stop Washington, D.C. Reagan-National

1:10 pm - 4:20 pmORD Chicago O'Hare Intl-CAE Columbia Metropolitan

2h 10mnonstop

$424American Airlines

Thu, Sep 10 - Wed, Sep 23

10:29 am - 11:59 amCAE Columbia Metropolitan-ORD Chicago O'Hare Intl

2h 30mnonstop

6:40 am - 9:54 amORD Chicago O'Hare Intl-CAE Columbia Metropolitan

2h 14mnonstop

$434United Airlines

Thu, Sep 10 - Thu, Sep 24

10:29 am - 11:59 amCAE Columbia Metropolitan-ORD Chicago O'Hare Intl

2h 30mnonstop

6:29 am - 9:46 amORD Chicago O'Hare Intl-CAE Columbia Metropolitan

2h 17mnonstop

$434United Airlines

Sat, Sep 12 - Tue, Sep 15

3:25 pm - 4:25 pmCLT Charlotte Douglas-MDW Chicago Midway

2h 00mnonstop

8:45 am - 11:55 amMDW Chicago Midway-CLT Charlotte Douglas

2h 10mnonstop

$449Southwest

Tue, Sep 15 - Tue, Sep 15

6:50 am - 10:50 amCLT Charlotte Douglas-MDW Chicago Midway

5h 00m1 stop Nashville Intl

6:10 pm - 9:15 pmMDW Chicago Midway-CLT Charlotte Douglas

2h 05mnonstop

$459Southwest

Recent direct flight deals from South Carolina to Chicago

Thu, Oct 8 - Thu, Oct 15

9:43 am - 11:05 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 22mnonstop

6:29 am - 9:39 amORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 10mnonstop

$266American Airlines

Tue, Oct 13 - Fri, Oct 16

7:25 am - 8:25 amCLT Charlotte Douglas-MDW Chicago Midway

2h 00mnonstop

6:55 pm - 9:50 pmMDW Chicago Midway-CLT Charlotte Douglas

1h 55mnonstop

$269Southwest

Mon, Oct 12 - Fri, Oct 16

10:50 pm - 12:08 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 18mnonstop

6:40 pm - 9:55 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 15mnonstop

$269American Airlines

Fri, Nov 13 - Mon, Nov 16

7:00 pm - 8:05 pmCLT Charlotte Douglas-MDW Chicago Midway

2h 05mnonstop

6:25 pm - 9:20 pmMDW Chicago Midway-CLT Charlotte Douglas

1h 55mnonstop

$269Southwest

Thu, Oct 15 - Fri, Oct 16

10:50 pm - 12:08 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 18mnonstop

6:40 pm - 9:55 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 15mnonstop

$269American Airlines

Sat, Oct 10 - Tue, Oct 13

4:10 pm - 5:05 pmCLT Charlotte Douglas-MDW Chicago Midway

1h 55mnonstop

6:15 pm - 9:10 pmMDW Chicago Midway-CLT Charlotte Douglas

1h 55mnonstop

$269Southwest

Sat, Dec 19 - Mon, Dec 21

5:34 pm - 7:00 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 26mnonstop

5:45 pm - 8:51 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 06mnonstop

$293United Airlines

Sat, Dec 26 - Thu, Dec 31

8:07 am - 9:30 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 23mnonstop

5:45 pm - 8:51 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 06mnonstop

$293United Airlines

Sat, Oct 10 - Mon, Oct 12

11:00 am - 12:22 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 22mnonstop

8:55 pm - 11:59 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 04mnonstop

$332Alaska Airlines

Sat, Oct 10 - Mon, Oct 12

4:30 pm - 5:51 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 21mnonstop

8:55 pm - 11:59 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 04mnonstop

$332Alaska Airlines

Useful Info

Low season	February
High season	July
Cheapest flight	$120

Best time to beat the crowds with an average 9% drop in price.

Most popular time to fly with an average 17% increase in price.

Flight from Greenville to Chicago O'Hare Airport

Verified travelerFlew with American Airlines-Apr 2026

Chicago has a enormous airport so be ready to walk and transfer to international flights by train via terminal

YesicaFlew with United Airlines-Feb 2026

Utilize the mobile app of your airline it will give you all the updates and information you need

EllenFlew with United Airlines-May 2024

Greenville airport is small, getting through security won't take too long (particularly if you have Precheck). Be prepared to walk for 10-15 minutes from your arrival gate in O'Hare to your next departure gate, if you have one. Sometimes those gates are really close together, but my experience is that they are typically farther apart and require a solid walk.

How does KAYAK find such low prices on flights from South Carolina to Chicago?
KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.
How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?
KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.
What is the Hacker Fare option on flights from South Carolina to Chicago?
Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.
What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?
Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Merrillville

Hammond

Saint Joseph

Portage

Lansing

Valparaiso

Munster

Schererville

Chesterton

Porter

Monticello

Saint John

Griffith

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$120 Find Cheap Flights from South Carolina to Chicago - Compare and Save

Cheap Flights from South Carolina to Chicago

Recent round-trip flight deals from South Carolina to Chicago

Recent one-way flight deals from South Carolina to Chicago

Recent last minute flight deals from South Carolina to Chicago

Recent direct flight deals from South Carolina to Chicago

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Flights from South Carolina to Chicago: the best tips from KAYAK users

FAQs for booking flights from South Carolina to Chicago

Traveling to a place near Chicago?

More options for your flight to Chicago

Complete your trip to Chicago with a hotel stay or car rental

Cabin class types available on flights to South Carolina

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Flights from domestic origins to Chicago

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