How does KAYAK find such low prices on flights from South Carolina to Chicago?

KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.

How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?

KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

What is the Hacker Fare option on flights from South Carolina to Chicago?

Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.

What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?

Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

$110 CHEAP FLIGHTS from South Carolina to Chicago

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Cheap Flights from South Carolina to Chicago

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Direct

Recent round-trip flight deals from South Carolina to Chicago

Tue, Oct 13 - Tue, Oct 20

3:00 pm - 7:51 amCHS Charleston-ORD Chicago O'Hare Intl

17h 51m1 stop Orlando

8:04 am - 1:24 pmORD Chicago O'Hare Intl-CHS Charleston

28h 20m2 stops Fort Lauderdale Tampa

$242Multiple Airlines

Tue, Oct 13 - Tue, Oct 20

8:10 am - 2:20 pmCHS Charleston-ORD Chicago O'Hare Intl

7h 10m1 stop Charlotte Douglas

8:40 pm - 11:59 pmORD Chicago O'Hare Intl-CHS Charleston

2h 19mnonstop

$243American Airlines

Wed, Oct 14 - Sat, Oct 17

6:50 pm - 8:29 pmCHS Charleston-ORD Chicago O'Hare Intl

2h 39mnonstop

7:00 am - 3:10 pmORD Chicago O'Hare Intl-CHS Charleston

7h 10m1 stop Washington, D.C. Reagan-National

$243United Airlines

Wed, Oct 14 - Sat, Oct 17

11:27 am - 1:00 pmCHS Charleston-ORD Chicago O'Hare Intl

2h 33mnonstop

6:06 pm - 12:15 amORD Chicago O'Hare Intl-CHS Charleston

5h 09m1 stop Washington, D.C. Dulles Intl

$243United Airlines

Wed, Oct 14 - Sat, Oct 17

7:15 am - 8:25 amCHS Charleston-MDW Chicago Midway

2h 10mnonstop

6:55 am - 1:25 pmMDW Chicago Midway-CHS Charleston

5h 30m1 stop Baltimore/Washington

$243Southwest

Wed, Oct 7 - Wed, Oct 7

5:02 am - 11:05 amCHS Charleston-ORD Chicago O'Hare Intl

7h 03m1 stop Charlotte Douglas

8:40 pm - 11:59 pmORD Chicago O'Hare Intl-CHS Charleston

2h 19mnonstop

$243American Airlines

Thu, Oct 15 - Mon, Oct 19

2:13 pm - 7:31 amCHS Charleston-ORD Chicago O'Hare Intl

18h 18m1 stop Orlando

8:11 pm - 2:38 pmORD Chicago O'Hare Intl-CHS Charleston

17h 27m1 stop Orlando

$250Multiple Airlines

Wed, Oct 14 - Sat, Oct 17

6:40 am - 10:55 amCHS Charleston-MDW Chicago Midway

5h 15m1 stop Nashville Intl

6:55 am - 1:25 pmMDW Chicago Midway-CHS Charleston

5h 30m1 stop Baltimore/Washington

$253Southwest

Wed, Dec 9 - Sat, Jan 9

6:19 am - 12:20 pmCHS Charleston-ORD Chicago O'Hare Intl

7h 01m1 stop Atlanta Hartsfield-Jackson

5:30 am - 1:47 pmORD Chicago O'Hare Intl-CHS Charleston

7h 17m1 stop Atlanta Hartsfield-Jackson

$253Delta

Wed, Dec 9 - Sat, Jan 9

11:24 am - 4:17 pmCHS Charleston-MDW Chicago Midway

5h 53m1 stop Atlanta Hartsfield-Jackson

10:35 am - 3:39 pmMDW Chicago Midway-CHS Charleston

4h 04m1 stop Atlanta Hartsfield-Jackson

$253Delta

Recent last minute flight deals from South Carolina to Chicago

Sun, Sep 20 - Fri, Sep 25

6:25 pm - 10:50 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

17h 25m1 stop Owensboro Daviess County

11:30 am - 5:00 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

4h 30m1 stop Owensboro Daviess County

$263Contour

Mon, Sep 21 - Wed, Sep 23

6:25 pm - 10:50 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

17h 25m1 stop Owensboro Daviess County

11:30 am - 5:00 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

4h 30m1 stop Owensboro Daviess County

$274Contour

Thu, Sep 17 - Fri, Oct 16

2:53 pm - 12:45 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

10h 52m1 stop Dallas/Fort Worth

6:00 am - 1:28 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

6h 28m1 stop Baltimore/Washington

$279Frontier

Fri, Sep 18 - Sun, Oct 18

7:16 pm - 10:59 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

28h 43m1 stop Orlando

6:00 am - 1:28 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

6h 28m1 stop Baltimore/Washington

$288Frontier

Fri, Sep 18 - Fri, Sep 25

6:12 am - 12:50 pmGSP Greenville-ORD Chicago O'Hare Intl

7h 38m1 stop Washington, D.C. Reagan-National

6:49 pm - 9:54 pmORD Chicago O'Hare Intl-GSP Greenville

2h 05mnonstop

$384American Airlines

Fri, Sep 18 - Fri, Sep 25

6:10 pm - 7:32 pmGSP Greenville-ORD Chicago O'Hare Intl

2h 22mnonstop

6:17 pm - 9:17 pmORD Chicago O'Hare Intl-GSP Greenville

2h 00mnonstop

$389United Airlines

Fri, Sep 18 - Fri, Sep 25

4:49 pm - 10:00 pmGSP Greenville-ORD Chicago O'Hare Intl

6h 11m1 stop Washington, D.C. Reagan-National

5:20 am - 1:10 pmORD Chicago O'Hare Intl-GSP Greenville

6h 50m1 stop Charlotte Douglas

$394American Airlines

Thu, Sep 17 - Fri, Oct 16

7:00 am - 12:08 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

6h 08m1 stop Newark

6:03 pm - 9:15 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 12mnonstop

$404United Airlines

Tue, Sep 15 - Wed, Sep 23

7:15 am - 12:39 pmGSP Greenville-MDW Chicago Midway

6h 24m1 stop Detroit Metropolitan Wayne County

6:05 am - 11:08 amMDW Chicago Midway-GSP Greenville

4h 03m1 stop Atlanta Hartsfield-Jackson

$423Delta

Wed, Sep 16 - Tue, Sep 22

7:15 am - 12:39 pmGSP Greenville-MDW Chicago Midway

6h 24m1 stop Detroit Metropolitan Wayne County

5:11 pm - 10:55 pmMDW Chicago Midway-GSP Greenville

4h 44m1 stop Atlanta Hartsfield-Jackson

$423Delta

Recent direct flight deals from South Carolina to Chicago

Thu, Oct 29 - Sat, Oct 31

7:17 am - 9:00 amCHS Charleston-ORD Chicago O'Hare Intl

2h 43mnonstop

8:40 pm - 11:59 pmORD Chicago O'Hare Intl-CHS Charleston

2h 19mnonstop

$252American Airlines

Tue, Dec 22 - Thu, Dec 24

6:21 am - 8:00 amCHS Charleston-ORD Chicago O'Hare Intl

2h 39mnonstop

2:43 pm - 6:03 pmORD Chicago O'Hare Intl-CHS Charleston

2h 20mnonstop

$252American Airlines

Sat, Oct 10 - Mon, Oct 12

7:16 am - 8:59 amCHS Charleston-ORD Chicago O'Hare Intl

2h 43mnonstop

8:40 pm - 11:59 pmORD Chicago O'Hare Intl-CHS Charleston

2h 19mnonstop

$252American Airlines

Wed, Oct 14 - Sat, Oct 17

7:15 am - 8:25 amCHS Charleston-MDW Chicago Midway

2h 10mnonstop

8:15 am - 11:20 amMDW Chicago Midway-CHS Charleston

2h 05mnonstop

$255Southwest

Fri, Oct 16 - Tue, Oct 20

6:45 am - 8:00 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 15mnonstop

6:03 pm - 9:15 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 12mnonstop

$267United Airlines

Wed, Feb 24 - Fri, Feb 26

1:05 pm - 2:29 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 24mnonstop

1:55 pm - 4:57 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 02mnonstop

$267United Airlines

Fri, Dec 25 - Tue, Dec 29

3:32 pm - 5:00 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 28mnonstop

5:45 pm - 8:51 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 06mnonstop

$267United Airlines

Sat, Nov 7 - Fri, Nov 13

7:55 am - 8:55 amCLT Charlotte Douglas-MDW Chicago Midway

2h 00mnonstop

6:40 pm - 9:40 pmMDW Chicago Midway-CLT Charlotte Douglas

2h 00mnonstop

$268Southwest

Fri, Oct 16 - Sat, Oct 24

7:25 pm - 8:20 pmCLT Charlotte Douglas-MDW Chicago Midway

1h 55mnonstop

8:05 am - 10:55 amMDW Chicago Midway-CLT Charlotte Douglas

1h 50mnonstop

$268Southwest

Thu, Dec 31 - Mon, Jan 4

6:43 pm - 8:29 pmCHS Charleston-ORD Chicago O'Hare Intl

2h 46mnonstop

12:00 pm - 3:20 pmORD Chicago O'Hare Intl-CHS Charleston

2h 20mnonstop

$269American Airlines

Useful Info

Low season	February
High season	July
Cheapest flight	$110

Best time to beat the crowds with an average 9% drop in price.

Most popular time to fly with an average 17% increase in price.

Flight from Charlotte to Chicago O'Hare Airport

Verified travelerFlew with American Airlines-Apr 2026

Chicago has a enormous airport so be ready to walk and transfer to international flights by train via terminal

YesicaFlew with United Airlines-Feb 2026

Utilize the mobile app of your airline it will give you all the updates and information you need

EllenFlew with United Airlines-May 2024

Greenville airport is small, getting through security won't take too long (particularly if you have Precheck). Be prepared to walk for 10-15 minutes from your arrival gate in O'Hare to your next departure gate, if you have one. Sometimes those gates are really close together, but my experience is that they are typically farther apart and require a solid walk.

How does KAYAK find such low prices on flights from South Carolina to Chicago?
KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.
How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?
KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.
What is the Hacker Fare option on flights from South Carolina to Chicago?
Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.
What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?
Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Merrillville

Hammond

Saint Joseph

Portage

Lansing

Valparaiso

Munster

Schererville

Chesterton

Porter

Monticello

Saint John

Griffith

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$110 Find Cheap Flights from South Carolina to Chicago - Compare and Save

Cheap Flights from South Carolina to Chicago

Recent round-trip flight deals from South Carolina to Chicago

Recent one-way flight deals from South Carolina to Chicago

Recent last minute flight deals from South Carolina to Chicago

Recent direct flight deals from South Carolina to Chicago

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Flights from South Carolina to Chicago: the best tips from KAYAK users

FAQs for booking flights from South Carolina to Chicago

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More options for your flight to Chicago

Complete your trip to Chicago with a hotel stay or car rental

Cabin class types available on flights to South Carolina

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