How does KAYAK find such low prices on flights from South Carolina to Chicago?

KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.

How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?

KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

What is the Hacker Fare option on flights from South Carolina to Chicago?

Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.

What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?

Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

$71 CHEAP FLIGHTS from South Carolina to Chicago

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Cheap Flights from South Carolina to Chicago

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Direct

Recent round-trip flight deals from South Carolina to Chicago

Wed, Sep 9 - Wed, Sep 16

12:23 pm - 2:45 pmSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

27h 22m1 stop Fort Lauderdale

7:11 am - 4:15 pmORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

8h 04m1 stop Fort Lauderdale

$160Multiple Airlines

Wed, Sep 9 - Sat, Sep 12

12:23 pm - 2:45 pmSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

27h 22m1 stop Fort Lauderdale

7:11 am - 4:15 pmORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

8h 04m1 stop Fort Lauderdale

$165Multiple Airlines

Sat, Sep 5 - Sun, Sep 6

3:24 pm - 5:00 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 36mnonstop

11:27 am - 2:53 pmORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 26mnonstop

$197United Airlines

Sat, Sep 5 - Sun, Sep 6

5:00 pm - 6:38 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 38mnonstop

8:15 am - 11:34 amORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 19mnonstop

$197American Airlines

Wed, Sep 16 - Sat, Sep 19

11:34 am - 4:13 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

5h 39m1 stop Detroit Metropolitan Wayne County

3:40 pm - 9:41 pmORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

5h 01m1 stop Atlanta Hartsfield-Jackson

$217Delta

Wed, Sep 30 - Sat, Oct 3

5:00 pm - 6:36 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 36mnonstop

11:55 am - 3:16 pmORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 21mnonstop

$219United Airlines

Sat, Sep 5 - Mon, Sep 7

5:00 pm - 6:38 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 38mnonstop

8:15 am - 11:34 amORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 19mnonstop

$226American Airlines

Sat, Sep 12 - Mon, Sep 14

3:25 pm - 4:25 pmCLT Charlotte Douglas-MDW Chicago Midway

2h 00mnonstop

8:00 am - 11:10 amMDW Chicago Midway-CLT Charlotte Douglas

2h 10mnonstop

$251Southwest

Sat, Sep 5 - Wed, Sep 9

5:15 pm - 8:35 pmCLT Charlotte Douglas-MDW Chicago Midway

4h 20m1 stop Baltimore/Washington

10:10 am - 7:05 pmMDW Chicago Midway-CLT Charlotte Douglas

7h 55m2 stops Lambert-St Louis Baltimore/Washington

$251Southwest

Sat, Sep 5 - Sun, Sep 6

6:41 pm - 10:36 pmCHS Charleston-MDW Chicago Midway

4h 55m1 stop Atlanta Hartsfield-Jackson

6:05 am - 1:52 pmMDW Chicago Midway-CHS Charleston

6h 47m1 stop Atlanta Hartsfield-Jackson

$257Delta

Recent last minute flight deals from South Carolina to Chicago

Wed, Aug 19 - Mon, Aug 24

6:25 pm - 10:50 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

17h 25m1 stop Owensboro Daviess County

11:30 am - 5:00 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

4h 30m1 stop Owensboro Daviess County

$258Contour

Wed, Aug 19 - Sun, Aug 23

6:25 pm - 10:50 amCLT Charlotte Douglas-ORD Chicago O'Hare Intl

17h 25m1 stop Owensboro Daviess County

11:30 am - 5:00 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

4h 30m1 stop Owensboro Daviess County

$258Contour

Tue, Aug 18 - Tue, Aug 25

10:47 am - 8:15 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

10h 28m1 stop Dallas/Fort Worth

5:59 pm - 8:01 amORD Chicago O'Hare Intl-CLT Charlotte Douglas

13h 02m1 stop Orlando

$265Frontier

Tue, Aug 18 - Wed, Aug 26

10:47 am - 8:15 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

10h 28m1 stop Dallas/Fort Worth

5:59 pm - 8:01 amORD Chicago O'Hare Intl-CLT Charlotte Douglas

13h 02m1 stop Orlando

$265Frontier

Tue, Aug 18 - Tue, Sep 1

10:59 am - 12:15 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

2h 16mnonstop

1:15 pm - 4:24 pmORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 09mnonstop

$307American Airlines

Tue, Aug 18 - Tue, Sep 1

9:23 am - 12:54 pmCLT Charlotte Douglas-ORD Chicago O'Hare Intl

4h 31m1 stop Washington, D.C. Reagan-National

6:49 am - 9:55 amORD Chicago O'Hare Intl-CLT Charlotte Douglas

2h 06mnonstop

$317American Airlines

Tue, Aug 18 - Tue, Aug 25

5:43 pm - 7:03 pmGSP Greenville-ORD Chicago O'Hare Intl

2h 20mnonstop

1:55 pm - 5:02 pmORD Chicago O'Hare Intl-GSP Greenville

2h 07mnonstop

$341United Airlines

Sun, Aug 16 - Sun, Aug 23

6:30 am - 7:47 amGSP Greenville-ORD Chicago O'Hare Intl

2h 17mnonstop

5:59 pm - 9:07 pmORD Chicago O'Hare Intl-GSP Greenville

2h 08mnonstop

$354United Airlines

Sat, Aug 15 - Wed, Aug 19

12:39 pm - 6:33 pmGSP Greenville-MDW Chicago Midway

6h 54m1 stop Detroit Metropolitan Wayne County

6:05 am - 11:07 amMDW Chicago Midway-GSP Greenville

4h 02m1 stop Atlanta Hartsfield-Jackson

$383Delta

Sat, Aug 15 - Wed, Aug 19

12:39 pm - 6:33 pmGSP Greenville-MDW Chicago Midway

6h 54m1 stop Detroit Metropolitan Wayne County

5:10 pm - 10:59 pmMDW Chicago Midway-GSP Greenville

4h 49m1 stop Atlanta Hartsfield-Jackson

$383Delta

Recent direct flight deals from South Carolina to Chicago

Sat, Sep 5 - Sun, Sep 6

3:24 pm - 5:00 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 36mnonstop

11:27 am - 2:53 pmORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 26mnonstop

$197United Airlines

Sat, Sep 5 - Sun, Sep 6

5:00 pm - 6:38 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 38mnonstop

8:15 am - 11:34 amORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 19mnonstop

$197American Airlines

Wed, Sep 30 - Sat, Oct 3

5:00 pm - 6:36 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 36mnonstop

11:55 am - 3:16 pmORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 21mnonstop

$219United Airlines

Tue, Sep 29 - Sat, Oct 3

5:00 pm - 6:36 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 36mnonstop

11:55 am - 3:16 pmORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 21mnonstop

$219United Airlines

Sat, Sep 5 - Mon, Sep 7

5:00 pm - 6:38 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 38mnonstop

8:15 am - 11:34 amORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 19mnonstop

$226American Airlines

Thu, Sep 3 - Sun, Sep 6

6:21 pm - 7:56 pmMYR Myrtle Beach Intl-ORD Chicago O'Hare Intl

2h 35mnonstop

11:27 am - 2:53 pmORD Chicago O'Hare Intl-MYR Myrtle Beach Intl

2h 26mnonstop

$226United Airlines

Sat, Sep 5 - Sun, Sep 6

12:07 pm - 1:43 pmSAV Savannah/Hilton Head-ORD Chicago O'Hare Intl

2h 36mnonstop

8:00 am - 11:22 amORD Chicago O'Hare Intl-SAV Savannah/Hilton Head

2h 22mnonstop

$237American Airlines

Sat, Sep 12 - Mon, Sep 14

3:25 pm - 4:25 pmCLT Charlotte Douglas-MDW Chicago Midway

2h 00mnonstop

8:00 am - 11:10 amMDW Chicago Midway-CLT Charlotte Douglas

2h 10mnonstop

$251Southwest

Fri, Oct 23 - Mon, Oct 26

7:40 am - 8:40 amCLT Charlotte Douglas-MDW Chicago Midway

2h 00mnonstop

7:45 am - 10:35 amMDW Chicago Midway-CLT Charlotte Douglas

1h 50mnonstop

$253Southwest

Fri, Oct 2 - Mon, Oct 5

7:25 pm - 8:20 pmCLT Charlotte Douglas-MDW Chicago Midway

1h 55mnonstop

7:45 am - 10:35 amMDW Chicago Midway-CLT Charlotte Douglas

1h 50mnonstop

$253Southwest

Useful Info

Low season	February
High season	October
Cheapest flight	$71

Best time to beat the crowds with an average 8% drop in price.

Most popular time to fly and prices are also 5% lower on average.

Flight from Myrtle Beach to Chicago O'Hare Airport

Verified travelerFlew with American Airlines-Apr 2026

Chicago has a enormous airport so be ready to walk and transfer to international flights by train via terminal

YesicaFlew with United Airlines-Feb 2026

Utilize the mobile app of your airline it will give you all the updates and information you need

EllenFlew with United Airlines-May 2024

Greenville airport is small, getting through security won't take too long (particularly if you have Precheck). Be prepared to walk for 10-15 minutes from your arrival gate in O'Hare to your next departure gate, if you have one. Sometimes those gates are really close together, but my experience is that they are typically farther apart and require a solid walk.

How does KAYAK find such low prices on flights from South Carolina to Chicago?
KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.
How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?
KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.
What is the Hacker Fare option on flights from South Carolina to Chicago?
Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.
What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?
Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Merrillville

Saint Joseph

Hammond

Portage

Lansing

Valparaiso

Munster

Chesterton

Schererville

Porter

Monticello

Saint John

Griffith

Everything you need to know for your flight to Chicago

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Return flight deals

Cabin class types available on flights to South Carolina

First Class flights to Chicagofrom $497

Business Class flights to Chicagofrom $569

Premium Economy Class flights to Chicagofrom $643

Economy Class flights to Chicagofrom $237

$71 Find Cheap Flights from South Carolina to Chicago - Compare and Save

Cheap Flights from South Carolina to Chicago

Recent round-trip flight deals from South Carolina to Chicago

Recent one-way flight deals from South Carolina to Chicago

Recent last minute flight deals from South Carolina to Chicago

Recent direct flight deals from South Carolina to Chicago

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High season

Cheapest flight

Flights from South Carolina to Chicago: the best tips from KAYAK users

FAQs for booking flights from South Carolina to Chicago

Traveling to a place near Chicago?

Everything you need to know for your flight to Chicago

Cabin class types available on flights to South Carolina

Complete your trip to Chicago with a hotel stay or car rental

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Choose which airport to fly into in Chicago

Find deals for your return flight