How does KAYAK find such low prices on flights from South Carolina to Chicago?

KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago. Visit our flight page for the latest deals!>/a>

How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?

KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now. Visit our flight page for the latest deals!>/a>

What is the Hacker Fare option on flights from South Carolina to Chicago?

Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline. Visit our flight page for the latest deals!>/a>

What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?

Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best. Visit our flight page for the latest deals!>/a>

$92 CHEAP FLIGHTS from South Carolina to Chicago

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Cheap Flights from South Carolina to Chicago

Discover the best prices for you by selecting your travel dates on KAYAK.

Round-trip

One-way

Last minute

Direct

Recent round-trip flight deals from South Carolina to Chicago

Wed, Jul 15 - Wed, Jul 22

3:15 pm - 4:49 pm

MYR

ORD

2h 34mnonstop

11:00 am - 2:19 pm

ORD

MYR

2h 19mnonstop

$197United Airlines

Tue, Jul 14 - Tue, Jul 21

11:34 am - 4:23 pm

MYR

ORD

5h 49m

1 stop

5:30 am - 10:47 am

ORD

MYR

4h 17m

1 stop

$217Delta

Sat, Sep 19 - Sat, Sep 26

11:54 am - 3:35 pm

CAE

MDW

4h 41m

1 stop

6:05 am - 11:08 am

MDW

CAE

4h 03m

1 stop

$217Delta

Thu, Aug 20 - Sat, Aug 22

10:05 am - 12:25 pm

SAV

ORD

27h 20m

1 stop

7:55 am - 5:55 pm

ORD

SAV

9h 00m

1 stop

$223Multiple Airlines

Fri, Jul 17 - Wed, Jul 22

6:41 pm - 12:15 pm

CLT

ORD

18h 34m

1 stop

5:13 pm - 4:58 pm

ORD

CLT

22h 45m

1 stop

$247Frontier

Thu, Jul 16 - Tue, Jul 21

5:57 pm - 12:49 am

CLT

ORD

7h 52m

1 stop

8:05 am - 9:07 pm

ORD

CLT

12h 02m

1 stop

$249Frontier

Fri, Aug 14 - Wed, Aug 19

6:41 pm - 12:15 pm

CLT

ORD

18h 34m

1 stop

11:30 am - 5:00 pm

ORD

CLT

4h 30m

1 stop

$252Multiple Airlines

Thu, Aug 6 - Sun, Aug 9

6:25 pm - 10:50 am

CLT

ORD

17h 25m

1 stop

11:30 am - 5:00 pm

ORD

CLT

4h 30m

1 stop

$253Contour

Tue, Sep 15 - Mon, Sep 21

11:56 am - 1:33 pm

SAV

ORD

2h 37mnonstop

8:00 am - 11:26 am

ORD

SAV

2h 26mnonstop

$258American Airlines

Tue, Jun 30 - Tue, Jul 7

12:23 pm - 2:03 pm

MYR

ORD

2h 40mnonstop

9:00 am - 12:26 pm

ORD

MYR

2h 26mnonstop

$266American Airlines

Useful Info

Low season	January
High season	July
Cheapest flight	$92

Best time to beat the crowds with an average 15% drop in price.

Most popular time to fly and prices are also 8% lower on average.

Flight from Greenville to Chicago O'Hare Airport

Verified travelerFlew with American Airlines

GSP

ORD

Apr 2026

Chicago has a enormous airport so be ready to walk and transfer to international flights by train via terminal

YesicaFlew with United Airlines

CHS

ORD

Feb 2026

Utilize the mobile app of your airline it will give you all the updates and information you need

EllenFlew with United Airlines

GSP

ORD

May 2024

Greenville airport is small, getting through security won't take too long (particularly if you have Precheck). Be prepared to walk for 10-15 minutes from your arrival gate in O'Hare to your next departure gate, if you have one. Sometimes those gates are really close together, but my experience is that they are typically farther apart and require a solid walk.

How does KAYAK find such low prices on flights from South Carolina to Chicago?
KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Chicago.
How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Chicago?
KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Chicago from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.
What is the Hacker Fare option on flights from South Carolina to Chicago?
Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Chicago with an airline and back to South Carolina with another airline.
What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Chicago?
Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Chicago from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Merrillville

Saint Joseph

Hammond

Portage

Lansing

Valparaiso

Schererville

Munster

Chesterton

Porter

Monticello

Saint John

Griffith

Everything you need to know for your flight to Chicago

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Complete your trip

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Return flight deals

Cabin class types available on flights to South Carolina

First Class flights to Chicagofrom $554

Business Class flights to Chicagofrom $554

Premium Economy Class flights to Chicagofrom $519

Economy Class flights to Chicagofrom $227

$92 Find Cheap Flights from South Carolina to Chicago

KAYAK searches hundreds of travel sites at once for deals on flights to Chicago

Cheap Flights from South Carolina to Chicago

Recent round-trip flight deals from South Carolina to Chicago

Recent one-way flight deals from South Carolina to Chicago

Recent last minute flight deals from South Carolina to Chicago

Recent direct flight deals from South Carolina to Chicago

Good to know

Flights from South Carolina to Chicago: the best tips from KAYAK users

FAQs for booking flights from South Carolina to Chicago

Traveling to a place near Chicago?

Everything you need to know for your flight to Chicago

Cabin class types available on flights to South Carolina

Complete your trip to Chicago with a hotel stay or car rental

Find direct flights for Chicago

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Flights from domestic origins to Chicago

Choose which airport to fly into in Chicago

Find deals for your return flight