MDE - GRU

$282 Find Cheap Flights from Medellín to Sao Paulo

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to Sao Paulo departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Sao Paulo Guarulhos Intl Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Sao Paulo, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Sao Paulo, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 21% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$434
Typical prices: $381-$484
Copa Airlines
Sat 8/15Fri 8/21
MDE - GRU • 1 stop
Cheapest one-way
$282
Typical prices: $254-$376
LATAM Airlines
Sat 8/22
MDE - GRU • 2 stops
Top airlines
Cheapest • from $434 (round-trip)
Best reviews • 7.6 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Medellín and Sao Paulo. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $477 (round-trip)
Shortest trip • 9h 02m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 5 weeks in advance save around 30% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 16% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Sao Paulo!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Medellín to Sao Paulo (MDE-GRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to Sao Paulo that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to Sao Paulo

Sat, Aug 15 - Fri, Aug 21
Copa Airlines Logo
8:35 am - 12:10 am
MDE
-
GRU
13h 35m
1 stop
Copa Airlines Logo
5:00 am - 10:50 pm
GRU
-
MDE
19h 50m
1 stop
$434Copa Airlines
Tue, Jul 7 - Thu, Jul 30
Copa Airlines Logo
9:15 am - 12:30 am
MDE
-
GRU
13h 15m
1 stop
Copa Airlines Logo
5:00 am - 2:45 pm
GRU
-
MDE
11h 45m
1 stop
$435Copa Airlines
Wed, Jul 15 - Wed, Jul 22
LATAM Airlines Logo
6:55 am - 8:20 pm
MDE
-
GRU
11h 25m
1 stop
LATAM Airlines Logo
11:45 pm - 9:20 am
GRU
-
MDE
11h 35m
1 stop
$445LATAM Airlines
Tue, Jun 30 - Mon, Jul 6
Copa Airlines Logo
10:35 am - 12:30 am
MDE
-
GRU
11h 55m
1 stop
Copa Airlines Logo
2:00 am - 2:45 pm
GRU
-
MDE
14h 45m
1 stop
$475Copa Airlines
Tue, Jun 30 - Tue, Jul 7
Copa Airlines Logo
9:15 am - 8:50 pm
MDE
-
GRU
9h 35m
1 stop
Copa Airlines Logo
3:15 am - 10:55 am
GRU
-
MDE
9h 40m
1 stop
$476Copa Airlines
Wed, Aug 26 - Sun, Aug 30
LATAM Airlines Logo
8:50 am - 8:20 pm
MDE
-
GRU
9h 30m
1 stop
LATAM Airlines Logo
8:15 am - 3:55 pm
GRU
-
MDE
9h 40m
1 stop
$485LATAM Airlines
Wed, Aug 26 - Sun, Aug 30
LATAM Airlines Logo
8:50 am - 8:20 pm
MDE
-
GRU
9h 30m
1 stop
LATAM Airlines Logo
8:15 am - 3:55 pm
GRU
-
MDE
9h 40m
1 stop
$486LATAM Airlines
Wed, Jun 24 - Sun, Jun 28
Copa Airlines Logo
5:00 am - 8:50 pm
MDE
-
GRU
13h 50m
1 stop
Copa Airlines Logo
3:15 am - 10:55 am
GRU
-
MDE
9h 40m
1 stop
$489Copa Airlines
Sat, Aug 15 - Fri, Aug 21
LATAM Airlines Logo
6:35 pm - 5:30 am
MDE
-
GRU
8h 55m
1 stop
LATAM Airlines Logo
11:45 pm - 11:55 am
GRU
-
MDE
14h 10m
2 stops
$497LATAM Airlines
Sat, Jul 4 - Wed, Aug 26
LATAM Airlines Logo
6:15 pm - 6:10 am
MDE
-
GRU
9h 55m
1 stop
LATAM Airlines Logo
8:15 am - 3:55 pm
GRU
-
MDE
9h 40m
1 stop
$500LATAM Airlines
Booking Insights

KAYAK's insights & trends for Medellín to Sao Paulo flights

Get data-powered insights and trends into flights from Medellín to Sao Paulo to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Medellín Jose Maria Cordova Intl Airport to Sao Paulo Guarulhos Intl Airport?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Medellín Jose Maria Cordova Intl Airport to Sao Paulo Guarulhos Intl Airport departing in August.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Sao Paulo Guarulhos Intl Airport?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Sao Paulo Guarulhos Intl Airport, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to Sao Paulo Guarulhos Intl Airport is September, where tickets cost $382 (return) on average. On the other hand, the most expensive months are June and January, where the average cost of round-trip tickets is $546 and $510 respectively.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to Sao Paulo Guarulhos Intl Airport?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Sao Paulo Guarulhos Intl Airport, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to Sao Paulo Guarulhos Intl Airport, you should book around 5 weeks before departure, which saves you about 30% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 20 weeks before departure.

Good to know

Low seasonJanuary
Cheapest flight$282
Best time to beat the crowds but there is an average 11% increase in price.
Most popular time to fly and prices are also 13% lower on average.
Flight from Medellín to Sao Paulo

When to book flights from Medellín to Sao Paulo

Are your dates flexible? Find out the best times to travel from Medellín to Sao Paulo based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to Sao Paulo flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to Sao Paulo Guarulhos Intl Airport?

    In the last 5 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to Sao Paulo Guarulhos Intl Airport was $282 for a one-way ticket and $434 for a round-trip.

  • Do I need a passport to fly between Medellín and Sao Paulo?

    Yes

  • Which airports will I be using when flying from Medellín to Sao Paulo?

    Medellín and Sao Paulo are both served by 1 main airport. You will leave Medellín from Medellín Jose Maria Cordova Intl and will be arriving at Sao Paulo Guarulhos Intl.

  • Which aircraft models fly most regularly from Medellín to Sao Paulo?

    The Airbus A320neo is the aircraft model that flies most regularly on the Medellín to Sao Paulo flight route.

  • Which airline alliances offer flights from Medellín to Sao Paulo?

    Star Alliance is the only airline alliance operating flights between Medellín and Sao Paulo.

  • How does KAYAK find such low prices on flights from Medellín to Sao Paulo?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to Sao Paulo.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to Sao Paulo?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Sao Paulo from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to Sao Paulo?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Sao Paulo with an airline and back to Medellín with another airline. Booking your flights between Medellín and GRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to Sao Paulo?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Sao Paulo from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Medellín to Sao Paulo

 
See real verified KAYAK customer reviews for airlines flying from Medellín to Sao Paulo. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to Sao Paulo? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.6
Copa AirlinesOverall score based on 1567 reviews
7.8Boarding
8.1Crew
7.4Comfort
6.9Food
6.8Entertainment
Airline reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

6.0 GoodAnonymous, May 2026
SCL - PTY
Read more Copa Airlines reviews

They didn’t have any headphones for the entertainment screen and their USB port didn’t accommodate a USB-C for more modern phones. The food was just ok. The staff was friendly but the seats were very uncomfortable for a full flight.

Entire experience from check in to landing was amazing the flight crew was excellent and friendly. Seats were comfortable.

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Avoid at all costs. My wife had to stay back on a connecting flight as her parents flight was delayed. 10 days later on the way back they cancelled all our flights. We had to rebook all four of us on the next days flight.

Flight got delayed; had to go through security three times.

Copa staff at PTY and one particular crew member were unhelpful & rude.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Some of the Air hostesses are not that friendly. Need improvement

Everything you need to know for your flight from Medellín to Sao Paulo

Information on your arrival and departure airports