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Find Flight Deals from United States to Santiago

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights to Santiago

(Round-trip)
Depart: Tue Jan 13 2015 Return: Tue Jan 20 2015 Trip spans 8 days
Spirit Airlines
Spirit Airlines
FLL
6:40p
STI
8:37p
1h 57m
nonstop
STI
10:39p
FLL
1:00a
2h 21m
nonstop
Depart: Tue Jan 20 2015 Return: Tue Jan 27 2015 Trip spans 8 days
Spirit Airlines
Spirit Airlines
MCO
4:48p
STI
8:37p
3h 49m
1 stop
STI
10:39p
MCO
3:57a
5h 18m
1 stop
Depart: Thu Jan 1 2015 Return: Sun Jan 18 2015 Trip spans 18 days
American Airlines
American Airlines
TPA
2:35a
STI
9:41a
7h 06m
1 stop
STI
12:40p
TPA
6:50p
6h 10m
1 stop
Depart: Sun Jan 18 2015 Return: Sat Jan 24 2015 Trip spans 7 days
Delta
Delta
JAX
1:14a
STI
5:59p
16h 45m
1 stop
STI
3:55p
JAX
7:50a
15h 55m
1 stop
Depart: Tue Feb 17 2015 Return: Tue Mar 17 2015 Trip spans 28 days
Spirit Airlines
Spirit Airlines
HOU
9:00a
STI
7:36p
10h 36m
1 stop
STI
10:37p
HOU
8:33a
9h 56m
2 stops
Depart: Sat May 16 2015 Return: Sat May 23 2015 Trip spans 8 days
Delta
Delta
PBI
3:00p
STI
8:40a
17h 40m
2 stops
STI
2:50p
PBI
9:55a
19h 05m
2 stops
Depart: Mon Jan 19 2015 Return: Mon Jan 26 2015 Trip spans 8 days
American Airlines
American Airlines
MIA
7:35a
STI
9:37a
2h 02m
nonstop
STI
12:40p
MIA
2:59p
2h 19m
nonstop
Depart: Tue Feb 10 2015 Return: Tue Feb 24 2015 Trip spans 15 days
Spirit Airlines
Spirit Airlines
MSY
2:43p
STI
7:37p
4h 54m
1 stop
STI
10:37p
MSY
6:40a
8h 03m
1 stop
Depart: Tue Dec 30 2014 Return: Tue Jan 20 2015 Trip spans 22 days
American Airlines
American Airlines
EWR
12:59a
STI
9:41a
8h 42m
1 stop
STI
12:40p
EWR
7:55p
7h 15m
1 stop
Depart: Thu Feb 19 2015 Return: Mon Mar 2 2015 Trip spans 12 days
American Airlines
American Airlines
BOS
12:15a
STI
10:00a
9h 45m
1 stop
STI
12:40p
BOS
8:02p
7h 22m
1 stop
Depart: Tue Mar 24 2015 Return: Fri Mar 27 2015 Trip spans 4 days
Spirit Airlines
Spirit Airlines
LGA
3:45p
STI
9:50p
6h 05m
1 stop
STI
10:37p
LGA
6:00a
7h 23m
1 stop
Depart: Sun Feb 8 2015 Return: Wed Feb 18 2015 Trip spans 11 days
Delta
Delta
JFK
9:59a
STI
1:54p
3h 55m
nonstop
STI
2:45a
JFK
6:28a
3h 43m
nonstop
Depart: Wed Apr 15 2015 Return: Wed Apr 22 2015 Trip spans 8 days
United
United
PIT
3:30a
STI
9:45a
6h 15m
1 stop
STI
10:35a
PIT
6:38p
8h 03m
1 stop
Depart: Tue May 12 2015 Return: Sun May 17 2015 Trip spans 6 days
Spirit Airlines
Spirit Airlines
BWI
2:30p
STI
9:52p
7h 22m
1 stop
STI
10:47p
BWI
5:36a
6h 49m
1 stop
Depart: Sun May 24 2015 Return: Thu May 28 2015 Trip spans 5 days
Spirit Airlines
Spirit Airlines
DFW
1:00p
STI
8:52p
7h 52m
1 stop
STI
10:47p
DFW
6:41a
7h 54m
1 stop
Depart: Fri May 15 2015 Return: Sat May 23 2015 Trip spans 9 days
Delta
Delta
DEN
8:30p
STI
11:50a
15h 20m
1 stop
STI
2:50p
DEN
9:10a
18h 20m
1 stop
Depart: Wed Dec 24 2014 Return: Sat Dec 27 2014 Trip spans 4 days
American Airlines
American Airlines
ORD
3:10p
STI
8:41a
17h 31m
2 stops
STI
11:47a
ORD
8:24p
8h 37m
1 stop
Depart: Mon Jun 1 2015 Return: Tue Jun 30 2015 Trip spans 30 days
Copa Airlines
Copa Airlines
LAX
2:17a
STI
8:04a
29h 47m
1 stop
STI
11:54a
LAX
10:39p
10h 45m
1 stop
Depart: Sat Jun 6 2015 Return: Wed Jun 17 2015 Trip spans 12 days
Delta
Delta
CLT
2:15p
STI
6:46a
16h 31m
2 stops
STI
2:50p
CLT
8:32a
17h 42m
2 stops
Depart: Sat Jun 13 2015 Return: Sun Jun 28 2015 Trip spans 16 days
United
United
SEA
7:45a
STI
5:55a
22h 10m
2 stops
STI
9:50a
SEA
9:15a
23h 25m
2 stops
Change your search
Airports
Origin

Charlotte
$537
Seattle
$572
Chicago
$489
Fort Lauderdale
$244
Miami
$386
New York City
only $422
only $418
West Palm Beach
$379
Baltimore
$438
Orlando
$338
New Orleans
$398
Los Angeles
$496
Newark
$400
Denver
$476
Dallas
$438
Tampa
$360
Jacksonville
$374
Houston
$377
Boston
$400
Pittsburgh
$436
Destination

Santiago de los Caballeros
$244