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Find Flight Deals from United States to Santiago

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights to Santiago

(Round-trip)
Depart: Tue Jan 20 2015 Return: Tue Jan 27 2015 Trip spans 8 days
Spirit Airlines
Spirit Airlines
FLL
6:40p
STI
8:37p
1h 57m
nonstop
STI
10:39p
FLL
1:00a
2h 21m
nonstop
Depart: Tue Feb 3 2015 Return: Tue Feb 24 2015 Trip spans 22 days
Spirit Airlines
Spirit Airlines
MCO
4:48p
STI
8:37p
3h 49m
1 stop
STI
10:37p
MCO
3:59a
5h 22m
1 stop
Depart: Mon Jan 12 2015 Return: Mon Jan 19 2015 Trip spans 8 days
American Airlines
American Airlines
TPA
5:00a
STI
9:37a
4h 37m
1 stop
STI
12:40p
TPA
6:50p
6h 10m
1 stop
Depart: Wed Feb 11 2015 Return: Sun Feb 15 2015 Trip spans 5 days
Delta
Delta
JAX
1:14a
STI
5:59p
16h 45m
1 stop
STI
2:50p
JAX
7:05a
16h 15m
1 stop
Depart: Fri Mar 6 2015 Return: Sun Mar 8 2015 Trip spans 2 days
Delta
Delta
PBI
7:10a
STI
6:17p
11h 07m
1 stop
STI
2:50p
PBI
7:30a
16h 40m
1 stop
Depart: Sat Jan 17 2015 Return: Mon Jan 26 2015 Trip spans 10 days
American Airlines
American Airlines
MIA
7:35a
STI
9:37a
2h 02m
nonstop
STI
12:40p
MIA
2:59p
2h 19m
nonstop
Depart: Tue Mar 17 2015 Return: Thu Apr 16 2015 Trip spans 31 days
Spirit Airlines
Spirit Airlines
MSY
3:47p
STI
8:50p
5h 03m
1 stop
STI
10:47p
MSY
5:20a
6h 33m
1 stop
Depart: Tue Dec 30 2014 Return: Tue Jan 20 2015 Trip spans 22 days
American Airlines
American Airlines
EWR
12:59a
STI
9:41a
8h 42m
1 stop
STI
12:40p
EWR
7:55p
7h 15m
1 stop
Depart: Thu Jan 29 2015 Return: Mon Feb 2 2015 Trip spans 5 days
United
United
BOS
1:39a
STI
8:45a
7h 06m
1 stop
STI
10:40a
BOS
6:55p
8h 15m
1 stop
Depart: Thu Apr 16 2015 Return: Sun Apr 19 2015 Trip spans 4 days
Spirit Airlines
Spirit Airlines
LGA
6:50a
STI
9:52p
15h 02m
1 stop
STI
10:47p
LGA
6:00a
7h 13m
1 stop
Depart: Thu Feb 5 2015 Return: Sun Feb 8 2015 Trip spans 4 days
Delta
Delta
JFK
3:30a
STI
7:24a
3h 54m
nonstop
STI
9:24a
JFK
1:18p
3h 54m
nonstop
Depart: Thu Jun 4 2015 Return: Sun Jun 7 2015 Trip spans 4 days
Spirit Airlines
Spirit Airlines
ATL
3:50p
STI
9:52p
6h 02m
1 stop
STI
10:47p
ATL
1:48p
15h 01m
1 stop
Depart: Wed Dec 24 2014 Return: Sat Dec 27 2014 Trip spans 4 days
American Airlines
American Airlines
ORD
3:10p
STI
8:41a
17h 31m
2 stops
STI
11:47a
ORD
8:24p
8h 37m
1 stop
Depart: Tue Dec 23 2014 Return: Sat Dec 27 2014 Trip spans 5 days
United
United
RDU
11:32a
STI
10:44p
11h 12m
1 stop
STI
1:00a
RDU
9:07a
8h 07m
1 stop
Depart: Mon Jun 8 2015 Return: Mon Jun 29 2015 Trip spans 22 days
Delta
Delta
BDL
11:30a
STI
9:16a
21h 46m
2 stops
STI
2:50p
BDL
1:40p
22h 50m
2 stops
Depart: Sun Apr 19 2015 Return: Sat Apr 25 2015 Trip spans 7 days
United
United
SFO
5:30p
STI
6:45a
13h 15m
1 stop
STI
8:50p
SFO
12:07p
15h 17m
1 stop
Depart: Sun May 10 2015 Return: Sun May 24 2015 Trip spans 15 days
United
United
HOU
1:30p
STI
7:55a
18h 25m
2 stops
STI
9:50a
HOU
8:25p
10h 35m
1 stop
Change your search
Airports
Origin

Raleigh
$496
Chicago
$489
Fort Lauderdale
$224
Miami
$386
New York City
only $422
only $418
West Palm Beach
$374
San Francisco
$508
Atlanta
$438
Orlando
$338
New Orleans
$398
Hartford
$504
Newark
$400
Tampa
$360
Jacksonville
$374
Houston
$656
Boston
$400
Destination

Santiago de los Caballeros
$224