Find Flight Deals from United States to Santiago

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights to Santiago

(Round-trip)
Depart: Tue Feb 3 2015 Return: Tue Feb 17 2015 Trip spans 15 days
Spirit Airlines
Spirit Airlines
FLL
6:40p
STI
8:37p
1h 57m
nonstop
STI
10:37p
FLL
1:00a
2h 23m
nonstop
Depart: Tue Feb 24 2015 Return: Fri Feb 27 2015 Trip spans 4 days
Spirit Airlines
Spirit Airlines
MCO
4:44p
STI
8:36p
3h 52m
1 stop
STI
10:37p
MCO
3:55a
5h 18m
1 stop
Depart: Wed Feb 11 2015 Return: Fri Feb 13 2015 Trip spans 3 days
American Airlines
American Airlines
TPA
2:35a
STI
9:37a
7h 02m
1 stop
STI
12:40p
TPA
6:50p
6h 10m
1 stop
Depart: Fri Jan 30 2015 Return: Thu Feb 19 2015 Trip spans 21 days
American Airlines
American Airlines
MIA
7:35a
STI
9:37a
2h 02m
nonstop
STI
12:40p
MIA
2:59p
2h 19m
nonstop
Depart: Thu Jan 29 2015 Return: Sun Feb 1 2015 Trip spans 4 days
Delta
Delta
BOS
1:00a
STI
7:24a
6h 24m
1 stop
STI
2:05a
BOS
10:23a
8h 18m
1 stop
Depart: Sat Feb 21 2015 Return: Wed Feb 25 2015 Trip spans 5 days
American Airlines
American Airlines
EWR
12:50a
STI
10:27a
9h 37m
1 stop
STI
12:40p
EWR
7:55p
7h 15m
1 stop
Depart: Thu Jun 11 2015 Return: Tue Jun 16 2015 Trip spans 6 days
Spirit Airlines
Spirit Airlines
MSY
3:25p
STI
8:52p
5h 27m
1 stop
STI
10:47p
MSY
5:20a
6h 33m
1 stop
Depart: Tue Apr 7 2015 Return: Thu Apr 23 2015 Trip spans 17 days
Spirit Airlines
Spirit Airlines
LGA
6:50a
STI
9:50p
15h 00m
1 stop
STI
10:47p
LGA
6:00a
7h 13m
1 stop
Depart: Thu Jul 9 2015 Return: Tue Jul 21 2015 Trip spans 13 days
Spirit Airlines
Spirit Airlines
HOU
10:00a
STI
8:51p
10h 51m
1 stop
STI
10:47p
HOU
7:12a
8h 25m
2 stops
Depart: Sat May 9 2015 Return: Sat May 16 2015 Trip spans 8 days
American Airlines
American Airlines
DCA
2:00a
STI
4:57p
14h 57m
1 stop
STI
5:00a
DCA
5:14p
12h 14m
1 stop
Depart: Wed Jul 8 2015 Return: Sun Jul 19 2015 Trip spans 12 days
Multiple Airlines
Multiple Airlines
PDX
1:45a
STI
5:55a
28h 10m
2 stops
STI
3:15a
PDX
10:57a
31h 42m
1 stop
Depart: Sat Apr 25 2015 Return: Sat May 2 2015 Trip spans 8 days
American Airlines
American Airlines
JFK
9:40a
STI
4:57p
7h 17m
1 stop
STI
5:00a
JFK
6:58p
13h 58m
1 stop
Change your search
Airports
Origin

New York
only $479
only $419
Portland
$462
Orlando
$339
Fort Lauderdale
$224
New Orleans
$414
Newark
$401
Tampa
$343
Washington
$435
Houston
$432
Boston
$401
Miami
$386
Destination

Santiago de los Caballeros
$224