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Find Flight Deals from United States to Santiago

Dates flexible? Here are the best fares found in the past 48 hours...

Book cheap flights to Santiago

(Round-trip)
Depart: Tue Jan 13 2015 Return: Fri Jan 16 2015 Trip spans 4 days
Spirit Airlines
Spirit Airlines
FLL
6:40p
STI
8:37p
1h 57m
nonstop
STI
10:39p
FLL
1:00a
2h 21m
nonstop
Depart: Tue Jan 20 2015 Return: Tue Mar 3 2015 Trip spans 43 days
Spirit Airlines
Spirit Airlines
MCO
4:48p
STI
8:37p
3h 49m
1 stop
STI
10:37p
MCO
3:59a
5h 22m
1 stop
Depart: Wed Jan 14 2015 Return: Mon Jan 19 2015 Trip spans 6 days
American Airlines
American Airlines
TPA
5:00a
STI
9:37a
4h 37m
1 stop
STI
12:40p
TPA
6:50p
6h 10m
1 stop
Depart: Fri Mar 6 2015 Return: Sun Mar 8 2015 Trip spans 2 days
Delta
Delta
PBI
7:10a
STI
6:17p
11h 07m
1 stop
STI
2:50p
PBI
7:30a
16h 40m
1 stop
Depart: Wed May 20 2015 Return: Sun May 24 2015 Trip spans 5 days
Delta
Delta
JAX
2:00a
STI
1:50p
11h 50m
1 stop
STI
3:15a
JAX
7:54p
16h 39m
2 stops
Depart: Sat Jan 10 2015 Return: Sat Jan 31 2015 Trip spans 22 days
JetBlue Airways
JetBlue Airways
BOS
5:45p
STI
9:40p
3h 55m
nonstop
STI
11:39p
BOS
3:30a
3h 51m
nonstop
Depart: Mon Jan 12 2015 Return: Sat Jan 17 2015 Trip spans 6 days
American Airlines
American Airlines
MIA
7:35a
STI
9:37a
2h 02m
nonstop
STI
12:40p
MIA
2:59p
2h 19m
nonstop
Depart: Wed Dec 31 2014 Return: Fri Jan 16 2015 Trip spans 17 days
American Airlines
American Airlines
EWR
12:59a
STI
9:41a
8h 42m
1 stop
STI
12:40p
EWR
7:55p
7h 15m
1 stop
Depart: Tue Apr 7 2015 Return: Fri Apr 10 2015 Trip spans 4 days
Spirit Airlines
Spirit Airlines
LGA
3:45p
STI
9:50p
6h 05m
1 stop
STI
10:37p
LGA
6:00a
7h 23m
1 stop
Depart: Tue Mar 24 2015 Return: Sat Mar 28 2015 Trip spans 5 days
JetBlue Airways
JetBlue Airways
JFK
6:00a
STI
9:42a
3h 42m
nonstop
STI
9:50p
JFK
1:33a
3h 43m
nonstop
Depart: Sun Apr 26 2015 Return: Thu Apr 30 2015 Trip spans 5 days
Spirit Airlines
Spirit Airlines
DFW
1:00p
STI
8:52p
7h 52m
1 stop
STI
10:47p
DFW
6:41a
7h 54m
1 stop
Depart: Mon May 4 2015 Return: Mon May 11 2015 Trip spans 8 days
United
United
DCA
5:30p
STI
9:45a
16h 15m
1 stop
STI
9:50a
DCA
7:00p
9h 10m
1 stop
Depart: Wed Dec 24 2014 Return: Sun Dec 28 2014 Trip spans 5 days
American Airlines
American Airlines
ORD
2:05p
STI
8:41a
18h 36m
2 stops
STI
11:47a
ORD
10:29p
10h 42m
2 stops
Depart: Tue Jun 23 2015 Return: Tue Jun 30 2015 Trip spans 8 days
Delta
Delta
BDL
2:00a
STI
1:50p
11h 50m
2 stops
STI
2:50p
BDL
1:40p
22h 50m
2 stops
Depart: Sat Apr 25 2015 Return: Sat May 2 2015 Trip spans 8 days
United
United
CLT
8:00a
STI
7:50p
11h 50m
1 stop
STI
8:50p
CLT
7:18a
10h 28m
1 stop
Depart: Wed Jun 24 2015 Return: Sat Jul 4 2015 Trip spans 11 days
American Airlines
American Airlines
SEA
8:15p
STI
1:57p
17h 42m
2 stops
STI
5:00a
SEA
9:52p
16h 52m
2 stops
Change your search
Airports
Origin

Charlotte
$547
Seattle
$633
Chicago
$487
Fort Lauderdale
$244
Washington
$460
Miami
$386
New York City
only $422
only $418
West Palm Beach
$380
Orlando
$338
Hartford
$504
Newark
$400
Dallas
$438
Tampa
$360
Jacksonville
$385
Boston
$386
Destination

Santiago de los Caballeros
$244