Santee vacation rentals

KAYAK searches hundreds of travel sites at once for vacation home deals in Santee

Here is why travelers choose KAYAK

Free to useThere are no hidden charges or fees.

Filter your dealsFilter by free cancellation, free breakfast and more.

Millions of reviewsCheck ratings based on millions of real guest reviews.

Recommended by KAYAK
Useful Info
Recommended by KAYAK

Best Santee vacation rentals

Econo Lodge Santee - Santee - Bedroom
Econo Lodge Santee
Santee, SC
5.5Fair(202)
Lodge
Parking
Free Wi-Fi
Pet friendly
$72+
Check availability
Sunsets on Lake Marion - Santee - Living room
Sunsets on Lake Marion
Santee, SC
9.2Wonderful(14)
Condo
Free Wi-Fi
$239+
Check availability
Wyndham Vacation Resorts Lake Marion - Santee - Pool
Wyndham Vacation Resorts Lake Marion
Santee, SC
9.9Wonderful(4)
House
Parking
Free Wi-Fi
Pool
$155+
Check availability
Lovely Condo w/pool, balcony, and lakeside view! - Santee - Patio
Lovely Condo w/pool, balcony, and lakeside view!
Santee, SC
10Wonderful(13)
Condo
$191+
Check availability
Private Dock and Pool Table Lake Marion Getaway - Santee - Living room
Private Dock and Pool Table Lake Marion Getaway
Santee, SC
House
Free Wi-Fi
Pet friendly
$442+
Check availability
Waterfront Condo 3br/3ba- Lake Marion, Ballards Point II, Santee, Sc - Santee - Living room
Waterfront Condo 3br/3ba- Lake Marion, Ballards Point II, Santee, Sc
Santee, SC
9.5Wonderful(29)
Condo
$223+
Check availability
Fisheagle Nature Adventures, Golf Courses, Santee State Park - Santee - Living room
Fisheagle Nature Adventures, Golf Courses, Santee State Park
Santee, SC
House
$498+
Check availability
Lake Marion - Majestic Big Water View! - Santee - Pool
Lake Marion - Majestic Big Water View!
Santee, SC
10Wonderful(9)
Condo
Free Wi-Fi
$240+
Check availability
Wyndham Lake Marion | Three 3br/3ba Suites - Santee - Living room
Wyndham Lake Marion | Three 3br/3ba Suites
Santee, SC
8.0Very good(1)
Condo
Parking
Free Wi-Fi
Pool
$696+
Check availability
\'Penthouse on the big Pond\' Lake Marion, SC at the Club Wyndham Resort\nSleeps 10 - Santee - Pool
\'Penthouse on the big Pond\' Lake Marion, SC at the Club Wyndham Resort\nSleeps 10
Santee, SC
9.5Wonderful(4)
Condo
$211+
Check availability
Enjoy Rural Southern Living in Gated Community Lake access Fishing, Golf, n more - Santee - Building
Enjoy Rural Southern Living in Gated Community Lake access Fishing, Golf, n more
Santee, SC
House
$277+
Check availability
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95! - Santee - Living room
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee, SC
10Wonderful(18)
House
$329+
Check availability
Charming 2 Bedroom Waterfront Lake Marion Condo - Santee - Pool
Charming 2 Bedroom Waterfront Lake Marion Condo
Santee, SC
10Wonderful(4)
Condo
Free Wi-Fi
$275+
Check availability
Fully renovated 1959 lake front cottage. In-ground swimming pool and spa. - Santee - Dining room
Fully renovated 1959 lake front cottage. In-ground swimming pool and spa.
Santee, SC
10Wonderful(5)
House
$494+
Check availability
Quaint 2 bedroom condo - Santee - Pool
Quaint 2 bedroom condo
Santee, SC
Condo
$274+
Check availability
Idyllic Waterfront Escape with Private Boat Dock! - Santee
Idyllic Waterfront Escape with Private Boat Dock!
Santee, SC
9.2Wonderful(21)
House
Free Wi-Fi
$482+
Check availability
Useful Info

Good to know

Low season

High season

Average price (weeknight)

Average price (weekend night)

December
June
$177
$252
Cheapest month to stay with an average 65% drop in price.
Most expensive month to stay with an average 151% rise in price.
Average Sun - Thu price over the last 2 weeks.
Average Fri & Sat price over the last 2 weeks.

KAYAK's top tips for finding Santee vacation rental deals

  • Pet friendly is the most popular vacation rental property amenity in Santee
  • Vacation rentals in Santee are around 91% cheaper than hotels on average. Search here to compare prices for all accommodation types in Santee.
  • The best vacation rental properties in Santee are Waterfront Condo 3br/3ba- Lake Marion, Ballards Point II, Santee, Sc (9.5, 29 reviews), Idyllic Waterfront Escape with Private Boat Dock! (9.2, 21), and Econo Lodge Santee (5.5, 202), based on ratings and reviews from real travelers.
  • If you’re looking for a cheap vacation rental in Santee, you should consider visiting during the low season. The cheapest vacation homes in Santee can be found in December and October.
  • The cheapest night for renting a vacation home in Santee is Saturday. In contrast, the most expensive is Friday.
  • Vacation rentals are a popular choice for both long and short-term stays. KAYAK users usually book their vacation rental in Santee for 5 days.

FAQs when booking a vacation home in Santee

  • What types of vacation rentals are available in Santee?

    There are loads of different property types that you can make your vacation home in Santee. You’ll find cabins, condos, houses and lodges.

  • What are some of the most-loved vacation rentals available in Santee?

    If you’re looking for something special, the vacation rental most loved by KAYAK users is Econo Lodge Santee.

  • Are there any pet-friendly vacation rentals in Santee?

    There are a number of dog and pet-friendly Santee vacation rentals, with around 6% allowing you to bring your pet along with you.

  • How much is a vacation rental in Santee for tonight?

    In the last 72 hours, users have found Santee vacation rentals for tonight for as low as $83. Search here for similar prices

  • How much is a vacation rental in Santee for this weekend?

    In the last 72 hours, users have found Santee vacation rentals for this weekend for as low as $91 per night. Search here for similar prices

  • How can I find vacation rentals near me in Santee?

    Take a look at our vacation rentals map to find the best vacation rental homes near you.

Where to stay in Santee?

Our map will help you find the perfect place to stay in Santee by showing you the exact location of each vacation rental.

Everything you need to know for your stay in Santee