What different cabin options are available?

There are a total of 4 different cabin options; Balcony, inside, oceanview and suite. The most expensive of these is suite at an average price of $1,797/night. The cheapest is inside which costs $1,056/night on average.

What is the most popular itinerary for a cruise along Panama Canal?

There are a range of options and experiences on offer for your next cruise to Panama Canal, depending on factors like how many regions you’d like to visit, and how many times you’d like to port compared to being at sea. The most popular itinerary among KAYAK users was the route; Fort Lauderdale (Port Everglades), Florida, Port of Oranjestad, Aruba, Caribbean, Curacao, Caribbean, Cartagena, Colombia, Cristobal, Panama, Puerto Limon, Costa Rica, Georgetown, Grand Cayman, Cayman Islands, Fort Lauderdale (Port Everglades), Florida.

Panama Canal Cruises: Find the Best Cruises to Panama Canal in 2026

1 Night Southern Caribbean Cruise

Serenade of the Seas

2026-04-18 - 2026-04-19

1 night

Colon, Panama - Cartagena, Colombia

$49/person

Excluding taxes & port fees

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7 Night Southern Caribbean Cruise

Grandeur of the Seas

2026-05-02 - 2026-05-09

7 nights

Tampa, Florida - At sea - Georgetown, Grand Cayman, Cayman Islands - At sea - Port of Oranjestad, Aruba, Caribbean - Willemstad, Curacao - At sea - Colon, Panama

$268/person

Excluding taxes & port fees

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Journeys - 16 Day Panama Canal

Carnival Spirit

2026-04-12 - 2026-04-28

16 nights

Mobile, Alabama - At sea - At sea - At sea - Cartagena, Colombia - Panama Canal, Panama - At sea - Puntarenas, Costa Rica - At sea - At sea - At sea - Cabo San Lucas, Mexico - At sea - At sea - At sea - At sea - Seattle, Washington

$299/person

Excluding taxes & port fees

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10 Night Panama Canal Westward Cruise

Serenade of the Seas

2026-04-25 - 2026-05-05

10 nights

Colon, Panama - Panama Canal, Panama - At sea - Puntarenas, Costa Rica - At sea - Santa Cruz Huatulco, Mexico - At sea - Puerto Vallarta, Mexico - At sea - At sea - Los Angeles, California

$357/person

Excluding taxes & port fees

Interior

12 Night Caribbean Cruise

Caribbean Princess

2026-10-30 - 2026-11-11

12 nights

Fort Lauderdale (Port Everglades), Florida - At sea - At sea - Curacao, Caribbean - At sea - Cartagena, Colombia - At sea - Colon, Panama - Puerto Limon, Costa Rica - At sea - At sea - At sea - Celebration Key, Bahamas - Fort Lauderdale (Port Everglades), Florida

$427/person

Excluding taxes & port fees

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7 Night San Juan To Colon Cruise

Grandeur of the Seas

2027-11-27 - 2027-12-04

7 nights

San Juan, Puerto Rico - Charlotte Amalie, St. Thomas, U.S. Virgin Islands - Philipsburg, St. Maarten - Castries, St. Lucia - At sea - Willemstad, Curacao - At sea - Colon, Panama

$505/person

Excluding taxes & port fees

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7 Night Colon To San Juan Cruise

Grandeur of the Seas

2027-04-24 - 2027-05-01

7 nights

Colon, Panama - At sea - At sea - At sea - Castries, St. Lucia - St. John's, Antigua - Tortola, B.V.I. - San Juan, Puerto Rico

$568/person

Excluding taxes & port fees

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10 Day Caribbean & Panama

Carnival Miracle

2026-10-26 - 2026-11-05

10 nights

Galveston, Texas - At sea - Cozumel, Mexico - At sea - Puerto Limon, Costa Rica - Colon, Panama - At sea - At sea - At sea - At sea - Galveston, Texas

$669/person

Excluding taxes & port fees

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12 Night Caribbean - Southern Cruise

Caribbean Princess

2027-03-28 - 2027-04-09

12 nights

Fort Lauderdale (Port Everglades), Florida - At sea - Georgetown, Grand Cayman, Cayman Islands - Ocho Rios, Jamaica - At sea - Puerto Limon, Costa Rica - Colon, Panama - At sea - Port of Oranjestad, Aruba, Caribbean - At sea - Amber Cove, Dominican Republic - At sea - Fort Lauderdale (Port Everglades), Florida

$709/person

Excluding taxes & port fees

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6 Night Southern Caribbean Cruise

Serenade of the Seas

2026-04-19 - 2026-04-25

6 nights

Cartagena, Colombia - At sea - Willemstad, Curacao - Port of Oranjestad, Aruba, Caribbean - At sea - At sea - Colon, Panama

$767/person

Excluding taxes & port fees

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7 Night Southern Caribbean Cruise

Grandeur of the Seas

2028-01-09 - 2028-01-16

7 nights

Cartagena, Colombia - At sea - At sea - Port of Oranjestad, Aruba, Caribbean - Willemstad, Curacao - At sea - Colon, Panama - Cartagena, Colombia

$769/person

Excluding taxes & port fees

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8 Day Caribbean & Panama

Carnival Spirit

2027-12-04 - 2027-12-12

8 nights

Tampa, Florida - At sea - At sea - Puerto Limon, Costa Rica - Colon, Panama - At sea - Georgetown, Grand Cayman, Cayman Islands - At sea - Tampa, Florida

$769/person

Excluding taxes & port fees

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11 Night Caribbean - Western Cruise

MSC Divina

2026-03-29 - 2026-04-09

11 nights

Miami, Florida - At sea - Ocho Rios, Jamaica - At sea - Port of Oranjestad, Aruba, Caribbean - Cartagena, Colombia - Colon, Panama - At sea - Roatan, Honduras - At sea - Ocean Cay, Bahamas - Miami, Florida

$781/person

Excluding taxes & port fees

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6 Night Southern Caribbean Cruise

Grandeur of the Seas

2028-04-23 - 2028-04-29

6 nights

Cartagena, Colombia - At sea - Port of Oranjestad, Aruba, Caribbean - Willemstad, Curacao - At sea - At sea - Colon, Panama

$788/person

Excluding taxes & port fees

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10 Night Southern Caribbean Cruise

Grandeur of the Seas

2026-11-14 - 2026-11-24

10 nights

Colon, Panama - At sea - Kralendijk, Bonaire, Dutch Antilles - Port of Oranjestad, Aruba, Caribbean - Willemstad, Curacao - At sea - Port of Spain, Trinidad - At sea - At sea - At sea - Colon, Panama

$837/person

Excluding taxes & port fees

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7 Night Southern Caribbean Holiday

Grandeur of the Seas

2027-12-19 - 2027-12-26

7 nights

Cartagena, Colombia - At sea - Willemstad, Curacao - Port of Oranjestad, Aruba, Caribbean - At sea - At sea - Colon, Panama - Cartagena, Colombia

$949/person

Excluding taxes & port fees

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KAYAK’s Insights for Cruises to Panama Canal

Discover seasonal trends, ideal booking windows, and other data-driven tips to plan your cruise to Panama Canal with confidence

What is the cheapest month to take a cruise to Panama Canal?

February is the cheapest month to sail to Panama Canal for cruises with an itinerary of between 4 and 8 port stops.

What is the most popular cruise line operator for Panama Canal sailings?

The 3 most popular operators operating sailings to Panama Canal are; Norwegian, Princess, and Royal Caribbean.

What is the cheapest cruise line to sail with to Panama Canal?

Royal Caribbean is the cheapest out of all of the cruise lines that offer Panama Canal cruises with an average cost of $1,124 for a 4 port itinerary. For an 8 port itinerary, the cheapest cruise line is MSC Cruises with an average cost of $1,380.

What is the cheapest day of the week to depart on a cruise to Panama Canal?

The cheapest day of the week to depart on a cruise with between 4 and 8 port stops is Friday.

What’s the most popular departure point for sailings to Panama Canal?

The most popular departure point for Panama Canal cruise is Miami, Florida. The next most popular is Fort Lauderdale (Port Everglades), Florida.

How many stops do people usually make on a Panama Canal cruise?

Generally, cruises with between 4 and 8 ports are the most popular. For passengers on cruises to Panama Canal, most passengers book a cruise with 5 stops.

What are the most popular cruise ships that sail to Panama Canal?

The most popular cruise ship from all cruises to Panama Canal is Serenade of the Seas.

Low season	High season	Average price (weeknight)	Average price (weekend night)
January	March	$1,566	$1,567
Cheapest month to sail with an average 22% drop in price.	Most expensive month to sail with an average 32% rise in price.	Average weeknight departure price.	Average weekend departure price.

What different cabin options are available?
There are a total of 4 different cabin options; Balcony, inside, oceanview and suite. The most expensive of these is suite at an average price of $1,797/night. The cheapest is inside which costs $1,056/night on average.
What is the most popular itinerary for a cruise along Panama Canal?
There are a range of options and experiences on offer for your next cruise to Panama Canal, depending on factors like how many regions you’d like to visit, and how many times you’d like to port compared to being at sea. The most popular itinerary among KAYAK users was the route; Fort Lauderdale (Port Everglades), Florida, Port of Oranjestad, Aruba, Caribbean, Curacao, Caribbean, Cartagena, Colombia, Cristobal, Panama, Puerto Limon, Costa Rica, Georgetown, Grand Cayman, Cayman Islands, Fort Lauderdale (Port Everglades), Florida.

Try to book around 16 days in advance for the best chance at a below average price.
Miami, Florida is the most popular departure port for all route types taking in a cruise around Panama Canal.
If you're looking to get the most out of Panama Canal cruise and not miss out, most KAYAK users book a 11 days itinerary.