South America cruises

The Latest South America Cruise Deals

Most recommended South America cruises
Serenade of the Seas

1 Night Southern Caribbean Cruise

Serenade of the Seas

2026-04-18 - 2026-04-19

1 night

Colon, Panama - Cartagena, Colombia

$49/person

Excluding taxes & port fees

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MSC Musica

1 Night Grand Voyage Cruise

MSC Musica

2027-04-01 - 2027-04-02

1 night

Santos (Sao Paulo), Brazil - Rio de Janeiro, Brazil

$69/person

Excluding taxes & port fees

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MSC Preziosa

1 Night South America Cruise

MSC Preziosa

2026-04-02 - 2026-04-03

1 night

Santos (Sao Paulo), Brazil - Rio de Janeiro, Brazil

$123/person

Excluding taxes & port fees

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MSC Divina

3 Night Grand Voyage Cruise

MSC Divina

2027-03-14 - 2027-03-17

3 nights

Santos (Sao Paulo), Brazil - Rio de Janeiro, Brazil - At sea - Bahia de Salvador, Brazil

$229/person

Excluding taxes & port fees

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MSC Musica

4 Night Grand Voyage Cruise

MSC Musica

2027-04-01 - 2027-04-05

4 nights

Santos (Sao Paulo), Brazil - Rio de Janeiro, Brazil - At sea - At sea - Maceio, Brazil

$259/person

Excluding taxes & port fees

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Carnival Spirit

Journeys - 16 Day Panama Canal

Carnival Spirit

2026-04-12 - 2026-04-28

16 nights

Mobile, Alabama - At sea - At sea - At sea - Cartagena, Colombia - Panama Canal, Panama - At sea - Puntarenas, Costa Rica - At sea - At sea - At sea - Cabo San Lucas, Mexico - At sea - At sea - At sea - At sea - Seattle, Washington

$299/person

Excluding taxes & port fees

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MSC Virtuosa

6 Night Grand Voyage Cruise

MSC Virtuosa

2027-04-03 - 2027-04-09

6 nights

Santos (Sao Paulo), Brazil - Rio de Janeiro, Brazil - Buzios, Brazil - At sea - Bahia de Salvador, Brazil - At sea - Maceio, Brazil

$389/person

Excluding taxes & port fees

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Costa Serena

3 Night Ocean Cruises Cruise

Costa Serena

2027-04-05 - 2027-04-08

3 nights

Buenos Aires, Argentina - At sea - At sea - Rio de Janeiro, Brazil

$414/person

Excluding taxes & port fees

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MSC Musica

4 Night South America Cruise

MSC Musica

2027-03-15 - 2027-03-19

4 nights

Santos (Sao Paulo), Brazil - Buzios, Brazil - Ilha Grande, Brazil - At sea - Santos (Sao Paulo), Brazil

$469/person

Excluding taxes & port fees

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Costa Diadema

2 Night South America Cruise

Costa Diadema

2026-11-23 - 2026-11-25

2 nights

Santos (Sao Paulo), Brazil - At sea - Itajai, Brazil

$479/person

Excluding taxes & port fees

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MSC Seaview

7 Night South America Cruise

MSC Seaview

2026-03-17 - 2026-03-24

7 nights

Bahia de Salvador, Brazil - Maceio, Brazil - At sea - At sea - Santos (Sao Paulo), Brazil - Buzios, Brazil - At sea - Bahia de Salvador, Brazil

$629/person

Excluding taxes & port fees

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MSC Musica

13 Night Grand Voyage Cruise

MSC Musica

2027-04-02 - 2027-04-15

13 nights

Rio de Janeiro, Brazil - At sea - At sea - Maceio, Brazil - At sea - At sea - At sea - At sea - At sea - At sea - Las Palmas, Gran Canaria, Canary Islands - At sea - At sea - Tarragona, Spain

$703/person

Excluding taxes & port fees

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Grandeur of the Seas

7 Night Southern Caribbean Cruise

Grandeur of the Seas

2026-09-19 - 2026-09-26

7 nights

Colon, Panama - Cartagena, Colombia - At sea - Port of Oranjestad, Aruba, Caribbean - Willemstad, Curacao - At sea - At sea - Colon, Panama

$727/person

Excluding taxes & port fees

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Serenade of the Seas

6 Night Southern Caribbean Cruise

Serenade of the Seas

2026-04-19 - 2026-04-25

6 nights

Cartagena, Colombia - At sea - Willemstad, Curacao - Port of Oranjestad, Aruba, Caribbean - At sea - At sea - Colon, Panama

$767/person

Excluding taxes & port fees

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Grandeur of the Seas

7 Night Southern Caribbean Cruise

Grandeur of the Seas

2028-01-09 - 2028-01-16

7 nights

Cartagena, Colombia - At sea - At sea - Port of Oranjestad, Aruba, Caribbean - Willemstad, Curacao - At sea - Colon, Panama - Cartagena, Colombia

$769/person

Excluding taxes & port fees

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Grandeur of the Seas

6 Night Southern Caribbean Cruise

Grandeur of the Seas

2028-04-23 - 2028-04-29

6 nights

Cartagena, Colombia - At sea - Port of Oranjestad, Aruba, Caribbean - Willemstad, Curacao - At sea - At sea - Colon, Panama

$788/person

Excluding taxes & port fees

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All You Need to Know for Your South America Cruise

Choosing the best time for South America cruises depends on what you are hoping to find. For example, in June, the Galapagos Islands offer cool, dry weather, but at that same time, the Amazon basin is around 90ºF, while snow and ice makes southern Patagonia impassable. This drastic variation in climate means that there is no offseason in South America as a whole, though as a general rule, the summer season is when you will find the continent most hospitable.

The most popular months to visit South America are during the height of summer, which is roughly from December to March, and many tourist destinations will be packed. Rio de Janeiro and Sao Paulo in Brazil are particularly busy, and the world famous Rio de Janeiro carnival in February sees millions of visitors arriving in the city from across the globe.

In the southern part of the continent, the least expensive months to visit are between September to December and between March and June, when the weather is generally colder and there are fewer tourists. You should be prepared to pay higher prices if you want to visit during the peak season months, particularly in major cities such as Rio de Janeiro and Buenos Aires.

There are a number of major international ports in South America, including Buenos Aires in Argentina, Montevideo in Uruguay and Rio de Janeiro in Brazil. On the west coast, Lima in Peru is also a major port, along with Punta Arenas, the gateway to Chilean Patagonia.

South America cruises offer plentiful opportunity for shore excursions. In Argentina, visitors can enjoy a tour of Buenos Aires - the Paris of South America - visit an authentic horse ranch or go kayaking with sea lions. In Brazil, cruise passengers can take in the nightlife of Rio de Janeiro or the grandeur of Sugar Loaf mountain, and on the west coast, visitors can explore the stunning Machalilla National Park in Ecuador or stop to enjoy the breathtaking scenery of Machu Picchu or the Sacred Valley.

There are plenty of options for travelers who want to enjoy the cruises to South American. Avalon Waterways offer a fascinating Treasure of Galapagos cruise along the west coast of the continent that takes in Machu Picchu and the Amazon, and intrepid explorers can try the National Geographic Islander Cruise from Lindblad Expeditions, which stops at Sacred Valley, Quito and the Galapagos Islands.

Silversea cruises are an alternative option for holiday-makers with a slightly higher budget, and offer real extravagance on board. These ships, such as the Silver Cloud Expedition, have a slightly smaller capacity, so guests can rest assured they'll receive special treatment and enjoy the perfect luxury cruise experience.

KAYAK’s Insights for Cruises to South America

Discover seasonal trends, ideal booking windows, and other data-driven tips to plan your cruise to South America with confidence

What is the cheapest month to take a cruise to South America?

November is the cheapest month to sail to South America for cruises with an itinerary of between 4 and 8 port stops.

What is the most popular cruise line operator for South America sailings?

The 3 most popular operators operating sailings to South America are; Princess, Norwegian, and MSC Cruises.

What is the cheapest cruise line to sail with to South America?

Costa is the cheapest out of all of the cruise lines that offer South America cruises with an average cost of $813 for a 4 port itinerary. For an 8 port itinerary, the cheapest cruise line is MSC Cruises with an average cost of $1,780.

What is the cheapest day of the week to depart on a cruise to South America?

The cheapest day of the week to depart on a cruise with between 4 and 8 port stops is Friday.

What’s the most popular departure point for sailings to South America?

The most popular departure point for South America cruise is Fort Lauderdale (Port Everglades), Florida. The next most popular is Miami, Florida.

How many stops do people usually make on a South America cruise?

Generally, cruises with between 4 and 8 ports are the most popular. For passengers on cruises to South America, most passengers book a cruise with 4 stops.

What are the most popular cruise ships that sail to South America?

The most popular cruise ship from all cruises to South America is Caribbean Princess.

Good to know - Essential information for your next South America cruise

Average price (weeknight)

Average price (weekend night)

$1,488
$1,486
Average weeknight departure price.
Average weekend departure price.

FAQs When Booking a cruise to South America

  • What different cabin options are available?

    There are a total of 4 different cabin options; Balcony, inside, oceanview and suite. The most expensive of these is suite at an average price of $1,795/night. The cheapest is inside which costs $1,053/night on average.

  • What is the most popular itinerary for a cruise along South America?

KAYAK’s Top Tips for your next South America cruise

  • Try to book around 12 days in advance for the best chance at a below average price.
  • Fort Lauderdale (Port Everglades), Florida is the most popular departure port for all route types taking in a cruise around South America.
  • If you're looking to get the most out of South America cruise and not miss out, most KAYAK users book a 11 days itinerary.