Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Strasbourg (56% of total searches to Alsace). The next most popular destinations are Basel (27%) and Colmar (15%). Searches for hotels in Mulhouse (2%) are also popular.
KAYAK users have found double rooms in Alsace for as cheap as $30 (Saint-Dié-des-Vosges) in the last 3 days. The average price is $142.