MAD - PTY

$364 Find Cheap Flights from Madrid to Panama City - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Panama City departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Panama City, as well as popular online travel agencies
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41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$756
Typical prices: $850-$698
Iberia
Wed 9/9Sun 9/27
MAD - PTY • Non-stop
Cheapest one-way
$364
Typical prices: $336-$465
Air Europa
Wed 9/2
MAD - PTY • Non-stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
Air Europa Economy Flex adds free changes and preferred seat selection.
Iberia includes two meals and broad entertainment on this long-haul route.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Cheapest • from $756 (round-trip)
Best reviews • 7.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
You can fly direct with Air Europa and Iberia. Average duration is 10h 37m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Avoid delays
Most punctual • 76% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $602 (round-trip)
Shortest trip • 13h 53m (one-way)
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 8% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 14% price drop
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
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Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Madrid to Panama City (MAD-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Madrid to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Madrid to Panama City

Wed, Sep 9 - Sun, Sep 27
Iberia Logo
3:55 pm - 7:35 pm
MAD
-
PTY
10h 40mnonstop
Iberia Logo
9:05 pm - 2:10 pm
PTY
-
MAD
10h 05mnonstop
$756Iberia
Sat, Nov 14 - Tue, Nov 24
Delta Logo
11:55 am - 2:05 pm
MAD
-
PTY
32h 10m
1 stop
Delta Logo
3:30 pm - 9:55 am
PTY
-
MAD
36h 25m
1 stop
$769Delta
Mon, Sep 7 - Tue, Sep 29
Delta Logo
2:35 pm - 12:58 pm
MAD
-
PTY
53h 23m
2 stops
Delta Logo
2:21 pm - 6:20 am
PTY
-
MAD
32h 59m
2 stops
$771Delta
Tue, Sep 29 - Mon, Oct 19
Delta Logo
2:35 pm - 12:56 pm
MAD
-
PTY
29h 21m
2 stops
Delta Logo
2:21 pm - 12:15 pm
PTY
-
MAD
14h 54m
1 stop
$773Delta
Wed, Oct 21 - Thu, Nov 5
Air Europa Logo
3:05 pm - 6:40 pm
MAD
-
PTY
10h 35mnonstop
Air Europa Logo
9:30 pm - 1:05 pm
PTY
-
MAD
9h 35mnonstop
$777Air Europa
Tue, Oct 27 - Sat, Nov 7
Air Europa Logo
3:10 pm - 7:45 pm
MAD
-
PTY
10h 35mnonstop
Air Europa Logo
9:30 pm - 1:05 pm
PTY
-
MAD
9h 35mnonstop
$779Air Europa
Fri, Sep 11 - Sun, Sep 27
Iberia Logo
3:55 pm - 7:35 pm
MAD
-
PTY
10h 40mnonstop
Iberia Logo
9:05 pm - 2:10 pm
PTY
-
MAD
10h 05mnonstop
$780Iberia
Tue, Oct 27 - Mon, Nov 9
Air Europa Logo
3:10 pm - 7:45 pm
MAD
-
PTY
10h 35mnonstop
Air Europa Logo
9:30 pm - 1:05 pm
PTY
-
MAD
9h 35mnonstop
$781Air Europa
Sun, Nov 15 - Mon, Nov 23
Delta Logo
7:30 am - 2:05 pm
MAD
-
PTY
36h 35m
2 stops
Delta Logo
3:30 pm - 9:55 am
PTY
-
MAD
36h 25m
1 stop
$794Delta
Sat, Sep 5 - Tue, Sep 15
Air Europa Logo
3:05 pm - 6:40 pm
MAD
-
PTY
10h 35mnonstop
Air Europa Logo
8:25 pm - 1:15 pm
PTY
-
MAD
9h 50mnonstop
$802Air Europa
Booking Insights

KAYAK's insights & trends for Madrid to Panama City flights

Get data-powered insights and trends into flights from Madrid to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Madrid to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Madrid to Panama City departing in September.

What’s the cheapest day of the week to fly from Madrid to Panama City?

The average price of all round-trip flights from Madrid to Panama City clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Madrid to Panama City, look for departures on Wednesdays and avoid leaving on a Tuesday, as it's usually the priciest day. When flying back from Panama City, Thursday is the cheapest day to fly and Saturday is the most expensive.

What is the cheapest month to fly from Madrid to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madrid to Panama City is April, where tickets cost $734 (return) on average. On the other hand, the most expensive months are December and August, where the average cost of round-trip tickets is $1,101 and $1,051 respectively.

Can I save money by flying with a layover from Madrid to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $813 on average.

How far in advance should I book a flight from Madrid to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Madrid to Panama City, you should book around 3 weeks before departure, which saves you about 8% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 26 weeks before departure.

Expert advice

Expert advice for your flight from Madrid to Panama City

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Ramsey Qubein

Ramsey Qubein

Expert on MAD

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Good to know

Low seasonMay
Cheapest flight$364
Best time to beat the crowds with an average 13% drop in price.
Most popular time to fly with an average 11% increase in price.
Flight from Madrid to Panama City

When to book flights from Madrid to Panama City

Are your dates flexible? Find out the best times to travel from Madrid to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Panama City

  • What is the cheapest flight from Madrid to Panama City?

    In the last 5 days, the lowest price for a flight from Madrid to Panama City was $364 for a one-way ticket and $756 for a round-trip.

  • Do I need a passport to fly between Madrid and Panama City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Madrid and on arrival in Panama City.

  • Which airports will I be using when flying from Madrid to Panama City?

    Madrid airport is called Madrid Barajas and the only airport in Panama City is Panama City Tocumen Intl.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Panama City?

    Iberia, and Copa Airlines offer inflight Wi-Fi service on the Madrid to Panama City flight route.

  • Which aircraft models fly most regularly from Madrid to Panama City?

    The Boeing 787-9 Dreamliner is the aircraft model that flies most regularly on the Madrid to Panama City flight route.

  • Which airline alliances offer flights from Madrid to Panama City?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between Madrid and Panama City, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Madrid to Panama City?

    There are nonstop flights from Madrid to Panama City on a daily basis.

  • Which is the best airline for flights from Madrid to Panama City, Air Europa or Iberia?

    The two airlines most popular with KAYAK users for flights from Madrid to Panama City are Air Europa and Iberia. With an average price for the route of $931 and an overall rating of 7.0, Air Europa is the most popular choice. Iberia is also a great choice for the route, with an average price of $1,024 and an overall rating of 7.0.

  • How does KAYAK find such low prices on flights from Madrid to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Madrid with another airline. Booking your flights between Madrid and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Madrid to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $654 or less one-way and $888 or less round-trip.

Prefer to fly direct from Madrid to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Madrid Barajas to Panama City Tocumen Intl.
Find which airlines fly direct from Madrid Barajas Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Panama City Tocumen Intl

Monday

Air Europa,Iberia

Air Europa,Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa,Iberia

Air Europa,Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa,Iberia

Air Europa,Iberia

Saturday

Air Europa

Air Europa

Sunday

Air Europa,Iberia

Air Europa,Iberia

See more direct flights

Direct returns

Panama City Tocumen Intl to Madrid Barajas

Monday

Air Europa,Iberia

Air Europa,Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa,Iberia

Air Europa,Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa,Iberia

Air Europa,Iberia

Saturday

Air Europa

Air Europa

Sunday

Air Europa,Iberia

Air Europa,Iberia

See more direct flights

Reviews of the top 3 airlines serving from Madrid to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
Air EuropaOverall score based on 619 reviews
6.5Entertainment
7.5Crew
7.1Boarding
6.9Comfort
6.3Food
Airline reviews

The flight was long but everything went well. Crew was helpful and very attentive. Food was good and the entertainment options were many.

10.0 ExcellentGreg, Apr 2026
MAD - JFK
Read more Air Europa reviews

The flight was long but everything went well. Crew was helpful and very attentive. Food was good and the entertainment options were many.

My long-haul flight experience with this airline was not very pleasant. Earphones were paid, and no eye mask or other amenities were provided. The meals were served in cardboard boxes with plastic cutlery. The restroom was unclean and ran out of toilet paper. However, the boarding process was smooth and well organized.

We experienced a delay of almost two hours before takeoff. For a flight of more than 10 hours, sitting on the runway for two hours is quite exhausting. The airline did nothing to attend to the passengers during that time. We were not given any courtesy drinks or snacks—only the bare minimum during the flight. The crew seemed very apologetic, but apparently they have restrictions imposed by the airline, because despite their friendliness, they provided strictly what was necessary and, of course, everything else was for sale. However, after a two-hour delay, one would expect at least complimentary beverages. In addition to this, the space between the rows of seats is inhumanely narrow. Air Europa should review this for such long flights and be a bit more considerate and humane with its customers.

I flew in business a couple of months ago, it was great, tried again in economy, it is the cramped seat I have ever been into, for an overseas flight across the atlantic it is inhumane to put passengers in such cramped space. Other than that, everything ok. Took a second flight from Madrid to London, also economy and it was roomy and perfect.

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

There was no water in one of the sinks in the executive area, which is unacceptable as we could not wash our hands after using the restroom

Like I said the experience was mediocre. Nothing special about this airline.

This flight was delayed by more than an hour. The seats are uncomfortable ans do not recline properly. I prepurchased a wifi pass, but wifi was not working on this flight at all. The food was bland.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

I was not allowed to cancel the flight, customer service is atrocious

Overall it was okay. Just the lost baggage and how they are handling it

Puddle-hopper. Quick-ish flight. Don’t expect to have much/any in-flight entertainment (movies/TV, etc).

Worst flight I ever experienced, what was supposed to a 7 hour flight ended being 13 hours on a plane with no ac and the worst cabin I have ever seen. Never again.

Horrible seat at the back. Crew was very kind. Packed plane. Wordy pilot bragging about Iberia being punctual when many of us came from Alicante flight that was delayed an hour and many lost connection and we lost our luggage. Still waiting for it

Excellent plane, 787. Very good seat and additional stuff they provide. Good food. Very good staff.

Excellent except WiFi is a Must on Biz class 10 hour flight ! Didn’t work entire flight. SW doesn’t do that.

Excellent crew, food and service. Boarding via bus is always a pain but overall really good

Stewardess was not attentive at all asked for a bottle of water never came by 15 minutes later I asked her she said that she forgot there was only 12 people in first class and two stewardess unacceptable I ordered the fish was the last person to order. They said that they did not have any had to have a different item pasta at the inside of it because I was diabetic. Worst experience I ever had will never travel this airline again.

It’s got the tightest seats of any airline - my knees were smashed for 3 hours - absolutely awful.

Flight was fine - however my husband's checked in case was damaged, and mine still has not arrived

The airline did not allow enough time for the Columbia checkpoint

The employees at the gate were not communicating, they preferred to give the upgrade to pilots and not to the elite passengers Every flight I more disappointing, clients shooed be priority instead of other employees even if they are pilots, there was plenty room for pilots in economy

This was my first time flying with you guys and my very last! This was the most horrible experience!!! There was not even tv in the plane! How cheap can this airline be!!! I paid so much for my suitcase!!! I would never fly with this airline again! The crew are very rude!

After boarding, there was a small issue with the aircraft which caused a delay of about 45 minutes. During boarding and while passengers were being seated, the plane was being refueled. There were also a lot of unusual noises during the flight, which was not very reassuring. In addition, there was no WiFi or entertainment available.

Overall, the flight went well and the service was good. However, there was a very frightening moment during landing in Bogotá. Just as the plane was about to touch down, it suddenly went back up into the air. The aircraft was not descending straight and seemed to move left and right, which made the situation feel unstable. This was quite scary. After going back up, the plane circled for about 15 minutes before attempting to land again. Although I understand that safety always comes first and situations like this can happen, it was still a shocking experience for passengers.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

I upgraded to businesses class. Because of that the flight was comfortable.

only a bag of chips and a bottle of water in business class was served

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Everything you need to know for your flight from Madrid to Panama City

Information on your arrival and departure airports