MAD - PTY

$468 Find Cheap Flights from Madrid to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Panama City departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$799
Typical prices: $821-$1,483
Delta
Mon 11/24Wed 12/3
MAD - PTY • 2 stops
Cheapest non-stop
$811
Typical prices: $652-$755
Air Europa
Mon 2/9Thu 2/19
MAD - PTY • Non-stop
Our travelers' advice
AI-generated summary based on content written by travel experts
Air Europa's Economy Flex allows changes without penalty.
Use authorized taxi stands at PTY for fixed rates.
Expert advice
Expert advice
Expert advice
Expert advice
Top airlines
Delta
Cheapest • from $799 (round-trip)
Air Europa
Best reviews • 7.0 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to book
6 weeks
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 10% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 16% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Madrid to Panama City (MAD-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Madrid to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Madrid to Panama City

Mon, Nov 24 - Wed, Dec 3
Delta Logo
6:00 am - 2:12 pmMAD-PTY
38h 12m2 stops
Delta Logo
3:46 pm - 8:00 amPTY-MAD
58h 14m2 stops
$799Delta
Find Deal
Tue, Mar 24 - Sun, Apr 12
Delta Logo
10:05 am - 12:55 pmMAD-PTY
32h 50m1 stop
Delta Logo
2:20 pm - 7:50 amPTY-MAD
34h 30m2 stops
$800Delta
Find Deal
Sun, Nov 23 - Wed, Dec 3
Delta Logo
10:00 am - 2:12 pmMAD-PTY
58h 12m2 stops
Delta Logo
3:46 pm - 8:00 amPTY-MAD
58h 14m2 stops
$801Delta
Find Deal
Thu, Nov 27 - Wed, Dec 3
Delta Logo
1:05 pm - 2:12 pmMAD-PTY
31h 07m2 stops
Delta Logo
3:46 pm - 8:00 amPTY-MAD
34h 14m2 stops
$807Delta
Find Deal
Mon, Feb 9 - Fri, Feb 20
Air Europa Logo
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
Air Europa Logo
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
$811Air Europa
Find Deal
Thu, Feb 19 - Sat, Mar 7
Air Europa Logo
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
Air Europa Logo
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
$812Air Europa
Find Deal
Sun, Mar 8 - Sat, Mar 21
Air Europa Logo
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
Air Europa Logo
9:30 pm - 1:05 pmPTY-MAD
9h 35mnonstop
$813Air Europa
Find Deal
Wed, Mar 4 - Sun, Mar 29
Air Europa Logo
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
Air Europa Logo
8:25 pm - 1:15 pmPTY-MAD
9h 50mnonstop
$817Air Europa
Find Deal
Tue, Mar 10 - Sat, Mar 28
Air Europa Logo
3:10 pm - 7:45 pmMAD-PTY
10h 35mnonstop
Air Europa Logo
9:30 pm - 1:55 pmPTY-MAD
9h 25mnonstop
$818Air Europa
Find Deal
Wed, Mar 25 - Sat, Apr 11
Multiple Airlines Logo
6:00 am - 4:30 pmMAD-PTY
16h 30m1 stop
Multiple Airlines Logo
7:55 pm - 11:10 pmPTY-MAD
20h 15m1 stop
$819Multiple Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Madrid to Panama City flights

Get data-powered insights and trends into flights from Madrid to Panama City to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Madrid to Panama City?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Madrid to Panama City departing in November.

What’s the cheapest day of the week to fly from Madrid to Panama City?

The average price of all round-trip flights from Madrid to Panama City clicked on KAYAK for each day over the last 12 months.

If you are looking for a flight deal from Madrid to Panama City, look for departures on Wednesdays and avoid leaving on a Thursday, as it's usually the priciest day. When flying back from Panama City, Tuesday is the cheapest day to fly and Sunday is the most expensive.

What is the cheapest month to fly from Madrid to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madrid to Panama City is March, where tickets cost $682 (return) on average. On the other hand, the most expensive months are December and August, where the average cost of round-trip tickets is $1,074 and $1,005 respectively.

Can I save money by flying with a layover from Madrid to Panama City?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $677 on average.

How far in advance should I book a flight from Madrid to Panama City?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Panama City, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Madrid to Panama City, you should book around 6 weeks before departure, which saves you about 10% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Expert advice

Expert advice for your flight from Madrid to Panama City

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Air Europa

Air Europa offers speedy Wi-Fi and two meal services for premium and business fares.


Air Europa's Economy Flex allows changes without penalty and offers preferred seat selection.

Iberia

Iberia's business class offers all-aisle access and private suites on A350-900 aircraft.


Iberia provides two meals and a wide range of in-flight entertainment on long-haul flights.

Airports
MAD

For VAT tax refunds, complete forms in-store and validate at the airport before check-in. Refunds are mostly electronic, sometimes cash.

PTY

To avoid taxi haggling, use authorized taxi stands at PTY for fixed rates. Confirm express highway use to Panama City.

Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff

Laura Ratliff

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Read more
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more
Ramsey Qubein

Ramsey Qubein

Expert on MAD

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Mark Chesnut

Mark Chesnut

Expert on PTY

Mark Chesnut

Mark Chesnut

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Read more

Good to know

Low seasonMay
Cheapest flight$468
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 32% increase in price.
Flight from Madrid to Panama City

When to book flights from Madrid to Panama City

Are your dates flexible? Find out the best times to travel from Madrid to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Panama City

  • What is the cheapest flight from Madrid to Panama City?

    In the last 3 days, the lowest price for a flight from Madrid to Panama City was $468 for a one-way ticket and $799 for a round-trip.

  • Do I need a passport to fly between Madrid and Panama City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Madrid and on arrival in Panama City.

  • Which airports will I be using when flying from Madrid to Panama City?

    Madrid airport is called Madrid Barajas and the only airport in Panama City is Panama City Tocumen Intl.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Panama City?

    Iberia, and KLM offer inflight Wi-Fi service on the Madrid to Panama City flight route.

  • Which aircraft models fly most regularly from Madrid to Panama City?

    The Boeing 787-9 Dreamliner is the aircraft model that flies most regularly on the Madrid to Panama City flight route.

  • Which airline alliances offer flights from Madrid to Panama City?

    Star Alliance, oneworld, and SkyTeam are the airline alliances operating flights between Madrid and Panama City, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Madrid to Panama City?

    There are nonstop flights from Madrid to Panama City on a daily basis.

  • Which is the best airline for flights from Madrid to Panama City, Air Europa or Iberia?

    The two airlines most popular with KAYAK users for flights from Madrid to Panama City are Air Europa and Iberia. With an average price for the route of $883 and an overall rating of 7.0, Air Europa is the most popular choice. Iberia is also a great choice for the route, with an average price of $901 and an overall rating of 7.0.

  • How does KAYAK find such low prices on flights from Madrid to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Madrid with another airline. Booking your flights between Madrid and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Madrid to Panama City

  • Looking for a cheap flight? 25% of our users found flights on this route for $642 or less one-way and $1,086 or less round-trip.

Prefer to fly direct from Madrid to Panama City?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Madrid Barajas to Panama City Tocumen Intl.
Find which airlines fly direct from Madrid Barajas Airport to Panama City Tocumen Intl Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Panama City Tocumen Intl

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa

Air Europa

See more direct flights

Direct returns

Panama City Tocumen Intl to Madrid Barajas

Monday

Air Europa, Iberia

Air Europa, Iberia

Tuesday

Air Europa

Air Europa

Wednesday

Air Europa, Iberia

Air Europa, Iberia

Thursday

Air Europa

Air Europa

Friday

Air Europa

Air Europa

Saturday

Air Europa, Iberia

Air Europa, Iberia

Sunday

Air Europa

Air Europa

See more direct flights

Reviews of the top 3 airlines serving from Madrid to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
Air EuropaOverall score based on 569 reviews
7.0Comfort
7.5Crew
7.1Boarding
6.3Food
6.6Entertainment
Airline reviews

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

8.0 ExcellentJustin, Sep 2025MAD - AGP
Read more Air Europa reviews

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

My luggage is lost and nowhere to be found, no response from airline

Boarding was a shitshow. Had to bus to the gate. No separate bus and boarding process for Business Class.

The plane was very old, no power outlets. We also had to wait a long time to board. They kept moving us to different lines before we actually could step foot on the plane. We ended up being delayed an hour but we were never told or informed for any reason. After the meal I asked for a coffee which the flight attendant forgot and I had to ask again. Overall not the worst but not the best experience.

Need to pay for headsets, water, or any extra except air to breath.

Sitting space was very tight and I am not big or fat (I am 5'10" 178 Lb), so eating was very challenging. The rest was good.

Sitting space was very tight, so eating was difficult. But everything else was good.

12 hours flight. Only one meal, not enough food. At the galley only water during the flight. Lavatories not clean. Headsets at extra cost.

Need to pay for a cup of water. No food. Need to pay for headsets.

Everything should improve! Service like a low cost but prices like a premium airline. Crew in general with bad manners arguing for everything. You pay for priority access but then they use buses, so your loose your advantage to put your carry on first. That was the purpose for paying for priority. Bording is a nightmare, people accessing the plane for bothering doors, front and rear, no matter which line do you have.

I've taken British Airways before and it has been great. On this trip to Spain and Portugal we had two BA flights. On both flights we were taken by bus from the terminal out to the plane on the tarmac. There were many older folks on these flights, and to ask people in their 70s to lug their carry-on and personal items up the long mobile staircase to the plane entrance, is very disturbing. I won't be taking British Airways in the future. Many people on these flights were very unhappy.

why can't planes be boarded from back to front?? everything was great otherwise

We flew into Barcelona and the plane was so cramped and very uncomfortable and dirty. But we flew out of Madrid and that plane was much better. Would fly Iberia again.

For what we are willing to pay for international air travel, our experience was very good. We had no problem checking in, we had very little wait time at the AA counter in Madrid, and the staff in Madrid were very helpful. The flight crew was helpful and courteous, the plane was on the newer side, and our assigned seats were together without us needing to purchase them. The flight took off on time and arrived early. Overall, it was a pleasant experience or as much as could be expected in economy for almost 10 hours.

Terrible customer service. I booked business class and the counter agent didn’t bother asking me about any choice or preferred seat, basically assigned me that last seat and couldn’t even answer if it was a business class seat. Also iberia lost my suitcase on my flight from JFK to MAD with the layover in BCN. Useless customer service at the counter. Thank goodness I happened to check the baggage claim area of the next flight in…there it was.

Boarding was easy, the flight left on time and even landed 20 minutes early. The food was plentiful and really good! The crew was kind & helpful. Overall it was an exceptional experience!

The flight was safe, confortable and convenient. Thank you. I hope to come back soon!

Delayed. Mismanagement of gate lines. Passengers arguing with eachother as a result of lack of organization by airline. Avoid this airline.

Because the plane was delayed from Madrid to LAX, we missed our connecting flight to Malaga. Iberia offered to book us a hotel room but I needed to be in Malaga that evening. I ended up buying train tickets to Malaga from Madrid. I also feel Iberia should compensate me for the cost of the train tickets because they didn't meet their travel obligation.

Terrible. Won’t fly again. Boarding was an issue. Took TWO hours to “find” my confirmed reservation. Crew at desk was super rude and unconcerned. Was not escorted through despite delay on their end. Almost missed fight and luggage arrived one day late…. Which I had to pick up by cab or wait even longer (not reimbursed).

Did not fly with Pakistan International Airlines. Have never flown with Pakistan International Airlines.

Boarding, crew were excellent, food was ok and entertainment need to improve

Luggage lost and nowhere to be found, no response from either airline regarding my bag

The seats were uncomfortable and barely reclined at all. Very little leg room despite being business class. The crew was friendly and the food was good. Had to use my own phone for in-flight entertainment.

Not what it used to be. The sale of food makes them look greedy!

Avianca is not what it used to be. So disappointing

The incoming plane was late and no information was shared. They even announced we would board in 10 muntes 40 minutes prior to the plane arriving, and the website said until takeoff that we had taken off an hour earlier

Boarding was excessively slow. They do it by groups in a way that it doesn’t make sense. After business class , ppl that need assistance and any other priority group they should have ppl board from the back to the front. First rows 20+. Then 15+. Then 10, etc. having ppl sitting in the back board last makes no sense. The libe backame long as soon as ppl on rows 10 or so where told to board. The line went all the way up the ramp and tunnel for 25 mins.

Seats are very tight even in Plus, no complimentary snacks or beverage

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

Everything you need to know for your flight from Madrid to Panama City

Information on your arrival and departure airports