MAD - VVI

$388 Find Cheap Flights from Madrid to Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Santa Cruz de la Sierra departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$963
Typical prices: $1,130-$845
Avianca
Wed 11/11Mon 11/23
MAD - VVI • 1 stop
Cheapest non-stop
$1,005
Typical prices: $1,222-$867
Air Europa
Mon 8/31Tue 9/22
MAD - VVI • Non-stop
Nonstop flights
Mon, Wed, Fri, Sat, Sun
You can fly direct with Air Europa and BoA. Average duration is 11h 07m
Direct flights
Direct flights
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Direct flights
Direct flights
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Top airlines
Cheapest • from $963 (round-trip)
Best reviews • 7.0 score
Airline reviews
Airline reviews
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Airline reviews
Airline reviews
+1
Top layover airports
Cheapest • Avg $845 (round-trip)
Shortest trip • 17h 51m (one-way)
Insights
Insights
Insights
Insights
Avoid delays
Most punctual • 61% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 6 weeks in advance save around 12% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 20% price drop
Most popular
Good to know
Good to know
+1
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Good to know
Good to know
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Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Cruz de la Sierra!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Madrid to Santa Cruz de la Sierra (MAD-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Madrid to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Madrid to Santa Cruz de la Sierra

Wed, Nov 11 - Mon, Nov 23
Avianca Logo
7:20 am - 2:35 am
MAD
-
VVI
24h 15m
1 stop
Avianca Logo
3:40 am - 10:40 am
VVI
-
MAD
26h 00m
2 stops
$963Avianca
Fri, Oct 23 - Sun, Nov 22
Avianca Logo
8:10 am - 2:30 am
MAD
-
VVI
24h 20m
1 stop
Avianca Logo
3:40 am - 11:20 pm
VVI
-
MAD
14h 40m
1 stop
$968Avianca
Sun, Aug 30 - Tue, Sep 22
Avianca Logo
11:05 am - 2:30 am
MAD
-
VVI
21h 25m
1 stop
Avianca Logo
3:35 am - 12:20 am
VVI
-
MAD
14h 45m
1 stop
$969Avianca
Tue, Sep 8 - Tue, Feb 9
Avianca Logo
8:10 am - 2:30 am
MAD
-
VVI
24h 20m
1 stop
Avianca Logo
3:40 am - 11:20 pm
VVI
-
MAD
14h 40m
1 stop
$972Avianca
Sat, Sep 12 - Tue, Oct 13
Avianca Logo
5:20 pm - 2:30 am
MAD
-
VVI
15h 10m
1 stop
Avianca Logo
3:35 am - 3:00 pm
VVI
-
MAD
29h 25m
2 stops
$973Avianca
Sun, Aug 30 - Tue, Sep 22
Avianca Logo
8:05 pm - 2:30 am
MAD
-
VVI
36h 25m
2 stops
Avianca Logo
3:35 am - 12:20 am
VVI
-
MAD
14h 45m
1 stop
$977Avianca
Mon, Oct 19 - Fri, Oct 30
Avianca Logo
5:20 pm - 2:30 am
MAD
-
VVI
15h 10m
1 stop
Avianca Logo
3:40 am - 11:20 pm
VVI
-
MAD
14h 40m
1 stop
$978Avianca
Wed, Oct 28 - Fri, Nov 13
Avianca Logo
7:20 am - 2:35 am
MAD
-
VVI
24h 15m
1 stop
Avianca Logo
3:40 am - 3:00 pm
VVI
-
MAD
30h 20m
2 stops
$1,001Avianca
Mon, Aug 31 - Tue, Sep 22
Air Europa Logo
11:35 pm - 4:50 am
MAD
-
VVI
11h 15mnonstop
Air Europa Logo
12:20 pm - 5:10 am
VVI
-
MAD
10h 50mnonstop
$1,005Air Europa
Mon, Sep 7 - Tue, Feb 9
Avianca Logo
2:10 am - 2:30 am
MAD
-
VVI
30h 20m
2 stops
Avianca Logo
3:40 am - 11:20 pm
VVI
-
MAD
14h 40m
1 stop
$1,010Avianca
Booking Insights

KAYAK's insights & trends for Madrid to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Madrid to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Madrid to Santa Cruz de la Sierra?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Madrid to Santa Cruz de la Sierra departing in November.

What’s the cheapest day of the week to fly from Madrid to Santa Cruz de la Sierra?

The average price of all round-trip flights from Madrid to Santa Cruz de la Sierra clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Santa Cruz de la Sierra on a Sunday, as we generally find the cheapest rates on that day for this route. On the other hand, Monday is the most expensive day to fly from Madrid to Santa Cruz de la Sierra. For your return ticket, we recommend flying on a Sunday and avoiding Saturdays for the best deals.

What is the cheapest month to fly from Madrid to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madrid to Santa Cruz de la Sierra is April, where tickets cost $845 (return) on average. On the other hand, the most expensive months are July and December, where the average cost of round-trip tickets is $1,453 and $1,363 respectively.

Can I save money by flying with a layover from Madrid to Santa Cruz de la Sierra?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $821 on average.

How far in advance should I book a flight from Madrid to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Madrid to Santa Cruz de la Sierra, you should book around 6 weeks before departure, which saves you about 12% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 24 weeks before departure.

Expert advice

Expert advice for your flight from Madrid to Santa Cruz de la Sierra

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Good to know

Low seasonJanuary
Cheapest flight$388
Best time to beat the crowds with an average 3% drop in price.
Most popular time to fly with an average 22% increase in price.
Flight from Madrid to Santa Cruz de la Sierra

When to book flights from Madrid to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Madrid to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Santa Cruz de la Sierra

  • What is the cheapest flight from Madrid to Santa Cruz de la Sierra?

    In the last 5 days, the lowest price for a flight from Madrid to Santa Cruz de la Sierra was $388 for a one-way ticket and $963 for a round-trip.

  • Do I need a passport to fly between Madrid and Santa Cruz de la Sierra?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Madrid and on arrival in Santa Cruz de la Sierra.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Santa Cruz de la Sierra?

    Iberia, LATAM Airlines, and Qatar Airways offer inflight Wi-Fi service on the Madrid to Santa Cruz de la Sierra flight route.

  • Which aircraft models fly most regularly from Madrid to Santa Cruz de la Sierra?

    The Airbus A330-200 is the aircraft model that flies most regularly on the Madrid to Santa Cruz de la Sierra flight route.

  • Which airline alliances offer flights from Madrid to Santa Cruz de la Sierra?

    oneworld, and Star Alliance are the airline alliances operating flights between Madrid and Santa Cruz de la Sierra, with oneworld being the most commonly used for this route.

  • On which days can I fly direct from Madrid to Santa Cruz de la Sierra?

    You can catch a nonstop flight from Madrid to Santa Cruz de la Sierra on on Monday, Wednesday, Friday, Saturday, and Sunday.

  • Which is the best airline for flights from Madrid to Santa Cruz de la Sierra, Iberia or BoA?

    The two airlines most popular with KAYAK users for flights from Madrid to Santa Cruz de la Sierra are Iberia and BoA. With an average price for the route of $1,201 and an overall rating of 7.0, Iberia is the most popular choice. BoA is also a great choice for the route, with an average price of $1,301 and an overall rating of 6.8.

  • How does KAYAK find such low prices on flights from Madrid to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Madrid with another airline. Booking your flights between Madrid and VVI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Madrid to Santa Cruz de la Sierra

  • Looking for a cheap flight? 25% of our users found flights on this route for $433 or less one-way and $1,208 or less round-trip.

Prefer to fly direct from Madrid to Santa Cruz de la Sierra?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl.
Find which airlines fly direct from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl

Monday

Air Europa,BoA

Air Europa,BoA

Wednesday

Air Europa,BoA

Air Europa,BoA

Friday

BoA

BoA

Saturday

Air Europa

Air Europa

Sunday

Air Europa,BoA

Air Europa,BoA

See more direct flights

Direct returns

Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas

Monday

Air Europa,BoA

Air Europa,BoA

Tuesday

Air Europa,BoA

Air Europa,BoA

Thursday

Air Europa,BoA

Air Europa,BoA

Saturday

Air Europa,BoA

Air Europa,BoA

Sunday

BoA

BoA

See more direct flights

Reviews of the top 3 airlines serving from Madrid to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.0
IberiaOverall score based on 3237 reviews
6.7Comfort
7.7Crew
7.2Boarding
6.6Entertainment
6.3Food
Airline reviews

Overall it was okay. Just the lost baggage and how they are handling it

2.0 MediocreJoe, Jun 2026
MAD - FLR
Read more Iberia reviews

Overall it was okay. Just the lost baggage and how they are handling it

Puddle-hopper. Quick-ish flight. Don’t expect to have much/any in-flight entertainment (movies/TV, etc).

Worst flight I ever experienced, what was supposed to a 7 hour flight ended being 13 hours on a plane with no ac and the worst cabin I have ever seen. Never again.

Horrible seat at the back. Crew was very kind. Packed plane. Wordy pilot bragging about Iberia being punctual when many of us came from Alicante flight that was delayed an hour and many lost connection and we lost our luggage. Still waiting for it

Excellent plane, 787. Very good seat and additional stuff they provide. Good food. Very good staff.

Excellent except WiFi is a Must on Biz class 10 hour flight ! Didn’t work entire flight. SW doesn’t do that.

Excellent crew, food and service. Boarding via bus is always a pain but overall really good

Stewardess was not attentive at all asked for a bottle of water never came by 15 minutes later I asked her she said that she forgot there was only 12 people in first class and two stewardess unacceptable I ordered the fish was the last person to order. They said that they did not have any had to have a different item pasta at the inside of it because I was diabetic. Worst experience I ever had will never travel this airline again.

It’s got the tightest seats of any airline - my knees were smashed for 3 hours - absolutely awful.

Flight was fine - however my husband's checked in case was damaged, and mine still has not arrived

Unfortunately had horrible experience Originally booked business class from La Paz to Miami Flight was delayed for 2 hours with no clear explanation

Our flight was canceled and we were put on a different flight, but we were never notified of the change until we checked in. BOA provides no beverage service during the flight and there is no in-flight entertainment. Airline staff tried to tell us that we were not allowed one personal item and one carry-on bag per person, but instead that we were only allowed one item aboard per person, which contradicts their written luggage policy. Airline staff also claimed that a car seat counted against our carry-on allowance, even though our child had his own ticket and is required to use a car seat on board per airline policy.

The crew was great, professional and polite. Good meal too. The flight was full and we departed on time out of Miami. I did feel cramped in my seat for the long overnight flight, which made it hard to sleep

This airline and their crew is so professional and kind, the trip was short and easy.

It was a very smooth process. Everything about the Airline like a well oiled machine.

Muy horrible experiencia, cambiaron dos veces la hora del vuelo resultando en una espera exagerada. No dan información oportuna. Abordadnos el avión retrasado el vuelo y esperamos dentro del avión por 35’ más mientras subían como 6 carros de cajas al avión. Muy mala logística y servicio.

6 horas de retraso en el vuelo sin ninguna explicación por parte de la aerolínea.

Always late, the service is a sandwich, no comfort at all…

They had a problem with their air conditioning system and we almost had heat strokes because they blasted HEATED AIR for almost 40 minutes and there was literally no air. This is the worst airline in Bolivia. Can't believe we have no other options sometimes.

BOA is truly the worst airline in Bolivia. It's a shame we sometimes need to use it cause we have no more options.

This was my first time flying with you guys and my very last! This was the most horrible experience!!! There was not even tv in the plane! How cheap can this airline be!!! I paid so much for my suitcase!!! I would never fly with this airline again! The crew are very rude!

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Provide free food and drinks on an international flight. Add updated head rests

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

Everything you need to know for your flight from Madrid to Santa Cruz de la Sierra

Information on your arrival and departure airports