MAD - VVI

$372 Find Cheap Flights from Madrid to Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Santa Cruz de la Sierra departing on 3/9. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$733
Typical prices: $833-$1,014
Avianca
Sun 4/12Sat 4/25
MAD - VVI • 1 stop
Cheapest non-stop
$821
Typical prices: $842-$1,033
Iberia
Sun 4/26Tue 5/12
MAD - VVI • Non-stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
Air Europa offers speedy Wi-Fi for all needs.
Iberia serves Spanish cuisine with two meals onboard.
Expert advice
Expert advice
Expert advice
Expert advice
Nonstop flights
5 days a week
Mon, Wed, Fri, Sat, Sun
You can fly direct with Air Europa and BoA. Average duration is 11h 05m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top airlines
Avianca
Cheapest • from $733 (round-trip)
Air Europa
Best reviews • 6.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top layover airports
Bogotá (BOG)
Cheapest • Avg $1,072 (round-trip)
Bogotá (BOG)
Shortest trip • 19h 27m (one-way)
Insights
Insights
Insights
Insights
Avoid delays
Air Europa
Most punctual • 60% on-time
Night flights
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 13% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 20% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Cruz de la Sierra!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Madrid to Santa Cruz de la Sierra (MAD-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Madrid to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Madrid to Santa Cruz de la Sierra

Sun, Apr 12 - Sat, Apr 25
Avianca Logo
8:10 am - 2:30 am
MAD
-
VVI
24h 20m
1 stop
Avianca Logo
3:35 am - 9:05 am
VVI
-
MAD
23h 30m
1 stop
$733Avianca
Thu, Aug 27 - Fri, Oct 2
Avianca Logo
2:20 am - 2:30 am
MAD
-
VVI
30h 10m
1 stop
Avianca Logo
3:35 am - 9:05 am
VVI
-
MAD
23h 30m
1 stop
$739Avianca
Sun, Apr 12 - Sun, Apr 26
Avianca Logo
11:05 am - 2:30 am
MAD
-
VVI
21h 25m
1 stop
Avianca Logo
3:35 am - 12:20 am
VVI
-
MAD
14h 45m
1 stop
$743Avianca
Tue, May 5 - Thu, May 21
Avianca Logo
5:20 pm - 2:30 am
MAD
-
VVI
15h 10m
1 stop
Avianca Logo
3:35 am - 2:05 pm
VVI
-
MAD
28h 30m
1 stop
$744Avianca
Thu, Mar 19 - Mon, Apr 20
Avianca Logo
1:20 am - 2:35 am
MAD
-
VVI
30h 15m
1 stop
Avianca Logo
3:35 am - 9:05 am
VVI
-
MAD
23h 30m
1 stop
$752Avianca
Fri, Mar 20 - Mon, Apr 20
Avianca Logo
10:50 am - 2:35 am
MAD
-
VVI
20h 45m
1 stop
Avianca Logo
3:35 am - 9:05 am
VVI
-
MAD
23h 30m
1 stop
$759Avianca
Sun, May 10 - Wed, Jun 10
Avianca Logo
8:10 am - 2:30 am
MAD
-
VVI
24h 20m
1 stop
Avianca Logo
3:35 am - 12:20 am
VVI
-
MAD
14h 45m
1 stop
$763Avianca
Wed, Mar 18 - Tue, Sep 29
Avianca Logo
10:50 am - 2:35 am
MAD
-
VVI
20h 45m
1 stop
Avianca Logo
3:35 am - 12:20 am
VVI
-
MAD
14h 45m
1 stop
$764Avianca
Fri, Apr 10 - Mon, May 25
Avianca Logo
5:20 pm - 2:30 am
MAD
-
VVI
15h 10m
1 stop
Avianca Logo
3:35 am - 9:05 am
VVI
-
MAD
23h 30m
1 stop
$765Avianca
Mon, Mar 30 - Mon, Apr 13
Avianca Logo
7:40 am - 2:30 am
MAD
-
VVI
24h 50m
2 stops
Avianca Logo
3:35 am - 12:20 am
VVI
-
MAD
14h 45m
1 stop
$779Avianca
Booking Insights

KAYAK's insights & trends for Madrid to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Madrid to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Madrid to Santa Cruz de la Sierra?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Madrid to Santa Cruz de la Sierra departing in April.

What’s the cheapest day of the week to fly from Madrid to Santa Cruz de la Sierra?

The average price of all round-trip flights from Madrid to Santa Cruz de la Sierra clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Santa Cruz de la Sierra on a Friday, as we generally find the cheapest rates on that day for this route. On the other hand, Sunday is the most expensive day to fly from Madrid to Santa Cruz de la Sierra. For your return ticket, we recommend flying on a Thursday and avoiding Saturdays for the best deals.

What is the cheapest month to fly from Madrid to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madrid to Santa Cruz de la Sierra is March, where tickets cost $869 (return) on average. On the other hand, the most expensive months are July and August, where the average cost of round-trip tickets is $1,426 and $1,391 respectively.

Can I save money by flying with a layover from Madrid to Santa Cruz de la Sierra?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $848 on average.

How far in advance should I book a flight from Madrid to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Madrid to Santa Cruz de la Sierra, you should book around 3 weeks before departure, which saves you about 13% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 12 weeks before departure.

Expert advice

Expert advice for your flight from Madrid to Santa Cruz de la Sierra

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Good to know

Low seasonMay
Cheapest flight$372
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly with an average 24% increase in price.
Flight from Madrid to Santa Cruz de la Sierra

When to book flights from Madrid to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Madrid to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Santa Cruz de la Sierra

  • What is the cheapest flight from Madrid to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from Madrid to Santa Cruz de la Sierra was $372 for a one-way ticket and $733 for a round-trip.

  • Do I need a passport to fly between Madrid and Santa Cruz de la Sierra?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Madrid and on arrival in Santa Cruz de la Sierra.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Santa Cruz de la Sierra?

    Iberia, Vueling, and Qatar Airways offer inflight Wi-Fi service on the Madrid to Santa Cruz de la Sierra flight route.

  • Which aircraft models fly most regularly from Madrid to Santa Cruz de la Sierra?

    The Airbus A330-200 is the aircraft model that flies most regularly on the Madrid to Santa Cruz de la Sierra flight route.

  • Which airline alliances offer flights from Madrid to Santa Cruz de la Sierra?

    Star Alliance, and SkyTeam are the airline alliances operating flights between Madrid and Santa Cruz de la Sierra, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Madrid to Santa Cruz de la Sierra?

    You can catch a nonstop flight from Madrid to Santa Cruz de la Sierra on on Monday, Wednesday, Friday, Saturday, and Sunday.

  • Which is the best airline for flights from Madrid to Santa Cruz de la Sierra, Air Europa or Avianca?

    The two airlines most popular with KAYAK users for flights from Madrid to Santa Cruz de la Sierra are Air Europa and Avianca. With an average price for the route of $1,022 and an overall rating of 6.9, Air Europa is the most popular choice. Avianca is also a great choice for the route, with an average price of $810 and an overall rating of 6.5.

  • How does KAYAK find such low prices on flights from Madrid to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Madrid with another airline. Booking your flights between Madrid and VVI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Madrid to Santa Cruz de la Sierra

  • Looking for a cheap flight? 25% of our users found flights on this route for $523 or less one-way.

Prefer to fly direct from Madrid to Santa Cruz de la Sierra?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl.
Find which airlines fly direct from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl

Monday

Air Europa

Air Europa

Wednesday

Air Europa, BoA

Air Europa, BoA

Friday

BoA

BoA

Saturday

Air Europa

Air Europa

Sunday

BoA

BoA

See more direct flights

Direct returns

Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas

Monday

BoA

BoA

Tuesday

Air Europa, BoA

Air Europa, BoA

Thursday

Air Europa, BoA

Air Europa, BoA

Saturday

Air Europa, BoA

Air Europa, BoA

See more direct flights

Reviews of the top airlines flying from Madrid to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
6.9
Air EuropaOverall score based on 590 reviews
6.5Entertainment
7.0Boarding
6.8Comfort
7.4Crew
6.2Food
Airline reviews

My long-haul flight experience with this airline was not very pleasant. Earphones were paid, and no eye mask or other amenities were provided. The meals were served in cardboard boxes with plastic cutlery. The restroom was unclean and ran out of toilet paper. However, the boarding process was smooth and well organized.

4.0 OkayAnonymous, Feb 2026
MAD - MIA
Read more Air Europa reviews

My long-haul flight experience with this airline was not very pleasant. Earphones were paid, and no eye mask or other amenities were provided. The meals were served in cardboard boxes with plastic cutlery. The restroom was unclean and ran out of toilet paper. However, the boarding process was smooth and well organized.

We experienced a delay of almost two hours before takeoff. For a flight of more than 10 hours, sitting on the runway for two hours is quite exhausting. The airline did nothing to attend to the passengers during that time. We were not given any courtesy drinks or snacks—only the bare minimum during the flight. The crew seemed very apologetic, but apparently they have restrictions imposed by the airline, because despite their friendliness, they provided strictly what was necessary and, of course, everything else was for sale. However, after a two-hour delay, one would expect at least complimentary beverages. In addition to this, the space between the rows of seats is inhumanely narrow. Air Europa should review this for such long flights and be a bit more considerate and humane with its customers.

I flew in business a couple of months ago, it was great, tried again in economy, it is the cramped seat I have ever been into, for an overseas flight across the atlantic it is inhumane to put passengers in such cramped space. Other than that, everything ok. Took a second flight from Madrid to London, also economy and it was roomy and perfect.

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

There was no water in one of the sinks in the executive area, which is unacceptable as we could not wash our hands after using the restroom

Like I said the experience was mediocre. Nothing special about this airline.

This flight was delayed by more than an hour. The seats are uncomfortable ans do not recline properly. I prepurchased a wifi pass, but wifi was not working on this flight at all. The food was bland.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

I was not allowed to cancel the flight, customer service is atrocious

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

I had bad experiences before now was excellent I am glad they have business class again

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

No free snacks nor drinks on very short 30min flight. Entertainment system is over wifi to your own phone or tablet, which is good but often a show or movie just stops and refuses to continue

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

Everything you need to know for your flight from Madrid to Santa Cruz de la Sierra

Information on your arrival and departure airports