MAD - VVI

$409 Find Cheap Flights from Madrid to Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Santa Cruz de la Sierra departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Madrid to Santa Cruz de la Sierra (MAD-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Madrid to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Madrid to Santa Cruz de la Sierra

Wed, Nov 5 - Tue, Nov 25
Avianca Logo
10:55 am - 2:00 amMAD-VVI
20h 05m1 stop
Avianca Logo
3:05 am - 10:35 pmVVI-MAD
14h 30m1 stop
$831Avianca
Find Deal
Mon, Sep 1 - Tue, Oct 28
Avianca Logo
9:40 am - 1:50 amMAD-VVI
22h 10m1 stop
Avianca Logo
3:05 am - 6:30 amVVI-MAD
22h 25m1 stop
$832Avianca
Find Deal
Sat, Nov 22 - Mon, Feb 9
Avianca Logo
8:30 am - 2:00 amMAD-VVI
22h 30m1 stop
Avianca Logo
3:05 am - 10:35 pmVVI-MAD
14h 30m1 stop
$835Avianca
Find Deal
Sun, Aug 31 - Tue, Oct 28
Avianca Logo
1:30 am - 1:50 amMAD-VVI
30h 20m1 stop
Avianca Logo
3:05 am - 10:35 pmVVI-MAD
14h 30m1 stop
$872Avianca
Find Deal
Fri, Nov 14 - Tue, Jan 20
 Logo
9:00 pm - 2:30 amMAD-VVI
10h 30mnonstop
 Logo
3:05 am - 1:25 pmVVI-MAD
29h 20m1 stop
Fri, Nov 14 - Tue, Jan 20
 Logo
9:00 pm - 2:30 amMAD-VVI
10h 30mnonstop
 Logo
3:05 am - 10:35 pmVVI-MAD
14h 30m1 stop
Thu, Oct 30 - Tue, Nov 18
LATAM Airlines Logo
12:10 am - 4:35 amMAD-VVI
33h 25m1 stop
LATAM Airlines Logo
5:20 am - 4:25 pmVVI-MAD
30h 05m1 stop
$1,091LATAM Airlines
Find Deal
Tue, Nov 4 - Wed, Nov 26
LATAM Airlines Logo
12:10 am - 4:35 amMAD-VVI
33h 25m1 stop
LATAM Airlines Logo
5:25 am - 4:25 pmVVI-MAD
30h 00m1 stop
$1,092LATAM Airlines
Find Deal
Fri, Sep 26 - Sat, Oct 11
United Airlines Logo
11:15 am - 10:25 pmMAD-VVI
41h 10m2 stops
United Airlines Logo
1:09 am - 8:05 amVVI-MAD
48h 56m2 stops
$1,193United Airlines
Find Deal
Fri, Sep 5 - Sat, Sep 27
United Airlines Logo
11:15 am - 10:25 pmMAD-VVI
41h 10m2 stops
United Airlines Logo
1:09 am - 8:05 amVVI-MAD
24h 56m2 stops
$1,195United Airlines
Find Deal
Expert advice

Expert advice for your flight from Madrid to Santa Cruz de la Sierra

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Air Europa

Air Europa offers speedy Wi-Fi with packages for all needs during your flight.


Air Europa provides special meals including diabetic, gluten-free, and vegan options on transatlantic flights.

Iberia

Iberia’s Business class offers roomy seating with all-aisle access and comfortable bedding.


Enjoy Spanish cuisine with two meals and a variety of beverages on long-haul flights.

Read more about Iberiaby Marisa Garcia
Our travel experts
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff

Laura Ratliff

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Read more
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more
Useful Info

KAYAK's insights & trends for Madrid to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Madrid to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Madrid to Santa Cruz de la Sierra?

The average price of all round-trip flights from Madrid to Santa Cruz de la Sierra clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Santa Cruz de la Sierra on a Saturday, as we generally find the cheapest rates on that day for this route. On the other hand, Friday is the most expensive day to fly from Madrid to Santa Cruz de la Sierra. For your return ticket, we recommend flying on a Tuesday and avoiding Saturdays for the best deals.

What is the cheapest month to fly from Madrid to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madrid to Santa Cruz de la Sierra is May, where tickets cost $785 (return) on average. On the other hand, the most expensive months are August and December, where the average cost of round-trip tickets is $1,426 and $1,393 respectively.

Can I save money by flying with a layover from Madrid to Santa Cruz de la Sierra?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $1,822 on average.

How far in advance should I book a flight from Madrid to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Madrid to Santa Cruz de la Sierra, you should book around 3 weeks before departure. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Good to know

Low seasonOctober
High seasonDecember
Cheapest flight$409
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly with an average 35% increase in price.
Flight from Madrid to Santa Cruz de la Sierra

When to book flights from Madrid to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Madrid to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Santa Cruz de la Sierra

  • What is the cheapest flight from Madrid to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from Madrid to Santa Cruz de la Sierra was $409 for a one-way ticket and $831 for a round-trip.

  • Do I need a passport to fly between Madrid and Santa Cruz de la Sierra?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Madrid and on arrival in Santa Cruz de la Sierra.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Santa Cruz de la Sierra?

    Iberia, Lufthansa, Qatar Airways, and Vueling offer inflight Wi-Fi service on the Madrid to Santa Cruz de la Sierra flight route.

  • Which aircraft models fly most regularly from Madrid to Santa Cruz de la Sierra?

    The Boeing 787 Dreamliner is the aircraft model that flies most regularly on the Madrid to Santa Cruz de la Sierra flight route.

  • Which airline alliances offer flights from Madrid to Santa Cruz de la Sierra?

    oneworld, and SkyTeam are the airline alliances operating flights between Madrid and Santa Cruz de la Sierra, with SkyTeam being the most commonly used for this route.

  • On which days can I fly direct from Madrid to Santa Cruz de la Sierra?

    You can catch a nonstop flight from Madrid to Santa Cruz de la Sierra on on Monday, Wednesday, Friday, and Sunday.

  • Which is the best airline for flights from Madrid to Santa Cruz de la Sierra, LATAM Airlines or Iberia?

    The two airlines most popular with KAYAK users for flights from Madrid to Santa Cruz de la Sierra are LATAM Airlines and Iberia. With an average price for the route of $1,169 and an overall rating of 7.5, LATAM Airlines is the most popular choice. Iberia is also a great choice for the route, with an average price of $1,117 and an overall rating of 7.0.

  • How does KAYAK find such low prices on flights from Madrid to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Madrid with another airline. Booking your flights between Madrid and VVI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Madrid to Santa Cruz de la Sierra

  • Looking for a cheap flight? 25% of our users found flights on this route for $493 or less one-way and $1,022 or less round-trip.

Prefer to fly direct from Madrid to Santa Cruz de la Sierra?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl.
Find which airlines fly direct from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl

Monday

Air Europa

Air Europa

Wednesday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Friday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Sunday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

See more direct flights

Direct returns

Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas

Monday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Tuesday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Thursday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

Saturday

Air Europa, BoA, Iberia

Air Europa, BoA, +1 more

See more direct flights

Reviews of the top 5 airlines serving from Madrid to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1787 reviews
7.6Boarding
8.1Crew
7.0Entertainment
7.4Comfort
6.7Food
Airline reviews

I travel often with LATAM, it never disappoints me. The service is great, nice crew, latest and some classic movies. I got 3 small meals, cannot complaint. I’ll definitely travel again with them.

10.0 ExcellentRita, Apr 2025LIM - JFK
Read more LATAM Airlines reviews

I travel often with LATAM, it never disappoints me. The service is great, nice crew, latest and some classic movies. I got 3 small meals, cannot complaint. I’ll definitely travel again with them.

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Not sure why there are so many security checks at this airport. Consistently annoying showing passport over and over, checking carryons at gate all the while trying to make tight connection. Basically it was uncomfortable crowded cabin with meidiocre service

Change of gate in Santiago devolved into half plus hour delay and a really tight connection in Lima

Although the flight is goof and the crew is good, the way the airline charges you for every service is ridiculous.

Plane never left the ground. Mech issues - entire trip was rerouted through united.

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

Everything was good except the check in. Could not do it online neither on the machines in the airport. Needed special assistance from the airline desk clerk

Staff encountered friendly and helpful. Flight delayed 1 hour due to mechanical issue, but made it through Atlanta immkgration and security in plenty of time,

Food was terrible, tasteless. I ordered ovo lacto special menu in business class and got vegan tasteless food instead. Really disappointing.

Awful. The flight wasn't actually operated by Iberia, but by American Airlines. I was unable to get my boarding pass and as a result missed my connecting flight.

Very good service from San Jose to Madrid . Ryanair service from Madrid to Brussels 😕

I wish they could put the pre-tsa check on the tickets or global entry.

Couldn’t keep my luggage and had no choice. Ground staff didn’t even bother to explain why.

We upgraded to Business class paying approx. $1,300. Despite the upgrade, we were still required to pay an additional €70 for a checked bag. Furthermore, we were informed that another €70 would have been charged for our carry-on bag, as it was 3kg over the limit. To avoid this, we had to move clothing from the carry-on into the checked bag, which was both inconvenient and frustrating. Given the significant amount paid for the Business Class upgrade, we found this treatment to be quite appalling and disappointing. We expected a higher level of service and consideration for our luggage, and this experience did not meet those expectations.

Great flight, short and good attention. Didn't took any food so can't say thing about it

Excellent with no delays and according to the time schedule.

Its a bus taking you on and off the plane so if you have big luggage … more muscles needed

Flight LIN MAD. Checkin was fine (but I must admit that being a Platinum member I skip the lines). Security was fine (they have the new machines where you need not take laptops or liquids out). Longe was OK (BA). Boarding was a mess, the boarding gate personnel were rude and some should simply not be in a customer facing position. Flight in itself was fine, usual Iberia European coach. We were on time and actually time to deliver luggage was better than normal for Barajas

Everything should improve! Service like a low cost but prices like a premium airline. Crew in general with bad manners arguing for everything. You pay for priority access but then they use buses, so your loose your advantage to put your carry on first. That was the purpose for paying for priority. Bording is a nightmare, people accessing the plane for bothering doors, front and rear, no matter which line do you have.

Issues with plane led to multiple gate changes and chaos. Very little communication from the ground crew led to cranky passengers.

I flew business class, at breakfast I asked for a small bottle of olive oil instead of butter and the flight attendant responded with a negative gesture.

They didn't even give us water, everything was sold

They should at least offer water like other airlines, which seems like a humanitarian gesture to me

They gave me an upgrade but charged me for my bag. I felt abused because this had never happened to me before with an upgrade with another airline.

Well. It is a no frills airline. Annoying is that even for the long-haul everything has to be paid for separately. Once you add up the extras the flight is getting to expensive. Then one might as well fly with a legacy carrier which provides far better comfort. Changing flight at MAD airport is a nightmare. The worst airport in the world. Poor signposting, poor passport control, poor security check and long queues. I had 2h transfer time and spend in queues almost 1.5h

All flights with Air Europa you arrive late to the connections of other flights, I missed my train, I had to pay for my train again, the crew are antisocial, you are paying for a service, it is not free, thanks to the travelers they are there, it is the last time I fly with them,

Terrible experience - we won’t be flying with Air Europa again

The crew was not kind , just doing their job but very cold people

The crew was great, professional and polite. Good meal too. The flight was full and we departed on time out of Miami. I did feel cramped in my seat for the long overnight flight, which made it hard to sleep

This airline and their crew is so professional and kind, the trip was short and easy.

It was a very smooth process. Everything about the Airline like a well oiled machine.

Muy horrible experiencia, cambiaron dos veces la hora del vuelo resultando en una espera exagerada. No dan información oportuna. Abordadnos el avión retrasado el vuelo y esperamos dentro del avión por 35’ más mientras subían como 6 carros de cajas al avión. Muy mala logística y servicio.

6 horas de retraso en el vuelo sin ninguna explicación por parte de la aerolínea.

Always late, the service is a sandwich, no comfort at all…

They had a problem with their air conditioning system and we almost had heat strokes because they blasted HEATED AIR for almost 40 minutes and there was literally no air. This is the worst airline in Bolivia. Can't believe we have no other options sometimes.

BOA is truly the worst airline in Bolivia. It's a shame we sometimes need to use it cause we have no more options.

BOA airplanes are so old and dirty, the bathroom was so nasty, it smelled so bad and had tape all over the cabinets. My chair wouldn't recline, we had no entertainment, the flight was super cold. The only positive thing about this flight is that I feel it's so old that they even serve food, like in the past! I travel a lot and nowadays the companies only serve some snacks or sometimes offer something to eat if you pay. Not the case with this flight. Never again flying with BOA. They are definetly the worst.

This airline is always THE WORST. They seem to have flights moving to other times (late) 90% of the time. The airplanes are old, and the landing (i really don't know why) is 90% of the time shaky. I actually never buy tickets from BOA, I prefer other airlines by far.

Seats are very tight even in Plus, no complimentary snacks or beverage

The chicken that was served in business class was cold!

Flight to Bogotá delayed by 3 h Missed connection from Bogotá to Guayaquil. Avianca unable to bring us to Baltra on time Overall delay 36h. We missed boat departure from galagos. Overall 10 day trip needed to be cancelled. Avianca was completely un-professional.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

The seats were very uncomfortable. I would have upgrade or got different flight if I knew. I usually sleep in the plane but I couldn’t sleep at all. Very uncomfortable. Also no food or drink everything was to purchase, and that’s u usual for international flight.

Flew with our two children. Paid $380 to check two bags (one was overweight). They then left the bags behind on Sunday, December 21st, with all our family’s clothes and family Christmas presents. When we arrived at our destination they told us the bags had not arrived, and they thought (but didn’t know) they were still in Boston, but that there’d be a flight the next day and the bags would arrive the next day. The next day we found out there was no flight, now we’re hoping we get our bags before we fly back out. Meanwhile, trying to get any engagement or accurate information is a waste of time. The folks at the call center are just gatekeepers, who can’t connect with any departments that actually do things to solve a problem. Getting information is made deliberately difficult. My biggest regret is that I’ve had a number of awful experiences with Avianca traveling between the US and Colombia, and still let myself get suckered into buying these tickets because the schedule was great. Never again.

So so, you feel like you have to pay for everything each time

Overpriced checked bag price of $120 and they charge you for carryon if the size is not minimal of $120.

Everything you need to know for your flight from Madrid to Santa Cruz de la Sierra

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