MAD - VVI

$470 Find Cheap Flights from Madrid to Santa Cruz de la Sierra

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Madrid to Santa Cruz de la Sierra departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Santa Cruz de la Sierra

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Madrid to Santa Cruz de la Sierra, as well as popular online travel agencies
Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

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Filter your dealsChoose cabin class, free Wi-Fi and more.

Everything you should know

Cheapest round-trip
$861
Overall average: $890
Avianca
dom. 5/31dom. 6/14
MAD - VVI • 1 stop
Cheapest non-stop
$958
Typical prices: $835-$1,003
Air Europa
vie. 5/15sáb. 5/30
MAD - VVI • Non-stop
Our travelers' advice
AI-powered summary based on content written by travel experts. AI can make mistakes.
Air Europa offers speedy Wi-Fi for all needs.
Iberia serves Spanish cuisine with two meals onboard.
Expert advice
Expert advice
Expert advice
Expert advice
When to book
3 weeks
in advance
Our data shows that travelers who book at least 3 weeks in advance save around 16% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 18% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
Nonstop flights
5 days a week
There are direct flights from Madrid to Santa Cruz de la Sierra 5 days a week: Mon, Wed, Fri, Sat, Sun.
Direct flights
Direct flights
Direct flights
Direct flights
Start a new search
KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Santa Cruz de la Sierra!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Madrid to Santa Cruz de la Sierra (MAD-VVI)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Madrid to Santa Cruz de la Sierra that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Madrid to Santa Cruz de la Sierra

dom., may. 31 - dom., jun. 14
Avianca Logo
1:30 am - 1:50 am
MAD
-
VVI
30h 20m
1 stop
Avianca Logo
2:55 am - 11:30 pm
VVI
-
MAD
14h 35m
1 stop
$861Avianca
lun., abr. 20 - vie., may. 1
Avianca Logo
1:30 am - 1:50 am
MAD
-
VVI
30h 20m
1 stop
Avianca Logo
2:55 am - 2:05 pm
VVI
-
MAD
29h 10m
1 stop
$864Avianca
sáb., mar. 21 - mié., abr. 15
Avianca Logo
6:40 am - 2:35 am
MAD
-
VVI
24h 55m
1 stop
Avianca Logo
2:55 am - 7:40 am
VVI
-
MAD
22h 45m
1 stop
$865Avianca
dom., may. 31 - lun., jun. 15
Avianca Logo
1:30 am - 1:50 am
MAD
-
VVI
30h 20m
1 stop
Avianca Logo
2:55 am - 6:05 pm
VVI
-
MAD
33h 10m
2 stops
$872Avianca
vie., may. 15 - vie., may. 29
Avianca Logo
9:40 am - 1:50 am
MAD
-
VVI
22h 10m
1 stop
Avianca Logo
2:55 am - 7:40 am
VVI
-
MAD
22h 45m
1 stop
$873Avianca
dom., may. 31 - vie., jun. 19
Avianca Logo
1:30 am - 1:50 am
MAD
-
VVI
30h 20m
1 stop
Avianca Logo
2:55 am - 6:05 pm
VVI
-
MAD
33h 10m
2 stops
$875Avianca
dom., may. 31 - vie., jun. 19
Avianca Logo
1:30 am - 1:50 am
MAD
-
VVI
30h 20m
1 stop
Avianca Logo
2:55 am - 11:30 pm
VVI
-
MAD
14h 35m
1 stop
$876Avianca
lun., jun. 1 - dom., jun. 14
Avianca Logo
1:30 am - 1:50 am
MAD
-
VVI
30h 20m
1 stop
Avianca Logo
2:55 am - 2:05 pm
VVI
-
MAD
29h 10m
1 stop
$878Avianca
mar., jun. 2 - mié., jun. 17
Avianca Logo
9:40 am - 1:50 am
MAD
-
VVI
22h 10m
1 stop
Avianca Logo
2:55 am - 11:30 pm
VVI
-
MAD
14h 35m
1 stop
$879Avianca
mar., feb. 24 - sáb., mar. 14
Avianca Logo
10:50 am - 2:35 am
MAD
-
VVI
20h 45m
1 stop
Avianca Logo
3:40 am - 1:25 pm
VVI
-
MAD
28h 45m
1 stop
$881Avianca
Booking Insights

KAYAK's insights & trends for Madrid to Santa Cruz de la Sierra flights

Get data-powered insights and trends into flights from Madrid to Santa Cruz de la Sierra to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Madrid to Santa Cruz de la Sierra?

The average price of all round-trip flights from Madrid to Santa Cruz de la Sierra clicked on KAYAK for each day over the last 12 months.

If your flying dates are flexible, you should consider flying to Santa Cruz de la Sierra on a Thursday, as we generally find the cheapest rates on that day for this route. On the other hand, Monday is the most expensive day to fly from Madrid to Santa Cruz de la Sierra. For your return ticket, we recommend flying on a Thursday and avoiding Saturdays for the best deals.

What is the cheapest month to fly from Madrid to Santa Cruz de la Sierra?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Madrid to Santa Cruz de la Sierra is March, where tickets cost $884 (return) on average. On the other hand, the most expensive months are August and December, where the average cost of round-trip tickets is $1,398 and $1,368 respectively.

Can I save money by flying with a layover from Madrid to Santa Cruz de la Sierra?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $958 on average.

How far in advance should I book a flight from Madrid to Santa Cruz de la Sierra?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Madrid to Santa Cruz de la Sierra, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Madrid to Santa Cruz de la Sierra, you should book around 3 weeks before departure, which saves you about 16% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 14 weeks before departure.

Expert advice

Expert advice for your flight from Madrid to Santa Cruz de la Sierra

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
Iberia

Iberia’s Business class offers roomy seating with all-aisle access and comfortable bedding.


Enjoy Spanish cuisine with two meals and a variety of beverages on long-haul flights.

Air Europa

Air Europa offers speedy Wi-Fi with packages for all needs during your flight.


Air Europa provides special meals including diabetic, gluten-free, and vegan options on transatlantic flights.

Our travel experts
Marisa Garcia

Marisa Garcia

Expert on Iberia

Marisa Garcia

Marisa Garcia

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Read more
Laura Ratliff

Laura Ratliff

Expert on Air Europa

Laura Ratliff

Laura Ratliff

Laura Ratliff is a New York-based writer and editor. She lives in downtown Brooklyn with her husband and their beloved dogs. Originally from Texas, she now considers New York City her home. She typically spends more than 200,000 miles on a plane each year and stays in plenty of hotels.

Read more

Good to know

Low seasonMay
Cheapest flight$470
Best time to beat the crowds with an average 18% drop in price.
Most popular time to fly with an average 27% increase in price.
Flight from Madrid to Santa Cruz de la Sierra

When to book flights from Madrid to Santa Cruz de la Sierra

Are your dates flexible? Find out the best times to travel from Madrid to Santa Cruz de la Sierra based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Madrid to Santa Cruz de la Sierra

  • What is the cheapest flight from Madrid to Santa Cruz de la Sierra?

    In the last 3 days, the lowest price for a flight from Madrid to Santa Cruz de la Sierra was $470 for a one-way ticket and $861 for a round-trip.

  • Do I need a passport to fly between Madrid and Santa Cruz de la Sierra?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Madrid and on arrival in Santa Cruz de la Sierra.

  • Which airlines offer Wi-Fi service onboard planes from Madrid to Santa Cruz de la Sierra?

    Iberia, Lufthansa, Vueling, and Qatar Airways offer inflight Wi-Fi service on the Madrid to Santa Cruz de la Sierra flight route.

  • Which aircraft models fly most regularly from Madrid to Santa Cruz de la Sierra?

    The Airbus A330-200 is the aircraft model that flies most regularly on the Madrid to Santa Cruz de la Sierra flight route.

  • Which airline alliances offer flights from Madrid to Santa Cruz de la Sierra?

    Star Alliance, and SkyTeam are the airline alliances operating flights between Madrid and Santa Cruz de la Sierra, with Star Alliance being the most commonly used for this route.

  • On which days can I fly direct from Madrid to Santa Cruz de la Sierra?

    You can catch a nonstop flight from Madrid to Santa Cruz de la Sierra on on Monday, Wednesday, Friday, Saturday, and Sunday.

  • Which is the best airline for flights from Madrid to Santa Cruz de la Sierra, LATAM Airlines or Air Europa?

    The two airlines most popular with KAYAK users for flights from Madrid to Santa Cruz de la Sierra are LATAM Airlines and Air Europa. With an average price for the route of $1,169 and an overall rating of 7.5, LATAM Airlines is the most popular choice. Air Europa is also a great choice for the route, with an average price of $1,019 and an overall rating of 6.9.

  • How does KAYAK find such low prices on flights from Madrid to Santa Cruz de la Sierra?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Madrid to Santa Cruz de la Sierra.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Madrid to Santa Cruz de la Sierra?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santa Cruz de la Sierra from Madrid is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Madrid to Santa Cruz de la Sierra?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santa Cruz de la Sierra with an airline and back to Madrid with another airline. Booking your flights between Madrid and VVI can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Madrid to Santa Cruz de la Sierra?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santa Cruz de la Sierra from Madrid up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Madrid to Santa Cruz de la Sierra

  • Looking for a cheap flight? 25% of our users found flights on this route for $566 or less one-way.

Prefer to fly direct from Madrid to Santa Cruz de la Sierra?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl.
Find which airlines fly direct from Madrid Barajas Airport to Santa Cruz de la Sierra Viru Viru Intl Airport, which days they fly and book direct flights.

Direct departures

Madrid Barajas to Santa Cruz de la Sierra Viru Viru Intl

Monday

Air Europa

Air Europa

Wednesday

Air Europa, BoA

Air Europa, BoA

Friday

BoA

BoA

Saturday

Air Europa

Air Europa

Sunday

BoA

BoA

See more direct flights

Direct returns

Santa Cruz de la Sierra Viru Viru Intl to Madrid Barajas

Monday

BoA

BoA

Tuesday

Air Europa, BoA

Air Europa, BoA

Thursday

Air Europa, BoA

Air Europa, BoA

Saturday

Air Europa, BoA

Air Europa, BoA

See more direct flights

Reviews of the top 4 airlines serving from Madrid to Santa Cruz de la Sierra

 
See real verified KAYAK customer reviews for airlines flying from Madrid to Santa Cruz de la Sierra. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Madrid to Santa Cruz de la Sierra? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1910 reviews
7.6Boarding
8.0Crew
6.7Food
7.0Entertainment
7.3Comfort
Airline reviews

Comfort in exit seat was excellent. FLight crew and flight were excellent. However exit seat tray table was broken so could not use it. Entertainment monitor did not work at all despite attempts to reset it.

8.0 ExcellentAnonymous, Jan 2026
BOG - ATL
Read more LATAM Airlines reviews

Comfort in exit seat was excellent. FLight crew and flight were excellent. However exit seat tray table was broken so could not use it. Entertainment monitor did not work at all despite attempts to reset it.

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Good flight, boarding ok and crew very nice. Flight was not full so I was able to be very comfortable. Blanket and pillow provided with was good as it was very cold during the flight . Food was very good(small snack sandwich and an excellent piece of orange cake). Overall good flight, no complaints.

Wish the seats were a little more comfortable.. it was a 6 hrs nonstop trip. But the crew was courteous and w a smile

I like this airline a lot no problems at all, except being forced to check a carry-on bag ., Overall very good airline

Poor, the airline was not able to help me move flights.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

The way the Pilot made all announcements, specially the way he congratulated the entire crew as the best team ever, making a comment that due to them they were able to shorter the delay to the destination. Amazing flight .

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

No WiFi on the plane. Crew was insensitive to my medical supplies and medicine in my carry on. If the crew was monitoring passengers putting 2 bags in overhead bins there would be room. We sat for 2 hours extra. Iberojet is horrible never again.

There was no water in one of the sinks in the executive area, which is unacceptable as we could not wash our hands after using the restroom

Like I said the experience was mediocre. Nothing special about this airline.

This flight was delayed by more than an hour. The seats are uncomfortable ans do not recline properly. I prepurchased a wifi pass, but wifi was not working on this flight at all. The food was bland.

Food situation was bad. Also movie choices when compared to other airlines was terrible. Seats very narrow. My tv didn’t work.

I was not allowed to cancel the flight, customer service is atrocious

Great staff, just very far from the main terminal, had to run to connect my flight. I had 90 minutes to spare. But my flight from Chicago was delayed also.

My luggage is lost and nowhere to be found, no response from airline

Boarding was a shitshow. Had to bus to the gate. No separate bus and boarding process for Business Class.

The plane was very old, no power outlets. We also had to wait a long time to board. They kept moving us to different lines before we actually could step foot on the plane. We ended up being delayed an hour but we were never told or informed for any reason. After the meal I asked for a coffee which the flight attendant forgot and I had to ask again. Overall not the worst but not the best experience.

Unfortunately had horrible experience Originally booked business class from La Paz to Miami Flight was delayed for 2 hours with no clear explanation

Our flight was canceled and we were put on a different flight, but we were never notified of the change until we checked in. BOA provides no beverage service during the flight and there is no in-flight entertainment. Airline staff tried to tell us that we were not allowed one personal item and one carry-on bag per person, but instead that we were only allowed one item aboard per person, which contradicts their written luggage policy. Airline staff also claimed that a car seat counted against our carry-on allowance, even though our child had his own ticket and is required to use a car seat on board per airline policy.

The crew was great, professional and polite. Good meal too. The flight was full and we departed on time out of Miami. I did feel cramped in my seat for the long overnight flight, which made it hard to sleep

This airline and their crew is so professional and kind, the trip was short and easy.

It was a very smooth process. Everything about the Airline like a well oiled machine.

Muy horrible experiencia, cambiaron dos veces la hora del vuelo resultando en una espera exagerada. No dan información oportuna. Abordadnos el avión retrasado el vuelo y esperamos dentro del avión por 35’ más mientras subían como 6 carros de cajas al avión. Muy mala logística y servicio.

6 horas de retraso en el vuelo sin ninguna explicación por parte de la aerolínea.

Always late, the service is a sandwich, no comfort at all…

They had a problem with their air conditioning system and we almost had heat strokes because they blasted HEATED AIR for almost 40 minutes and there was literally no air. This is the worst airline in Bolivia. Can't believe we have no other options sometimes.

BOA is truly the worst airline in Bolivia. It's a shame we sometimes need to use it cause we have no more options.

Boarding was late due to the company’s that cleaned the aircraft (very poorly done) and the catering company. The entertainment system was not working for this six hour flight, uncomfortable seats in business (barely any cushion or recline). The airline staff is very good but the planes are horrible and not well maintained.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

I like the crew they're very friendly. I don't like. on five hour flight they not offered snacks. Any drink. Not even coffee

Not even water is offered on the flight. You cannot lean back on the seats and the seats are so narrow you can’t avoid rubbing elbows with the person next to you.

This low cost airline looks and fells more like a local bus. In a 6 hour flight not being able to recline a seat is torture. The only thing available with no charge is a glass of water provided by, mostly, rude staff. Our luggage didn’t arrive

Horrible experience. Flight cancelled. Arrived at destination 12 hs later. No one gave us an answer or any information. Very very poor service. We won’t ever travel again with Avianca

Usb plugs for charging your phone does not work in every flight. uncomfortable chairs even in higher categories.

Luggage lost and nowhere to be found, no response from either airline regarding my bag

Not what it used to be. The sale of food makes them look greedy!

Everything you need to know for your flight from Madrid to Santa Cruz de la Sierra

Information on your arrival and departure airports