SNA - BRU

$393 Find Cheap Flights from John Wayne (Santa Ana) to Brussels - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Brussels departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from John Wayne (Santa Ana) to Brussels, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$868
Air Canada, SWISS
Mon 8/10Mon 8/24
SNA - BRU • 2 stops
Cheapest one-way
$393
Brussels Airlines
Wed 11/11
SNA - BRU • 1 stop
Top airlines
Cheapest • from $827 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and Brussels. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $1,327 (round-trip)
Shortest trip • 13h 20m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Brussels!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Ana to Brussels (SNA-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Brussels that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Brussels

Mon, Aug 10 - Mon, Aug 24
Multiple Airlines Logo
1:15 pm - 7:10 am
SNA
-
BRU
32h 55m
2 stops
Multiple Airlines Logo
7:40 pm - 8:51 pm
BRU
-
SNA
34h 11m
2 stops
$868Multiple Airlines
Wed, Aug 19 - Sun, Aug 30
United Airlines Logo
1:08 pm - 8:00 pm
SNA
-
BRU
21h 52m
2 stops
United Airlines Logo
12:00 pm - 8:34 pm
BRU
-
SNA
17h 34m
1 stop
$917United Airlines
Wed, Aug 19 - Sun, Aug 30
Lufthansa Logo
4:11 pm - 7:55 pm
SNA
-
BRU
18h 44m
2 stops
Lufthansa Logo
6:20 am - 6:47 pm
BRU
-
SNA
21h 27m
2 stops
$918Lufthansa
Wed, Aug 19 - Sun, Aug 30
United Airlines Logo
11:10 am - 1:15 pm
SNA
-
BRU
17h 05m
2 stops
United Airlines Logo
9:30 am - 9:17 am
BRU
-
SNA
32h 47m
3 stops
$920United Airlines
Mon, Aug 10 - Mon, Aug 24
Multiple Airlines Logo
2:10 pm - 9:00 am
SNA
-
BRU
33h 50m
1 stop
Multiple Airlines Logo
10:45 am - 8:34 pm
BRU
-
SNA
18h 49m
1 stop
$926Multiple Airlines
Thu, Jul 30 - Fri, Aug 14
Air Canada Logo
1:15 pm - 7:10 am
SNA
-
BRU
32h 55m
2 stops
Air Canada Logo
9:30 am - 6:51 pm
BRU
-
SNA
42h 21m
2 stops
$929Air Canada
Thu, Jul 30 - Fri, Aug 14
United Airlines Logo
9:45 am - 8:00 pm
SNA
-
BRU
25h 15m
2 stops
United Airlines Logo
12:00 pm - 8:34 pm
BRU
-
SNA
17h 34m
1 stop
$947United Airlines
Thu, Aug 6 - Sat, Aug 22
Air Canada Logo
1:15 pm - 7:10 am
SNA
-
BRU
32h 55m
2 stops
Air Canada Logo
9:30 am - 10:17 pm
BRU
-
SNA
45h 47m
2 stops
$949Air Canada
Thu, Jul 30 - Fri, Aug 14
United Airlines Logo
4:00 pm - 8:00 pm
SNA
-
BRU
19h 00m
2 stops
United Airlines Logo
9:30 am - 9:07 am
BRU
-
SNA
32h 37m
3 stops
$950United Airlines
Tue, Sep 1 - Tue, Sep 8
Brussels Airlines Logo
10:33 am - 9:00 am
SNA
-
BRU
13h 27m
1 stop
Brussels Airlines Logo
11:10 am - 5:24 pm
BRU
-
SNA
15h 14m
1 stop
$966Brussels Airlines
Booking Insights

KAYAK's insights & trends for Santa Ana to Brussels flights

Get data-powered insights and trends into flights from Santa Ana to Brussels to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from John Wayne (Santa Ana) to Brussels?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from John Wayne (Santa Ana) to Brussels were found on United Airlines ($827) and Lufthansa ($918).

Good to know

Cheapest flight$393
Flight from John Wayne (Santa Ana) to Brussels

When to book flights from Santa Ana to Brussels

Are your dates flexible? Find out the best times to travel from Santa Ana to Brussels based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking John Wayne (Santa Ana) to Brussels flights

  • What is the cheapest flight from John Wayne (Santa Ana) to Brussels Bruxelles-National Airport?

    In the last 5 days, the lowest price for a flight from John Wayne (Santa Ana) to Brussels Bruxelles-National Airport was $393 for a one-way ticket and $816 for a round-trip.

  • Do I need a passport to fly between John Wayne (Santa Ana) and Brussels?

    Yes, you’ll need a passport to travel to Brussels from John Wayne (Santa Ana).

  • Which aircraft models fly most regularly from John Wayne (Santa Ana) to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from John Wayne (Santa Ana) to Brussels?

    Star Alliance is the only airline alliance operating flights between John Wayne (Santa Ana) and Brussels.

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to John Wayne (Santa Ana) with another airline. Booking your flights between John Wayne (Santa Ana) and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santa Ana to Brussels

 
See real verified KAYAK customer reviews for airlines flying from John Wayne (Santa Ana) to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Brussels? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9842 reviews
7.3Comfort
8.1Crew
7.7Boarding
6.6Food
7.1Entertainment
Airline reviews

I was promised by United Airline (operated by ANA) that I will be seated together with my kids as I am the only adult flying with two minors. We did not get seats together in our 11 hours flight from LA to Tokyo. When asked at the gate, ANA representative said United Airline should have informed them that there is a parent flying with two minors. He said they can’t do anything in the system as the flight is full. He ask me to ask passengers next to me and the kids if they are willing to change seats. This is ridiculous! However, I went in the flight and asked other passages but no one willing to change seats. 11 hours and we were seating separately. I was very disappointed with this. It made things super inconvenient for me.

2.0 MediocreAnonymous, Jun 2026
LAX - NRT
Read more United Airlines reviews

I was promised by United Airline (operated by ANA) that I will be seated together with my kids as I am the only adult flying with two minors. We did not get seats together in our 11 hours flight from LA to Tokyo. When asked at the gate, ANA representative said United Airline should have informed them that there is a parent flying with two minors. He said they can’t do anything in the system as the flight is full. He ask me to ask passengers next to me and the kids if they are willing to change seats. This is ridiculous! However, I went in the flight and asked other passages but no one willing to change seats. 11 hours and we were seating separately. I was very disappointed with this. It made things super inconvenient for me.

Service was professional and quick. Premium economy seat was comfortable given the class

It was perfect! United Airlines staff was extremely caring, super friendly and professional

The staff was extremely helpful and friendly at all times! They went above and beyond to get us into an earlier flight in San Diego to make our connection in SFO possible, because our original flight did actually not make it! I did so much appreciate the UA team and how they made this possible. We also didn’t have seats together on the long flight to Singapore, but they found us seats together last moment with no additional cost! Nobody sat next to us, so that we were able to sleep! Thanks to UA for improving their service and Underpricer for booking this trip! Please be careful: 1,5 hrs for transfer in San Francisco might not be enough time in the future

Over 2.5 hour maintenance delay on first morning flight with no acknowledgement, compensation or even gesture of good will. Aircraft had overnighted at airport so issue should have been addressed prior to boarding. Over 3.5 hours before first slow and deliberate beverage service.

United has maintenance issues and can then never recover. No operations ability and simple issues always turn into multiple hours long cascading delays. Worst airline on earth.

I paid for a confirmed upgraded aisle seat and was moved to a center seat in the back of the plane at the last minute.

Horrifying Almost 2 million miles. Bring your own food and drink. One coffee or drink every three hours. Have to order meals on app more than 24 hours ahead Tiny and dirty bathrooms

Flight was delayed but more than 90 minutes. This caused me to miss my available windows for pick-up by a friend. I had to pay $125 for an uber back home from the airport which was an added expense that I had not budgeted for my trip. Staff was friendly.

Seat pitch is horrible especially on the 15 hour flight. Gate crew at SFO was Outstanding. The flight crew was also great.

Everything you need to know for your flight from Santa Ana to Brussels

Information on your arrival and departure airports