SNA - BRU

$645 Find Cheap Flights from John Wayne (Santa Ana) to Brussels

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Brussels departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Brussels, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Santa Ana to Brussels

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Brussels that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Brussels

Mon, Oct 20 - Mon, Nov 3
United Airlines Logo
10:30 am - 9:00 amSNA-BRU
13h 30m1 stop
United Airlines Logo
10:10 am - 6:00 pmBRU-SNA
16h 50m1 stop
$645United Airlines
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Wed, Jun 4 - Tue, Jun 10
Icelandair Logo
7:14 pm - 12:50 pmSNA-BRU
32h 36m2 stops
Icelandair Logo
1:50 pm - 10:30 pmBRU-SNA
17h 40m2 stops
$989Icelandair
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Mon, May 19 - Sat, Jun 28
Air Canada Logo
1:35 pm - 8:05 amSNA-BRU
33h 30m2 stops
Air Canada Logo
10:00 am - 12:29 pmBRU-SNA
35h 29m2 stops
$1,084Air Canada
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Wed, Jun 11 - Tue, Jun 24
 Logo
6:50 am - 7:50 amSNA-BRU
16h 00m2 stops
 Logo
10:00 am - 12:29 pmBRU-SNA
35h 29m2 stops
$1,090
Find Deal
Tue, Jun 10 - Tue, Jun 24
Air Canada Logo
1:25 pm - 9:45 amSNA-BRU
35h 20m2 stops
Air Canada Logo
10:00 am - 10:12 pmBRU-SNA
21h 12m2 stops
$1,092Air Canada
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Wed, Jun 11 - Wed, Jun 25
Delta Logo
6:45 am - 8:40 amSNA-BRU
16h 55m2 stops
Delta Logo
10:45 am - 9:49 pmBRU-SNA
20h 04m2 stops
$1,098Delta
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Thu, Jun 12 - Wed, Jun 25
Delta Logo
6:45 am - 8:40 amSNA-BRU
16h 55m1 stop
Delta Logo
10:45 am - 7:16 pmBRU-SNA
17h 31m1 stop
$1,164Delta
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Tue, Jun 10 - Mon, Jun 23
Lufthansa Logo
11:35 am - 4:15 pmSNA-BRU
19h 40m2 stops
Lufthansa Logo
7:00 am - 10:00 pmBRU-SNA
24h 00m2 stops
$1,210Lufthansa
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Thu, Jun 19 - Thu, Jun 26
 Logo
5:22 pm - 10:00 amSNA-BRU
31h 38m3 stops
 Logo
8:50 pm - 8:55 amBRU-SNA
45h 05m3 stops
$1,292
Find Deal
Wed, Jun 11 - Mon, Jun 23
Lufthansa Logo
5:53 pm - 7:50 pmSNA-BRU
16h 57m2 stops
Lufthansa Logo
7:00 am - 8:47 pmBRU-SNA
22h 47m2 stops
$1,310Lufthansa
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KAYAK's insights & trends for Santa Ana to Brussels flights

Get data-powered insights and trends into flights from Santa Ana to Brussels to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from John Wayne (Santa Ana) to Brussels?

The average price of all round-trip flights from Santa Ana to Brussels Bruxelles-National Airport clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Brussels on a Wednesday and more expensive on a Sunday. On your return trip to John Wayne (Santa Ana), you should consider flying back on a Tuesday, and avoid Thursdays for better deals.

Good to know

Cheapest flight$645
Flight from John Wayne (Santa Ana) to Brussels

When to book flights from Santa Ana to Brussels

Are your dates flexible? Find out the best times to travel from Santa Ana to Brussels based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking John Wayne (Santa Ana) to Brussels flights

  • What is the cheapest flight from Santa Ana to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Santa Ana to Brussels Bruxelles-National Airport was $659 for a one-way ticket and $645 for a round-trip.

  • Do I need a passport to fly between John Wayne (Santa Ana) and Brussels?

    Yes, you’ll need a passport to travel to Brussels from John Wayne (Santa Ana).

  • Which aircraft models fly most regularly from John Wayne (Santa Ana) to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from John Wayne (Santa Ana) to Brussels?

    oneworld, Star Alliance, and SkyTeam are the airline alliances operating flights between John Wayne (Santa Ana) and Brussels, with SkyTeam being the most commonly used for this route.

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to John Wayne (Santa Ana) with another airline. Booking your flights between John Wayne (Santa Ana) and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Top airline flying from Santa Ana to Brussels

 
See real verified KAYAK customer reviews for airlines flying from Santa Ana to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Brussels? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 8708 reviews
6.6Food
8.1Crew
7.3Comfort
7.1Entertainment
7.7Boarding
Airline reviews

Liked fold flat bed. Didn’t like having no window. Didn’t like poor choice of food and being served dinner very late, hours after take off of a 7:40pm flight. Servers not friendly. Food horrible in business class.

2.0 MediocreJane, May 2025SFO - LHR
Read more United Airlines reviews

Liked fold flat bed. Didn’t like having no window. Didn’t like poor choice of food and being served dinner very late, hours after take off of a 7:40pm flight. Servers not friendly. Food horrible in business class.

Everything is good except the dinner and breakfast. The sandwich is very delicious. Toilet is clean, I only use one of them. Flight attendants are very nice. 👍👍

The gate was too far away for the connecting flight

Compared with other carriers business class for an overnight was not worth the extra expense.

Seats were comfortable. It’s was so cold and very uncomfortable. I paid 2000 miles for wifi service that was choppy the whole flight. Would like to be reimbursed for my miles Food was so disappointing. Three cold and terrible meals for $3000 round trip. This needs to be better.

Easy to board. Flight was super crowded though so I didn't sleep well on that cross country red-eye flight. The aisles seem ot have gotten narrower and the seat smaller whn luggage and people are getting bigger so it would be AWESOME to have more space and breathing room in general ;)

Pilot Erika DeLong made us feel safe and at ease in a frankly scary time to be flying. Her warm smile and greeting and excellent command of the aircraft in foggy bumpy weather helped us all to calm our nerves and get us home safely.

Plenty of room for me and the cat in Premium Economy. Seat was comfortable. Boarding was a breeze. The lady at the special check-in desk was great, super helpful and professional.

Smooth flight. As always dinner could have been more generous. Breakfast was great.

AWFUL. I have had the experience of traveling with many airlines across the world, and hands down United Airlines is the worst. Not one flight was on time, and I don’t think I met one crew member or staff member who wasn’t rude.

Everything you need to know for your flight from Santa Ana to Brussels

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