SNA - BRU

$355 Find Cheap Flights from John Wayne (Santa Ana) to Brussels

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Brussels departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Brussels Bruxelles-National Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Brussels, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santa Ana to Brussels, as well as popular online travel agencies
Travelers love KAYAK
41 299 237 searches in the past 7 days on KAYAK

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Everything you should know

Cheapest round-trip
$641
Multiple Airlines
Sun 4/26Sun 5/3
SNA - BRU • 2 stops
Cheapest one-way
$355
Multiple Airlines
Tue 3/31
SNA - BRU • 2 stops
Top airlines
United Airlines
Cheapest • from $647 (round-trip)
United Airlines
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and Brussels. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Amsterdam (AMS)
Cheapest • Avg $1,288 (round-trip)
Amsterdam (AMS)
Shortest trip • 12h 45m (one-way)
Insights
Insights
Insights
Insights
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Brussels!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Santa Ana to Brussels (SNA-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Brussels that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Brussels

Sun, Apr 26 - Sun, May 3
Multiple Airlines Logo
12:25 pm - 8:00 pm
SNA
-
BRU
22h 35m
2 stops
Multiple Airlines Logo
9:55 am - 12:20 pm
BRU
-
SNA
35h 25m
2 stops
$641Multiple Airlines
Sun, Apr 26 - Sun, May 3
United Airlines Logo
12:25 pm - 8:55 am
SNA
-
BRU
35h 30m
2 stops
United Airlines Logo
10:15 am - 10:35 pm
BRU
-
SNA
21h 20m
1 stop
$647United Airlines
Thu, Apr 16 - Thu, Apr 23
Air Canada Logo
12:25 pm - 7:10 am
SNA
-
BRU
33h 45m
2 stops
Air Canada Logo
9:55 am - 11:15 am
BRU
-
SNA
34h 20m
2 stops
$648Air Canada
Sun, Apr 19 - Tue, May 5
British Airways Logo
4:23 pm - 10:05 am
SNA
-
BRU
32h 42m
2 stops
British Airways Logo
10:55 am - 9:13 pm
BRU
-
SNA
19h 18m
2 stops
$654British Airways
Thu, Apr 23 - Wed, Apr 29
United Airlines Logo
12:25 pm - 1:15 pm
SNA
-
BRU
39h 50m
2 stops
United Airlines Logo
10:30 am - 9:45 pm
BRU
-
SNA
20h 15m
2 stops
$655United Airlines
Thu, Apr 23 - Wed, Apr 29
United Airlines Logo
1:21 pm - 1:15 pm
SNA
-
BRU
14h 54m
2 stops
United Airlines Logo
10:15 am - 10:35 pm
BRU
-
SNA
21h 20m
1 stop
$677United Airlines
Wed, Apr 22 - Thu, May 7
British Airways Logo
1:36 pm - 3:05 pm
SNA
-
BRU
16h 29m
2 stops
British Airways Logo
10:50 am - 8:12 pm
BRU
-
SNA
18h 22m
2 stops
$703British Airways
Thu, Apr 23 - Wed, Apr 29
United Airlines Logo
6:45 am - 9:00 am
SNA
-
BRU
17h 15m
1 stop
United Airlines Logo
10:15 am - 10:35 pm
BRU
-
SNA
21h 20m
1 stop
$705United Airlines
Thu, Apr 23 - Wed, Apr 29
Multiple Airlines Logo
12:25 pm - 7:10 am
SNA
-
BRU
33h 45m
2 stops
Multiple Airlines Logo
9:55 am - 10:35 pm
BRU
-
SNA
21h 40m
3 stops
$708Multiple Airlines
Tue, Mar 31 - Thu, Apr 16
British Airways Logo
12:52 pm - 3:15 pm
SNA
-
BRU
17h 23m
2 stops
British Airways Logo
10:50 am - 10:05 pm
BRU
-
SNA
20h 15m
2 stops
$710British Airways
Booking Insights

KAYAK's insights & trends for Santa Ana to Brussels flights

Get data-powered insights and trends into flights from Santa Ana to Brussels to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from John Wayne (Santa Ana) to Brussels?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from John Wayne (Santa Ana) to Brussels were found on United Airlines ($647) and Air Canada ($648).

Find deals

Good to know

Cheapest flight$355
Flight from John Wayne (Santa Ana) to Brussels

When to book flights from Santa Ana to Brussels

Are your dates flexible? Find out the best times to travel from Santa Ana to Brussels based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking John Wayne (Santa Ana) to Brussels flights

  • What is the cheapest flight from Santa Ana to Brussels Bruxelles-National Airport?

    In the last 3 days, the lowest price for a flight from Santa Ana to Brussels Bruxelles-National Airport was $355 for a one-way ticket and $641 for a round-trip.

  • Do I need a passport to fly between John Wayne (Santa Ana) and Brussels?

    Yes, you’ll need a passport to travel to Brussels from John Wayne (Santa Ana).

  • Which aircraft models fly most regularly from John Wayne (Santa Ana) to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from John Wayne (Santa Ana) to Brussels?

    Star Alliance is the only airline alliance operating flights between John Wayne (Santa Ana) and Brussels.

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to John Wayne (Santa Ana) with another airline. Booking your flights between John Wayne (Santa Ana) and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santa Ana to Brussels

 
See real verified KAYAK customer reviews for airlines flying from Santa Ana to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Brussels? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9403 reviews
7.1Entertainment
7.7Boarding
7.3Comfort
6.6Food
8.1Crew
Airline reviews

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

6.0 GoodAnonymous, Mar 2026
SFO - DEN
Read more United Airlines reviews

Seats are uncomfortable. This has been a trend in the industry for decades. Trying to fit more seats on each plane to increase profits at the expense of the passenger.

Staff were good. My seat was in need of repair, but for a short flight was not problematic. Usual basic snack and drink setup that you'll find on any US carrier. Over, a decent, basic flight.

Complimentary light meal would be appreciated. But great flight crew service on all legs

Flight delayed for more than 16 hrs and no effort was spent to provide an alternate

We had turbulence ever 1/2 hr or so and the captains announcements were SOOOO LOUD

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

it was a very short flight so my expectations were low.

Entertainment kept turning itself off. Gave up on watching a movie.

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Everything you need to know for your flight from Santa Ana to Brussels

Information on your arrival and departure airports

John Wayne (Santa Ana) (SNA)
Bruxelles-National (BRU)