SNA - BRU

$420 Find Cheap Flights from John Wayne (Santa Ana) to Brussels - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santa Ana to Brussels departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Everything you should know

Cheapest round-trip
$785
Air Canada
Mon 11/30Sun 12/6
SNA - BRU • 2 stops
Cheapest one-way
$420
Multiple Airlines
Sat 8/15
SNA - BRU • 3 stops
Top airlines
Cheapest • from $796 (round-trip)
Best reviews • 7.4 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Nonstop flights
Not available
There are currently no direct flights between Santa Ana and Brussels. You'll need at least 1 connection.
Insights
Insights
Insights
Insights
Top layover airports
Cheapest • Avg $1,327 (round-trip)
Shortest trip • 13h 20m (one-way)
Insights
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Booking Insights
Flight Deals

Cheap Flights from Santa Ana to Brussels (SNA-BRU)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santa Ana to Brussels that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santa Ana to Brussels

Mon, Nov 30 - Sun, Dec 6
Multiple Airlines Logo
12:35 pm - 8:00 pm
SNA
-
BRU
22h 25m
2 stops
Multiple Airlines Logo
10:00 am - 12:45 pm
BRU
-
SNA
35h 45m
2 stops
$785Multiple Airlines
Mon, Nov 30 - Sun, Dec 6
United Airlines Logo
9:40 am - 1:15 pm
SNA
-
BRU
18h 35m
2 stops
United Airlines Logo
10:10 am - 6:20 pm
BRU
-
SNA
17h 10m
1 stop
$796United Airlines
Mon, Nov 30 - Sun, Dec 6
United Airlines Logo
8:50 am - 1:15 pm
SNA
-
BRU
19h 25m
2 stops
United Airlines Logo
10:00 am - 9:44 am
BRU
-
SNA
32h 44m
3 stops
$799United Airlines
Mon, Nov 30 - Sun, Dec 6
KLM Logo
2:00 pm - 10:55 am
SNA
-
BRU
35h 55m
1 stop
KLM Logo
12:55 pm - 10:29 pm
BRU
-
SNA
18h 34m
1 stop
$806KLM
Sun, Aug 16 - Tue, Aug 25
United Airlines Logo
6:25 pm - 9:00 am
SNA
-
BRU
29h 35m
2 stops
United Airlines Logo
9:30 am - 5:24 pm
BRU
-
SNA
40h 54m
2 stops
$844United Airlines
Sun, Aug 16 - Tue, Aug 25
Multiple Airlines Logo
7:45 am - 7:40 am
SNA
-
BRU
14h 55m
1 stop
Multiple Airlines Logo
9:45 am - 9:56 pm
BRU
-
SNA
21h 11m
1 stop
$860Multiple Airlines
Sun, Aug 16 - Tue, Aug 25
Multiple Airlines Logo
6:25 pm - 7:10 am
SNA
-
BRU
27h 45m
2 stops
Multiple Airlines Logo
9:55 am - 12:23 pm
BRU
-
SNA
35h 28m
2 stops
$861Multiple Airlines
Sun, Aug 16 - Tue, Aug 25
Delta Logo
7:45 am - 7:40 am
SNA
-
BRU
14h 55m
1 stop
Delta Logo
9:45 am - 8:51 am
BRU
-
SNA
32h 06m
2 stops
$864Delta
Wed, Jul 29 - Tue, Aug 4
United Airlines Logo
4:12 pm - 8:00 pm
SNA
-
BRU
18h 48m
2 stops
United Airlines Logo
12:00 pm - 9:07 am
BRU
-
SNA
30h 07m
2 stops
$900United Airlines
Wed, Jul 29 - Tue, Aug 4
KLM Logo
2:09 pm - 2:40 pm
SNA
-
BRU
15h 31m
2 stops
KLM Logo
9:45 am - 9:56 pm
BRU
-
SNA
21h 11m
1 stop
$908KLM
Booking Insights

KAYAK's insights & trends for Santa Ana to Brussels flights

Get data-powered insights and trends into flights from Santa Ana to Brussels to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from John Wayne (Santa Ana) to Brussels?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 5 days.

In the past 5 days, the cheapest round-trip tickets from John Wayne (Santa Ana) to Brussels were found on United Airlines ($796) and KLM ($806).

Good to know

Cheapest flight$420
Flight from John Wayne (Santa Ana) to Brussels

When to book flights from Santa Ana to Brussels

Are your dates flexible? Find out the best times to travel from Santa Ana to Brussels based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking John Wayne (Santa Ana) to Brussels flights

  • What is the cheapest flight from John Wayne (Santa Ana) to Brussels Bruxelles-National Airport?

    In the last 5 days, the lowest price for a flight from John Wayne (Santa Ana) to Brussels Bruxelles-National Airport was $340 for a one-way ticket and $785 for a round-trip.

  • Do I need a passport to fly between John Wayne (Santa Ana) and Brussels?

    Yes, you’ll need a passport to travel to Brussels from John Wayne (Santa Ana).

  • Which aircraft models fly most regularly from John Wayne (Santa Ana) to Brussels?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from John Wayne (Santa Ana) to Brussels?

    Star Alliance is the only airline alliance operating flights between John Wayne (Santa Ana) and Brussels.

  • How does KAYAK find such low prices on flights from John Wayne (Santa Ana) to Brussels?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from John Wayne (Santa Ana) to Brussels.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from John Wayne (Santa Ana) to Brussels?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Brussels from John Wayne (Santa Ana) is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from John Wayne (Santa Ana) to Brussels?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Brussels with an airline and back to John Wayne (Santa Ana) with another airline. Booking your flights between John Wayne (Santa Ana) and BRU can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from John Wayne (Santa Ana) to Brussels?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Brussels from John Wayne (Santa Ana) up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Santa Ana to Brussels

 
See real verified KAYAK customer reviews for airlines flying from John Wayne (Santa Ana) to Brussels. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santa Ana to Brussels? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9926 reviews
7.7Boarding
7.3Comfort
7.1Entertainment
6.6Food
8.1Crew
Airline reviews

Great staff. Clean plane, but we were delayed for more than an hour due to maintenance issues and had to board another plane.

8.0 ExcellentNico, Jun 2026
LAX - HNL
Read more United Airlines reviews

Great staff. Clean plane, but we were delayed for more than an hour due to maintenance issues and had to board another plane.

WiFi didn’t exist , seats were super cramped, lights stayed on near my seat for a long time while others were dimmed, the food/trash/drink cart hit my shoulder at least a couple of times while moving, food options were down to just one option by the time it got to my row, the utensils were garbage (knife bent at a couple of places by the time I was done eating) the spoon was very flimsy plastic

I had enough leg room. The check in was smooth. Good food

Booked through Kayak Business, had a seat in middle and towards back due to booking rate, not comfortable.

The boarding timing needs to be improved. The flight was delayed again because it took way too long to board. I was already exhausted from sleeping at the airport and spending all day there due to delay from my previous flight that connected in Chicago.

Not a great experience. We paid for the upgrade for premium economy seats and seated ourselves in very comfortable seats. Someone came along with the same seat on their boarding pass. The aircraft had been changed and as a result we were booted out and sent further back to small uncomfortable seats. After complaining we were moved to emergency row seats, which gave us more leg room but the seats don’t recline. For people in our 70’s we found having to sit upright from California to NJ very uncomfortable. Not sure why they chose to move senior citizens instead of the two people that were allowed to take the more comfortable seats. Not happy.

Very poor the plane itself was really old, slight smell that couldn’t be named. I didn’t even get a boarding pass UNTIL AFTER clearing security! Even then, they said when I get to my connected flight I’ll get my 2nd boarding pass there! A bit ridiculous!

Due to one crew member not showing up to work, our flight was significantly delayed causing us to miss our connecting flight in Houston to Mississippi causing us to be delayed by more than 6 hours and missing our event all together. Very disappointing. All because ONE crew member called in sick. United did grant us a $15 meal voucher, which was a small but appreciated concession that I wasn’t able to use because I ordered my lunch and paid for it before applying the concession, and the staff said it was too late to use it. Ugh! We also had a TWO delay coming back from Mississippi, but that was on American Airlines and it was due to weather, so not their fault. Anyway, not at all impressed with United’s handling of our flight and the HUGE disappointment of missing our important family event for our 90 year old mother. All that money and all that stress and emotions for nothing. Having to wait the hour to bring an employee from LAX seemed like something that should not have happened. Why don’t you have a local back-up? Santa Ana is not a little airport in a rural area.

the head jack on my seat didn't work and the power outlet didn't work for my seat

Kayak, the site I went through to book our flight, sent very unclear emails about flight changes. Kayak was incredibly unhelpful in their communications with me about this, promising to work on resolving the issue, and failing to do so. As a result, I needed to get a hotel in Brussels and am now in the process of trying to get reimbursed. On the other hand, the flight personnel in Brussels were very helpful, taking time to look into the issue and determine if they could help. I am very grateful for them and have no problems with the airline. For Kayak, however, I will never use it again and will never recommend it to anyone, and will even discourage people who consider going through that site. My worst experience ever....

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