Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Paris (99% of total searches to La Defense). The next most popular destinations are Courbevoie (0%) and Neuilly-sur-Seine (0%). Searches for hotels in Puteaux (0%) are also popular.
KAYAK users have found double rooms in La Defense for as cheap as $23 (Paris) in the last 3 days. The average price is $347.