Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Boca Chica (94% of total searches to Santo Domingo). The next most popular destinations are Santo Domingo Este (5%) and Engombe (1%). Searches for hotels in Andres (0%) are also popular.
KAYAK users have found double rooms in Santo Domingo for as cheap as $48 (Pantoja) in the last 3 days. The average price is $83.