$100 Find Cheap Flights from Charlotte to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charlotte to South America departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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1 adult, Economy, 0 bags

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Cheap Flights from Charlotte to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$407
Bogotá
Bogotá1 stop$275
Buenos Aires
Buenos Aires1 stop$681
Sao Paulo
Sao Paulo2 stops$588
Rio de Janeiro
Rio de Janeiro2 stops$641
Santiago
Santiago2 stops$632
Cartagena
Cartagena1 stop$267
Quito
Quito2 stops$452
Guayaquil
Guayaquil1 stop$286
Cali
Cali1 stop$271
Cusco
Cusco3 stops$780
Pereira
Pereira3 stops$450
Montevideo
Montevideo2 stops$910
Barranquilla
Barranquilla1 stop$333
Santa Marta
Santa Marta2 stops$470
Lima
Lima1 stop$407
Bogotá
Bogotá1 stop$275
Buenos Aires
Buenos Aires1 stop$681
Sao Paulo
Sao Paulo2 stops$588
Rio de Janeiro
Rio de Janeiro2 stops$641
Santiago
Santiago2 stops$632
Cartagena
Cartagena1 stop$267
Quito
Quito2 stops$452
Guayaquil
Guayaquil1 stop$286
Cali
Cali1 stop$271
Cusco
Cusco3 stops$780
Pereira
Pereira3 stops$450
Montevideo
Montevideo2 stops$910
Barranquilla
Barranquilla1 stop$333
Santa Marta
Santa Marta2 stops$470

Book Cheap Charlotte to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charlotte to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charlotte to South America

Tue, Dec 2 - Wed, Dec 3
Spirit Airlines Logo
3:11 pm - 12:56 amCLT-MDE
9h 45m1 stop
Spirit Airlines Logo
2:05 am - 9:39 amMDE-CLT
7h 34m1 stop
$259Spirit Airlines
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Tue, Dec 2 - Thu, Dec 4
Spirit Airlines Logo
3:11 pm - 12:56 amCLT-MDE
9h 45m1 stop
Spirit Airlines Logo
2:05 am - 9:39 amMDE-CLT
7h 34m1 stop
$264Spirit Airlines
Find Deal
Sat, Feb 21 - Thu, Feb 26
Spirit Airlines Logo
7:00 am - 2:13 pmCLT-MDE
7h 13m1 stop
Spirit Airlines Logo
3:10 pm - 12:40 amMDE-CLT
9h 30m1 stop
$267Spirit Airlines
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Sun, Feb 8 - Wed, Feb 11
Multiple Airlines Logo
6:28 pm - 1:15 pmCLT-CTG
18h 47m1 stop
Multiple Airlines Logo
2:21 pm - 7:57 amCTG-CLT
17h 36m2 stops
$332Multiple Airlines
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Mon, Jan 26 - Thu, Jan 29
Multiple Airlines Logo
7:00 am - 2:15 pmCLT-CLO
7h 15m1 stop
Multiple Airlines Logo
6:52 am - 12:40 amCLO-CLT
17h 48m2 stops
$346Multiple Airlines
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Sun, Apr 12 - Tue, Apr 21
LATAM Airlines Logo
7:40 am - 8:00 pmCLT-UIO
13h 20m1 stop
LATAM Airlines Logo
9:11 am - 11:57 pmUIO-CLT
13h 46m2 stops
$550LATAM Airlines
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Wed, Mar 11 - Wed, May 6
GOL Logo
2:30 pm - 6:55 amCLT-GRU
39h 25m2 stops
GOL Logo
9:55 pm - 11:53 pmGRU-CLT
26h 58m2 stops
$633GOL
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Thu, Dec 4 - Tue, Dec 9
LATAM Airlines Logo
1:22 pm - 6:55 amCLT-SCL
15h 33m1 stop
LATAM Airlines Logo
11:30 pm - 1:28 pmSCL-CLT
15h 58m1 stop
$654LATAM Airlines
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Fri, Apr 3 - Sun, Apr 5
GOL Logo
4:15 pm - 10:20 amCLT-GIG
17h 05m2 stops
GOL Logo
12:30 pm - 9:55 pmGIG-CLT
34h 25m2 stops
$680GOL
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Thu, Dec 4 - Tue, Dec 9
Delta Logo
9:51 am - 6:35 amCLT-SCL
18h 44m2 stops
Delta Logo
8:15 am - 11:42 pmSCL-CLT
17h 27m2 stops
$714Delta
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Booking Insights

KAYAK's insights & trends for Charlotte to South America flights

Get data-powered insights and trends into flights from Charlotte to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Charlotte to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charlotte to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charlotte to South America is November, when tickets cost $693 (return) on average. On the other hand, the most expensive months are December and August, when the average cost of round-trip tickets is $869 and $848 respectively.

What’s the cheapest day of the week to fly from Charlotte to South America?

The average price of all round-trip flights from Charlotte to South America clicked on KAYAK for each day over the last 12 months.

For Charlotte to South America, Tuesday is the cheapest day to fly on average and Friday is the most expensive. Flying from South America back to Charlotte, the best deals are generally found on Tuesday, with Sunday being the most expensive.

How far in advance should I book a flight from Charlotte to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Charlotte to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Charlotte to South America, you should book around 5 weeks before departure, which saves you about 29% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 11 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$100
Best time to beat the crowds with an average 20% drop in price.
Most popular time to fly with an average 24% increase in price.
Flight from Charlotte to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charlotte to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charlotte to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charlotte to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charlotte to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charlotte to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charlotte to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charlotte to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charlotte to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally at night, when round-trip flights cost $685 on average. Morning departures are around 6% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $874.

Reviews of the top 5 airlines serving from Charlotte to South America

 
Need help choosing which airline to fly with from Charlotte to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8004 reviews
7.9Entertainment
7.9Comfort
7.3Food
8.1Boarding
8.5Crew
Airline reviews

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

8.0 ExcellentAnonymous, Nov 2025SFO - MSP
Read more Delta reviews

Our flight from SFO to MSP was right on time on 11/15/2025. No delays. As we approached MSP at about 8 pm, we circled in the air until 8:40 pm so I don't call that efficient for MSP. I think the captain should announce the delay and why. (as if we all don't know that we are just circling around the area, slowing down, speeding up, slowing down.) Thank you. Marilyn Fischer

Service in business class was not impressive. I ordered coffee with dinner and then watched other people get 2 refills before I got my 1 cup of coffee, and only after I pressed the attendant button overhead. Furthermore, the seats in the forward cabin need maintenance on this 737-800: the upholstery is detaching from the seat frame, at least on the backs of seats 1C, 1D.

Plenty of leg room, temperature was great and staff was excellent. Would do it more often.

The ticket agents in West Palm Beach on Friday afternoon Nov. 7th were incredible in getting us on an earlier plane to Atlanta during the government shutdown. Had the taken our original flight we would have missed our connection. She did this on her own, We didn't even have to ask, and she did it all with a smile and showing genuine concern that we would be taken care of. We are very grateful and thankful. We fly often, and now we will be sure to fly Delta.

Flight delayed then cancelled. Misplaced luggage. Still do not have. Rented car 1100 mile drive. I had to buy some overnight Hotels clothes toiletries gas food at my expense. Still not home. Not sure where luggage is. Over 4 hours on hold to Felta

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Just to drop my already labeled bag it took 50 minutes inline. Completely disappointed with Latam operation at GRU

Really bad experience – delayed for 6 hours without any notice, no food or drinks provided, and stuck in the horrible Cartagena airport.

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Boarding was confusing with a delayed flight because there was no English translation

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

I was not able to get on the flight due to delays out of Philadelphia. I arrived in MIA at 10:30pm and there was no one at the GOL Desk. Is there any flight credit available for this flight?

I have a hand injury and the flight attendant denied to help me with luggage, she said "she couldn't help me because I should manage my own way to put the luggage on the plane" SO RUDE

I had two around 6 hours flight and they did not even offer water to us.

Overall it was good. The food was not great quality and seats were very uncomfortable. But overall the staff was very friendly and helpful.

We flew with Avianca, some how they are not n sync, making the process a bit uncomfortable.

Unfortunately it was very disappointed experience. Our first flight our was delayed 2 hours, as a consequence we missed our connecting international flight. Customer server at Miami American Airlines was very disrespectful, gave us the worst replace itenarary for the next day that we had to spend 2 hours calling Gol to get a better itinerary otherwise we wouldn't make it on time to fulfill our trip purpose. We would have missed the reason to travel all the way to Brazil if we didn't change for a better itinerary. The worst thing is that our baggage was missing for 4 days. We had no cloths for all this time, plus the aggravation to locate our baggage. Nobody knew where our baggage was. We ended up picking it up at the airport when they said that they will bring them home. Unfortunately our experience was very dissatisfied.

Flight on time, check in and flight attendants courteous and helpful. Smaller plane for international flights, tight space, no comfortable.

the boarding staff were incredibly officious. our carry-on case was borderline within dimensions but staff were not prepared to show ANY flexibility even though many others with larger carry-on luggage were allowed to board. we were understandably furious but the staff were incredibly disrespectful. we called the supervisor who eventually agreed to look on board the plane to see if there was room for our case (one case between 2 of us) and reluctantly agreed to allow us on. The staff on board were excellent though and realized we had been treated badly and were very helpful both in finding a place for our case, some distance from our seats, and helping us to retrieve it when we landed. We are regular travelers on Gol and have Diamante status and had chosen the better Conforto + seats, so we expected better treatment from the ground staff. Also the cabins are of a size that will only fit 3 cases of normal size with a large gap of about 30cm of wasted space. If our case were deemed to be oversize, which I dispute, the extra 1cm would not have made the slightest difference.

I did not like the way that baggage fees were charged. When I signed up for the flight, I knew that there were bag fees. However, the bag fees were so confusing that it felt like I was paying for overweight bags rather than just for having brought a bag with me. Also, the bag fees were based on the pair of tickets rather than per person. It seems to me that it should be first bag fee for passenger 1 and then first bag fee for passenger 2. I eventually got away with only paying $100 for two bags, but it was a struggle to understand the process. As for the flight, the seats were the standard uncomfortable seats that are on most Boeing aircraft. The airline aims to accommodate the standard height people, so us tall people are stuck. There was never an option to upgrade for leg room. It did not appear that there were any seats on the whole plane that had a little more leg room to even try to get. Other than that, I completely ignored the food for this red eye flight. I am not one to eat "dinner" at 2 am. They did not offer any drinks in the morning before landing. I recommend that you bring a bottle of water on board.

Lost luggage, people are not very nice to help you , I was just instructed to fill out a baggage claim online, they were not helpful when I had additional questions after I completed the form on my phone.

Flight was delayed because of a bird strike. They had another plane available within 45 minutes.

You can plug your phone in & use their wifi to watch movies, etc, but the plane’s wifi was disconnected for most of the flight.

The trip was smooth but the crew were very abrupt, snatching things before finished and being quite snappy when asked questions.

Boarding: Boarding was a bit of a mess. Our tickets indicated "BC" for Business Class, but we and many others were confused as that was not indicated anywhere in the airport, so we didn't know when we're supposed to board. The airplane: The airplane was nice. However, we sat near the back of the business class cabin and the flight attendants and passengers from other cabins would constantly move the curtain (which was very loud), preventing me from fallling asleep on my 8 hour flight. The flight crew: Amazing, generally. However, they nearly forgot to serve breakfast to me. The flight food: I was able to select my meal for dinner, which was really good. Breakfast was a bit of a mess, however. The crew forgot to serve me breakfast until the last minute. Very little was available by the time they remembered. The entertainment: Paltry, underwhelming, and dated. Not one new movie was available. Bottom line: For the money, you might want to consider other options for your international business class flights.

Sat on the ground in Cincinnati for 50 minutes before deplaning

Overall fine, but the delay was annoying and the reasons for the delay were not communicated. The crew on board were phenomenal!

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Delayed because of weather in Nashville. I think God or some higher power generally has cursed me when it comes to flying out of Charlotte on American. I'm delayed pretty much everytime. We need Team Cobra Kai types to come in and "sweep the leg(s)" of the Charlotte ops people on principle. Don't let the sweet southern rocking chairs fool you, Charlotte is a sinkhole

Long 5 hour and 45 min flight and only one drink service and cookie snack

Newark airport grounded inbound flight and only announced when the flight was about to start taxing.

The flight was on time and the crew was very professional and accommodating. When other airlines are canceling flights Spirit is still flying with on time flights. I have no complaints and will continue to choose Spirit when it is the best option for me.

Very uncomfortable seat. Hard bar under cushion. Flight had no solution except to walk a around at times

Endless, trip oof my life, we still are in in plane waiting for getting off.after 3 hours delay. Not even a glass of water.

It was cheap. Spirit is what it is. I got to my destination and home safely. There was no food or entertainment without paying extra, which is fine. That’s why the flight was inexpensive.

Like: seats that don't move; fast boarding; engaging crew; low-prices; individual gate at LGA; access to restrooms at the gate Dislike: no water on the flight

No leg room. My knee was sore for a day.

It was better than expected. But there were two delays in taking off.

To be Honest they canceled my flight and didn't have other options. Until 4 says later and I have a 2yr old very disappointed.

The whole thing everything was poorly managed poorly handled spirit doent deserve to be in business period.

Nothing. It was delayed three times and then canceled and we had to drive 15 hours to get home and rent a car.

Everything you need to know for your flight to South America

Information on your arrival and departure airports