$101 Find Cheap Flights from Charlotte to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Charlotte to South America departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to South America

Travelers love KAYAK
41,299,237 searches in the past 7 days on KAYAK

Save 24% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Free to useThere are no hidden charges or fees.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Charlotte to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$388
Bogotá
Bogotá1 stop$291
Buenos Aires
Buenos Aires3 stops$768
Sao Paulo
Sao Paulo2 stops$627
Rio de Janeiro
Rio de Janeiro3 stops$630
Santiago
Santiago3 stops$665
Cartagena
Cartagena1 stop$267
Quito
Quito2 stops$499
Guayaquil
Guayaquil1 stop$307
Cali
Cali1 stop$301
Cusco
Cusco2 stops$830
Pereira
Pereira2 stops$459
Montevideo
Montevideo2 stops$764
Barranquilla
Barranquilla1 stop$468
Santa Marta
Santa Marta2 stops$860
Lima
Lima1 stop$388
Bogotá
Bogotá1 stop$291
Buenos Aires
Buenos Aires3 stops$768
Sao Paulo
Sao Paulo2 stops$627
Rio de Janeiro
Rio de Janeiro3 stops$630
Santiago
Santiago3 stops$665
Cartagena
Cartagena1 stop$267
Quito
Quito2 stops$499
Guayaquil
Guayaquil1 stop$307
Cali
Cali1 stop$301
Cusco
Cusco2 stops$830
Pereira
Pereira2 stops$459
Montevideo
Montevideo2 stops$764
Barranquilla
Barranquilla1 stop$468
Santa Marta
Santa Marta2 stops$860

Book Cheap Charlotte to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Charlotte to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Charlotte to South America

Thu, Dec 11 - Mon, Dec 15
Spirit Airlines Logo
2:58 pm - 1:09 amCLT-MDE
10h 11m1 stop
Spirit Airlines Logo
2:05 am - 2:03 pmMDE-CLT
11h 58m1 stop
$250Spirit Airlines
Find Deal
Fri, Dec 12 - Sat, Dec 13
Spirit Airlines Logo
2:58 pm - 1:09 amCLT-MDE
10h 11m1 stop
Spirit Airlines Logo
2:05 am - 9:39 amMDE-CLT
7h 34m1 stop
$259Spirit Airlines
Find Deal
Wed, Feb 4 - Thu, Feb 19
American Airlines Logo
7:55 am - 11:22 pmCLT-GYE
15h 27m1 stop
American Airlines Logo
3:31 pm - 9:14 amGYE-CLT
17h 43m1 stop
$503American Airlines
Find Deal
Wed, Feb 4 - Thu, Feb 19
American Airlines Logo
9:34 am - 11:22 pmCLT-GYE
13h 48m2 stops
American Airlines Logo
3:31 pm - 9:14 amGYE-CLT
17h 43m1 stop
$508American Airlines
Find Deal
Mon, Feb 9 - Wed, Mar 4
LATAM Airlines Logo
4:54 pm - 5:17 amCLT-UIO
12h 23m2 stops
LATAM Airlines Logo
11:45 pm - 8:42 amUIO-CLT
8h 57m1 stop
$519LATAM Airlines
Find Deal
Mon, Jan 12 - Fri, Jan 23
Delta Logo
2:25 pm - 9:35 pmCLT-UIO
7h 10m1 stop
Delta Logo
7:00 pm - 6:12 pmUIO-CLT
23h 12m2 stops
$548Delta
Find Deal
Sun, Apr 12 - Tue, Apr 21
LATAM Airlines Logo
7:40 am - 8:00 pmCLT-UIO
13h 20m1 stop
LATAM Airlines Logo
9:11 am - 11:57 pmUIO-CLT
13h 46m2 stops
$550LATAM Airlines
Find Deal
Sun, Apr 12 - Tue, Apr 21
Delta Logo
11:45 am - 8:00 pmCLT-UIO
9h 15m1 stop
Delta Logo
11:20 pm - 8:38 amUIO-CLT
8h 18m1 stop
$565Delta
Find Deal
Tue, Mar 10 - Sun, Mar 22
GOL Logo
2:32 pm - 10:15 amCLT-GIG
18h 43m2 stops
GOL Logo
6:00 am - 12:10 amGIG-CLT
19h 10m2 stops
$636GOL
Find Deal
Thu, Apr 23 - Mon, Apr 27
GOL Logo
2:40 pm - 7:00 amCLT-GIG
15h 20m2 stops
GOL Logo
6:00 am - 9:35 pmGIG-CLT
16h 35m2 stops
$640GOL
Find Deal
Booking Insights

KAYAK's insights & trends for Charlotte to South America flights

Get data-powered insights and trends into flights from Charlotte to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Charlotte to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Charlotte to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Charlotte to South America is March, when tickets cost $718 (return) on average. On the other hand, the most expensive months are December and August, when the average cost of round-trip tickets is $892 and $848 respectively.

What’s the cheapest day of the week to fly from Charlotte to South America?

The average price of all round-trip flights from Charlotte to South America clicked on KAYAK for each day over the last 12 months.

For Charlotte to South America, Tuesday is the cheapest day to fly on average and Friday is the most expensive. Flying from South America back to Charlotte, the best deals are generally found on Tuesday, with Sunday being the most expensive.

How far in advance should I book a flight from Charlotte to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Charlotte to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Charlotte to South America, you should book around 5 weeks before departure, which saves you about 28% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 11 weeks before departure.

Good to know

Low seasonSeptember
Cheapest flight$101
Best time to beat the crowds with an average 19% drop in price.
Most popular time to fly with an average 26% increase in price.
Flight from Charlotte to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Charlotte to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Charlotte to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Charlotte to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Charlotte to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Charlotte to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Charlotte to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Charlotte to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Charlotte to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally at night, when round-trip flights cost $685 on average. Morning departures are around 6% cheaper than evening flights, on average. The most expensive time of day to fly to South America is generally in the evening, which is peak travel time and where the average cost of a ticket is $874.

Reviews of the top 5 airlines serving from Charlotte to South America

 
Need help choosing which airline to fly with from Charlotte to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8001 reviews
7.9Comfort
7.9Entertainment
8.5Crew
8.2Boarding
7.3Food
Airline reviews

I truly love flying with Delta. They have always treated me with the upmost respect

10.0 ExcellentMAYRA, Nov 2025JFK - MIA
Read more Delta reviews

I truly love flying with Delta. They have always treated me with the upmost respect

Our flight attendant in FIRST CLASS was one of the worst I’ve ever had. She was not at all pleasant, nor particularly good at her service.

Everything went well and was good. Nothing exceptional, but no complaints either. Cheap seats are pretty comfortable.

Staff were friendly and happy. Delta could make sure passengers that don't have the app know of changes. Without Kayak I would not have known about the change of gate or the delay. Kayak was faster to notify me.

They ended up paying for the bag twice, but the counter wouldn't take my baggage receipt. Left it to me to resolve. Not sure how to resolve the issue.

The customer service before board was very rude and when I expressed my concerns about making the connecting flight she laughed and told me I bought the wrong ticket. I explained once it showed the flight was delayed it no longer let me change seats or anything. I was trying to upgrade to make sure I would get to the next gate on time.

Non stop on long haul is the way to go. Great experience

The aircraft interior is old and tired on this aircraft. The entertainment system never worked despite the crews attempt to reset the system.

The flight used a B767 with a very old interior from before 2014. The entertainment system did not work at all during the flight despite attempts to reset the system. It was like they flew this route just to be competitive.

Old plane and old configuration/seats but still comfortable for a morning flight

The assistance we received and the flight itself was wonderful. We will fly with LATAM airlines again, in the future.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Check in -- in business took over 30 mins as there was only one attendant. Boarding was also a mess. The seat was too narrow and was not working properly. Food was very bad and the entertainment very poor. Crew was very polite and helpful, in fairness.

we were missing our luggage, trying to find someone to have any empathy was pretty much not happening....

Poor handling of carry on luggage. We had a 8 hour stop in Santiago, are over 70 and, in spite of paying full fare they wanted to send carry on to luggage hold. No empathy. We had to show that several group 4/5 passengers were not sending their carry ons before they finally let Is keep them. Very poor .

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

Bought a ticket that included a bag and they still charged me to check it in, latam is the worst airline.

I have a hand injury and the flight attendant denied to help me with luggage, she said "she couldn't help me because I should manage my own way to put the luggage on the plane" SO RUDE

I had two around 6 hours flight and they did not even offer water to us.

Overall it was good. The food was not great quality and seats were very uncomfortable. But overall the staff was very friendly and helpful.

We flew with Avianca, some how they are not n sync, making the process a bit uncomfortable.

Unfortunately it was very disappointed experience. Our first flight our was delayed 2 hours, as a consequence we missed our connecting international flight. Customer server at Miami American Airlines was very disrespectful, gave us the worst replace itenarary for the next day that we had to spend 2 hours calling Gol to get a better itinerary otherwise we wouldn't make it on time to fulfill our trip purpose. We would have missed the reason to travel all the way to Brazil if we didn't change for a better itinerary. The worst thing is that our baggage was missing for 4 days. We had no cloths for all this time, plus the aggravation to locate our baggage. Nobody knew where our baggage was. We ended up picking it up at the airport when they said that they will bring them home. Unfortunately our experience was very dissatisfied.

Flight on time, check in and flight attendants courteous and helpful. Smaller plane for international flights, tight space, no comfortable.

the boarding staff were incredibly officious. our carry-on case was borderline within dimensions but staff were not prepared to show ANY flexibility even though many others with larger carry-on luggage were allowed to board. we were understandably furious but the staff were incredibly disrespectful. we called the supervisor who eventually agreed to look on board the plane to see if there was room for our case (one case between 2 of us) and reluctantly agreed to allow us on. The staff on board were excellent though and realized we had been treated badly and were very helpful both in finding a place for our case, some distance from our seats, and helping us to retrieve it when we landed. We are regular travelers on Gol and have Diamante status and had chosen the better Conforto + seats, so we expected better treatment from the ground staff. Also the cabins are of a size that will only fit 3 cases of normal size with a large gap of about 30cm of wasted space. If our case were deemed to be oversize, which I dispute, the extra 1cm would not have made the slightest difference.

I did not like the way that baggage fees were charged. When I signed up for the flight, I knew that there were bag fees. However, the bag fees were so confusing that it felt like I was paying for overweight bags rather than just for having brought a bag with me. Also, the bag fees were based on the pair of tickets rather than per person. It seems to me that it should be first bag fee for passenger 1 and then first bag fee for passenger 2. I eventually got away with only paying $100 for two bags, but it was a struggle to understand the process. As for the flight, the seats were the standard uncomfortable seats that are on most Boeing aircraft. The airline aims to accommodate the standard height people, so us tall people are stuck. There was never an option to upgrade for leg room. It did not appear that there were any seats on the whole plane that had a little more leg room to even try to get. Other than that, I completely ignored the food for this red eye flight. I am not one to eat "dinner" at 2 am. They did not offer any drinks in the morning before landing. I recommend that you bring a bottle of water on board.

Lost luggage, people are not very nice to help you , I was just instructed to fill out a baggage claim online, they were not helpful when I had additional questions after I completed the form on my phone.

They are not ready for international flights, poor service and food, no screen info on the seat.

Flight was delayed because of a bird strike. They had another plane available within 45 minutes.

You can plug your phone in & use their wifi to watch movies, etc, but the plane’s wifi was disconnected for most of the flight.

The trip was smooth but the crew were very abrupt, snatching things before finished and being quite snappy when asked questions.

Boarding: Boarding was a bit of a mess. Our tickets indicated "BC" for Business Class, but we and many others were confused as that was not indicated anywhere in the airport, so we didn't know when we're supposed to board. The airplane: The airplane was nice. However, we sat near the back of the business class cabin and the flight attendants and passengers from other cabins would constantly move the curtain (which was very loud), preventing me from fallling asleep on my 8 hour flight. The flight crew: Amazing, generally. However, they nearly forgot to serve breakfast to me. The flight food: I was able to select my meal for dinner, which was really good. Breakfast was a bit of a mess, however. The crew forgot to serve me breakfast until the last minute. Very little was available by the time they remembered. The entertainment: Paltry, underwhelming, and dated. Not one new movie was available. Bottom line: For the money, you might want to consider other options for your international business class flights.

Sat on the ground in Cincinnati for 50 minutes before deplaning

Overall fine, but the delay was annoying and the reasons for the delay were not communicated. The crew on board were phenomenal!

Boarding was very efficient. Everyone got on board and we got on our way very quickly. It was frustrating that the entertainment app was not functioning properly. I was not able to activate some of the movies offered. The crew on this flight appears to be pretty grumpy. They had no smile on their faces. I felt like they were doing us a favor for being there.

Delayed because of weather in Nashville. I think God or some higher power generally has cursed me when it comes to flying out of Charlotte on American. I'm delayed pretty much everytime. We need Team Cobra Kai types to come in and "sweep the leg(s)" of the Charlotte ops people on principle. Don't let the sweet southern rocking chairs fool you, Charlotte is a sinkhole

Long 5 hour and 45 min flight and only one drink service and cookie snack

Newark airport grounded inbound flight and only announced when the flight was about to start taxing.

The Hawaiian lady that boarded me was rude and the one help me a the ticket counter was rude

My experience was terrible. They cancelled my flight twice. They kept delaying it and leading me on, acting like the flight was going to go when it never had a chance. I missed out on valuable family time because of spirit and I won’t be flying with them again.

Prices for bags are extremely expensive and if you go higher on weight, the charge is ridiculous.

The flight was cancelled at the last minute. Will never fly Spirit again. Without a doubt the worst airline around.

My flight was delayed several times and eventually cancelled. Then the re-booked flight for 8pm was delayed multiple times over, and eventually it would have forced me to be at the airport for 9 hours. I accepted a rebook for the following day, fortunately I was able to stay with my friend again in New York, but if I didn’t have him as a resource it would have been much more upsetting.

Horrible, delay after delay due to our plane needing fuel.

Rough landings but comfortable and affordable if you can pack light

the plane was not full so the flight attendant had me move to an empty row which made for a good flight. The software for logging on and booking and confirming the flight is much too cumbersome.

Always comes in handy when I want a quick weekend getaway.

For the price I could have taken a “name brand” airline. No drink no snack and constant emails trying to get addition money for EVERYTHING other airlines include in the price. It looks cheaper but it’s Judy bait and switch and emails non stop!

Everything you need to know for your flight to South America

Information on your arrival and departure airports