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Find cheap flights from Chicago O'Hare Airport to South America from $110

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from O'Hare Intl to South America departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Fri 6/7
Fri 6/14

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Best South America Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima2 stops$477
Bogotá
Bogotá2 stops$221
Medellín
Medellín1 stop$229
Sao Paulo
Sao Paulo3 stops$582
Cartagena
Cartagena1 stop$244
Santiago
Santiago2 stops$617
Rio de Janeiro
Rio de Janeiro2 stops$681
Quito
Quito2 stops$354
Guayaquil
Guayaquil1 stop$265
Cali
Cali1 stop$265
Cusco
Cusco3 stops$569
Pereira
Pereira2 stops$372
Barranquilla
Barranquilla1 stop$203
Montevideo
Montevideo2 stops$616
Caracas
Caracas3 stops$668
Santa Marta
Santa Marta2 stops$335

Good to know

Low season

October

High season

December

Cheapest flight

$110
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly with an average 43% increase in price.
Flight from Chicago O'Hare Airport to Medellín Jose Maria Cordova Intl

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Chicago O'Hare Airport to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago O'Hare Airport to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago O'Hare Airport to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to South America from Chicago O'Hare Airport is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago O'Hare Airport to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to South America with an airline and back to Chicago O'Hare Airport with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago O'Hare Airport to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to South America from Chicago O'Hare Airport up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • Morning departure is around 34% more expensive than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 5 airlines serving from O'Hare Intl to South America

 
Need help choosing which airline to fly with from O'Hare Intl to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10789 reviews
7.4Food
8.0Entertainment
7.9Comfort
8.2Boarding
8.6Crew
Airline reviews

West Jet has a horrible boarding process and the seats have no cushion.

4.0 OkayDouglas, May 2024MSP - YEG
Read more about Delta reviews

West Jet has a horrible boarding process and the seats have no cushion.

Everything went smoothly. I didn’t like that when I booked in the main cabin my wife and I weren’t seated together. One would think when booking on an option that allows picking your seat. They would put you and your travel partner together. Had to call to get it sorted. They did fix.

The gate area was incredibly short staffed, with one representative manning 4-5 flights, which caused a 3 hr delay in boarding even though the plane was all ready to leave. Other flights also were delayed because of this. The flight crew was awesome and I feel bad for the only gate worker on call, but Delta needs to hire more employees.

Very frustrated with boarding gate crew. She announced the plane was small and they would be limiting us to one item to carry on. Not a problem for me as I understand the tiny planes have limited space!! Not the case here! It was a rather large plane and had plenty of room for bags! So because I don’t want to be one of “those people” who ignores the request to check a carry on I did so asking if I would be able to pick it up at the bottom of the ramp on arrival in Knoxville to which she responded “yes”! Then I watched as every other passenger held onto their 2 items and boarded!! Then when we arrived in Knoxville our 2 carry ons had been put with all the other luggage and we had to go to baggage pick up and wait for all the big checked bags to come off the carousel! So she lied!! Frustrating. Next time I won’t be so nice!

It was a good experience except when boarding a female flight attendant did not go out of her way to assist my teenage daughters in finding space for their carry-ons after their compartments were full.

On time departure, smooth trip, flight attendant told through passengers the gate we would arrive at and the gate our outbound flight was departing from. Early arrival

Checking in at the airport the agent only booked the first keg of my trip and had my checked luggage going to the airport with a layover! Never was issued a boarding pass for the second leg or received sticker fir my checked bag. All was well in the end! Delta agents helped to resolve the situation!!!

Delayed due to an ill passenger after loading. Not preventable on Delta's part. Was in first class. The seats are becoming worn and detaching from their velcro attachments. Only got snacks on flight. The attendant was not the friendliest.

I would fly again the whole experience was great. The only feed back I can give that they don't do that American Airlines does is the crew there is more humorous with boarding and thank their passengers. It makes it more fun to fly with them. I would however fly Delta again.

Big plane, long flight, absolutely no leg room and basically non existent air! I am 5”4’ and always travel Main Cabin, I was miserable on this plane and could barely move when we arrived in Cabo due to the cramped leg area!

Copa performed as expected for the amount of money I was willing to spend for the flight; it wasn’t exceptional but it was not bad in any way either. The crew was good; friendly and straightforward. The food was airplane food, so no expectations there and the entertainment was lacking but that was my fault for owning an IPhone with a charging port that’s not compatible with the rest of the world. I’d fly Copa again.

Left my bags in origin city on a business class ticket , spent about 2-3 days in the same clothes plus the flight .

the planes are not modern there are no phone chargers

As usual, the flight with normal legroom was not very comfortable, but the second flight was much better because we had paid for extra legroom. It was very nice to check our bags without an extra fee.

LOCKED MY BAG WITHOUT CONSENT. Had to have my zippers cut upon arrival in Costa Rica.

Pros: "The seats in economy were confortable. The best thing was Copa gave us seats in the second line and my family traveled together."
Cons: "Coffe service could better the experience"
Pros: "The crew was very interested on help and attentive with the passengers. But the seat wasn't comfortable. The design of the cushion is not the best to be seating"
Pros: "You were on time, that is the most important thing in a fly"
Cons: "You could improve your entertainment, you are not a cheap company"
Pros: "That there was seltzer"
Cons: "The management of preparing the flight and plane so that it was ready for the trip!!"
Pros: "Copa was convenient and easy. Very easy boarding process and I appreciated the day flight."
Cons: "This is a business class that is equivalent to a US carrier domestic first class. Good seats, not lay flat but wide on my 737-800. The food and service emulated say American Airlines Domestic 1C as well. Everything was just good enough, and much cheaper that international business on the majors."

Everything was as you would expect in coach - fine. Flight was close to on time.

No air in the middle rows. Had a hard time breathing. Was dying of heat.

Horrific checkin procedure with neither Delta nor Latam figuring out how to check me in. 4 hrs on customer support with both and both airlines pointing to each other who should do checking. I was not checked in until morning of flight, which for international flight is concerning.

It was a good experience, the flight was a little too long & the food was ok

the flight from Boston to Curitiba was on time actually 30 minutes earlier. latam was not able to unload the luggage for custom checkup in Sao Paulo ii took two and half hours . i missed the flight to Curitiba spend the night in hotel and then flying in the morning to Curitiba

Tough flight with turbulence… I was told by a fellow passenger that it is common. Nonetheless, very stressful. Cordial staff.

Very unprofessional staff in the checking and boarding. There was no space for my carry-on bag, which is understandable for a full flight. However, the rudeness in answering my questions about my bag were unnecessary. Shaming and threatening a passenger to be left behind was something I had never experienced (I am 57 years old and a Skymiles member) before. At a minimum, the boarding staff (Krystal Mejia and her manager Dee) should undergo further training on cultural sensitivity and professional skills on speaking with passengers. Krystal, just because I have dark hair and “look Latina” does not mean I can speak Spanish. Your assumption and threatening words until the very ending of my boarding (door of the airplane) were not only unnecessary and stressful but something that a passenger should not experience before boarding.

Check in of my luggage which needed to be paid for was excellent. Thanks to Nora

This airline is full of junk fees. After paying to get my kids to sit with me, we were asked at the gate to check in our roller bags and pay $40 for each one. Peruvian passengers all took their roller bag in the plane. I don’t appreciate airlines who spot the gringos to tax them more.

The flight from PDX to New York was cancelled, and I got rebooked one day later. Because of this I missed a meeting at my final destination, EZE. I now need to stay longer in Argentina, and was told the tariff difference was $780 plus $150 penalty! I am not using my return ticket, and have purchased a one way ticket EZE-PDX for $606 with another airline. SHAMEFUL

It was spectacular. I had basic Economy and was given so much space and their seats lean back so far. Staff was superb, food was superb, everything was superb, Finnair is Fantastic.

Good flights. Departure and arrivals were on time. DFW was a little problematic in that the Skytrain without prior notice bypassed the Echo terminal so that delayed my arrival at my connecting flight.

Because I can’t stand very long in one place, I was allowed to reword.

We were delayed bc ground crew gave the flight crew the wrong paperwork. We taxiied to the runway then back to the gate to get the correct paperwork that no one bothered reviewing the first time we pushed back. Boarding was rude and stressful like it always is. Gate agents and flight attendants are all over 55 years of age, embittered by years of underpayment From AA leading to their passive agressive bitchiness for no reason.

Boarding time was easy & quick. Crew was excellent. In-flight entertainment was great/easy. Seats are too small and not enough room between rows: felt like a sardine/very cramped.

5 hour flight - full flight - not enough room to use my computer - slightly delayed - Admirals club was excellent quality food, drink made up for flight seating. No food offerred on flight, you ahd to prebook.

Excellent- plan was barely populated. I cannot remember a flight where I was able/encouraged to stretch out!

Great flight. Boarding was efficient and quick. On time departure and smooth flight. Flight arrived early at destination. Good experience.

Had technical issue which delayed the flight period. Flight crew knew there was 5 passengers that the connecting flight was within 15 minutes once at the gate. Rather than identify the 5 passengers to assure they got first. The flight attended mentioned it but didn't assist to assure passengers with connecting flights off first. This caused a hardship and our party of 3 missed the connecting flight.

I don't like that I have to pay if I want extra leg room. The seats are so expensive; I sit in normal seats and my legs and knees cramp the entire flight. I never feel comfortable on AA flights.

For it to have left on time! Instead of two hours early with zero notice

Flight kept delayed from morning to late afternoon so I had to make other arrangements

Crew was nice, explained emergency protocol very well. Flight took off and arrived on time. Pilot explained the small delay that occurred with docking and providing updates. I would definitely fly spirit again.

Terrible… missed our flight due to ridiculously long time to go thru baggage check-in!

The crew was not great or professional. It seemed like they didn't really want to be there. A true lack of effort for accommodating customers.

Everything was really good but the seats are not very comfortable.

I paid for WiFi, but it (WiFi) was very very slow, will never take again! Impossible open Utube 😤😤😤

I had no legroom, although I paid for extra legroom. I could barely put my bag in front of my feet and under the seat. The Wi-Fi was horrible. In fact the flight attendant said that they had to reboot it and see if it was going to work and never did.

The guy with severe body odor sat next to me. For the whole duration of the flight it was a torture. The airline should have better policy on limiting people with bad body odor to board the flight. Passengers should not be the ones to endure bad odor for the whole duration of the flight. The airline should be e the one to ensure decent air quality for ever passenger.

Overall it was a miserable experience... I will never fly spirit for more than a 3 hour flight or overnight.

Book cheap flights from Chicago to South America

Recent round-trip flight deals

5/29Wed
2 stopsSpirit Airlines
17h 20mORD-BOG
6/5Wed
1 stopSpirit Airlines
8h 52mBOG-ORD
$221
6/5Wed
1 stopSpirit Airlines
18h 31mORD-BOG
8/20Tue
1 stopSpirit Airlines
19h 23mBOG-ORD
$226
9/1Sun
1 stopCopa Airlines
15h 04mORD-CTG
9/4Wed
1 stopCopa Airlines
14h 26mCTG-ORD
$312
5/18Sat
1 stopDelta
14h 05mORD-BOG
6/8Sat
1 stopDelta
17h 16mBOG-ORD
$317
5/18Sat
1 stopLATAM Airlines
14h 05mORD-BOG
5/26Sun
1 stopLATAM Airlines
9h 15mBOG-ORD
$318
5/18Sat
2 stopsDelta
19h 47mORD-BOG
5/25Sat
1 stopDelta
9h 08mBOG-ORD
$322
10/1Tue
2 stopsAmerican Airlines
10h 23mORD-BOG
10/14Mon
2 stopsAmerican Airlines
12h 10mBOG-ORD
$323
6/28Fri
1 stopCopa Airlines
17h 44mORD-CTG
7/2Tue
1 stopCopa Airlines
14h 27mCTG-ORD
$337
6/1Sat
1 stopAmerican Airlines
8h 10mORD-BOG
6/4Tue
1 stopAmerican Airlines
19h 09mBOG-ORD
$340
8/12Mon
2 stopsLATAM Airlines
22h 05mORD-BOG
8/22Thu
2 stopsLATAM Airlines
16h 59mBOG-ORD
$343

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Recent one-way flight deals

6/8Sat
2 stopsSpirit Airlines
18h 16mORD-MDE
$110
6/12Wed
2 stopsSpirit Airlines
19h 26mORD-BOG
$110
5/15Wed
1 stopCopa Airlines
9h 06mORD-MDE
$143
5/17Fri
1 stopCopa Airlines
9h 31mORD-BOG
$143
5/13Mon
1 stopAmerican Airlines
12h 05mORD-UIO
$144
5/13Mon
1 stopDelta
14h 05mORD-BOG
$146
5/17Fri
2 stopsLATAM Airlines
14h 32mORD-BOG
$147
10/2Wed
1 stopAmerican Airlines
12h 28mORD-UIO
$149
5/17Fri
2 stopsLATAM Airlines
14h 32mORD-BOG
$152
6/8Sat
1 stopDelta
27h 21mORD-UIO
$188

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Last minute flights from O'Hare Intl to South America

Last minute flight, train and bus deals

5/11Sat
multi-stopCopa Airlines
14h 59mORD-BOG
5/13Mon
multi-stopCopa Airlines
15h 48mBOG-ORD
$315
5/11Sat
multi-stopLATAM Airlines
7h 50mORD-BOG
5/21Tue
multi-stopLATAM Airlines
9h 05mBOG-ORD
$317
5/9Thu
multi-stopDelta
14h 05mORD-BOG
5/21Tue
multi-stopDelta
10h 37mBOG-ORD
$318
5/11Sat
multi-stopAmerican Airlines
12h 05mORD-BOG
5/21Tue
multi-stopAmerican Airlines
13h 09mBOG-ORD
$320
5/13Mon
multi-stopDelta
18h 18mORD-BOG
5/22Wed
multi-stopDelta
16h 50mBOG-ORD
$322
5/13Mon
multi-stopUnited Airlines
11h 15mORD-BOG
5/22Wed
multi-stopUnited Airlines
24h 28mBOG-ORD
$324
5/10Fri
multi-stopSpirit Airlines
18h 37mORD-BOG
5/31Fri
multi-stopSpirit Airlines
9h 19mBOG-ORD
$335
5/13Mon
multi-stopUnited Airlines
11h 15mORD-BOG
5/17Fri
multi-stopUnited Airlines
14h 03mBOG-ORD
$337
5/12Sun
multi-stopAmerican Airlines
10h 40mORD-BOG
5/16Thu
multi-stopAmerican Airlines
13h 09mBOG-ORD
$370
5/10Fri
multi-stopSpirit Airlines
18h 59mORD-CTG
5/13Mon
multi-stopSpirit Airlines
28h 18mCTG-ORD
$506

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