$116 Find Cheap Flights from Chicago O'Hare Airport to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from O'Hare Intl to South America departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
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Best South America Flight Deals from O'Hare Intl

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$412
Bogotá
Bogotá1 stop$282
Medellín
Medellín1 stop$300
Sao Paulo
Sao Paulo1 stop$470
Rio de Janeiro
Rio de Janeiro1 stop$530
Cartagena
Cartagena1 stop$282
Santiago
Santiago2 stops$564
Quito
Quito1 stop$386
Cali
Cali1 stop$275
Guayaquil
Guayaquil1 stop$372
Cusco
Cusco1 stop$582
Georgetown
Georgetown1 stop$437
Pereira
Pereira1 stop$420
Montevideo
Montevideo2 stops$892
Barranquilla
Barranquilla1 stop$303
Santa Marta
Santa Marta1 stop$458
Lima
Lima1 stop$412
Bogotá
Bogotá1 stop$282
Medellín
Medellín1 stop$300
Sao Paulo
Sao Paulo1 stop$470
Rio de Janeiro
Rio de Janeiro1 stop$530
Cartagena
Cartagena1 stop$282
Santiago
Santiago2 stops$564
Quito
Quito1 stop$386
Cali
Cali1 stop$275
Guayaquil
Guayaquil1 stop$372
Cusco
Cusco1 stop$582
Georgetown
Georgetown1 stop$437
Pereira
Pereira1 stop$420
Montevideo
Montevideo2 stops$892
Barranquilla
Barranquilla1 stop$303
Santa Marta
Santa Marta1 stop$458

Cheap Flights from O'Hare Intl to South America

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from O'Hare Intl to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from O'Hare Intl to South America

Wed, Sep 24 - Wed, Oct 1
Spirit Airlines Logo
5:05 am - 12:23 pmORD-CTG
7h 18m1 stop
Spirit Airlines Logo
1:29 pm - 10:48 pmCTG-ORD
9h 19m1 stop
$282Spirit Airlines
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Tue, Sep 9 - Wed, Sep 10
Spirit Airlines Logo
5:05 am - 1:00 pmORD-BOG
7h 55m1 stop
Spirit Airlines Logo
1:57 pm - 10:48 pmBOG-ORD
8h 51m1 stop
$282Spirit Airlines
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Fri, Sep 26 - Wed, Oct 1
Copa Airlines Logo
3:07 pm - 8:41 amORD-CTG
17h 34m1 stop
Copa Airlines Logo
6:20 am - 12:22 amCTG-ORD
18h 02m1 stop
$290Copa Airlines
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Fri, Aug 22 - Fri, Aug 29
American Airlines Logo
8:41 pm - 12:25 pmORD-CTG
15h 44m2 stops
American Airlines Logo
3:10 pm - 11:57 pmCTG-ORD
8h 47m1 stop
$291American Airlines
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Thu, Aug 14 - Thu, Aug 21
American Airlines Logo
9:20 am - 9:17 pmORD-BOG
11h 57m2 stops
American Airlines Logo
2:10 pm - 11:57 pmBOG-ORD
9h 47m1 stop
$295American Airlines
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Tue, Sep 9 - Sat, Oct 11
LATAM Airlines Logo
9:47 am - 7:15 pmORD-BOG
9h 28m1 stop
LATAM Airlines Logo
2:55 pm - 11:53 pmBOG-ORD
8h 58m1 stop
$316LATAM Airlines
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Tue, Sep 16 - Fri, Sep 26
LATAM Airlines Logo
9:50 am - 8:10 pmORD-BOG
10h 20m2 stops
LATAM Airlines Logo
10:15 am - 8:40 amBOG-ORD
22h 25m2 stops
$320LATAM Airlines
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Fri, Sep 19 - Wed, Sep 24
Copa Airlines Logo
3:07 pm - 10:58 pmORD-CTG
7h 51m1 stop
Copa Airlines Logo
6:20 am - 12:21 amCTG-ORD
18h 01m1 stop
$325Copa Airlines
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Fri, Nov 7 - Tue, Nov 11
Avianca Logo
1:35 pm - 7:48 amORD-CTG
17h 13m1 stop
Avianca Logo
9:06 pm - 12:15 pmCTG-ORD
16h 09m1 stop
$336Avianca
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Mon, Oct 27 - Wed, Nov 5
Avianca Logo
2:35 pm - 12:40 amORD-GIG
32h 05m1 stop
Avianca Logo
1:45 am - 12:15 pmGIG-ORD
13h 30m1 stop
$577Avianca
Find Deal
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KAYAK's insights & trends for O'Hare Intl to South America flights

Get data-powered insights and trends into flights from O'Hare Intl to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Chicago O'Hare Intl Airport to South America flight route?

The cheapest price for flight routes found by users searching on KAYAK in the last 2 weeks for round-trip flights from Chicago O'Hare Intl Airport to South America.

The cheapest ticket to South America from Chicago O'Hare Intl Airport found in the last 72 hours was to Bogotá, at $380 round-trip. The most popular route is from Chicago O'Hare Intl Airport (ORD) to Bogotá (BOG), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $380.

Can I save money by flying with a layover from Chicago O'Hare Intl Airport to South America?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 3 stops layover the cheapest option at $963 on average.

What is the cheapest month to fly from Chicago O'Hare Intl Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago O'Hare Intl Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago O'Hare Intl Airport to South America is April, when tickets cost $526 (return) on average. On the other hand, the most expensive months are December and August, when the average cost of round-trip tickets is $907 and $711 respectively.

What’s the cheapest day of the week to fly from Chicago O'Hare Airport to South America?

The average price of all round-trip flights from Chicago O'Hare Intl Airport to South America clicked on KAYAK for each day over the last 12 months.

For Chicago O'Hare Airport to South America, Wednesday is the cheapest day to fly on average and Saturday is the most expensive. Flying from South America back to Chicago O'Hare Airport, the best deals are generally found on Sunday, with Monday being the most expensive.

How far in advance should I book a flight from Chicago O'Hare Intl Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago O'Hare Intl Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago O'Hare Intl Airport to South America, you should book around 2 weeks before departure. For the absolute cheapest price, our data suggests you should book 13 weeks before departure.


Good to know

Low seasonOctober
High seasonDecember
Cheapest flight$116
Best time to beat the crowds with an average 10% drop in price.
Most popular time to fly with an average 40% increase in price.
Flight from Chicago O'Hare Airport to Cartagena

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Chicago O'Hare Airport to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago O'Hare Airport to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago O'Hare Airport to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago O'Hare Airport to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago O'Hare Airport to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago O'Hare Airport to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago O'Hare Airport to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago O'Hare Airport to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the afternoon, when round-trip flights cost $599 on average. Morning departures are around 4% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally at night, which is peak travel time and where the average cost of a ticket is $758.

Reviews of the top 5 airlines serving from O'Hare Intl to South America

 
Need help choosing which airline to fly with from O'Hare Intl to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1807 reviews
7.6Boarding
6.7Food
7.4Comfort
7.0Entertainment
8.1Crew
Airline reviews

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

6.0 GoodDiane, Jul 2025ATL - PDX
Read more LATAM Airlines reviews

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

I was in the last row and they sent me to check in my luggage last minute after boarding. I had to go through the crowd.

Our flight was cancelled and it took them 5 hours to reschedule and the next morning they said we still didn’t have a new ticket.

I travel often with LATAM, it never disappoints me. The service is great, nice crew, latest and some classic movies. I got 3 small meals, cannot complaint. I’ll definitely travel again with them.

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Delta has an outstanding service. They are courteous and punctual most of the time. The flight departed a half hour late but we arrived 15 minutes early.

Although the flight is goof and the crew is good, the way the airline charges you for every service is ridiculous.

Plane never left the ground. Mech issues - entire trip was rerouted through united.

The flighr attandants were very rude they ignored me didnt offer me anything to drink throughoit the 4 hour flight i feel i was targeted and ignored because i was a darkskin latino man.

Very happy with my flight. I would definitely recommend it.

Did upgrade, travel in business it was great (more room I could sleep)

We had a five hour layover in the way home from Colombia. I read the "bout your flight" email carefully before we checked bags. We had to go through security right at the gate. Almost lost our ground coffee because that airport only allows 16 ounce of coffee and we had 18. I've been to 48 countries and never heard of a coffee restriction. I can't follow a rule I don't know about. I requested they bring our coffee to our checked luggage. Instead tey gate checked our bag for free. Back to planning transfers in Dallas I guess

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

Enforce the boarding process by group numbers. Tell people to stay seated during the meal/drink distribution. It took forever to get food and drinks because people would not stay out the isle and let the crew do their jobs. Everyone wanted to go to the bathroom forcing the crew to enter and leave the isle constantly so people can pass. Tell people to keep their electronics off speaker mode. No one wants to hear phone conversations and music playing.

Placed us in the last rear row of the plane so could not recline seats because of the rear wall, and also made it more of a tight space when the passenger in front reclined their seat. While understand seat assignments, every passenger should be afforded a reclining seat. The odor control scent from the restrooms was overwhelming strong. My wife and I could not deal with it, and she suffered a terrible headache as a result. I kept getting hit by the crew since I was on the ilse seat. No apologies, nothing. They made me feel like I was supposed to take the beating for a 3 hr flight.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

The flight was delayed twice and I could not speak with anyone at the airport about checking in. The phone number to Copa - the customer service agents were polite. They are just limited at helping because they are not at the airport

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

It was great, I’m very grateful for the pilots and crew flight attendants for everything.

Evidently, my seat had the only broken TV. I couldn’t plug it in, get it to come on, or watch anything, and of course, no one could fix it while we were on the plane. The service was good and the boarding was quick

The boarding of took of late.The presentation of the food was horrable as was the tast of the food was cold and tastless.

Delay and keep changing gates. I have to run around from B to C then to E.

I was charged for my daughters bag when I am supposed to receive two free checked bags with my United Explorer card.

The schedule to Moline changed 5 times. The gate changed 6 times. That is a pathetic way to run an airline. No wonder that no one in our company flies on United Express to or from Moline. Changes happen most of the time. I learned my lesson on this trip…never again!

Flight was great. Efficient boarding. Short flight. Early arrival. Friendly flight crew. The entertainment system did not work well. Could not access it until the aircraft reached 10K feet or more. Lots of glitches.

A bit rush for transit. Food and entertainment are not available

Boarding was a little difficult. The gate area at O'Hare was very small and crowded due to multiple gates in the area. Could not hear the intercom, so had to rely on signage to see when my group was boarding and the signage was blocked by passengers standing in the gate. Flight was great and we arrived in Montreal on time.

Smooth boarding process. Early departure, smooth flight, early arrival. The entertainment package has very good recent movie options. The flight crew were friendly and professional.

Amazing food, great staff, with one noticable detail missing ...but no seat entertainment in any of aircraft ...I am not a fan

I wish American Airlines would change the airline industry by loading the plane back to front instead of front to back. Planes would board so much more smoothly and quickly.

I have long legs, my foot was out in the aisle and when a flight attendant came walking by and I didn't notice, instead of saying "excuse me" or anything like that, she kicked my foot. Extremely rude

Excellent! The gate agents were kind enough to rebook me on an earlier flight saving me from a 6 hour layover. Even my luggage made it despite the fact that the connection was technically too narrow. The flight itself was very comfortable, roomy, and clean. Plenty of space for my carryon items with plugs to charge my phone. After a long international flight of 14 hours, this was an excellent way to end my travels!

Great experience. Flight boarded easily. Departed early. Smooth flight. Great arrival in DC--almost no taxing! Almost direct to gate from runway. Crew was terrific. Same cookies and beverages in main cabin. I did not use the entertainment system on this flight.

This particular flight wasn't very full at the back, so there were three seats available for spreading out and getting relatively comfortable

Most of the delay was due to weather which is not what was at issue here. One delay was due to a missing flashlight and in the end the flashlight was actually found on the plane. The entertainment system is very limited. Live TV options offer only a few channels that are not very appealing. Boarding and deplaning are always difficult. It just takes too much time to get on and off the plane. On the plus side, I missed my connecting flight, but was easily able to book a later flight from the app while enroute.

You were more on time than United. I'm so over united delays.

The meals were mediocre and the alcohol selection was poor. I enjoyed the selection of movies and other entertainment.

I chatted with the captain before the flight, and similarly during the welcome announcement, he warned of a turbulent flight that may impact the in-flight service. However, once at altitude, he announced that the weather changed and he immediately turned off the seatbelt sign. But it appeared the cabin crew had already decided to take off this flight. They remained seated and then just chatted in the galley. The flight was fully catered, but only first class received service.

Boarding was excessively slow. They do it by groups in a way that it doesn’t make sense. After business class , ppl that need assistance and any other priority group they should have ppl board from the back to the front. First rows 20+. Then 15+. Then 10, etc. having ppl sitting in the back board last makes no sense. The libe backame long as soon as ppl on rows 10 or so where told to board. The line went all the way up the ramp and tunnel for 25 mins.

Seats are very tight even in Plus, no complimentary snacks or beverage

I receive a service for what I pay, so it is fair.

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

Excellent flight and one of the smoothest landing I’ve ever experienced

There isn't much space in-between seats and even water needs to be paid for during the flight.

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

Boarding was somewhat confusing in that the wrong messages were being displayed at the gate. It was somewhat annoying that I got off one flight and straight onto another (from the same gate), but in between they re-checked my hand luggage and made me get rid of my water (which they charge for on the plane). I was sitting in their 'Plus' seating, but the leg room was still too small to be able to sit square. The food options on the flights are pretty cheap quality (but not price). They got me from 'A' to 'B' on-time and for a relatively good price, but the experience itself was below average.

Lounge for business was closed. Boarding was rush and stand by. Seat for business is just the middle seat blocked and some more leg room.

Flew with our two children. Paid $380 to check two bags (one was overweight). They then left the bags behind on Sunday, December 21st, with all our family’s clothes and family Christmas presents. When we arrived at our destination they told us the bags had not arrived, and they thought (but didn’t know) they were still in Boston, but that there’d be a flight the next day and the bags would arrive the next day. The next day we found out there was no flight, now we’re hoping we get our bags before we fly back out. Meanwhile, trying to get any engagement or accurate information is a waste of time. The folks at the call center are just gatekeepers, who can’t connect with any departments that actually do things to solve a problem. Getting information is made deliberately difficult. My biggest regret is that I’ve had a number of awful experiences with Avianca traveling between the US and Colombia, and still let myself get suckered into buying these tickets because the schedule was great. Never again.

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