$79 Find Cheap Flights from Chicago O'Hare Airport to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from O'Hare Intl to South America departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from O'Hare Intl to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima2 stops$490
Bogotá
Bogotá1 stop$298
Medellín
Medellín1 stop$309
Sao Paulo
Sao Paulo2 stops$631
Rio de Janeiro
Rio de Janeiro1 stop$587
Santiago
Santiago2 stops$637
Cartagena
Cartagena1 stop$303
Quito
Quito1 stop$425
Guayaquil
Guayaquil1 stop$322
Cali
Cali1 stop$359
Cusco
Cusco3 stops$684
Georgetown
Georgetown1 stop$436
Pereira
Pereira1 stop$457
Barranquilla
Barranquilla1 stop$299
Montevideo
Montevideo2 stops$868
Santa Marta
Santa Marta1 stop$443
Asuncion
Asuncion1 stop$857
Lima
Lima2 stops$490
Bogotá
Bogotá1 stop$298
Medellín
Medellín1 stop$309
Sao Paulo
Sao Paulo2 stops$631
Rio de Janeiro
Rio de Janeiro1 stop$587
Santiago
Santiago2 stops$637
Cartagena
Cartagena1 stop$303
Quito
Quito1 stop$425
Guayaquil
Guayaquil1 stop$322
Cali
Cali1 stop$359
Cusco
Cusco3 stops$684
Georgetown
Georgetown1 stop$436
Pereira
Pereira1 stop$457
Barranquilla
Barranquilla1 stop$299
Montevideo
Montevideo2 stops$868
Santa Marta
Santa Marta1 stop$443
Asuncion
Asuncion1 stop$857

Book Cheap O'Hare Intl to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from O'Hare Intl to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from O'Hare Intl to South America

Wed, Apr 22 - Sat, Apr 25
Spirit Airlines Logo
7:15 pm - 1:12 pm
ORD
-
BOG
17h 57m
1 stop
Spirit Airlines Logo
2:07 pm - 12:24 am
BOG
-
ORD
10h 17m
1 stop
$298Spirit Airlines
Mon, May 11 - Fri, May 15
Spirit Airlines Logo
5:05 am - 1:03 pm
ORD
-
BOG
7h 58m
1 stop
Spirit Airlines Logo
2:08 pm - 11:15 pm
BOG
-
ORD
9h 07m
1 stop
$302Spirit Airlines
Sun, Apr 19 - Wed, Apr 22
Spirit Airlines Logo
5:05 am - 12:06 pm
ORD
-
CTG
7h 01m
1 stop
Spirit Airlines Logo
1:11 pm - 6:20 pm
CTG
-
ORD
29h 09m
2 stops
$303Spirit Airlines
Thu, Apr 23 - Thu, Apr 30
Spirit Airlines Logo
5:05 am - 12:06 pm
ORD
-
CTG
7h 01m
1 stop
Spirit Airlines Logo
1:11 pm - 12:24 am
CTG
-
ORD
11h 13m
1 stop
$304Spirit Airlines
Sun, Apr 19 - Wed, Apr 22
Copa Airlines Logo
3:05 pm - 12:06 am
ORD
-
BOG
9h 01m
1 stop
Copa Airlines Logo
2:24 pm - 1:13 am
BOG
-
ORD
10h 49m
1 stop
$305Copa Airlines
Mon, Apr 20 - Wed, May 6
United Airlines Logo
5:15 pm - 4:54 am
ORD
-
BOG
11h 39m
1 stop
United Airlines Logo
8:30 am - 11:15 pm
BOG
-
ORD
14h 45m
1 stop
$314United Airlines
Mon, Apr 13 - Sun, Apr 19
Avianca Logo
11:20 pm - 1:05 pm
ORD
-
UIO
13h 45m
1 stop
Avianca Logo
3:30 am - 9:20 pm
UIO
-
ORD
17h 50m
1 stop
$428Avianca
Thu, May 7 - Tue, May 12
Avianca Logo
11:20 pm - 1:05 pm
ORD
-
UIO
13h 45m
1 stop
Avianca Logo
10:10 am - 9:20 pm
UIO
-
ORD
11h 10m
1 stop
$430Avianca
Wed, Sep 23 - Wed, Sep 30
American Airlines Logo
2:50 pm - 10:25 am
ORD
-
GIG
17h 35m
2 stops
American Airlines Logo
2:50 pm - 8:45 am
GIG
-
ORD
19h 55m
2 stops
$616American Airlines
Thu, May 14 - Mon, Jun 15
United Airlines Logo
12:55 pm - 4:45 pm
ORD
-
SDU
25h 50m
2 stops
United Airlines Logo
1:45 pm - 6:45 am
SDU
-
ORD
19h 00m
1 stop
$791United Airlines
Booking Insights

KAYAK's insights & trends for O'Hare Intl to South America flights

Get data-powered insights and trends into flights from O'Hare Intl to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest Chicago O'Hare Intl Airport to South America flight route?

Data is based on round-trip flight searches on KAYAK over the past month.

The cheapest ticket to South America from Chicago O'Hare Intl Airport found in the last 72 hours was to Bogotá, at $310 round-trip. The most popular route is from Chicago O'Hare Intl Airport (ORD) to Bogotá (BOG), and the cheapest round-trip airline ticket found on this route in the last 72 hours was $310.

Can I save money by flying with a layover from Chicago O'Hare Intl Airport to South America?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $597, prices are generally cheapest when you fly direct.

What is the cheapest month to fly from Chicago O'Hare Intl Airport to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Chicago O'Hare Intl Airport to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Chicago O'Hare Intl Airport to South America is February, when tickets cost $563 (return) on average. On the other hand, the most expensive months are December and August, when the average cost of round-trip tickets is $773 and $654 respectively.

How far in advance should I book a flight from Chicago O'Hare Intl Airport to South America?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Chicago O'Hare Intl Airport to South America, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Chicago O'Hare Intl Airport to South America, you should book around 2 weeks before departure, which saves you about 12% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 4 weeks before departure.

Good to know

Low seasonOctober
Cheapest flight$84
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 29% increase in price.
Flight from Chicago O'Hare Airport to Medellín Jose Maria Cordova Intl

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Chicago O'Hare Airport to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Chicago O'Hare Airport to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Chicago O'Hare Airport to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Chicago O'Hare Airport to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Chicago O'Hare Airport to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Chicago O'Hare Airport to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Chicago O'Hare Airport to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Chicago O'Hare Airport to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 5 airlines serving from O'Hare Intl to South America

 
Need help choosing which airline to fly with from O'Hare Intl to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1575 reviews
6.8Entertainment
7.4Comfort
8.1Crew
7.7Boarding
6.8Food
Airline reviews

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

8.0 ExcellentLuis, Mar 2026
LIM - PTY
Read more Copa Airlines reviews

Boarding was confusing from staff telling going to preboard and than to group 1 Airplane was not cooling at the beginning

Do not book it’s a scam! They stole $1200 from me

Seats were awful. Media should have been included for such a long flight.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Very strict carry on rules meant most of the plane had to gate check their luggage. As is often the case had things that were broken because of this, but I appreciated not being charged to gate check. Otherwise good flight and great crew once on the plane

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

I liked the meatloaf the chicken was awful but the plane was on time and got there and the staff was nice.

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

Honestly first time flying with delta and it was pretty good. All the process very smooth and crew was always nice and attentive.

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

Deleted flight made me loose my connection flight now stuck in Atlanta for a day

Apart of Sky miles delta. And they go everywhere in Brazil

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

I booked a flight through Kayak to Brazil I have traveled to Brazil several times before Kayak Delta or LATAM never mentioned during the booking or in the pre flight process that the visa requirements to visit Brazil have changed earlier this year. I was unaware of this change and as such never got a visa and was unable to fly from JFK to Sao Paulo Add to this that Delta allowed me to fly from Boston to JFK which they should not have as I didn’t have a visa. It has been a terrible experience and a huge loss of money

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

The plane broke down at the Lima stopover and they offered to put me on a flight the be t day but I had to be back in LA that morning and so I had to buy another ticket from Avianca and United for $2k I asked LATAM for compensation and received none. Very bad experience

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

Great until we got to FRA. The next trip leg we were put in Business Class where seats had minimal padding!!!! They were awful and United Airlines needs to have their Lufthansa partner up their game or I won’t fly with them again!!

No meal service to the back of the plane as it started late or was too slow to get it out before it was time to land.

Terrible, if possible won't be flying again anytime soon!

Efficient boarding and early departure. Very smooth flight. Early arrival in ATL. Great flight.

Smooth and easy boarding, comfortable for the entire 5 hour flight, and the seat back entertainment was great! I appreciated all the features, from location info and maps, movies, the ability to connect with Bluetooth headphones, and good selection of movies. Food was good, normal airline snacks (I didn’t purchase anything)

Awful. No counter attendants. No dinner offered due to delays.

This trip did not start off well. The inbound flight was delayed about 20 minutes. Then, after initial onboarding, the passengers had to deplane due to a mechanical problem. That took about 30 minutes to fix and be cleared. Then, reboarding was chaotic. It took a long time to sort passengers and two passengers on standby were ticketed but there was no seat. So, they had to deplane. One of the flight crew was trying to help passengers figure out a place to put their carry-on bags and that took more time. In the end, our scheduled 10:30 am departure did not actually take off until about 12:05 pm CST. The flight itself was long but we got to Houston. Some passengers missed their connecting flights and had to rebook. Not the best of flights I've had.

We were delayed for about an hour from taking off due to traffic control procedures at the destination airport. But once in the air, the flight went well. The crew members were great and provided cabin service despite moderate turbulence during much of the flight.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Not being stranded in Chicago for her airport to 11:30 tomorrow morning the 3rd

Delays experienced in boarding/take off due to incoming plane delayed. However, the boarding time/depart time in the app was significantly delayed in providing these updates. Usually not updated until an hour after we should have already boarded. Poorly managed.

Moved to earlier flight which unexpectedly had maintenance issues initially indicated as quick fix to ultimately plane changes. Moved back to original flight, also delayed. In all cases customer updates and communication very unclear, no updates on drivers for delays.

Typical AA - late by 90+ mn. Gate changed twice... Changed the departure time 6 times No explanation, no communication on reasons for delay I travel with AA twice a year... and it is consistently very poor.. I will continue to use AA only when i have to.

The gate got changed several times and the flight was delayed over an hour. Awful experience

American continues to decline in their customer service and its beyond disappointing.

It was an older plane. First Class was not especially roomy or comfortable. It was a short flight so there were no meal but they did offer mixed nuts which used to be normal but now is rare. Crew member was very polite and professional.

Flight to Tampa was delayed taking off due to plane arriving late but no other issues

As previously stated the delay I experienced flying from Wichita to Chicago caused a host of issues. When I finally was able to be booked on the last remaining American flight from Chicago to Cincinnati, the gate changed four times with the last change occurring very near the scheduled boarding time. While I didn't have a problem moving from gate to gate, I did notice and make note of others that had mobility issues and had to move each time for the gate change.

Maintenance took a very long time and then we were in a holding pattern. While a one-off maintenance issue is standard, there were delays on both of my flights for this trip based on maintenance issues with the planes, which delayed both flights over 45 minutes. Thankfully, I didn't have any connections but it wasn't an experience that would make me pick AA if I have other options.

No Snacks or Entertainment. The flight was short, snacks should still be given.

The worst experience I've ever had because the "people" @ Avianca wouldn't let me fly because they said I needed a round trip ticket

Seating was tight. Seats don't recline. Initial flight was cancelled. Lost two days of vacation.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

only a bag of chips and a bottle of water in business class was served

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Staff are the rudest in the industry … awful customer service … will never fly Avianca again

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Everything you need to know for your flight to South America

Information on your arrival and departure airports