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Find cheap flights from Iowa to San Diego from $76

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to San Diego departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Tue 6/4
Tue 6/11

Search hundreds of travel sites at once for deals on flights to San Diego

In the last 7 days travelers have searched 42,830,901 times on KAYAK, and here is why:

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Good to know

Low season

January

High season

July

Cheapest flight

$76
Best time to beat the crowds with an average 12% drop in price.
Most popular time to fly with an average 11% increase in price.
Flight from Des Moines to San Diego

FAQs for booking flights from Iowa to San Diego

  • How does KAYAK find such low prices on flights from Iowa to San Diego?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Iowa to San Diego.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Iowa to San Diego?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to San Diego from Iowa is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Iowa to San Diego?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to San Diego with an airline and back to Iowa with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Iowa to San Diego?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to San Diego from Iowa up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from Iowa to San Diego?

Find which airlines fly direct from Iowa to San Diego, which days they fly and book direct flights.

Nonstop departures

Iowa to San Diego

Monday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Tuesday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Wednesday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Thursday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Friday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Saturday

ANA, Aer Lingus, Aeromexico, +56 more

ANA, Aer Lingus, +57 more

Sunday

ANA, Aer Lingus, Aeromexico, +56 more

ANA, Aer Lingus, +57 more

See more direct flights

Nonstop returns

San Diego to Iowa

Monday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Tuesday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Wednesday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Thursday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Friday

ANA, Aer Lingus, Aeromexico, +57 more

ANA, Aer Lingus, +58 more

Saturday

ANA, Aer Lingus, Aeromexico, +56 more

ANA, Aer Lingus, +57 more

Sunday

ANA, Aer Lingus, Aeromexico, +56 more

ANA, Aer Lingus, +57 more

See more direct flights
See more direct flights

Book cheap flights from Iowa to San Diego

Recent round-trip flight deals

5/20Mon
1 stopFrontier
17h 57mDSM-SAN
6/1Sat
1 stopFrontier
10h 44mSAN-DSM
$154
6/3Mon
nonstopAllegiant Air
3h 45mDSM-SAN
6/7Fri
nonstopAllegiant Air
3h 25mSAN-DSM
$159
6/3Mon
1 stop
17h 57mDSM-SAN
6/7Fri
nonstop
3h 25mSAN-DSM
$201
5/31Fri
1 stop
11h 40mDSM-SAN
6/7Fri
nonstop
3h 25mSAN-DSM
$215
5/21Tue
1 stopUnited Airlines
6h 36mCID-SAN
5/25Sat
1 stopUnited Airlines
7h 27mSAN-CID
$286
5/30Thu
1 stopAmerican Airlines
8h 33mDSM-SAN
6/4Tue
1 stopAmerican Airlines
5h 22mSAN-DSM
$302
6/4Tue
1 stopAmerican Airlines
6h 15mDSM-SAN
6/11Tue
1 stopAmerican Airlines
5h 39mSAN-DSM
$304
5/21Tue
1 stopDelta
8h 44mCID-SAN
5/25Sat
1 stopDelta
7h 32mSAN-CID
$312
10/28Mon
1 stopDelta
9h 35mDSM-SAN
10/31Thu
1 stopDelta
7h 45mSAN-DSM
$344
8/15Thu
2 stopsUnited Airlines
10h 29mDSM-SAN
8/18Sun
1 stopUnited Airlines
6h 24mSAN-DSM
$450

Search by stops

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Recent one-way flight deals

5/25Sat
1 stopFrontier
11h 16mDSM-SAN
$76
6/3Mon
nonstopAllegiant Air
3h 45mDSM-SAN
$85
5/20Mon
1 stopFrontier
11h 32mDSM-SAN
$91
6/3Mon
2 stops
25h 23mDSM-SAN
$121
6/3Mon
3 stops
39h 03mDSM-SAN
$128
6/4Tue
1 stopAmerican Airlines
7h 47mCID-SAN
$133
6/18Tue
1 stopAmerican Airlines
8h 40mDSM-SAN
$151
6/4Tue
2 stopsDelta
11h 06mCID-SAN
$224
6/2Sun
2 stopsUnited Airlines
21h 08mCID-SAN
$344
6/4Tue
3 stopsUnited Airlines
17h 44mCID-SAN
$373

Search by stops

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Search by price

Last minute flights from Iowa to San Diego

Last minute flight, train and bus deals

5/10Fri
multi-stopFrontier
22h 02mDSM-SAN
5/18Sat
multi-stopFrontier
10h 29mSAN-DSM
$270
5/10Fri
multi-stopFrontier
21h 37mCID-SAN
5/18Sat
multi-stopFrontier
27h 48mSAN-CID
$270
5/9Thu
multi-stop
10h 37mDSM-SAN
6/2Sun
multi-stop
13h 58mSAN-DSM
$366
5/6Mon
multi-stopUnited Airlines
6h 55mCID-SAN
5/13Mon
multi-stopUnited Airlines
5h 14mSAN-CID
$413
5/9Thu
multi-stop
7h 06mDSM-SAN
6/2Sun
multi-stop
20h 57mSAN-DSM
$416
5/6Mon
multi-stopDelta
9h 49mCID-SAN
5/13Mon
multi-stopDelta
8h 52mSAN-CID
$418
5/10Fri
multi-stopAmerican Airlines
8h 19mCID-SAN
5/18Sat
multi-stopAmerican Airlines
8h 09mSAN-CID
$473
5/6Mon
multi-stopDelta
9h 49mCID-SAN
5/13Mon
multi-stopDelta
13h 03mSAN-CID
$576
5/6Mon
multi-stopAmerican Airlines
8h 33mDSM-SAN
5/18Sat
multi-stopAmerican Airlines
8h 17mSAN-DSM
$581
5/6Mon
multi-stopUnited Airlines
9h 01mDSM-SAN
5/8Wed
multi-stopUnited Airlines
7h 14mSAN-DSM
$669

Search by stops

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Flights to San Diego

Destination:

San Diego (SAN)United States

Return flight deals:

San Diego - Iowa

Cabin classes:

$164