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Find cheap flights from Missouri to Panama from $450

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Missouri to Panama departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Wed 5/29
Wed 6/5

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In the last 7 days travelers have searched 43,219,010 times on KAYAK, and here is why:

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Good to know

Low season

October

High season

March

Cheapest flight

$450
Best time to beat the crowds with an average 9% drop in price.
Most popular time to fly and prices are also 11% lower on average.
Flight from St. Louis to Panama City

FAQs for booking flights from Missouri to Panama

  • How does KAYAK find such low prices on flights from Missouri to Panama?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Missouri to Panama.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Missouri to Panama?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama from Missouri is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Missouri to Panama?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama with an airline and back to Missouri with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Missouri to Panama?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama from Missouri up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Book cheap flights from Missouri to Panama

Recent round-trip flight deals

9/25Wed
1 stopDelta
6h 55mSTL-PTY
10/9Wed
1 stopDelta
9h 15mPTY-STL
$450
9/24Tue
2 stopsAmerican Airlines
21h 55mSTL-PTY
10/8Tue
2 stopsAmerican Airlines
20h 09mPTY-STL
$451
9/3Tue
2 stopsAmerican Airlines
8h 44mSTL-PTY
9/30Mon
2 stopsAmerican Airlines
24h 13mPTY-STL
$453
9/25Wed
1 stopUnited Airlines
8h 04mSTL-PTY
10/7Mon
2 stopsUnited Airlines
18h 27mPTY-STL
$454
9/22Sun
1 stopDelta
6h 55mSTL-PTY
10/8Tue
1 stopDelta
9h 15mPTY-STL
$470
9/26Thu
2 stopsAmerican Airlines
17h 35mSTL-PTY
10/10Thu
2 stopsAmerican Airlines
20h 09mPTY-STL
$471
9/4Wed
2 stopsAmerican Airlines
21h 55mSTL-PTY
9/8Sun
2 stopsAmerican Airlines
19h 19mPTY-STL
$473
8/30Fri
2 stopsAmerican Airlines
21h 52mSTL-PTY
9/4Wed
2 stopsAmerican Airlines
19h 19mPTY-STL
$474
6/22Sat
1 stopUnited Airlines
11h 59mSGF-PTY
6/28Fri
1 stopUnited Airlines
24h 25mPTY-SGF
$480
10/9Wed
1 stopUnited Airlines
10h 07mMCI-PTY
10/15Tue
1 stopUnited Airlines
18h 06mPTY-MCI
$486

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Last minute flights from Missouri to Panama

Last minute flight, train and bus deals

4/30Tue
multi-stopDelta
6h 47mSTL-PTY
5/8Wed
multi-stopDelta
9h 27mPTY-STL
$490
4/30Tue
multi-stopAmerican Airlines
19h 35mSTL-PTY
5/8Wed
multi-stopAmerican Airlines
20h 28mPTY-STL
$493
5/2Thu
multi-stopUnited Airlines
8h 04mMCI-PTY
5/9Thu
multi-stopUnited Airlines
8h 48mPTY-MCI
$526
5/2Thu
multi-stopAmerican Airlines
7h 50mMCI-PTY
5/9Thu
multi-stopAmerican Airlines
20h 32mPTY-MCI
$529
5/2Thu
multi-stopUnited Airlines
13h 31mMCI-PTY
5/9Thu
multi-stopUnited Airlines
22h 07mPTY-MCI
$530
5/2Thu
multi-stop
15h 18mMCI-PTY
5/9Thu
multi-stop
24h 21mPTY-MCI
$764
5/2Thu
multi-stop
15h 18mMCI-PTY
5/9Thu
multi-stop
24h 21mPTY-MCI
$882

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Flights to Panama

Return flight deals:

Panama - Missouri

Cabin classes: