SCL - MDE

$162 Find Cheap Flights from Santiago to Medellín - Compare and Save

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to Medellín departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Medellín Jose Maria Cordova Intl Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Medellín, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Medellín, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$323
Typical prices: $457-$336
JetSMART
Mon 6/29Sun 7/5
SCL - MDE • 1 stop
Cheapest non-stop
$346
Typical prices: $372-$234
JetSMART
Mon 8/24Sun 8/30
SCL - MDE • Non-stop
Nonstop flights
Mon, Tue, Fri, Sat
You can fly direct with JetSMART. Average duration is 6h 24m
Direct flights
Direct flights
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Direct flights
Direct flights
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Top layover airports
Cheapest • Avg $378 (round-trip)
Shortest trip • 9h 22m (one-way)
Insights
Insights
Insights
Insights
Avoid delays
Most punctual • 76% on-time
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 12 weeks in advance save around 27% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
Cheapest • 14% price drop
Most popular
Good to know
Good to know
+1
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Good to know
Good to know
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Medellín!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Santiago to Medellín (SCL-MDE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to Medellín that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to Medellín

Mon, Jun 29 - Sun, Jul 5
JetSMART Logo
3:30 pm - 12:13 am
SCL
-
MDE
9h 43m
1 stop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$323JetSMART
Wed, Aug 26 - Sun, Sep 6
JetSMART Logo
3:30 pm - 7:54 pm
SCL
-
MDE
29h 24m
1 stop
JetSMART Logo
5:01 pm - 1:11 am
MDE
-
SCL
6h 10mnonstop
$324JetSMART
Sun, Jul 19 - Sun, Aug 23
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:00 am - 4:17 am
MDE
-
SCL
22h 17m
1 stop
$326JetSMART
Wed, Aug 12 - Wed, Aug 19
JetSMART Logo
3:30 pm - 2:25 pm
SCL
-
MDE
23h 55m
1 stop
JetSMART Logo
6:39 am - 4:17 am
MDE
-
SCL
20h 38m
1 stop
$328JetSMART
Sun, Sep 13 - Fri, Sep 18
JetSMART Logo
4:30 pm - 4:54 pm
SCL
-
MDE
26h 24m
1 stop
JetSMART Logo
5:10 am - 5:17 am
MDE
-
SCL
22h 07m
1 stop
$332JetSMART
Mon, Aug 24 - Thu, Aug 27
JetSMART Logo
3:30 pm - 1:14 pm
SCL
-
MDE
22h 44m
1 stop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$333JetSMART
Mon, Aug 31 - Mon, Sep 7
JetSMART Logo
3:30 pm - 12:13 am
SCL
-
MDE
9h 43m
1 stop
JetSMART Logo
5:01 pm - 1:11 am
MDE
-
SCL
6h 10mnonstop
$337JetSMART
Sun, Aug 16 - Mon, Aug 31
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
6:26 am - 4:17 am
MDE
-
SCL
20h 51m
1 stop
$338JetSMART
Mon, Aug 31 - Thu, Sep 24
JetSMART Logo
3:30 pm - 12:13 am
SCL
-
MDE
9h 43m
1 stop
JetSMART Logo
8:30 pm - 5:17 am
MDE
-
SCL
30h 47m
1 stop
$340JetSMART
Wed, Jul 1 - Sun, Jul 5
JetSMART Logo
4:41 am - 9:45 am
SCL
-
MDE
30h 04m
1 stop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$342JetSMART
Booking Insights

KAYAK's insights & trends for Santiago to Medellín flights

Get data-powered insights and trends into flights from Santiago to Medellín to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santiago to Medellín Jose Maria Cordova Intl Airport?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santiago to Medellín Jose Maria Cordova Intl Airport departing in June.

What’s the cheapest day of the week to fly from Santiago to Medellín?

The average price of all round-trip flights from Santiago to Medellín Jose Maria Cordova Intl Airport clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Medellín on a Saturday and more expensive on a Sunday. On your return trip to Santiago, you should consider flying back on a Wednesday, and avoid Thursdays for better deals.

What is the cheapest month to fly from Santiago to Medellín Jose Maria Cordova Intl Airport?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to Medellín Jose Maria Cordova Intl Airport, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to Medellín Jose Maria Cordova Intl Airport is March, where tickets cost $319 (return) on average. On the other hand, the most expensive months are January and June, where the average cost of round-trip tickets is $413 and $404 respectively.

Can I save money by flying with a layover from Santiago to Medellín Jose Maria Cordova Intl Airport?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $314 on average.

How far in advance should I book a flight from Santiago to Medellín Jose Maria Cordova Intl Airport?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to Medellín Jose Maria Cordova Intl Airport, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to Medellín Jose Maria Cordova Intl Airport, you should book around 12 weeks before departure, which saves you about 27% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 23 weeks before departure.

Expert advice

Expert advice for your flight from Santiago to Medellín

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Mark Chesnut

Mark Chesnut

Expert on Avianca

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Daniel Scheffler

Daniel Scheffler

Expert on JetSMART

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Good to know

Low seasonMay
Cheapest flight$162
Best time to beat the crowds with an average 8% drop in price.
Most popular time to fly with an average 6% increase in price.
Flight from Santiago to Medellín

When to book flights from Santiago to Medellín

Are your dates flexible? Find out the best times to travel from Santiago to Medellín based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Santiago to Medellín flights

  • What is the cheapest flight from Santiago to Medellín Jose Maria Cordova Intl Airport?

    In the last 5 days, the lowest price for a flight from Santiago to Medellín Jose Maria Cordova Intl Airport was $162 for a one-way ticket and $323 for a round-trip.

  • Do I need a passport to fly between Santiago and Medellín?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santiago and on arrival in Medellín.

  • Which airports will I be using when flying from Santiago to Medellín?

    Santiago airport is called Santiago Arturo Merino Benitez and the only airport in Medellín is Medellín Jose Maria Cordova Intl.

  • Which aircraft models fly most regularly from Santiago to Medellín?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Santiago to Medellín flight route.

  • On which days can I fly direct from Santiago to Medellín?

    You can catch a nonstop flight from Santiago to Medellín on Monday, Tuesday, Friday, and Saturday.

  • Which is the best airline for flights from Santiago to Medellín, LATAM Airlines or JetSMART?

    The two airlines most popular with KAYAK users for flights from Santiago to Medellín are LATAM Airlines and JetSMART. With an average price for the route of $397 and an overall rating of 7.4, LATAM Airlines is the most popular choice. JetSMART is also a great choice for the route, with an average price of $383 and an overall rating of 6.8.

  • How does KAYAK find such low prices on flights from Santiago to Medellín?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to Medellín.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to Medellín?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Medellín from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to Medellín?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Medellín with an airline and back to Santiago with another airline. Booking your flights between Santiago and MDE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to Medellín?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Medellín from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santiago to Medellín Jose Maria Cordova Intl Airport

  • Looking for a cheap flight? 25% of our users found flights on this route for $227 or less one-way.

Prefer to fly direct from Santiago to Medellín?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl.
Find which airlines fly direct from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport, which days they fly and book direct flights.

Direct departures

Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl

Monday

JetSMART

JetSMART

Tuesday

JetSMART

JetSMART

Friday

JetSMART

JetSMART

Saturday

JetSMART

JetSMART

See more direct flights

Direct returns

Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez

Monday

JetSMART

JetSMART

Thursday

JetSMART

JetSMART

Friday

JetSMART

JetSMART

Sunday

JetSMART

JetSMART

See more direct flights

Reviews of the top airlines flying from Santiago to Medellín

 
See real verified KAYAK customer reviews for airlines flying from Santiago to Medellín. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to Medellín? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
LATAM AirlinesOverall score based on 1933 reviews
8.0Crew
7.3Comfort
7.5Boarding
7.0Entertainment
6.7Food
Airline reviews

We liked the way we were treated by the sraff at lima airport counter and the the flight attendants. We did not like the fact that the kiosks at airport rebooted after we entered our information and then told us that there was an issueand we needed to go to the counter. Such a waste of time for a group of 6. Once we got our boarding passes there was no assigned gate so we did not know where to go.

8.0 ExcellentAnonymous, Apr 2026
LIM - JFK
Read more LATAM Airlines reviews

We liked the way we were treated by the sraff at lima airport counter and the the flight attendants. We did not like the fact that the kiosks at airport rebooted after we entered our information and then told us that there was an issueand we needed to go to the counter. Such a waste of time for a group of 6. Once we got our boarding passes there was no assigned gate so we did not know where to go.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

LATAM is a great airline who takes care of there guests. They consistently walk around and see if you need water in addition to taking care of all the passengers. The chicken in process is really easy and I’m always offered a chance for an upgrade which I appreciate.

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

Good flight, boarding ok and crew very nice. Flight was not full so I was able to be very comfortable. Blanket and pillow provided with was good as it was very cold during the flight . Food was very good(small snack sandwich and an excellent piece of orange cake). Overall good flight, no complaints.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

First of all, could be Kyak's fault he we couldn't for days check in on line via Kayak or Jet Smart. We can't get the app either. Luckily on LATAM I managed to get the WiFi and contact Jet smart via what's app. This was horrendous and the person was unhelpful to start with. But we explained and she managed to check us in as if she didn't we wouldn't have got on the flight as would've been too late to check in. At the gate they were checking everyone's bag for size. My bag was 1 cm over and they tried to charge me $255 soles to carry it on but was 225 to put it in the hold. We had to pay to put both bags in the hold adding £100 to the cost of the flight. We had to carry the bags as the jet smart sight doesn't allow us to add bags which would've cost us £13 each so £26 on booking instead of £100. Staff at the gate were rude to us and other passengers. I'm sure they were on commission to get money off passengers for the bags. The lady flight attendant was pleasant but over ruled buy this jumped up young guy when I asked if my partner could sit beside me. The plane was 1/3 full. Then he was rude most of the flight. Avoid jet smart at all costs! Worrying thing is we have a return journey with these shower of.... We have been on their site the past two days trying to add bags but site won't do anything. I think this is on purpose to get more money out of passengers. As I said avoid at all costs.

Terrible website. Does not work most of the time I tired using it to check in. Had to have someone from another country help me check in. Their customer service is the worst.

The crew was polite, the Captain specially was cool! But the onboard service was nonexistent: No entertainment, no food, no reclining seats. I know it is a low cost, but the cost of the ticket was not so low for just the transport service.

Was a good flight, no delays and good customer service.

Customer service is horrible. Our flight was at 9pm and we were at check in counter by 7pm. The crew strolls in at 7.30 without even an apology. We were suppose to get our boarding passes online but the website was not working at expected and the staff kept arguing with us saying that is not possible.

There was no entertainment but everyone just used their phones.

The app told us that carry on luggage was included but we were made to pay for it again at the check in counter, making it a very expensive flight. Not happy

I was charged 168 soles for kids stroller. We have travelled across the world and have never charged for the stroller. Horrific airlines and the staff was extremely rude. They wouldn’t let us board unless we pay the extra baggage cost. Never ever flying this airline and I would recommend the same for the others.

Avoid this airline. They are unprofessional. The captain left several passengers on ground due to covid restrictions which were never communicated. As a chilean, I am ashamed that this low level airline comes from my country. Remember this horrible brand and avoid it... Jetsmart

Everything you need to know for your flight from Santiago to Medellín

Information on your arrival and departure airports