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MDE - SCL

Find cheap flights from Medellín to Santiago from $176

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to Santiago departing on 8/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Mon 6/3
Mon 6/10

Search hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Santiago, as well as popular online travel agencies
In the last 7 days travelers have searched 43,369,418 times on KAYAK, and here is why:

Save 22% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Filter your dealsChoose cabin class, free Wi-Fi and more.

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Cheap flight deals from Medellín to Santiago (MDE-SCL)

Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
12:24 pm - 11:18 pmMDE-SCL
9h 54m1 stop
2:20 am - 10:56 amSCL-MDE
9h 36m1 stop
$281Copa Airlines
Find Deal
Wed, May 22 - Sun, May 26
8:33 am - 9:15 pmMDE-SCL
11h 42m2 stops
5:30 am - 4:05 pmSCL-MDE
11h 35m1 stop
$285LATAM Airlines
Find Deal
Wed, May 22 - Mon, May 27
7:33 am - 9:15 pmMDE-SCL
12h 42m2 stops
5:30 am - 4:05 pmSCL-MDE
11h 35m1 stop
$286LATAM Airlines
Find Deal
Wed, May 22 - Mon, May 27
2:13 pm - 9:21 pmMDE-SCL
6h 08mnonstop
7:49 am - 1:13 pmSCL-MDE
6h 24mnonstop
$290JetSMART
Find Deal
Fri, May 31 - Fri, Jun 7
7:00 am - 9:15 pmMDE-SCL
13h 15m2 stops
7:55 pm - 7:59 amSCL-MDE
13h 04m2 stops
$291LATAM Airlines
Find Deal
Wed, May 22 - Mon, May 27
2:13 pm - 9:21 pmMDE-SCL
6h 08mnonstop
7:55 pm - 5:26 pmSCL-MDE
22h 31m2 stops
Fri, May 31 - Fri, Jun 7
2:13 pm - 9:21 pmMDE-SCL
6h 08mnonstop
5:30 am - 6:59 amSCL-MDE
26h 29m3 stops
Fri, May 31 - Fri, Jun 7
2:13 pm - 9:21 pmMDE-SCL
6h 08mnonstop
10:36 am - 6:40 pmSCL-MDE
9h 04m1 stop
$314JetSMART
Find Deal
Wed, May 29 - Sat, Jun 1
4:16 am - 1:25 pmMDE-SCL
8h 09m1 stop
2:30 pm - 9:49 pmSCL-MDE
8h 19m1 stop
$317Avianca
Find Deal
Fri, Jun 14 - Sun, Jul 7
4:30 pm - 4:10 amMDE-SCL
10h 40m2 stops
2:30 pm - 11:01 pmSCL-MDE
9h 31m1 stop
$378Avianca
Find Deal
Fri, Jun 14 - Sun, Jul 7

Flights from Medellín to Santiago - Travel Insights & Trends

Get data-powered insights and trends into flights from Medellín to Santiago to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Medellín to Santiago?

The average price of all flights from Medellín Jose Maria Cordova Intl Airport to Santiago clicked on KAYAK for each day over the last 12 months.
For Medellín to Santiago, Wednesday is the cheapest day to fly on average and Thursday is the most expensive. Flying from Santiago back to Medellín, the best deals are generally found on Sunday, with Friday being the most expensive.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights from Medellín Jose Maria Cordova Intl Airport to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to Santiago is December, where tickets cost $413 on average. On the other hand, the most expensive months are July and March, where the average cost of tickets is $482 and $466 respectively.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

To calculate daily average prices, KAYAK takes all prices for each day before departure over the last year for flights from Medellín Jose Maria Cordova Intl Airport to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each month.
To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to Santiago, you should book around 5 days before departure. For the absolute cheapest price, our data suggests you should book 75 days before departure.

Which airlines provide the cheapest flights from Medellín to Santiago?

The cheapest price for the route for each airline clicked by KAYAK users in the last 72 hours.
The best deals for a one-way ticket found by KAYAK users over the last 3 days were on LATAM Airlines ($176) and Copa Airlines ($177). The cheapest round-trip tickets were found on Copa Airlines ($281) and LATAM Airlines ($285).

Which airlines fly non-stop between Medellín Jose Maria Cordova Intl Airport and Santiago?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for flights from Medellín Jose Maria Cordova Intl Airport to Santiago.
There are 2 airlines that fly nonstop from Medellín Jose Maria Cordova Intl Airport to Santiago. They are Avianca and JetSMART. The cheapest airline for this route is JetSMART, with the best one-way deal found costing $243. On average, the best prices for this route can be found at JetSMART.

How many flights are there between Medellín Jose Maria Cordova Intl Airport and Santiago per day?

Each day, there are 2 nonstop flights that take off from Medellín Jose Maria Cordova Intl Airport and land in Santiago, with an average flight time of 6h 04m. The most common departure time is 5:00 pm and most flights take off in the afternoon. Each week, there are 8 flights and there are the same amount of flights each day 2.

Which cabin class options are there for flights between Medellín Jose Maria Cordova Intl Airport and Santiago?

The average price of flights for each cabin class for the route found by users searching on KAYAK over the last 2 weeks.
There is only one cabin class option available for the route, which is Economy. Perform a search on KAYAK to find the latest prices and availability for all cabin fares, which differ across airlines.

How long does a flight from Medellín to Santiago take?

Direct flights cover the 2,748 miles separating Medellín to Santiago in about 6h 08m.

What’s the earliest departure time from Medellín to Santiago?

Early birds can take the earliest flight from Medellín Jose Maria Cordova Intl Airport at 2:13 pm and will be landing in Santiago at 9:21 pm.

What’s the latest departure time from Medellín to Santiago?

If you prefer to fly at night, the latest flight from Medellín Jose Maria Cordova Intl Airport to Santiago jets off at 5:45 pm and lands at 12:45 am.

Good to know

Low season

February

High season

December

Cheapest flight

$176
Best time to beat the crowds but there is an average 2% increase in price.
Most popular time to fly and prices are also 7% lower on average.
Flight from Medellín to Santiago

When to book flights from Medellín to Santiago

Are your dates flexible? Find out the best times to travel from Medellín to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to Santiago flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

    In the last 3 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to Santiago was $176 for a one-way ticket and $281 for a round-trip.

  • Do I need a passport to fly between Medellín and Santiago?

    A passport is required to fly from Medellín to Santiago.

  • Which aircraft models fly most regularly from Medellín to Santiago?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Medellín to Santiago flight route.

  • Which airline alliances offer flights from Medellín to Santiago?

    Star Alliance is the only airline alliance operating flights between Medellín and Santiago.

  • On which days can I fly direct from Medellín to Santiago?

    You can catch a nonstop flight from Medellín to Santiago on Monday, Wednesday, Friday, and Sunday.

  • Which is the best airline for flights from Medellín to Santiago, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Medellín to Santiago are Copa Airlines and LATAM Airlines. With an average price for the route of $667 and an overall rating of 7.8, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $458 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Medellín to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Medellín with another airline. Booking your flights between Medellín and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding a cheap flight from MDE to Santiago

  • Looking for a cheap flight? 25% of our users found flights on this route for $194 or less one-way and $316 or less round-trip.

Prefer to fly non-stop from Medellín to Santiago?

Find which airlines fly direct from Jose Maria Cordova Intl to Arturo Merino Benitez, which days they fly and book direct flights.

Nonstop departures

Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez

Monday

Avianca, JetSMART

Avianca, JetSMART

Wednesday

Avianca, JetSMART

Avianca, JetSMART

Friday

Avianca, JetSMART

Avianca, JetSMART

Sunday

Avianca, JetSMART

Avianca, JetSMART

See more direct flights

Nonstop returns

Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl

Monday

Avianca, JetSMART

Avianca, JetSMART

Tuesday

Avianca

Avianca

Wednesday

JetSMART

JetSMART

Thursday

Avianca

Avianca

Friday

JetSMART

JetSMART

Saturday

Avianca

Avianca

Sunday

JetSMART

JetSMART

See more direct flights
See more direct flights

Top 4 airlines serving from Medellín to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Medellín to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
Copa AirlinesOverall score based on 2806 reviews
8.3Crew
7.7Comfort
7.2Entertainment
7.3Food
8.1Boarding
Airline reviews

Very good, despite we had a delay because of some problems at the airport.

10.0 ExcellentAndres, Mar 2024CLO - PTY
Read more about Copa Airlines reviews

Very good, despite we had a delay because of some problems at the airport.

Copa me elige como "voluntario" para cambiarme y poder enviar a una familia a la cual había sobrevendido los tiquetes. Finalmente me envían a las carreras con Avianca, pero Copa lleva mis maletas hasta Panama y luego las devuelve a mi aeropuerto de origen, dejandome sin mis pertenencias y además no asumen la responsabilidad ya que dicen que es problema de Avianca Literalmente vi cuando el avión de Copa se lleva mis maletas, sus funcionarios en Bogota, incluyendo la gerente local me aseguran la entrega en Miami, pero simplemente era para poder engañarme y dar el cambio de silla por sobreventa

other than a slight delay in takeoff from Panama , the flights were excellent ..... we will continue to use Copa whenever possible for flights to and from Central and South America ....

Cons: "The turbulence was really bad ! I couldn’t sleep at all !"
Pros: "You are so good all the time."
Cons: "We understand that this time is tough because the Coronavirus, they took care of all of us, and also they were kind and friendly. Thank you so much, for everything"
Pros: "Crew and i ohhh ver all copa experience."
Cons: "Nothing. I am now a loyal Copa flier. Any of my trips to Latin America I will consider flying with Copa"
Pros: "Crew was great. Supportive and friendly. Plane was clean and comfortable."
Pros: "The seat comfort and staff especially the captain - very engaging"
Cons: "WiFi on the airplane to access flight map and other services."
Cons: "The amount of turbulence experienced was ridiculous. The landing was rough. This was the same for every flight with Copa on my round trip from SJO to MDE. This was extremely concerning."
Cons: "The seats are very uncomfortable but other than that it was wonderful!"

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

I didn't realize they didn't have bathrooms on the plane. Almost had a very bad situation.

It was confusing because I got a notification that my gate was changed when in reality it wasn’t

Everthing ok , crew very nice but but we had a bad experience with the wheel chair we had to wait too much for the chair, my husband couldn’t walk and he was in lot of pain , LATAM has to take care of that

It’s been some time since I saw the plane and the cabin that old and worn out.

I loved how polite the crew was even though some of them wasn't the best with English that they still done everything they could to help me with my needs food was amazing

Terrible They charged me 157$ for excess baggage even though my bags were within the normally accepted limits Flight was late. Service was poor. The snacks were really bad

It was a good experience, the flight was a little too long & the food was ok

Awful, horrible customer service. Flight got delayed and had to spend y the night in Bogota as a result. Very poor

Hostile flight attendants. Second flight with Jose so much better. Arrived 1/2 hour early. Thanks.

I expected the plane to be as the one I took from manaos to Bogota and unfortunately it wasn’t as nice, the sits didn’t recline and there was not onboard entertainment.

i was charged $140.00usd for my backpack the only luggage i had was my backpack

More than 3 hours of delay and not even a snack was given.

Seat space was terrible no food on a six hour flight

Boarding was very expedite. The chairs are fixed you can't rest comfortable during the flight.

No comfort at all. You should add at least 1 meal or a bottle of water. I wanted to buy one sandwich and everything was gone.

There was absolutely no food or drink service unless it was paid for. I am not used to this.

There was no bag included in the reservation. The price was double. Not properly advertised

The temperature was cold and the food that we had to pay for was awful. The crew didn’t even offer a free glass of water. It was a long, expensive and uncomfortable flight.

They could offer food and drink without having to pay extra for it,

The app told us that carry on luggage was included but we were made to pay for it again at the check in counter, making it a very expensive flight. Not happy

I was charged 168 soles for kids stroller. We have travelled across the world and have never charged for the stroller. Horrific airlines and the staff was extremely rude. They wouldn’t let us board unless we pay the extra baggage cost. Never ever flying this airline and I would recommend the same for the others.

Avoid this airline. They are unprofessional. The captain left several passengers on ground due to covid restrictions which were never communicated. As a chilean, I am ashamed that this low level airline comes from my country. Remember this horrible brand and avoid it... Jetsmart

Cons: "The plane was cramped. It was difficult to fit even small, personal items under the seat, especially if you want to put your feet there, too."
Pros: "They rescheduled the flight to 12 hours prior and I wasn’t notified and showed up at airport and didn’t have a flight got stuck kiwi said they wouldn’t help me were so mean had to buy new flight wasting thousands of dollars"
Cons: "Everything"
Cons: "Several safety issues onboard: luggage put in unsafe places, seatbelt sign missing during landing, restroom doors flapping open during flight. No free water. No towels or toilet paper."
Pros: "Worst experience and kayak take responsibility. Plane delayed 7 hours without message and with confusing timing. Was still showing plane flight 331 still at 3pm but delayed till 10pm. Showing. Arrival to still be 6pm. Then delayed again without any indication. Huge problem I lost a lot"
Cons: "Let us know when there is delay and be responsible"

Book cheap flights from Medellín to Santiago

Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Medellín to Santiago found on KAYAK in the last 72 hours.
8/27Tue
1 stopLATAM Airlines
10h 05mMDE-SCL
$176
5/23Thu
1 stopCopa Airlines
16h 26mMDE-SCL
$177
8/27Tue
2 stopsLATAM Airlines
14h 07mMDE-SCL
$181
6/10Mon
nonstopAvianca
6h 00mMDE-SCL
$192
5/24Fri
1 stopAvianca
8h 09mMDE-SCL
$194
8/27Tue
3 stopsLATAM Airlines
27h 14mMDE-SCL
$223
9/25Wed
1 stopCopa Airlines
15h 57mMDE-SCL
$225
5/23Thu
2 stopsAvianca
11h 31mMDE-SCL
$247
9/25Wed
2 stopsAvianca
11h 39mMDE-SCL
$301
5/24Fri
2 stopsAvianca
12h 59mMDE-SCL
$381

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Last minute flights from Medellín to Santiago

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Medellín to Santiago that are departing in the next 10 days.
5/6Mon
multi-stopCopa Airlines
9h 49mMDE-SCL
5/14Tue
multi-stopCopa Airlines
11h 00mSCL-MDE
$283
5/6Mon
multi-stopCopa Airlines
9h 49mMDE-SCL
5/13Mon
multi-stopCopa Airlines
9h 03mSCL-MDE
$327
5/9Thu
multi-stop
18h 02mMDE-SCL
5/12Sun
nonstop
6h 24mSCL-MDE
$329
5/6Mon
nonstopJetSMART
6h 08mMDE-SCL
5/13Mon
nonstopJetSMART
6h 24mSCL-MDE
$332
5/6Mon
multi-stop
9h 49mMDE-SCL
5/13Mon
nonstop
6h 24mSCL-MDE
$333
5/9Thu
multi-stopLATAM Airlines
18h 02mMDE-SCL
5/12Sun
multi-stopLATAM Airlines
14h 19mSCL-MDE
$336
5/9Thu
multi-stop
8h 42mMDE-SCL
5/12Sun
nonstop
6h 24mSCL-MDE
$341
5/9Thu
multi-stopLATAM Airlines
8h 42mMDE-SCL
5/12Sun
multi-stopLATAM Airlines
16h 14mSCL-MDE
$343
5/6Mon
multi-stopAvianca
10h 40mMDE-SCL
5/11Sat
multi-stopAvianca
9h 31mSCL-MDE
$872
5/6Mon
multi-stopAvianca
10h 40mMDE-SCL
5/11Sat
multi-stopAvianca
10h 03mSCL-MDE
$948

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Medellín - Santiago Flights

Departure:

Medellín (MDE)Colombia

Destination:

Santiago (SCL)Chile

Return flight deals:

Santiago - Medellín

Cabin classes:

$268

Browse origins:

  • Flights » 
  • Medellín Jose Maria Cordova Intl

Browse destinations:

  • Flights » 
  • Worldwide » 
  • Santiago