SCL - MDE

$177 Find Cheap Flights from Santiago to Medellín

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to Medellín departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult

KAYAK searches hundreds of travel sites at once for deals on flights to Medellín Jose Maria Cordova Intl Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Medellín, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Medellín, as well as popular online travel agencies
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Flights Deals

Cheap Flight Deals from Santiago to Medellín (SCL-MDE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to Medellín that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.

Recent round-trip flight deals from Santiago to Medellín

KAYAK's recommended round-trip deals from the most popular airlines that fly from Santiago to Medellín.
Discover the best prices for you by selecting your travel dates on KAYAK.
Copa Airlines Logo
12:13 am - 8:17 amSCL-MDE
9h 04m1 stop
Copa Airlines Logo
5:07 am - 7:24 pmMDE-SCL
13h 17m1 stop
$310Copa Airlines
Find Deal
Sun, Jun 1 - Wed, Jun 11
Copa Airlines Logo
4:11 am - 7:58 pmSCL-MDE
16h 47m1 stop
Copa Airlines Logo
5:07 am - 7:24 pmMDE-SCL
13h 17m1 stop
$336Copa Airlines
Find Deal
Sat, May 31 - Sat, Jun 7
JetSMART Logo
4:33 pm - 11:03 pmSCL-MDE
8h 30m1 stop
JetSMART Logo
5:54 pm - 4:51 amMDE-SCL
8h 57m1 stop
$343JetSMART
Find Deal
Wed, Oct 22 - Sun, Oct 26
JetSMART Logo
6:01 am - 5:05 pmSCL-MDE
13h 04m1 stop
JetSMART Logo
2:00 pm - 5:49 amMDE-SCL
13h 49m1 stop
$348JetSMART
Find Deal
Thu, Oct 23 - Mon, Oct 27
Avianca Logo
2:30 pm - 11:17 pmSCL-MDE
9h 47m1 stop
Avianca Logo
11:54 am - 10:30 pmMDE-SCL
9h 36m1 stop
$370Avianca
Find Deal
Tue, Jul 15 - Tue, Jul 22
Avianca Logo
5:55 am - 5:08 pmSCL-MDE
12h 13m2 stops
Avianca Logo
6:57 pm - 4:15 amMDE-SCL
8h 18m1 stop
$375Avianca
Find Deal
Wed, Jun 4 - Wed, Jun 11
LATAM Airlines Logo
7:20 am - 3:45 pmSCL-MDE
9h 25m1 stop
LATAM Airlines Logo
3:55 am - 5:35 pmMDE-SCL
12h 40m1 stop
$409LATAM Airlines
Find Deal
Mon, Jun 30 - Tue, Aug 5
 Logo
11:35 am - 10:35 pmSCL-MDE
13h 00m2 stops
 Logo
2:00 pm - 5:49 amMDE-SCL
13h 49m1 stop
Thu, Oct 23 - Mon, Oct 27
LATAM Airlines Logo
4:15 am - 2:56 pmSCL-MDE
11h 41m2 stops
LATAM Airlines Logo
6:20 pm - 3:30 amMDE-SCL
8h 10m1 stop
$414LATAM Airlines
Find Deal
Mon, Jun 30 - Wed, Aug 6
 Logo
12:35 am - 5:20 pmSCL-MDE
17h 45m2 stops
 Logo
5:30 am - 4:17 amMDE-SCL
21h 47m1 stop
Sun, Jun 15 - Mon, Jun 23
Expert advice

Expert advice for your flight from Santiago to Medellín

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
JetSMART

JetSMART offers low-cost fares with a small handbag included; extras cost more.


Print your boarding pass in advance to avoid airport fees.

Read more about JetSMARTby Daniel Scheffler
Avianca

Avianca's Classic fare includes a carry-on, personal item, and checked bag.


Avianca offers lounge access with Business fares, including showers and workspaces.

Our travel experts
Daniel Scheffler

Daniel Scheffler

Expert on JetSMART

Daniel Scheffler

Daniel Scheffler

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Read more
Mark Chesnut

Mark Chesnut

Expert on Avianca

Mark Chesnut

Mark Chesnut

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Read more
Useful Info

KAYAK's insights & trends for Santiago to Medellín flights

Get data-powered insights and trends into flights from Santiago to Medellín to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Santiago to Medellín?

The average price of all round-trip flights from Santiago to Medellín Jose Maria Cordova Intl Airport clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Medellín on a Sunday and more expensive on a Saturday. On your return trip to Santiago, you should consider flying back on a Tuesday, and avoid Sundays for better deals.

What is the cheapest month to fly from Santiago to Medellín Jose Maria Cordova Intl Airport?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to Medellín Jose Maria Cordova Intl Airport, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to Medellín Jose Maria Cordova Intl Airport is August, where tickets cost $288 (return) on average. On the other hand, the most expensive months are January and December, where the average cost of round-trip tickets is $403 and $383 respectively.

Can I save money by flying with a layover from Santiago to Medellín Jose Maria Cordova Intl Airport?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

Yes, flying with a layover may cost you more time, but you can also save money on the route, with a 1 stop layover the cheapest option at $458 on average.

How far in advance should I book a flight from Santiago to Medellín Jose Maria Cordova Intl Airport?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to Medellín Jose Maria Cordova Intl Airport, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to Medellín Jose Maria Cordova Intl Airport, you should book around 6 weeks before departure. For the absolute cheapest price, our data suggests you should book 12 weeks before departure.

Good to know

Low seasonApril
High seasonDecember
Cheapest flight$177
Best time to beat the crowds but there is an average 6% increase in price.
Most popular time to fly with an average 13% increase in price.
Flight from Santiago to Medellín

When to book flights from Santiago to Medellín

Are your dates flexible? Find out the best times to travel from Santiago to Medellín based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Santiago to Medellín flights

  • How many flights are there between Santiago and Medellín Jose Maria Cordova Intl Airport per day?

    There is a maximum of 1 nonstop flight a day that takes off from Santiago and lands in Medellín Jose Maria Cordova Intl Airport, with an average flight time of 6h 15m. The most common departure time is 1:00 am and most flights take off at night. Each week, there are 4 flights.

  • What is the cheapest flight from Santiago to Medellín Jose Maria Cordova Intl Airport?

    In the last 3 days, the lowest price for a flight from Santiago to Medellín Jose Maria Cordova Intl Airport was $177 for a one-way ticket and $310 for a round-trip.

  • Do I need a passport to fly between Santiago and Medellín?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santiago and on arrival in Medellín.

  • Which airports will I be using when flying from Santiago to Medellín?

    Santiago airport is called Santiago Arturo Merino Benitez and the only airport in Medellín is Medellín Jose Maria Cordova Intl.

  • Which airlines offer Wi-Fi service onboard planes from Santiago to Medellín?

    Only American Airlines offers inflight Wi-Fi service on the Santiago to Medellín flight route.

  • Which aircraft models fly most regularly from Santiago to Medellín?

    The Boeing 787-8 Dreamliner is the aircraft model that flies most regularly on the Santiago to Medellín flight route.

  • Which airline alliances offer flights from Santiago to Medellín?

    Star Alliance is the only airline alliance operating flights between Santiago and Medellín.

  • On which days can I fly direct from Santiago to Medellín?

    You can catch a nonstop flight from Santiago to Medellín on Monday, Tuesday, Thursday, and Saturday.

  • Which is the best airline for flights from Santiago to Medellín, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Santiago to Medellín are Copa Airlines and LATAM Airlines. With an average price for the route of $336 and an overall rating of 7.5, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $374 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Santiago to Medellín?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to Medellín.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to Medellín?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Medellín from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to Medellín?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Medellín with an airline and back to Santiago with another airline. Booking your flights between Santiago and MDE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to Medellín?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Medellín from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santiago to Medellín Jose Maria Cordova Intl Airport

  • Looking for a cheap flight? 25% of our users found flights on this route for $351 or less one-way and $401 or less round-trip.

Prefer to fly direct from Santiago to Medellín?

Find which airlines fly direct from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport, which days they fly and book direct flights.

Direct departures

Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl

Monday

Avianca

Avianca

Tuesday

Avianca

Avianca

Thursday

Avianca

Avianca

Saturday

Avianca

Avianca

See more direct flights

Direct returns

Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez

Monday

Avianca

Avianca

Wednesday

Avianca

Avianca

Friday

Avianca

Avianca

Sunday

Avianca

Avianca

See more direct flights
See more direct flights

Top 4 airlines serving from Santiago to Medellín

 
See real verified KAYAK customer reviews for airlines flying from Santiago to Medellín. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to Medellín? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1769 reviews
7.6Boarding
6.7Food
7.0Entertainment
7.4Comfort
8.1Crew
Airline reviews

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

8.0 ExcellentPaul, Apr 2025BOG - SCL
Read more LATAM Airlines reviews

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Change of gate in Santiago devolved into half plus hour delay and a really tight connection in Lima

Although the flight is goof and the crew is good, the way the airline charges you for every service is ridiculous.

They didi not provide wheelchair though we had requested. We had to run around for 40 minutes and arrange it from the airport!

I liked everything, this was classed as premium economy but it was much better than Lufthansas business class. Lovely staff, comfortable plane and an excellent seat arrangement. A very pleasant surprise.

Everything was good except the check in. Could not do it online neither on the machines in the airport. Needed special assistance from the airline desk clerk

Friendly staff, It was the first flight out for our plane, so had to be deiced from the frost. Only delayed a few minutes,

Staff encountered friendly and helpful. Flight delayed 1 hour due to mechanical issue, but made it through Atlanta immkgration and security in plenty of time,

reliable, relatively relaxed, helpful and kind staff and clean airplanes. No need for more.

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

My flight delayed and i misss the connection they send me to orlando no to tampa i have to pay a uber to my house

I upgraded myself to Business Class at the last minute so I had a DREAMS window seat. Seeing as I've never flown Business before everything was novel and fun for me and it made the 7 hour flight much more enjoyable for sure.

No headphones given for inflight entertainment. I missed my flight from the previous day and the customer service agent tried to extort an additional $100.00 US from me for missing my flight. Really?!

It was reasonably comfortable trip considering its duration (7 hours). Crew was very good and friendly, seats very more comfortable than other planes. Only negative comment would be that the bathroom light did not get its full brightness 🙃

The flight was delayed about 4 hours without any explanation. No wifi or entertainment at all on planes. Had to pay for checked bags I was allowed according to reservations.

It was good, plane is a bit older so seats are somewhat flat

Great from check in all the way to the end. Very happy with Copa

Copa stranded us ans then tried to charge us thousands to leave Panama.

Well the airline was fine. The only thing is I was charged for a checked in luggage. But when I reserved the ticket it showed a check in bag allowed. Who can I get in contact with for reimbursement.? The airline said I had to speak to whoever I booked ticket with.

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

I receive a service for what I pay, so it is fair.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Purchased a business class ticket and got a economy seat with center seat blocked they call it business. 3100usd ticket on a flight where economy costs 500usd The biggest scam insult have had on a regular airline. Avianca should be in the low cost category and kicked out of Star Alliance. I want the difference to be credited. Ets see what Avianca does. No reply so far. Avianca = low cost airline. Beware

Excellent flight and one of the smoothest landing I’ve ever experienced

The seats were very uncomfortable. I would have upgrade or got different flight if I knew. I usually sleep in the plane but I couldn’t sleep at all. Very uncomfortable. Also no food or drink everything was to purchase, and that’s u usual for international flight.

We did not know about the bag fees until check in. They are way too high. It’s insane. We also had a huge delay and everything costed extra which was very annoying.

Boarding was somewhat confusing in that the wrong messages were being displayed at the gate. It was somewhat annoying that I got off one flight and straight onto another (from the same gate), but in between they re-checked my hand luggage and made me get rid of my water (which they charge for on the plane). I was sitting in their 'Plus' seating, but the leg room was still too small to be able to sit square. The food options on the flights are pretty cheap quality (but not price). They got me from 'A' to 'B' on-time and for a relatively good price, but the experience itself was below average.

Lounge for business was closed. Boarding was rush and stand by. Seat for business is just the middle seat blocked and some more leg room.

Flew with our two children. Paid $380 to check two bags (one was overweight). They then left the bags behind on Sunday, December 21st, with all our family’s clothes and family Christmas presents. When we arrived at our destination they told us the bags had not arrived, and they thought (but didn’t know) they were still in Boston, but that there’d be a flight the next day and the bags would arrive the next day. The next day we found out there was no flight, now we’re hoping we get our bags before we fly back out. Meanwhile, trying to get any engagement or accurate information is a waste of time. The folks at the call center are just gatekeepers, who can’t connect with any departments that actually do things to solve a problem. Getting information is made deliberately difficult. My biggest regret is that I’ve had a number of awful experiences with Avianca traveling between the US and Colombia, and still let myself get suckered into buying these tickets because the schedule was great. Never again.

Customer service is horrible. Our flight was at 9pm and we were at check in counter by 7pm. The crew strolls in at 7.30 without even an apology. We were suppose to get our boarding passes online but the website was not working at expected and the staff kept arguing with us saying that is not possible.

There was no entertainment but everyone just used their phones.

The app told us that carry on luggage was included but we were made to pay for it again at the check in counter, making it a very expensive flight. Not happy

I was charged 168 soles for kids stroller. We have travelled across the world and have never charged for the stroller. Horrific airlines and the staff was extremely rude. They wouldn’t let us board unless we pay the extra baggage cost. Never ever flying this airline and I would recommend the same for the others.

Avoid this airline. They are unprofessional. The captain left several passengers on ground due to covid restrictions which were never communicated. As a chilean, I am ashamed that this low level airline comes from my country. Remember this horrible brand and avoid it... Jetsmart

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