SCL - MDE

$139 Find Cheap Flights from Santiago to Medellín

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Santiago to Medellín departing on 5/31. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Medellín Jose Maria Cordova Intl Airport

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Medellín, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Santiago to Medellín, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$289
Typical prices: $345-$435
JetSMART
Sun 5/31Mon 6/15
SCL - MDE • Non-stop
Cheapest one-way
$139
Typical prices: $160-$225
JetSMART
Sun 5/31
SCL - MDE • Non-stop
Advice from real travelers
AI-powered summary based on content written by travel experts. AI can make mistakes.
Avianca's Classic fare includes a carry-on and checked bag.
JetSMART's low-cost fares include only a small handbag.
Expert advice
Expert advice
Expert advice
Expert advice
Nonstop flights
5 days a week
Mon, Tue, Wed, Fri, Sat
You can fly direct with JetSMART. Average duration is 6h 15m
Direct flights
Direct flights
+1
+1
Direct flights
Direct flights
+1
Top airlines
JetSMART
Cheapest • from $289 (round-trip)
Copa Airlines
Best reviews • 7.5 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
Top layover airports
Panama City (PTY)
Cheapest • Avg $415 (round-trip)
Lima (LIM)
Shortest trip • 9h 34m (one-way)
Insights
Insights
Insights
Insights
Avoid delays
JetSMART
Most punctual • 77% on-time
Afternoon flights
Best time • Fewest delays
Insights
Insights
Insights
Insights
When to book
7 weeks
in advance
Our data shows that travelers who book at least 7 weeks in advance save around 19% compared to booking last minute.
Insights
Insights
Insights
Insights
When to travel
March
Cheapest • 10% price drop
December
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Medellín!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Santiago to Medellín (SCL-MDE)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Santiago to Medellín that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Santiago to Medellín

Sun, May 31 - Mon, Jun 15
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$289JetSMART
Sun, May 31 - Sun, Jun 14
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$291JetSMART
Sun, Jun 7 - Fri, Nov 6
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:01 pm - 1:09 am
MDE
-
SCL
6h 08mnonstop
$292JetSMART
Thu, Jul 2 - Fri, Jul 10
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$295JetSMART
Fri, Jun 5 - Fri, Nov 6
JetSMART Logo
8:31 am - 4:40 pm
SCL
-
MDE
9h 09m
1 stop
JetSMART Logo
5:01 pm - 1:09 am
MDE
-
SCL
6h 08mnonstop
$298JetSMART
Mon, Jun 29 - Mon, Jul 6
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$299JetSMART
Mon, Jun 29 - Mon, Jul 6
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$301JetSMART
Fri, May 15 - Thu, Jun 11
JetSMART Logo
4:56 am - 4:40 pm
SCL
-
MDE
12h 44m
1 stop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$302JetSMART
Mon, Jun 29 - Mon, Jul 6
JetSMART Logo
1:11 am - 6:35 am
SCL
-
MDE
6h 24mnonstop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$303JetSMART
Mon, Jun 8 - Sun, Jun 14
JetSMART Logo
4:56 am - 4:40 pm
SCL
-
MDE
12h 44m
1 stop
JetSMART Logo
5:01 pm - 12:11 am
MDE
-
SCL
6h 10mnonstop
$304JetSMART
Booking Insights

KAYAK's insights & trends for Santiago to Medellín flights

Get data-powered insights and trends into flights from Santiago to Medellín to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Santiago to Medellín Jose Maria Cordova Intl Airport?

This analysis is based on the cheapest round-trip price found on KAYAK in the last 12 months by searching for a flight from Santiago to Medellín Jose Maria Cordova Intl Airport departing in July.

What’s the cheapest day of the week to fly from Santiago to Medellín?

The average price of all round-trip flights from Santiago to Medellín Jose Maria Cordova Intl Airport clicked on KAYAK for each day over the last 12 months.

Your flight ticket price will generally be cheaper if you fly to Medellín on a Tuesday and more expensive on a Sunday. On your return trip to Santiago, you should consider flying back on a Wednesday, and avoid Fridays for better deals.

What is the cheapest month to fly from Santiago to Medellín Jose Maria Cordova Intl Airport?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Santiago to Medellín Jose Maria Cordova Intl Airport, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Santiago to Medellín Jose Maria Cordova Intl Airport is March, where tickets cost $337 (return) on average. On the other hand, the most expensive months are January and February, where the average cost of round-trip tickets is $413 and $398 respectively.

Can I save money by flying with a layover from Santiago to Medellín Jose Maria Cordova Intl Airport?

The average round-trip price for all non-stop flights, flights with one layover, and flights with two layovers for the route found by users searching on KAYAK in the last 2 weeks.

No, with an average price for the route of $704, prices are generally cheapest when you fly direct.

How far in advance should I book a flight from Santiago to Medellín Jose Maria Cordova Intl Airport?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Santiago to Medellín Jose Maria Cordova Intl Airport, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Santiago to Medellín Jose Maria Cordova Intl Airport, you should book around 7 weeks before departure, which saves you about 19% compared to booking last minute. For the absolute cheapest price, our data suggests you should book 19 weeks before departure.

Expert advice

Expert advice for your flight from Santiago to Medellín

 
AI-powered summary based on content written by travel experts. AI can make mistakes.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Daniel Scheffler

Daniel Scheffler

Expert on JetSMART

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Mark Chesnut

Mark Chesnut

Expert on Avianca

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Good to know

Low seasonSeptember
Cheapest flight$139
Most popular time to fly with an average 5% increase in price.
Flight from Santiago to Medellín

When to book flights from Santiago to Medellín

Are your dates flexible? Find out the best times to travel from Santiago to Medellín based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Santiago to Medellín flights

  • What is the cheapest flight from Santiago to Medellín Jose Maria Cordova Intl Airport?

    In the last 3 days, the lowest price for a flight from Santiago to Medellín Jose Maria Cordova Intl Airport was $139 for a one-way ticket and $289 for a round-trip.

  • Do I need a passport to fly between Santiago and Medellín?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Santiago and on arrival in Medellín.

  • Which airports will I be using when flying from Santiago to Medellín?

    Santiago airport is called Santiago Arturo Merino Benitez and the only airport in Medellín is Medellín Jose Maria Cordova Intl.

  • Which aircraft models fly most regularly from Santiago to Medellín?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Santiago to Medellín flight route.

  • Which airline alliances offer flights from Santiago to Medellín?

    Star Alliance is the only airline alliance operating flights between Santiago and Medellín.

  • On which days can I fly direct from Santiago to Medellín?

    You can catch a nonstop flight from Santiago to Medellín on Monday, Tuesday, Wednesday, Friday, and Saturday.

  • Which is the best airline for flights from Santiago to Medellín, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Santiago to Medellín are Copa Airlines and LATAM Airlines. With an average price for the route of $392 and an overall rating of 7.5, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $414 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Santiago to Medellín?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Santiago to Medellín.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Santiago to Medellín?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Medellín from Santiago is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Santiago to Medellín?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Medellín with an airline and back to Santiago with another airline. Booking your flights between Santiago and MDE can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Santiago to Medellín?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Medellín from Santiago up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

KAYAK’s top tips for finding a cheap flight from Santiago to Medellín Jose Maria Cordova Intl Airport

  • Looking for a cheap flight? 25% of our users found flights on this route for $173 or less one-way and $372 or less round-trip.

Prefer to fly direct from Santiago to Medellín?

 
Direct data is based off flight results for the next 60 days. Find direct flights from all airlines flying direct from Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl.
Find which airlines fly direct from Santiago Arturo Merino Benitez Airport to Medellín Jose Maria Cordova Intl Airport, which days they fly and book direct flights.

Direct departures

Santiago Arturo Merino Benitez to Medellín Jose Maria Cordova Intl

Monday

JetSMART

JetSMART

Tuesday

JetSMART

JetSMART

Wednesday

JetSMART

JetSMART

Friday

JetSMART

JetSMART

Saturday

JetSMART

JetSMART

See more direct flights

Direct returns

Medellín Jose Maria Cordova Intl to Santiago Arturo Merino Benitez

Monday

JetSMART

JetSMART

Tuesday

JetSMART

JetSMART

Thursday

JetSMART

JetSMART

Friday

JetSMART

JetSMART

Sunday

JetSMART

JetSMART

See more direct flights

Reviews of the top 4 airlines serving from Santiago to Medellín

 
See real verified KAYAK customer reviews for airlines flying from Santiago to Medellín. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Santiago to Medellín? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
Copa AirlinesOverall score based on 1557 reviews
6.8Entertainment
8.1Crew
7.4Comfort
7.8Boarding
6.8Food
Airline reviews

Flight got delayed; had to go through security three times.

2.0 MediocreAnonymous, Feb 2026
PTY - JFK
Read more Copa Airlines reviews

Flight got delayed; had to go through security three times.

A lot things happened in this trip.The fly should be less stress.

Horrible. No TV or any type of entertainment on board. Passwnger listening to/watching stuff on their own phone with no headphones making it noise and uncomfortable for everyone else, little/tiny food portions, old seats, useless wifi (cant access anything). Horrible exlerience especially it was a lomg distance flight with kids.

There should be a warning regarding the quality of the aircraft on the website as we reserve the tickets. There was no TV or any type of screen onboard. The wifi they offer is good for nothing. Traveling 9 hours straight with kids and no type of entetainment was horrible. I wish I had been informed prior so I could buy a ticket with another airline. The food was a joke too. A very tiny portion per passenger. They also charged $100 per checked bag. With United I used to pay $60. So, fair to say that I wont be flying Copa anymore. Their aircraft was super old, outdated, no entertainment, with nearly no onboard food.

I always enjoy flying Copa. There are very few airlines where I can enjoy a comfortable sleep in-flight. The snacks weren't the best, but they sufficed. The in-flight entertainment was fantastic, and I crossed another movie off my watch list.

Simply as follows:- First, there was no vegetarian option for the meal Second, only 2 washrooms for the entire economy class.

They were super friendly bumped me up to exit row free of charge, All flight legs were on time

Boarding was quick & efficient; they gave boarding groups due priority; staff & air crew were very cordial and helpful, pleasant flight.

As always, Copa Airlines is great to fly on. The flights are always on time, the staff are pleasant and helpful and it's always a wonderful flying experience.

Great experience with a crew always thinking in the passenger

Nothing I like, I missed this connection b/c of an earlier flight delay. I had to stay one more night and I paid out my own pocket. LATAM failed to send me to a safe and decent hotel.

It was delayed for 2 hours. Then when we arrived they took us on a very uncomfortable bus and left us there. The bus driver wouldn't let us out because no one from Latam was there. Everything was disaster.

LATAM is a great airline who takes care of there guests. They consistently walk around and see if you need water in addition to taking care of all the passengers. The chicken in process is really easy and I’m always offered a chance for an upgrade which I appreciate.

On board crew was very good. Crew was friendly, snacks were good, especially the chips. Seats seemed a bit cramped. Boarding seemed unorganized, as we were instructed to get to the gate an hour early and then just stood around until boarding.

Latam wouldn’t tell me how much checked luggage would until I was at the airport and they charged me the highest price possible. Besides that, it was okay.

LATAM’s crews are fine, but God help you if you need any customer service. Their app and website never work, with error after error. Trying to solve anything over the phone is painful, and lastly, the boarding pass LATAM gave me to board the flight with Delta was invalid and I had to purchase an emergency one-way ticket at the last minute to get home.

We traveled with two young children, and it was not possible for our family to be seated together. No one offered help or assistance to organize seating so we could sit with our kids. In the end, we managed to find two seats in Economy so I could at least sit with one of them, even though I had originally paid for Comfort+. In summary, I had to downgrade my seat just to be able to sit with one of my children, which was very disappointing

Good flight, boarding ok and crew very nice. Flight was not full so I was able to be very comfortable. Blanket and pillow provided with was good as it was very cold during the flight . Food was very good(small snack sandwich and an excellent piece of orange cake). Overall good flight, no complaints.

Latam may be the worst airline in the world, far worse than even the lowest of low cost airlines in the USA. I wasted hours trying to PAY THEM TO CHECK A BAG! Then they misled me at the terminal, sent me through the wrong security line, the list goes on and on... Just absolutely terrible in every way. Avoid at all costs.

Poor, the airline was not able to help me move flights.

First of all, could be Kyak's fault he we couldn't for days check in on line via Kayak or Jet Smart. We can't get the app either. Luckily on LATAM I managed to get the WiFi and contact Jet smart via what's app. This was horrendous and the person was unhelpful to start with. But we explained and she managed to check us in as if she didn't we wouldn't have got on the flight as would've been too late to check in. At the gate they were checking everyone's bag for size. My bag was 1 cm over and they tried to charge me $255 soles to carry it on but was 225 to put it in the hold. We had to pay to put both bags in the hold adding £100 to the cost of the flight. We had to carry the bags as the jet smart sight doesn't allow us to add bags which would've cost us £13 each so £26 on booking instead of £100. Staff at the gate were rude to us and other passengers. I'm sure they were on commission to get money off passengers for the bags. The lady flight attendant was pleasant but over ruled buy this jumped up young guy when I asked if my partner could sit beside me. The plane was 1/3 full. Then he was rude most of the flight. Avoid jet smart at all costs! Worrying thing is we have a return journey with these shower of.... We have been on their site the past two days trying to add bags but site won't do anything. I think this is on purpose to get more money out of passengers. As I said avoid at all costs.

Terrible website. Does not work most of the time I tired using it to check in. Had to have someone from another country help me check in. Their customer service is the worst.

The crew was polite, the Captain specially was cool! But the onboard service was nonexistent: No entertainment, no food, no reclining seats. I know it is a low cost, but the cost of the ticket was not so low for just the transport service.

Was a good flight, no delays and good customer service.

Customer service is horrible. Our flight was at 9pm and we were at check in counter by 7pm. The crew strolls in at 7.30 without even an apology. We were suppose to get our boarding passes online but the website was not working at expected and the staff kept arguing with us saying that is not possible.

There was no entertainment but everyone just used their phones.

The app told us that carry on luggage was included but we were made to pay for it again at the check in counter, making it a very expensive flight. Not happy

I was charged 168 soles for kids stroller. We have travelled across the world and have never charged for the stroller. Horrific airlines and the staff was extremely rude. They wouldn’t let us board unless we pay the extra baggage cost. Never ever flying this airline and I would recommend the same for the others.

Avoid this airline. They are unprofessional. The captain left several passengers on ground due to covid restrictions which were never communicated. As a chilean, I am ashamed that this low level airline comes from my country. Remember this horrible brand and avoid it... Jetsmart

Horrible experience with Avianca, they delayed their flight and when we arrived to NYC, AVIANCA took 1 hr y 30 mins to park the airplane and all passenger get off the plane, it made me lost all my trains to get back home and I came back to my place at 3 am instead of 12 am. On the top of that their plane seat are so uncomfortable and is not enough space and killed my legs and knees, Avianca used to be good when it was a Colombian company, now after Brasilian company bought them, their service quality is bad and their flights are delayed and oversold.

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral and avianca lost my check in luggage

It was delayed and I lost my connection flight to Cali and I missed my Mom's funeral

I actually upgraded to the medium level of seats from basic and even doing that it may have been physically the most uncomfortable flight I have ever had. They packed everyone like is a train to death camp. It was a red eye so I hoped to get some sleep but it was physically impossible to find a comfortable way to rest. I met other folks on the same flight and they said the same thing. It was an utterly miserable flight and if I have any other options I will never fly with them again

only a bag of chips and a bottle of water in business class was served

Avianca has transitioned from full service legacy airline to "low cost" but has now became a strange hybrid (minimum leg space, started offering business class in domestic flights again, charges passenger for printing boarding pass, etc.). National and international coverage and destinations are really wide but service is not at its best

We found the chairs to be really uncomfortable. It’s also really unacceptable that no form of food or drink is included in a 6+ hour flight

Not good, tried to purchase a first class upgrade and they couldn’t get it done. Was super uncomfortable the whole time.

Deplaning was a mess, I sat in business (seats are horrible) and the front door had a problem so we had to deplane from the rear exit. The stairs were not tall enough to reach so there was a large step down from the plane to the top of the stairs.

Pros: we leave and arrive on time Cons: the most uncomfortable seats ever. You cant recline at all your seats. No entertainment No TVs flight attendants didn't provide even a glass of water. You have to go to back of the airplane and ask for one. I am Colombian and I remember seeing the flight attendants very neat, elegants which is or was a staple of Avianca.it was one with tennis shoes, no male up, the hair was messy... that was really odd.

Everything you need to know for your flight from Santiago to Medellín

Information on your arrival and departure airports