$509 Find Cheap Flights from Des Moines to the Czech Republic

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to the Czech Republic departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to the Czech Republic

Travelers love KAYAK
41.299.237 searches in the past 7 days on KAYAK

Save 23% or moreCompare multiple travel sites with one search.

Track pricesNot ready to book? Create a price alert for when prices drop.

Bundle and saveSave money when you bundle your flight + hotel.

Filter your dealsChoose cabin class, free Wi-Fi and more.

Flight Deals
Booking Insights
Flight Deals

Book Cheap Des Moines to the Czech Republic Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to the Czech Republic that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to the Czech Republic

Wed, Mar 18 - Wed, Mar 25
Delta Logo
11:33 am - 11:40 am
DSM
-
PRG
18h 07m
2 stops
Delta Logo
11:35 am - 10:48 am
PRG
-
DSM
29h 13m
2 stops
$510Delta
Fri, May 1 - Sun, May 10
British Airways Logo
5:01 pm - 10:50 pm
DSM
-
PRG
22h 49m
2 stops
British Airways Logo
9:20 pm - 11:49 pm
PRG
-
DSM
33h 29m
2 stops
$597British Airways
Fri, May 1 - Sun, May 10
United Airlines Logo
11:40 am - 8:55 am
DSM
-
PRG
14h 15m
2 stops
United Airlines Logo
9:10 am - 10:45 pm
PRG
-
DSM
20h 35m
2 stops
$611United Airlines
Fri, May 1 - Sun, May 10
Lufthansa Logo
8:10 pm - 11:10 pm
DSM
-
PRG
20h 00m
2 stops
Lufthansa Logo
2:10 pm - 11:09 pm
PRG
-
DSM
15h 59m
2 stops
$634Lufthansa
Wed, Mar 4 - Sun, Mar 8
United Airlines Logo
9:04 am - 4:05 pm
DSM
-
PRG
24h 01m
2 stops
United Airlines Logo
7:25 am - 8:40 pm
PRG
-
DSM
20h 15m
2 stops
$711United Airlines
Wed, Mar 4 - Sun, Mar 8
United Airlines Logo
8:00 am - 4:05 pm
DSM
-
PRG
25h 05m
2 stops
United Airlines Logo
6:15 am - 9:44 pm
PRG
-
DSM
22h 29m
2 stops
$713United Airlines
Mon, Apr 6 - Mon, Apr 13
Delta Logo
10:51 am - 5:40 pm
DSM
-
PRG
23h 49m
2 stops
Delta Logo
2:30 pm - 3:41 pm
PRG
-
DSM
32h 11m
2 stops
$763Delta
Sun, Apr 5 - Sun, Apr 12
Lufthansa Logo
6:59 pm - 9:20 pm
DSM
-
PRG
19h 21m
2 stops
Lufthansa Logo
2:10 pm - 10:59 pm
PRG
-
DSM
15h 49m
2 stops
$766Lufthansa
Sun, Apr 5 - Sun, Apr 12
Multiple Airlines Logo
1:10 pm - 5:55 pm
DSM
-
PRG
21h 45m
2 stops
Multiple Airlines Logo
2:10 pm - 10:59 pm
PRG
-
DSM
15h 49m
2 stops
$794Multiple Airlines
Thu, Apr 2 - Thu, Apr 9
British Airways Logo
1:37 pm - 11:20 pm
DSM
-
PRG
26h 43m
2 stops
British Airways Logo
10:05 am - 7:33 pm
PRG
-
DSM
16h 28m
2 stops
$796British Airways
Booking Insights

KAYAK's insights & trends for Des Moines to the Czech Republic flights

Get data-powered insights and trends into flights from Des Moines to the Czech Republic to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to the Czech Republic?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to the Czech Republic were found on Delta ($510) and British Airways ($597).

Find deals

Good to know

Cheapest flight$509
Flight from Des Moines to Prague

FAQs - booking Czech Republic flights

  • How does KAYAK find such low prices on flights from Des Moines to the Czech Republic?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to the Czech Republic.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to the Czech Republic?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to the Czech Republic is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to the Czech Republic?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to the Czech Republic with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to the Czech Republic?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to the Czech Republic up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to the Czech Republic

 
Need help choosing which airline to fly with from Des Moines to the Czech Republic? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9325 reviews
8.1Crew
7.1Entertainment
7.7Boarding
7.3Comfort
6.6Food
Airline reviews

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

8.0 ExcellentMaureen, Feb 2026
SMF - DEN
Read more United Airlines reviews

Women boarding passengers at the gate was absolutely rude and disrespectful of passengers. The flight attendant was absolutely delightful! Smiling and connected with the passengers. So happy. The seats are cramped and uncomfortable but I guess that’s just the way it is Communication regarding flight was excellent

Overall we had a good experience during our flight from San Francisco to Houston.

Airport terminal was outdated, flight was on a small jet with no wifi

We were delayed for about an hour from taking off due to traffic control procedures at the destination airport. But once in the air, the flight went well. The crew members were great and provided cabin service despite moderate turbulence during much of the flight.

it was a very short flight so my expectations were low.

As great a red-eye flight as red-eye flights can be.

Once boarding started it was pretty quick. Food was inedible; cold and salty..

Entertainment kept turning itself off. Gave up on watching a movie.

Both the WIFI and entertainment did not work for 2.5h

The crew made our experience extremely bad. They were rude and didn’t have anything for kids.

Everything you need to know for your flight from Des Moines to the Czech Republic

Information on your arrival and departure airports

Des Moines (DSM)