$371 Find Cheap Flights from Des Moines to the Czech Republic

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to the Czech Republic departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Des Moines to the Czech Republic Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to the Czech Republic that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to the Czech Republic

Tue, Apr 7 - Mon, Apr 20
British Airways Logo
11:58 am - 4:25 pm
DSM
-
PRG
21h 27m
2 stops
British Airways Logo
8:55 pm - 11:29 pm
PRG
-
DSM
33h 34m
2 stops
$462British Airways
Sun, Mar 1 - Sun, Mar 8
American Airlines Logo
11:17 am - 1:35 pm
DSM
-
PRG
19h 18m
2 stops
American Airlines Logo
6:50 am - 6:00 pm
PRG
-
DSM
18h 10m
2 stops
$476American Airlines
Sun, Mar 1 - Sun, Mar 8
Finnair Logo
11:17 am - 6:50 pm
DSM
-
PRG
24h 33m
2 stops
Finnair Logo
7:35 pm - 11:42 pm
PRG
-
DSM
34h 07m
2 stops
$477Finnair
Sat, Feb 28 - Sat, Mar 7
British Airways Logo
1:38 pm - 10:50 pm
DSM
-
PRG
26h 12m
2 stops
British Airways Logo
7:40 am - 10:19 pm
PRG
-
DSM
21h 39m
2 stops
$494British Airways
Fri, Apr 10 - Fri, Apr 17
British Airways Logo
11:58 am - 10:50 pm
DSM
-
PRG
27h 52m
2 stops
British Airways Logo
7:05 am - 11:29 pm
PRG
-
DSM
23h 24m
2 stops
$495British Airways
Sat, Feb 28 - Sat, Mar 7
United Airlines Logo
3:24 pm - 1:05 pm
DSM
-
PRG
14h 41m
2 stops
United Airlines Logo
7:35 am - 8:27 pm
PRG
-
DSM
19h 52m
2 stops
$501United Airlines
Tue, Apr 7 - Wed, Apr 15
United Airlines Logo
8:04 am - 12:45 pm
DSM
-
PRG
21h 41m
3 stops
United Airlines Logo
9:10 am - 11:42 pm
PRG
-
DSM
21h 32m
2 stops
$509United Airlines
Thu, Apr 9 - Wed, Apr 15
British Airways Logo
5:00 pm - 5:05 pm
DSM
-
PRG
17h 05m
2 stops
British Airways Logo
10:30 am - 7:31 pm
PRG
-
DSM
16h 01m
2 stops
$512British Airways
Thu, Feb 5 - Mon, Feb 9
British Airways Logo
5:01 pm - 6:25 pm
DSM
-
PRG
42h 24m
2 stops
British Airways Logo
9:35 pm - 4:24 pm
PRG
-
DSM
49h 49m
2 stops
$517British Airways
Thu, Feb 5 - Mon, Feb 9
British Airways Logo
5:01 pm - 6:25 pm
DSM
-
PRG
42h 24m
2 stops
British Airways Logo
9:35 pm - 4:24 pm
PRG
-
DSM
49h 49m
2 stops
$518British Airways
Booking Insights

KAYAK's insights & trends for Des Moines to the Czech Republic flights

Get data-powered insights and trends into flights from Des Moines to the Czech Republic to help you find the cheapest flights, the best time to fly and much more.

How long does a flight from Des Moines to the Czech Republic take?

The duration of a flight to the Czech Republic depends on your arrival airport. The shortest route to the Czech Republic from Des Moines is to Prague, which takes 14h 41m.

Good to know

Cheapest flight$407
Flight from Des Moines to Prague

FAQs - booking Czech Republic flights

  • How does KAYAK find such low prices on flights from Des Moines to the Czech Republic?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to the Czech Republic.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to the Czech Republic?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to the Czech Republic is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to the Czech Republic?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to the Czech Republic with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to the Czech Republic?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to the Czech Republic up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to the Czech Republic

 
Need help choosing which airline to fly with from Des Moines to the Czech Republic? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9164 reviews
6.6Food
8.1Crew
7.1Entertainment
7.7Boarding
7.3Comfort
Airline reviews

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

10.0 ExcellentDavid, Jan 2026
IAD - BNA
Read more United Airlines reviews

Was happy we finally got upgraded in 1st class. The seat getting old. The cushiness need some improvement.

Yet another flight in which beverage and snack service was skipped. Other that that, firmly mediocre. Landed early, to gate late due to congestion at the gates. Airline's fault or airports fault: unknown.

Ineffective communication with United resulted in lost baggage. Their Baggage Tracing counter at MUC was shut down from 11:00-14:15 on my arrival. Undertrained, underinformed staff had me Running all over MUC to find someone to help me to no avail. Staff was rude, unhelpful, and unable to effectively use the systems they did have operational. They refused to contact United in any way or provide any accommodation or other resources while I waited for my luggage. This has destroyed my downstream itinerary. If they had even the slightest visibility I may have been able to reschedule/plan, but again, their staff provided nothing, and did nothing more than their website, which doesn’t even work on a standard phone browser. Miserable failure at all levels that weren’t associated with the operation of the aircraft.

Miserable. They moved my seat, but canceled the next leg of my flight. I resolved the issue at my transfer, but that resulted in lost luggage that has taken days off my schedule with no resolution. Worse, they fail to interface effectively with Lufthansa, forcing me to bounce between two equally useless help desks. The apps are unable to handle the situation, the bag dropped off the tracker, and while the call centers are polite, they do not provide written information to assist with cross-airline communication.

left on time, reasonable boarding process arrived early luggage came out quickly

I like flying first class, and United has a nice one

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

Check-in, boarding and the flight from Phoenix to Houston was quick and easy. The flight from Houston to Shreveport was delayed 5 hours. It was frustrating but I think United handled it the best they could.

Some flight attendants were great others were cranky. Seats were very tight and sitting on an aisle was very hard as the carts and people walking constantly bumped shoulder and arm.

It was great with United overall except for two things. 1) It was a 5-hour flight and we were with kids, so we were asking for extra snacks. They were extremely reticent to dole them out even though there wasn't any meal and the kids were starting to hit their limit towards the end. 2) Baggage didn't arrive until 80 minutes after we landed.

Everything you need to know for your flight from Des Moines to the Czech Republic

Information on your arrival and departure airports