$437 Find Cheap Flights from Des Moines to the Czech Republic

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to the Czech Republic departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Des Moines to the Czech Republic Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to the Czech Republic that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to the Czech Republic

Sat, Dec 6 - Sat, Dec 13
United Airlines Logo
6:50 pm - 1:05 pmDSM-PRG
35h 15m2 stops
United Airlines Logo
1:45 pm - 10:29 pmPRG-DSM
39h 44m2 stops
$516United Airlines
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Fri, May 1 - Sun, May 10
Lufthansa Logo
11:30 am - 8:55 amDSM-PRG
14h 25m2 stops
Lufthansa Logo
6:10 am - 9:36 pmPRG-DSM
22h 26m2 stops
$781Lufthansa
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Wed, Dec 24 - Wed, Dec 31
United Airlines Logo
8:00 am - 5:55 pmDSM-PRG
26h 55m2 stops
United Airlines Logo
6:15 am - 9:40 pmPRG-DSM
22h 25m2 stops
$801United Airlines
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Wed, Dec 24 - Wed, Dec 31
United Airlines Logo
8:00 am - 5:55 pmDSM-PRG
26h 55m2 stops
United Airlines Logo
6:50 am - 9:40 pmPRG-DSM
21h 50m2 stops
$802United Airlines
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Fri, Mar 27 - Tue, Mar 31
United Airlines Logo
3:15 pm - 10:50 amDSM-PRG
13h 35m2 stops
United Airlines Logo
6:00 am - 5:55 pmPRG-DSM
18h 55m2 stops
$805United Airlines
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Wed, Dec 24 - Wed, Dec 31
Multiple Airlines Logo
12:10 pm - 10:50 amDSM-PRG
15h 40m2 stops
Multiple Airlines Logo
6:00 am - 4:52 pmPRG-DSM
17h 52m2 stops
$1,212Multiple Airlines
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Thu, Dec 25 - Thu, Jan 1
Multiple Airlines Logo
12:10 pm - 7:35 pmDSM-PRG
24h 25m2 stops
Multiple Airlines Logo
6:00 am - 8:02 pmPRG-DSM
21h 02m2 stops
$1,434Multiple Airlines
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Thu, Dec 25 - Thu, Jan 1
Delta Logo
12:10 pm - 5:35 pmDSM-PRG
22h 25m2 stops
Delta Logo
6:30 am - 8:02 pmPRG-DSM
20h 32m2 stops
$1,887Delta
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Fri, May 1 - Sun, May 10
Air Canada Logo
11:30 am - 12:45 pmDSM-PRG
18h 15m3 stops
Air Canada Logo
6:10 am - 5:33 pmPRG-DSM
18h 23m3 stops
$2,005Air Canada
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Fri, May 1 - Sun, May 10
Air Canada Logo
11:30 am - 12:45 pmDSM-PRG
18h 15m3 stops
Air Canada Logo
6:10 am - 5:33 pmPRG-DSM
18h 23m3 stops
$2,006Air Canada
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Booking Insights

KAYAK's insights & trends for Des Moines to the Czech Republic flights

Get data-powered insights and trends into flights from Des Moines to the Czech Republic to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Des Moines and Czech Republic?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Des Moines to the Czech Republic.

There is just one airline that flies from Des Moines to the Czech Republic direct and that is United Airlines. The best round-trip deal found from United Airlines for the route is to Prague (PRG) and costs $597.

Which airlines provide the cheapest flights from Des Moines to the Czech Republic?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to the Czech Republic were found on United Airlines ($516) and Lufthansa ($781).

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Good to know

Cheapest flight$437
Flight from Des Moines to Prague

FAQs - booking Czech Republic flights

  • How does KAYAK find such low prices on flights from Des Moines to the Czech Republic?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to the Czech Republic.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to the Czech Republic?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to the Czech Republic is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to the Czech Republic?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to the Czech Republic with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to the Czech Republic?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to the Czech Republic up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to the Czech Republic?

    The cheapest time of day to fly to the Czech Republic is generally in the evening, when round-trip flights cost $1,080 on average. Morning departures are around 7% more expensive than evening flights, on average. The most expensive time of day to fly to the Czech Republic is generally in the morning, which is peak travel time and where the average cost of a ticket is $1,157.

Reviews of the top airline flying from Des Moines to the Czech Republic

 
Need help choosing which airline to fly with from Des Moines to the Czech Republic? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9012 reviews
7.3Comfort
6.6Food
7.7Boarding
7.1Entertainment
8.1Crew
Airline reviews

Older aircraft, no meal, only food was for purchase. Not impressed United.

4.0 OkayThomas, Nov 2025SFO - KOA
Read more United Airlines reviews

Older aircraft, no meal, only food was for purchase. Not impressed United.

United needs to step up their game. Delayed flight leaving Seattle, San Francisco. Older aircraft, not very comfortable.

Always wish for more healthy, gluten free options. We have to bring our own.

Having a long layover, I was very appreciative of the ability to stand by for an earlier flight. Other airlines like Delta have refused this to me in the past, just to be mean (because my ticket class wasn't high enough). United went out of their way to help me get to my destination early, which I really appreciated given that it was the third leg of a 24+ hour journey for me.

Other than a way way too cold cabinets for the entire flight, all was great

One bag is incorrect and not acceptable for an international flight. The food was not just good. I won't fly with them again.

Not pleasant trip cross country when the entertainment and WiFi system not working. No entertainment for entirety of route. Staff was rather nonchalant in that they dismissed the problem due to age of plane. It would have been nice to know this up front so I could have come prepared to read or download movies before boarding Coincidentally or not, there was a similar issue with the entertainment system on my previous flight I took on my fist leg of the trip. There are no seat TVs, so you must rely on the app when it works. United can do better. Also, what use it it to pay for boarding group 2 when half of the passengers are in the same line as you?

Plane boarded early a quickly, was mostly full. We left close to on time. And landed early.

My experience on this United Airlines flight was highly uncomfortable, primarily due to two issues: Cabin Temperature: The temperature on the Boeing 737 MAX 8 was unacceptably high, feeling consistently around 80 degrees throughout the flight. This made sleeping impossible and significantly detracted from the experience. Seating Arrangement: Being stuck in a middle seat for a six-and-a-half-hour overnight flight compounded the discomfort. Moving forward, I will always purchase a seat assignment to avoid this situation.

Premium Plus is a really good idea for longer flights

Everything you need to know for your flight from Des Moines to the Czech Republic

Information on your arrival and departure airports

Des Moines (DSM)