$285 Find Cheap Flights from Des Moines to the Czech Republic

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to the Czech Republic departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Des Moines to the Czech Republic Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to the Czech Republic that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to the Czech Republic

Tue, Feb 24 - Tue, Mar 3
American Airlines Logo
3:26 pm - 5:30 pm
DSM
-
PRG
19h 04m2 stops
American Airlines Logo
10:55 am - 11:59 pm
PRG
-
DSM
20h 04m2 stops
$452American Airlines
Mon, Feb 23 - Mon, Mar 2
British Airways Logo
7:44 pm - 10:50 pm
DSM
-
PRG
44h 06m2 stops
British Airways Logo
9:35 pm - 11:40 pm
PRG
-
DSM
33h 05m2 stops
$456British Airways
Sun, Feb 22 - Sun, Mar 1
British Airways Logo
1:38 pm - 6:10 pm
DSM
-
PRG
21h 32m2 stops
British Airways Logo
10:55 am - 11:40 pm
PRG
-
DSM
19h 45m2 stops
$469British Airways
Mon, Feb 23 - Mon, Mar 2
British Airways Logo
1:38 pm - 8:35 pm
DSM
-
PRG
23h 57m2 stops
British Airways Logo
7:00 pm - 11:40 pm
PRG
-
DSM
35h 40m2 stops
$470British Airways
Mon, Feb 23 - Mon, Mar 2
British Airways Logo
1:38 pm - 10:50 pm
DSM
-
PRG
26h 12m2 stops
British Airways Logo
9:35 pm - 11:40 pm
PRG
-
DSM
33h 05m2 stops
$472British Airways
Sun, Feb 22 - Sun, Mar 1
British Airways Logo
1:38 pm - 1:35 pm
DSM
-
PRG
16h 57m2 stops
British Airways Logo
10:55 am - 11:40 pm
PRG
-
DSM
19h 45m2 stops
$475British Airways
Mon, Feb 23 - Mon, Mar 2
American Airlines Logo
3:26 pm - 5:30 pm
DSM
-
PRG
19h 04m2 stops
American Airlines Logo
6:45 am - 6:19 pm
PRG
-
DSM
18h 34m2 stops
$476American Airlines
Sun, Feb 22 - Sun, Mar 1
British Airways Logo
1:38 pm - 6:10 pm
DSM
-
PRG
21h 32m2 stops
British Airways Logo
10:55 am - 11:40 pm
PRG
-
DSM
19h 45m2 stops
$478British Airways
Mon, Feb 23 - Mon, Mar 2
American Airlines Logo
1:38 pm - 8:35 pm
DSM
-
PRG
23h 57m2 stops
American Airlines Logo
11:00 am - 11:40 pm
PRG
-
DSM
19h 40m2 stops
$485American Airlines
Sun, Feb 22 - Sun, Mar 1
British Airways Logo
1:38 pm - 8:45 pm
DSM
-
PRG
24h 07m2 stops
British Airways Logo
10:55 am - 11:40 pm
PRG
-
DSM
19h 45m2 stops
$487British Airways
Booking Insights

KAYAK's insights & trends for Des Moines to the Czech Republic flights

Get data-powered insights and trends into flights from Des Moines to the Czech Republic to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Des Moines and Czech Republic?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Des Moines to the Czech Republic.

There is just one airline that flies from Des Moines to the Czech Republic direct and that is United Airlines. The best round-trip deal found from United Airlines for the route is to Prague (PRG) and costs $597.

Which airlines provide the cheapest flights from Des Moines to the Czech Republic?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to the Czech Republic were found on American Airlines ($452) and British Airways ($456).

Good to know

Cheapest flight$285
Flight from Des Moines to Prague

FAQs - booking Czech Republic flights

  • How does KAYAK find such low prices on flights from Des Moines to the Czech Republic?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to the Czech Republic.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to the Czech Republic?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to the Czech Republic is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to the Czech Republic?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to the Czech Republic with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to the Czech Republic?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to the Czech Republic up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to the Czech Republic

 
Need help choosing which airline to fly with from Des Moines to the Czech Republic? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9145 reviews
7.3Comfort
7.1Entertainment
7.7Boarding
6.6Food
8.1Crew
Airline reviews

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

4.0 OkayWalter, Jan 2026
CLE - SFO
Read more United Airlines reviews

Teeny tiny bathrooms, crew was not realistic about when we'd arrive.

Check-in, boarding and the flight from Phoenix to Houston was quick and easy. The flight from Houston to Shreveport was delayed 5 hours. It was frustrating but I think United handled it the best they could.

Some flight attendants were great others were cranky. Seats were very tight and sitting on an aisle was very hard as the carts and people walking constantly bumped shoulder and arm.

It was great with United overall except for two things. 1) It was a 5-hour flight and we were with kids, so we were asking for extra snacks. They were extremely reticent to dole them out even though there wasn't any meal and the kids were starting to hit their limit towards the end. 2) Baggage didn't arrive until 80 minutes after we landed.

They lost my luggage, so, not happy. The crew was nice but my suitcases never made it, still trying to find out what happened!

The staff was hospitable and professional. The seat had a bit of wear. The winner shade was stuck 1/4 open. I received the best of both worlds. The morning sun was able to come in and blind the screen i was trying to use while at the same time it was too low to look out and enjoy the view. Rather embarrassing for a 1st class ticket.

Perfect flight. Smooth flight. Arrived 20 minutes early at destination. Excellent service.

The flights were on time which was great give. It was holiday travel season and there’d been some weather issues. The only complaint and this is every time with United is the terrible seat design. The head rest is not built for comfort and having my neck bent forward for a cross country trip reminded me while I try not to take United flights as a rule.

I’m so sorry, I can’t remember her name, I believe it was Dimpti. She was stellar, also a mature Asian flight attendant, lots of flowers in her hair, just as amazing! But literally the crew was AWESOME . Only downside is there weren’t any charging outlets. Maybe I needed to ask a flight attendant , but it would’ve been nice to have one easily accessible.

The flight was delayed by two de-icings. The seatbelt did not work correctly. It did not stay tight.

Everything you need to know for your flight from Des Moines to the Czech Republic

Information on your arrival and departure airports