$412 Find Cheap Flights from Des Moines to the Czech Republic

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to the Czech Republic departing on 3/27. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Des Moines to the Czech Republic Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to the Czech Republic that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to the Czech Republic

Wed, Apr 15 - Wed, Apr 22
Multiple Airlines Logo
6:00 am - 6:45 pm
DSM
-
PRG
29h 45m
2 stops
Multiple Airlines Logo
11:35 am - 10:26 am
PRG
-
DSM
29h 51m
2 stops
$512Multiple Airlines
Fri, May 1 - Sun, May 10
British Airways Logo
5:01 pm - 10:50 pm
DSM
-
PRG
22h 49m
2 stops
British Airways Logo
6:50 am - 7:33 pm
PRG
-
DSM
19h 43m
2 stops
$597British Airways
Fri, May 1 - Sun, May 10
United Airlines Logo
6:15 am - 8:55 am
DSM
-
PRG
19h 40m
2 stops
United Airlines Logo
6:10 am - 10:45 pm
PRG
-
DSM
23h 35m
2 stops
$611United Airlines
Wed, Mar 4 - Sun, Mar 8
United Airlines Logo
5:03 pm - 10:25 pm
DSM
-
PRG
22h 22m
2 stops
United Airlines Logo
3:00 pm - 10:30 am
PRG
-
DSM
25h 30m
2 stops
$711United Airlines
Wed, Mar 4 - Sun, Mar 8
United Airlines Logo
5:03 pm - 10:25 pm
DSM
-
PRG
22h 22m
2 stops
United Airlines Logo
6:15 am - 5:08 pm
PRG
-
DSM
17h 53m
2 stops
$713United Airlines
Wed, Mar 4 - Sun, Mar 8
United Airlines Logo
8:00 am - 1:05 pm
DSM
-
PRG
22h 05m
2 stops
United Airlines Logo
1:45 pm - 10:44 pm
PRG
-
DSM
38h 59m
2 stops
$723United Airlines
Sun, Mar 29 - Sun, Apr 5
British Airways Logo
10:04 am - 1:35 pm
DSM
-
PRG
20h 31m
2 stops
British Airways Logo
6:15 pm - 6:19 pm
PRG
-
DSM
31h 04m
2 stops
$796British Airways
Sat, Mar 28 - Sat, Apr 4
United Airlines Logo
6:49 pm - 8:20 pm
DSM
-
PRG
43h 31m
2 stops
United Airlines Logo
1:25 pm - 10:43 pm
PRG
-
DSM
40h 18m
2 stops
$828United Airlines
Sun, Mar 29 - Sun, Apr 5
Multiple Airlines Logo
5:00 am - 6:45 pm
DSM
-
PRG
30h 45m
2 stops
Multiple Airlines Logo
7:30 pm - 6:57 pm
PRG
-
DSM
30h 27m
2 stops
$841Multiple Airlines
Sat, Mar 28 - Sat, Apr 4
Lufthansa Logo
11:26 am - 11:45 am
DSM
-
PRG
18h 19m
2 stops
Lufthansa Logo
6:00 am - 2:28 pm
PRG
-
DSM
15h 28m
2 stops
$866Lufthansa
Booking Insights

KAYAK's insights & trends for Des Moines to the Czech Republic flights

Get data-powered insights and trends into flights from Des Moines to the Czech Republic to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to the Czech Republic?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to the Czech Republic were found on British Airways ($597) and United Airlines ($611).

Find deals

Good to know

Cheapest flight$412
Flight from Des Moines to Prague

FAQs - booking Czech Republic flights

  • How does KAYAK find such low prices on flights from Des Moines to the Czech Republic?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to the Czech Republic.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to the Czech Republic?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to the Czech Republic is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to the Czech Republic?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to the Czech Republic with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to the Czech Republic?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to the Czech Republic up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to the Czech Republic

 
Need help choosing which airline to fly with from Des Moines to the Czech Republic? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9283 reviews
7.3Comfort
7.7Boarding
7.1Entertainment
8.1Crew
6.6Food
Airline reviews

Very disappointing given gate agent behavior. Filed a formal complaint with United.

2.0 MediocreAnnie Caroline, Feb 2026
SFO - LAX
Read more United Airlines reviews

Very disappointing given gate agent behavior. Filed a formal complaint with United.

Do not like the size of the overhead bin. I think staff should monitor the size of suitcases that are being carried on by passengers to ensure they meet the size requirement.

Crew was great (professional, attentive, prompt). Snacks for 4 hrs flight is deplorable.

Flight delayed. WiFi connectivity very poor if not existant. Last minute arrival forced me to run to catch my connection.

Both of my flights arrived early and check in process was smooth

Terrible. No customer service, no food, no drinks on a 6 hour premier economy booking.

Short flight, but no drink/snack service. The flights both going and coming were delayed.

Much better than Spirit. I was please by the easy fast check in and boarding

Check-in and in-flight staff were better than average. The seat was a fair size but too hard and not enough padding. The cushion/pillow provided is poor (thin and seems to be disposable ,it provides no effective cushioning or support). Food was OK-ish but no choice of inflight snacks and no easy place to get drinks other than water (I could ask for juice by intruding into the staff area at the back of the plane) Entertainment was very good actually. Overall better than I expected from a US-based airline (sorry!) but compared to ANA or Singapore it was so-so. (I live in Japan so they are my comparative airlines)

Everything was on time Will use united again for sure

Everything you need to know for your flight from Des Moines to the Czech Republic

Information on your arrival and departure airports

Des Moines (DSM)