$541 Find Cheap Flights from Des Moines to the Czech Republic

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to the Czech Republic departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Des Moines to the Czech Republic Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to the Czech Republic that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to the Czech Republic

Sat, Apr 25 - Fri, May 1
Scandinavian Airlines Logo
11:04 am - 9:40 amDSM-PRG
39h 36m2 stops
Scandinavian Airlines Logo
8:55 pm - 10:24 pmPRG-DSM
32h 29m2 stops
$541Scandinavian Airlines
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Fri, Mar 27 - Tue, Mar 31
United Airlines Logo
3:15 pm - 10:50 amDSM-PRG
13h 35m2 stops
United Airlines Logo
9:10 am - 9:36 pmPRG-DSM
19h 26m2 stops
$656United Airlines
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Fri, May 1 - Sun, May 10
Lufthansa Logo
6:45 pm - 4:05 pmDSM-PRG
14h 20m2 stops
Lufthansa Logo
6:10 am - 9:36 pmPRG-DSM
22h 26m2 stops
$687Lufthansa
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Fri, May 1 - Sun, May 10
Lufthansa Logo
6:45 pm - 4:05 pmDSM-PRG
14h 20m2 stops
Lufthansa Logo
6:10 am - 9:36 pmPRG-DSM
22h 26m2 stops
$688Lufthansa
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Mon, Dec 15 - Mon, Dec 22
Multiple Airlines Logo
10:20 am - 8:25 amDSM-PRG
15h 05m2 stops
Multiple Airlines Logo
2:30 pm - 8:02 pmPRG-DSM
36h 32m2 stops
$815Multiple Airlines
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Mon, Dec 15 - Mon, Dec 22
Multiple Airlines Logo
10:20 am - 8:25 amDSM-PRG
15h 05m2 stops
Multiple Airlines Logo
2:30 pm - 8:02 pmPRG-DSM
36h 32m2 stops
$818Multiple Airlines
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Sat, Apr 25 - Fri, May 1
Air Canada Logo
11:30 am - 12:45 pmDSM-PRG
18h 15m3 stops
Air Canada Logo
9:35 am - 9:36 pmPRG-DSM
19h 01m3 stops
$1,340Air Canada
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Thu, Dec 18 - Thu, Dec 25
KLM Logo
6:33 pm - 5:35 pmDSM-PRG
16h 02m2 stops
KLM Logo
6:00 am - 8:02 pmPRG-DSM
21h 02m2 stops
$1,461KLM
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Thu, Dec 18 - Thu, Dec 25
KLM Logo
6:33 pm - 5:35 pmDSM-PRG
16h 02m2 stops
KLM Logo
6:00 am - 8:02 pmPRG-DSM
21h 02m2 stops
$1,468KLM
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Wed, Dec 17 - Wed, Dec 24
Air Canada Logo
11:35 am - 1:05 pmDSM-PRG
18h 30m3 stops
Air Canada Logo
7:30 am - 9:40 pmPRG-DSM
21h 10m3 stops
$1,726Air Canada
Find Deal
Booking Insights

KAYAK's insights & trends for Des Moines to the Czech Republic flights

Get data-powered insights and trends into flights from Des Moines to the Czech Republic to help you find the cheapest flights, the best time to fly and much more.

Which airlines fly non-stop between Des Moines and Czech Republic?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for round-trip flights from Des Moines to the Czech Republic.

There is just one airline that flies from Des Moines to the Czech Republic direct and that is United Airlines. The best round-trip deal found from United Airlines for the route is to Prague (PRG) and costs $597.

Which airlines provide the cheapest flights from Des Moines to the Czech Republic?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to the Czech Republic were found on Scandinavian Airlines ($541) and United Airlines ($656).

Good to know

Cheapest flight$541
Most popular time to fly and prices are also 17% lower on average.
Flight from Des Moines to Prague

FAQs - booking Czech Republic flights

  • How does KAYAK find such low prices on flights from Des Moines to the Czech Republic?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to the Czech Republic.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to the Czech Republic?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to the Czech Republic is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to the Czech Republic?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to the Czech Republic with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to the Czech Republic?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to the Czech Republic up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to the Czech Republic?

    The cheapest time of day to fly to the Czech Republic is generally in the evening, when round-trip flights cost $1,080 on average. Morning departures are around 7% more expensive than evening flights, on average. The most expensive time of day to fly to the Czech Republic is generally in the morning, which is peak travel time and where the average cost of a ticket is $1,157.

Reviews of the top airline flying from Des Moines to the Czech Republic

 
Need help choosing which airline to fly with from Des Moines to the Czech Republic? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9002 reviews
7.7Boarding
6.6Food
8.1Crew
7.1Entertainment
7.3Comfort
Airline reviews

Premium Plus is a really good idea for longer flights

10.0 ExcellentAnton, Nov 2025SFO - EWR
Read more United Airlines reviews

Premium Plus is a really good idea for longer flights

7 hours delayed due to operational issues on United’s end. Basically laziness.

Short flight but an "eager to help" crew made the journey more enjoyable!

Flight was delayed only slightly before takeoff due to traffic control. However, the flight arrived early to ORD. Good flight. United has been very reliable for me.

The person I bought the ticket for didn’t make the flight.

Lately I like the planes have been exceptionally filthy. There’s lines of dust and dirt all across the ceiling in the vents, and the cracks in between the seats are literally full of food. It’s definitely not the quality of service that I was used to with United. I’m also very disappointed with the Wi-Fi! All I wanna do is knock out a few work jobs while I’m trapped in my seat And it spools so bad. They did provide me with a refund, but the process of getting that refund is so complicated. It’s unfortunate.

Another delayed flight. When the delays exceed the duration of the flight, it’s a problem.

Excellent flight. Smooth, efficient boarding. Quick flight. Arrived early at STL.

After boarding the plane in Chicago, the passengers were told that there was a technical problem with the plane. Passengers remained on the plane as they tried to fix the problem. After what was probably an hour passengers were told that there was a need to change planes as the problem was not solved. Passengers disembarked and boarded another plane. After taxing to the runway and waiting for takeoff, passengers were told that owing to the thunderstorm the flight was unable to take off but would try and reroute. After some time passengers were told there wasn't enough fuel for the new route and the plane had to return to the gate for additional fuel. after another log delay the flight got underway. On the plane there was food, drinks, ice or entertainment. We were a glass of water, which appeared rationed. Flight arrived about 5 hours late. The pilot was fantastic and communicated with the passengers throughout the ordeal.

Same as last comment. Food sucks. Quality. Not surprising most people have no clue about nourishment Clearly

Everything you need to know for your flight from Des Moines to the Czech Republic

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