$505 Find Cheap Flights from Des Moines to the Czech Republic

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to the Czech Republic departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Book Cheap Des Moines to the Czech Republic Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to the Czech Republic that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to the Czech Republic

Wed, Mar 18 - Wed, Mar 25
Air France Logo
11:33 am - 11:40 am
DSM
-
PRG
18h 07m
2 stops
Air France Logo
6:30 am - 4:54 pm
PRG
-
DSM
16h 24m
2 stops
$505Air France
Wed, Mar 4 - Sun, Mar 8
United Airlines Logo
5:03 pm - 4:05 pm
DSM
-
PRG
16h 02m
2 stops
United Airlines Logo
3:00 pm - 2:24 pm
PRG
-
DSM
29h 24m
2 stops
$512United Airlines
Wed, Mar 18 - Wed, Mar 25
Delta Logo
11:33 am - 5:05 pm
DSM
-
PRG
23h 32m
2 stops
Delta Logo
11:35 am - 9:46 am
PRG
-
DSM
28h 11m
2 stops
$516Delta
Thu, Mar 19 - Thu, Mar 26
Lufthansa Logo
7:15 am - 1:05 pm
DSM
-
PRG
23h 50m
2 stops
Lufthansa Logo
6:15 am - 9:40 pm
PRG
-
DSM
21h 25m
2 stops
$529Lufthansa
Fri, May 1 - Sun, May 10
British Airways Logo
5:01 pm - 4:50 pm
DSM
-
PRG
16h 49m
2 stops
British Airways Logo
10:40 am - 11:49 pm
PRG
-
DSM
20h 09m
2 stops
$598British Airways
Thu, Mar 19 - Thu, Mar 26
Delta Logo
6:15 am - 10:50 am
DSM
-
PRG
22h 35m
2 stops
Delta Logo
6:30 am - 8:45 pm
PRG
-
DSM
20h 15m
2 stops
$622Delta
Fri, Mar 20 - Fri, Mar 27
Air Canada Logo
2:59 pm - 10:25 pm
DSM
-
PRG
25h 26m
2 stops
Air Canada Logo
6:50 am - 9:40 pm
PRG
-
DSM
20h 50m
2 stops
$701Air Canada
Thu, Mar 19 - Thu, Mar 26
Delta Logo
10:51 am - 5:35 pm
DSM
-
PRG
24h 44m
2 stops
Delta Logo
6:30 am - 8:45 pm
PRG
-
DSM
20h 15m
2 stops
$757Delta
Thu, Mar 19 - Thu, Mar 26
Multiple Airlines Logo
5:47 pm - 1:45 pm
DSM
-
PRG
13h 58m
2 stops
Multiple Airlines Logo
8:55 am - 8:45 pm
PRG
-
DSM
17h 50m
2 stops
$774Multiple Airlines
Thu, Jul 30 - Thu, Aug 13
American Airlines Logo
1:43 pm - 8:15 am
DSM
-
PRG
11h 32m
1 stop
American Airlines Logo
10:15 am - 11:55 pm
PRG
-
DSM
20h 40m
1 stop
$850American Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to the Czech Republic flights

Get data-powered insights and trends into flights from Des Moines to the Czech Republic to help you find the cheapest flights, the best time to fly and much more.

Which airlines provide the cheapest flights from Des Moines to the Czech Republic?

The cheapest round-trip price for the route for each airline clicked by KAYAK users in the last 72 hours.

In the past 3 days, the cheapest round-trip tickets from Des Moines to the Czech Republic were found on United Airlines ($512) and Delta ($516).

Good to know

Cheapest flight$505
Flight from Des Moines to Prague

FAQs - booking Czech Republic flights

  • How does KAYAK find such low prices on flights from Des Moines to the Czech Republic?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to the Czech Republic.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to the Czech Republic?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Des Moines to the Czech Republic is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to the Czech Republic?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Des Moines to the Czech Republic with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to the Czech Republic?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Des Moines to the Czech Republic up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airline flying from Des Moines to the Czech Republic

 
Need help choosing which airline to fly with from Des Moines to the Czech Republic? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.4
United AirlinesOverall score based on 9236 reviews
6.6Food
7.1Entertainment
8.1Crew
7.7Boarding
7.3Comfort
Airline reviews

Not being stranded in Chicago for her airport to 11:30 tomorrow morning the 3rd

2.0 MediocreRonald, Feb 2026
ORD - BWI
Read more United Airlines reviews

Not being stranded in Chicago for her airport to 11:30 tomorrow morning the 3rd

the whole trip was smooth, and as comfortable as flying is these days. flight crew was friendly and very courteous and helpful.

The attendant on board was amazing. She should be doing business/first international long haul.

Although our flight was delayed the overall boarding process was very smooth and the crew was accommodating.

I was fully checked in the prior night and i was unchecked and then didn’t have a seat when I boarded. Instead of an aisle seat, I was out in the middle seat of the very last row of the plane.

In overall it was a good experience, the only down point was that the entertainment screen was working properly.

HORRIBLE, my initial flight was cancelled, they made me pay $200 extra dollars and that got cancelled as well! After 6 cancellations I decided to get a refund because I needed to get home to my babies. Out of $1000+ dollars they offered me only $40 in refund! Totally unacceptable! The flight that they cancelled I was able to fly it on another airline. I had to spend $400 on one way tickets just to get home! I’m still getting the runaround.

First class ticket gets you a choice of chips or nuts. . Just like economy Southwest. Also no screen in the seats. This is first class???!

Seated dude next to me even though lots of empty rows. But main thing was we sat on the tarmac after landing for 30 minutes because of, in the words of the dude who sat next to me, “operational incompetence”. We got changing directions about where to pick up gate checked bags. Pilot and flight attendant were awesome though.

The food was terrible this time. Otherwise pleasant, quiet, on-time.

Everything you need to know for your flight from Des Moines to the Czech Republic

Information on your arrival and departure airports