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DSM - PTY

$133 Find cheap flights from Des Moines to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Panama City departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sun 6/16
Sun 6/23

Search hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Panama City, as well as popular online travel agencies
In the last 7 days travelers have searched 42,211,976 times on KAYAK, and here is why:

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Cheap flight deals from Des Moines to Panama City (DSM-PTY)

Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
6:37 pm - 12:55 pmDSM-PTY
18h 18m1 stop
2:20 pm - 10:24 pmPTY-DSM
8h 04m1 stop
$330Delta
Find Deal
Mon, Sep 23 - Thu, Sep 26
4:20 pm - 12:33 pmDSM-PTY
20h 13m2 stops
1:55 pm - 9:06 amPTY-DSM
19h 11m2 stops
$333American Airlines
Find Deal
Sat, Sep 14 - Sat, Sep 21
6:37 pm - 12:55 pmDSM-PTY
18h 18m1 stop
2:20 pm - 11:27 amPTY-DSM
21h 07m2 stops
$334Delta
Find Deal
Mon, Sep 23 - Thu, Sep 26
3:00 pm - 6:37 pmDSM-PTY
27h 37m1 stop
9:45 am - 10:41 amPTY-DSM
24h 56m2 stops
$407United Airlines
Find Deal
Sat, Sep 14 - Sat, Sep 21
6:05 am - 6:37 pmDSM-PTY
12h 32m1 stop
10:00 am - 10:27 amPTY-DSM
24h 27m2 stops
$439United Airlines
Find Deal
Thu, Jun 13 - Thu, Jun 20
6:05 am - 6:37 pmDSM-PTY
12h 32m1 stop
3:40 pm - 2:20 pmPTY-DSM
22h 40m1 stop
$445United Airlines
Find Deal
Thu, Oct 10 - Mon, Oct 14
6:00 am - 6:37 pmDSM-PTY
12h 37m2 stops
3:40 pm - 10:28 amPTY-DSM
18h 48m2 stops
$522United Airlines
Find Deal
Thu, Oct 10 - Mon, Oct 14
6:41 pm - 4:06 pmDSM-PTY
21h 25m2 stops
10:00 am - 10:27 amPTY-DSM
24h 27m2 stops
$544United Airlines
Find Deal
Thu, Jun 13 - Thu, Jun 20
6:05 am - 4:06 pmDSM-PTY
10h 01m1 stop
7:55 am - 10:15 pmPTY-DSM
14h 20m1 stop
$1,020United Airlines
Find Deal
Thu, Jun 13 - Thu, Jun 20
6:55 am - 12:33 pmDSM-PTY
29h 38m1 stop
1:55 pm - 11:45 pmPTY-DSM
9h 50m1 stop
$1,022American Airlines
Find Deal
Sat, Sep 14 - Sat, Sep 21

Flights from Des Moines to Panama City - Travel Insights & Trends

Get data-powered insights and trends into flights from Des Moines to Panama City to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights from Des Moines to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Des Moines to Panama City is May, where tickets cost $396 on average. On the other hand, the most expensive months are December and June, where the average cost of tickets is $1,074 and $835 respectively.

Which airlines provide the cheapest flights from Des Moines to Panama City?

The cheapest price for the route for each airline clicked by KAYAK users in the last 72 hours.
The best deals for a one-way ticket found by KAYAK users over the last 3 days were on United Airlines ($133) and Delta ($138). The cheapest round-trip tickets were found on Delta ($330) and American Airlines ($333).

Good to know

Low season

July

High season

January

Cheapest flight

$133
Best time to beat the crowds but there is an average 22% increase in price.
Most popular time to fly and prices are also 12% lower on average.
Flight from Des Moines to Panama City

When to book flights from Des Moines to Panama City

Are your dates flexible? Find out the best times to travel from Des Moines to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Panama City

  • What is the cheapest flight from Des Moines to Panama City?

    In the last 3 days, the lowest price for a flight from Des Moines to Panama City was $133 for a one-way ticket and $330 for a round-trip.

  • Do I need a passport to fly between Des Moines and Panama City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Des Moines and on arrival in Panama City.

  • Which aircraft models fly most regularly from Des Moines to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Panama City?

    Star Alliance, SkyTeam, and oneworld are the airline alliances operating flights between Des Moines and Panama City, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Panama City, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Panama City are Delta and United Airlines. With an average price for the route of $539 and an overall rating of 8.0, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $466 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top 3 airlines serving from Des Moines to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10673 reviews
7.9Comfort
7.4Food
8.0Entertainment
8.2Boarding
8.6Crew
Airline reviews

The Flight crew didn’t serve us until about 1.5 hours into the flight because of turbulence but after it ended it was fine to move around. They served us water only and snacks and then NEVER, NOT ONE TIME came through to collect trash until right before landing about 1.5 hours later. There was absolutely no need for that. They crew was just standing around talking and visiting with each other and really never tried to see if we might want something besides water or even try to come pick up trash. This is VERY unusual for a Delta flight but it was not what I would have expected for a 4 hour flight.

6.0 GoodLane, May 2024MEM - LAX
Read more about Delta reviews

The Flight crew didn’t serve us until about 1.5 hours into the flight because of turbulence but after it ended it was fine to move around. They served us water only and snacks and then NEVER, NOT ONE TIME came through to collect trash until right before landing about 1.5 hours later. There was absolutely no need for that. They crew was just standing around talking and visiting with each other and really never tried to see if we might want something besides water or even try to come pick up trash. This is VERY unusual for a Delta flight but it was not what I would have expected for a 4 hour flight.

The 1st class male crew member was very pleasant - the short female with round glasses , maybe in 50’s had no personality- never spoke when delivering my food, drink, & never smiled the whole trip! In fact looked annoyed when the boarding proses was happening- I would never hire this woman - unfriendly . Have never dealt with a crew member like her-

5-hour delay due to storms in Tanoa and airspace restricted by Miami traffic controllers.

A regional sized plane was used for a cross country flight with no overhead bin space. I had to "pink check" my laptop and my medications. I was NOT pleased!!!!

Absolutely nothing flight was cancelled and delayed for 2 days. Barely a heads up I want a full refund

The plane from SNA wouldn’t start after 5 tries. The team gave me an option of flying direct from LAX and giving me a Lyft ride there! Perfect!

Best airline! Always friendly and welcoming. Skyclub was great and loved the fast free wifi on board. I also love that you can pre-order your meal on the app!

Atlanta boarding crew at gate were filled with arrogance and were disrespectful. In flight crew showed indifference to the needs of passengers. This is about the flight from ATL to BDL.

The plane was FREEZING SEATS UNCOMFORTABLE Otherwise smooth Thank you

Boarding was chaotic. I didn’t finish dinner because I went to bed early. Breakfast omelet was overcooked and tasteless but croissant was better than usual. Plane was dirty—crumbs in every seam and lavatory was poorly maintained (paint peeling, etc.) and toilet paper had not been refreshed before takeoff. No cubby for storage in first and seat was narrow.

Standard flight experience, but there is only power at the seat to row 20 on the aircraft, on my initial check in it did not say that was the case

Not a fan of the diagonal partially enclosed business class seats or how they have to be converted to beds manually by crew. I prefer more isolation and user control for switching to lie flat.

No lounge access with “United First” ticket. False alarm about late flight, jeopardizing connection. Wrong meal. Loose power socket would not hold plug, could not charge device. In-flight access to text messaging did not work. Toilet seat on plane would not stay up.

We ended up with seats in the very back. So they did not recline. Have no idea why, we reserved and checked in very early. The isles were very narrow and the seats had very little leg room. But they did give us water, and a snack.

Energetic crew - flight full of swiftied going to Taylor's opening show in Paris! Long lines for bathroom made out kind of suck though

Check in etc was very good. As for on the plane, it was like flying in a freezer. It was so cold, i have flown for years and never been so cold on a plane. Staff on board said its always cold when flying which is a load of rubbish. They wouldnt put any heating on and now i have the flu because of this .

I’ve had a couple flights this week on United that were delayed by an hour or more

Flight was delayed 2.5 hours - a big deal on an overnight when you plan to sleep.

I feel like they have upgraded the app since I last flew United and I found it to be super helpful. I had stopped flying United unless absolutely necessary and my experience on this trip indicates they have been working hard to improve their services.

Surprisingly easy! I was hesitant to try this, but the cost swayed me. I actually felt like I had less stress than all the taxiing and possible delays that occur with short regional flights where you spend less time in the air than getting to and from the plane..

The flight was short. However, my bag was delayed and was put on another flight.

Flight attendant was incredible. Very efficient, friendly and pleasant. Patricia was one of the best I have ever seen. Please give her a big raise!

Delayed multiple times. Boarding was ok but getting off the aircraft was a mess. So disorganized with staff trying to help the elderly but completely blocking path for anyone else to move. Bathroom was disgusting, probably caused by one of the customers but staff couldn't care less to help clean it. No one wanted to use it since the floor was completely soaked so everyone just lined up the other restroom while the staff just chit chat with each other while looking at us.

LIT to DFW - 3 hours late; the entire plane had been boarded before they told us there was a delay due to a weather-related ground stop in Dallas. DFW to MAY - 2+ hours late due to A/C needing to be repaired after everyone had boarded, then when we finally reach the runway, the First Officer timed out and we had to taxi all the way back to the gate and wait for a new one. I arrived in New Orleans 5+ hours later than I should have. Return flights were completely cancelled; rebooked through the app to fly through CLT instead of DFW. MSY to CLT had no issues, but CLT to LIT was delayed 1.25 hrs because flight attendants had not arrived to the airport yet. At least they didn’t make us all sit on the plane to wait for them. I should have driven.

Tray table was filthy when I sat down. I needed to have someone come clean it because there was food and stains on it WiFi didn’t work after paying for in flight WiFi Food was terrible and was not filling at all Chicken was rubbery Flight attendant had an attitude, interrupted me and wasn’t able to answer basic questions about the food selection such as “does the chicken have red sauce in it”. If your flight attendants are not going to know what is in the meals so we can make an educated decision based on dietary restrictions, they shouldn’t be on the plane. My 1.5 year old niece was sleeping and dropped her binkie. I went on the ground under the chairs looking for it. It was at that time that she came up to me as I’m CLEARLY on all 4s with a flashlight and said “I need to get by”. I said one moment please I’m getting something from under the seat (while my head was literally under the seat). Her reply was “no you need to move now” and proceeded to almost push me out of the way. I looked up and all I saw was her toes under my eyes. When I looked in front of me, her private parts were inches away from my face. I then made a comment “you couldn’t waited 2 seconds?” and her response was, “no I need to use the bathroom”. I understand that and would never want to be the reason someone couldn’t get to the bathroom but I was under the seat. She could’ve gone around the other way instead of harassing me, basically placing her private parts on my head and borderline pushing me out of the way. You don’t pay (especially this much) for this deplorable experience. This was by far the worst experience I have ever had on American. I will be absolutely thinking twice and thrice about flying American Airlines again. I would rather pay more to fly delta because at least I know their WiFi will work and their flight attendants won’t have a terrible attitude for no reason, nor will they act the way this woman did. Unacceptable.

Tray table was filthy when I sat down. I needed to have someone come clean it because there was food and stains on it WiFi didn’t work after paying for in-flight WiFi. Food was terrible and was not filling at all Chicken was rubbery Flight attendant had an attitude, interrupted me and wasn’t able to answer basic questions about the food selection such as “does the chicken have red sauce in it”. If your flight attendants are not going to know what is in the meals so we can make an educated decision based on dietary restrictions, they shouldn’t be on the plane. My 1.5 year old niece was sleeping and dropped her binkie. I went on the ground under the chairs looking for it. It was at that time that she came up to me as I’m CLEARLY on all 4s with a flashlight and said “I need to get by”. I said one moment please I’m getting something from under the seat (while my head was literally under the seat). Her reply was “no you need to move now” and proceeded to almost push me out of the way. I looked up and all I saw was her toes under my eyes. When I looked in front of me, her private parts were inches away from my face. I then made a comment “you couldn’t waited 2 seconds?” and her response was, “no I need to use the bathroom”. I understand that and would never want to be the reason someone couldn’t get to the bathroom but I was under the seat. She could’ve gone around the other way instead of harassing me, basically placing her private parts on my head and borderline pushing me out of the way. You don’t pay that much for this deplorable experience. This was by far the worst experience I have ever had on American. I will be absolutely thinking twice and thrice about flying American Airlines again. I would rather pay more to fly delta because at least I know their WiFi will work and their flight attendants won’t have a shitty attitude for no reason, nor will they act the way this woman did. Unacceptable.

Liked - nothing. Disliked - delayed 35+ min sitting on the plane. Caused me to miss my connection in Charlotte. American Airlines is the worst US Air Carrier company with atrocious customer service.

Worst situation ever! I booked my tickets for this trip on Alaska Airlines. I guess AA is a partner and we flew nonstop from Eugene to PHX on an AA jet. I had to pay for luggage from PHX to EUG. And this was an Alaska Airlines reservation paid for with Alaska airlines credit card! Got to the PHX airport and was not able to check bags because of some weird issue with the AA software. My reservation had to be the-entered by the agent. I will never pick another American Airlines flight on the Alaska Airlines website. While on vacation, I tried to upgrade our seats for the trip home. The request just buffered and never went through. I tried four times and was charged four times on my credit card. The card was charged but the seats were never changed. What a wreck!

Left from gate 30 minutes before flight. Never been late to a flight ever. It says 15 minutes before explicitly on the ticket.

I like the boarding process, it was fast. The seat doesn’t have a TV for a long flight and food wasn’t served, just snacks.

Book cheap flights from Des Moines to Panama City

Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Des Moines to Panama City found on KAYAK in the last 72 hours.
5/22Wed
1 stopUnited Airlines
12h 33mDSM-PTY
$133
7/26Fri
2 stopsDelta
25h 58mDSM-PTY
$138
6/19Wed
1 stopUnited Airlines
25h 12mDSM-PTY
$145
6/15Sat
2 stopsUnited Airlines
16h 34mDSM-PTY
$173
7/25Thu
2 stopsDelta
26h 36mDSM-PTY
$178
7/25Thu
1 stopUnited Airlines
25h 07mDSM-PTY
$186
7/24Wed
2 stopsUnited Airlines
10h 37mDSM-PTY
$198
7/28Sun
2 stopsAmerican Airlines
18h 49mDSM-PTY
$223
6/20Thu
2 stopsUnited Airlines
19h 38mDSM-PTY
$238
6/16Sun
2 stopsAmerican Airlines
20h 07mDSM-PTY
$321

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Des Moines - Panama City Flights

Departure:

Des Moines (undefined)United States

Destination:

Panama City (PTY)Panama

Cabin classes: