DSM - PTY

$209 Find Cheap Flights from Des Moines to Panama City

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Des Moines to Panama City departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

KAYAK searches hundreds of travel sites at once for deals on flights to Panama City

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Panama City, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Des Moines to Panama City, as well as popular online travel agencies
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Everything you should know

Cheapest round-trip
$483
Typical prices: $518-$952
United Airlines
dt. 2/24dv. 3/6
DSM - PTY • 1 stop
Cheapest one-way
$209
United Airlines
dl. 3/16
DSM - PTY • 2 stops
Top airlines
United Airlines
Cheapest • from $483 (round-trip)
Delta
Best reviews • 7.9 score
Airline reviews
Airline reviews
+1
+1
Airline reviews
Airline reviews
+1
When to travel
September
Cheapest • 23% price drop
February
Most popular
Good to know
Good to know
+1
+1
Good to know
Good to know
+1
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KAYAK searches 100s of sites at once to find you the best travel deals.
We hope you love your trip to Panama City!
Flight Deals
Booking Insights
Flight Deals

Cheap Flights from Des Moines to Panama City (DSM-PTY)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Des Moines to Panama City that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Des Moines to Panama City

dt., febr. 24 - dv., març 6
United Airlines Logo
7:52 am - 5:07 pm
DSM
-
PTY
8h 15m
1 stop
United Airlines Logo
8:55 am - 10:27 pm
PTY
-
DSM
14h 32m
1 stop
$483United Airlines
dt., febr. 24 - dv., març 6
United Airlines Logo
7:52 am - 7:38 pm
DSM
-
PTY
10h 46m
1 stop
United Airlines Logo
11:55 pm - 2:32 pm
PTY
-
DSM
15h 37m
2 stops
$487United Airlines
dl., febr. 23 - dj., febr. 26
United Airlines Logo
7:52 am - 5:07 pm
DSM
-
PTY
8h 15m
1 stop
United Airlines Logo
4:41 pm - 10:20 pm
PTY
-
DSM
30h 39m
1 stop
$492United Airlines
dl., febr. 23 - dj., febr. 26
United Airlines Logo
3:24 pm - 2:45 pm
DSM
-
PTY
22h 21m
2 stops
United Airlines Logo
4:41 pm - 10:20 pm
PTY
-
DSM
30h 39m
1 stop
$497United Airlines
dj., febr. 26 - ds., març 7
United Airlines Logo
7:52 am - 5:07 pm
DSM
-
PTY
8h 15m
1 stop
United Airlines Logo
4:41 pm - 1:32 pm
PTY
-
DSM
21h 51m
2 stops
$519United Airlines
dj., març 19 - dj., març 26
United Airlines Logo
6:49 pm - 7:02 pm
DSM
-
PTY
24h 13m
2 stops
United Airlines Logo
3:41 pm - 2:24 pm
PTY
-
DSM
22h 43m
2 stops
$535United Airlines
dv., març 20 - dv., març 27
United Airlines Logo
7:15 am - 6:38 pm
DSM
-
PTY
11h 23m
1 stop
United Airlines Logo
3:41 pm - 1:23 pm
PTY
-
DSM
21h 42m
2 stops
$551United Airlines
dj., març 19 - dj., març 26
United Airlines Logo
6:49 pm - 7:02 pm
DSM
-
PTY
24h 13m
2 stops
United Airlines Logo
7:55 am - 10:44 pm
PTY
-
DSM
14h 49m
1 stop
$567United Airlines
dj., març 5 - dl., març 9
American Airlines Logo
7:44 pm - 3:15 pm
DSM
-
PTY
18h 31m
2 stops
American Airlines Logo
3:10 pm - 1:05 pm
PTY
-
DSM
21h 55m
2 stops
$576American Airlines
dc., abr. 22 - dg., abr. 26
United Airlines Logo
8:20 am - 4:12 pm
DSM
-
PTY
7h 52m
1 stop
United Airlines Logo
7:55 am - 10:43 pm
PTY
-
DSM
14h 48m
1 stop
$627United Airlines
Booking Insights

KAYAK's insights & trends for Des Moines to Panama City flights

Get data-powered insights and trends into flights from Des Moines to Panama City to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Des Moines to Panama City?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Des Moines to Panama City, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Des Moines to Panama City is September, where tickets cost $441 (return) on average. On the other hand, the most expensive months are December and March, where the average cost of round-trip tickets is $1,033 and $861 respectively.

Good to know

Low seasonJune
Cheapest flight$209
Best time to beat the crowds with an average 14% drop in price.
Most popular time to fly and prices are also 20% lower on average.
Flight from Des Moines to Panama City

When to book flights from Des Moines to Panama City

Are your dates flexible? Find out the best times to travel from Des Moines to Panama City based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Des Moines to Panama City

  • What is the cheapest flight from Des Moines to Panama City?

    In the last 3 days, the lowest price for a flight from Des Moines to Panama City was $209 for a one-way ticket and $483 for a round-trip.

  • Do I need a passport to fly between Des Moines and Panama City?

    Yes, you'll most likely have to show a valid passport before boarding the plane in Des Moines and on arrival in Panama City.

  • Which aircraft models fly most regularly from Des Moines to Panama City?

    We unfortunately don’t have that data for this specific route.

  • Which airline alliances offer flights from Des Moines to Panama City?

    SkyTeam, and Star Alliance are the airline alliances operating flights between Des Moines and Panama City, with SkyTeam being the most commonly used for this route.

  • Which is the best airline for flights from Des Moines to Panama City, Delta or United Airlines?

    The two airlines most popular with KAYAK users for flights from Des Moines to Panama City are Delta and United Airlines. With an average price for the route of $557 and an overall rating of 7.9, Delta is the most popular choice. United Airlines is also a great choice for the route, with an average price of $481 and an overall rating of 7.4.

  • How does KAYAK find such low prices on flights from Des Moines to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Des Moines to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Des Moines to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Des Moines is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Des Moines to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Des Moines with another airline. Booking your flights between Des Moines and PTY can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Des Moines to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Des Moines up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top airlines flying from Des Moines to Panama City

 
See real verified KAYAK customer reviews for airlines flying from Des Moines to Panama City. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Des Moines to Panama City? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8138 reviews
8.1Boarding
7.2Food
7.9Comfort
8.5Crew
7.8Entertainment
Airline reviews

I was given middle seat on this flight and prior Boston to Seoul flight That is a problem for long flights, Kayak system did not give me a change to select my seats and assigned me middle seats regardless of my elevated status in Delta. This needs immediate attention.

2.0 MediocreAlparda, Feb 2026
BOS - ICN
Read more Delta reviews

I was given middle seat on this flight and prior Boston to Seoul flight That is a problem for long flights, Kayak system did not give me a change to select my seats and assigned me middle seats regardless of my elevated status in Delta. This needs immediate attention.

I didn't take this flight. I changed the flight. Why am I getting surveys and notifications on flights that I change. Seems like a defect with Kayak.

Delta One is extraordinary. I fly business when somebody hires me. I just wonder why there is such a chasm between business class and the insanely inhumane and nonsensical coach. The seats are not large enough to fit even my tiny wife. We fly 10% of what we did because we don’t want to pay 5-10 k but for $400 it’s unbearable. It seems like the accountants took over and made stupid decisions. Screw in 20 extra seats and make it so unbearable that people fly 90% less. Just put the damn price up and put some proper chairs in. But business, yay.

Timing, quality of service, promptness and courtesy of the staff

It was last minute due to weather - considering - it was amazing! Good smiles, friendly staff and they were making sure we knew what was going on when and where.

delta last minute gave me a boarding pass for a different flight with no confirmation that they were changing it

The flight was comfortable and uneventful, which is what I desire

The service from the flight attendants were of supreme quality. They greeted and treated everyone with a wide smile. This is totally absent nowadays. Kudos to them!!!!

Excellent flight and got us around tough weather. Only issue was seat TV did not work and crew tried to reboot.

Very large passenger too space from my own seat. Arm board couldn’t be lowered because of his size. It wads very uncomfortable trip, as the flight was full couldn’t move anywhere having back pain because of the position in which I was the entire flight.

the whole trip was smooth, and as comfortable as flying is these days. flight crew was friendly and very courteous and helpful.

The attendant on board was amazing. She should be doing business/first international long haul.

Although our flight was delayed the overall boarding process was very smooth and the crew was accommodating.

I was fully checked in the prior night and i was unchecked and then didn’t have a seat when I boarded. Instead of an aisle seat, I was out in the middle seat of the very last row of the plane.

In overall it was a good experience, the only down point was that the entertainment screen was working properly.

HORRIBLE, my initial flight was cancelled, they made me pay $200 extra dollars and that got cancelled as well! After 6 cancellations I decided to get a refund because I needed to get home to my babies. Out of $1000+ dollars they offered me only $40 in refund! Totally unacceptable! The flight that they cancelled I was able to fly it on another airline. I had to spend $400 on one way tickets just to get home! I’m still getting the runaround.

First class ticket gets you a choice of chips or nuts. . Just like economy Southwest. Also no screen in the seats. This is first class???!

Seated dude next to me even though lots of empty rows. But main thing was we sat on the tarmac after landing for 30 minutes because of, in the words of the dude who sat next to me, “operational incompetence”. We got changing directions about where to pick up gate checked bags. Pilot and flight attendant were awesome though.

The food was terrible this time. Otherwise pleasant, quiet, on-time.

It was a pretty standard flight... until the almost hour and a half spent on the taxi way. I get that the weather has been poor but the delay had nothing to do with the weather and more to do with a plane with several issues tying up the gate. I get that that happens from time to time but this has been EVERY flight I've been on for the past 5 years and I fly 3 to 5 times a year. This isn't just United... it's American, it's Delta. It's an issue with the entire industry. I work for UPS and packages on a cargo plane get better service than people do these days. Anymore I HATE flying.

Everything you need to know for your flight from Des Moines to Panama City

Information on your arrival and departure airports