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Find cheap flights from Greenville to South America from $311

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to South America departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Thu 5/30
Thu 6/6

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Best South America Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

Lima
Lima1 stop$697
Bogotá
Bogotá1 stop$404
Santiago
Santiago2 stops$922
Quito
Quito1 stop$587
Cali
Cali2 stops$550
Pereira
Pereira2 stops$506

Good to know

Low season

October

High season

June

Cheapest flight

$311
Best time to beat the crowds with an average 21% drop in price.
Most popular time to fly and prices are also 4% lower on average.
Flight from Greenville to Medellín

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Greenville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to South America from Greenville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to South America with an airline and back to Greenville with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to South America from Greenville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to South America

  • Morning departure is around 17% cheaper than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 3 airlines serving from Greenville to South America

 
Need help choosing which airline to fly with from Greenville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10895 reviews
7.4Food
8.6Crew
8.0Entertainment
8.2Boarding
7.9Comfort
Airline reviews

Delayed due to an ill passenger after loading. Not preventable on Delta's part. Was in first class. The seats are becoming worn and detaching from their velcro attachments. Only got snacks on flight. The attendant was not the friendliest.

6.0 GoodJames, Apr 2024TPA - RDU
Read more about Delta reviews

Delayed due to an ill passenger after loading. Not preventable on Delta's part. Was in first class. The seats are becoming worn and detaching from their velcro attachments. Only got snacks on flight. The attendant was not the friendliest.

I would fly again the whole experience was great. The only feed back I can give that they don't do that American Airlines does is the crew there is more humorous with boarding and thank their passengers. It makes it more fun to fly with them. I would however fly Delta again.

Big plane, long flight, absolutely no leg room and basically non existent air! I am 5”4’ and always travel Main Cabin, I was miserable on this plane and could barely move when we arrived in Cabo due to the cramped leg area!

From Atlanta to Cabo I would have hoped on a plane that size I would have been able to breathe and wiggle my feet a little! The leg room in that plane is non existent and I am only 5”4’. And the air vent either wasn’t working very well or just could not blow air from the ceiling to the seat area as I was suffocating through the entire flight! And please don’t say I would have been more comfortable in first class because I cannot afford those rates and have always travelled Main Cabin without issues !

The pilots were good. Disappointing when planes don't have electrical ports

I liked the piloting of the aircraft. Very disappointed about lack of electrical ports. Also, although a short flight. there was enough time to hand out snacks to comfort + seats as was done for first class.

I had a wonderful experience flying with delta. The gentleman taking care of us on our flight was so nice, accommodating, and attentive. He always was smiling and giving pins to the kids which made me smile. The flight was quick too and without turbulence. Thank you for the great flying experience.

Delta is one of the best airlines I have flown

Made the Atlanta to Pittsburgh trip many times, with Delta no issues

I always fly with Delta. My friends tell me their horror stories of flying with other airlines. I just smile and say, “You should fly Delta”

Do not like the feeling of being in the basic economy. Everyone should feel good no matter what.

All flights were on time and boarding was issue free

Terrible! The plane was old and you are required to connect your own device to their Wi-Fi rather than have entertainment options in the back of the seat in front of you. The Wi-Fi went out during the flight and there was only one plug for the devices every two seats. Three out of five surrounding my family did not work. The seats and spaces under them were so small I could not fit my backpack, which I’ve always brought on flights and fit before no problem. The crew were unpleasant and patronizing.

Great! The plane was decently sized and comfortable. The staff was nice and there was great in flight entertainment

Food was terrible Not many options Stewards dont care Delay

Water service would be great. The way they board is terrible. Slow passengers first😂😂 They need to smart up a bit

Our original business class flight was cancelled so we not only downgraded but we were also spread out across the plane not sitting together in separate middle seats. My poor kids were scared and couldn’t see me on the flight and the crew wasn’t sensitive to the situation and what the airlines did to us. Very dissatisfied with United airlines.

Crew were fine, drinks and snacks were as well but we were delayed for around 2 hrs which made our entry into Mexico delayed as well with the influx of arrivals at the same time. Sort of wasted our first day of vacation. We left Pittsburgh at 630am and did not arrive in Mexico until late dinner time.

The ride was good but no food ot entertainment hence, it was just over an hour flight.

There was a group of school age passengers that were very loud and unruly with their chaperones were no where to be found.

Not being able to purchase my check in baggage online was a negative.

LATE LATE LATE!!! Plagued by late AA flights on this trip. Such a drag. This one was by far the worst.

WiFi connected but only let you go to the AA website, not even text messaging worked.

Too bad that first class seats do not recline significantly causing discomfort

I think the seats on some of their planes are uncomfortable. You can be ok on a short flight of two hours but no more than that. The delays, and also the refreshments on the plane were not enough.

Flight delayed over an over all day until it cancelled at 1:30am. Would not repeatedly delay that late. Offer hotel rooms and rebook early. Very difficult for families with small children

Not sure why JAL partnered with American Airlines because their service is no where near similar. Flight attendants were not friendly and didn’t smile. Food was horrible…

this is starting to seem like an american airlines standard. delayed flights and fake apologies… getting tired of it

Terrible boarding , Business class seats are sub standard. As usual crew will miss your food too

Just get Economy Plus for international flights, so worth it the extra room, bigger seats…

Book cheap flights from Greenville to South America

Recent round-trip flight deals

5/17Fri
1 stop
10h 30mGSP-MDE
5/30Thu
1 stop
23h 40mMDE-GSP
$339
5/17Fri
1 stop
10h 30mGSP-MDE
5/30Thu
2 stops
22h 01mMDE-GSP
$368
9/23Mon
1 stopAmerican Airlines
13h 52mGSP-BOG
9/27Fri
2 stopsAmerican Airlines
13h 58mBOG-GSP
$404
9/23Mon
2 stopsDelta
16h 35mGSP-BOG
9/28Sat
1 stopDelta
17h 24mBOG-GSP
$419
9/23Mon
1 stopDelta
18h 40mGSP-BOG
9/28Sat
1 stopDelta
17h 24mBOG-GSP
$424
9/23Mon
2 stopsAmerican Airlines
18h 19mGSP-MDE
9/28Sat
2 stopsAmerican Airlines
14h 40mMDE-GSP
$455
5/30Thu
1 stopUnited Airlines
15h 35mGSP-BOG
6/9Sun
1 stopUnited Airlines
20h 41mBOG-GSP
$481
6/26Wed
2 stopsLATAM Airlines
39h 11mGSP-MDE
7/10Wed
2 stopsLATAM Airlines
28h 45mMDE-GSP
$501
5/30Thu
2 stopsUnited Airlines
16h 25mGSP-BOG
6/9Sun
1 stopUnited Airlines
20h 41mBOG-GSP
$553
7/14Sun
2 stopsLATAM Airlines
37h 00mGSP-MDE
7/17Wed
2 stopsLATAM Airlines
28h 45mMDE-GSP
$607

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Recent one-way flight deals

9/21Sat
2 stopsAmerican Airlines
19h 06mGSP-MDE
$311
9/21Sat
2 stopsAmerican Airlines
19h 06mGSP-MDE
$313
9/21Sat
3 stopsLATAM Airlines
37h 04mGSP-MDE
$374
9/21Sat
3 stopsLATAM Airlines
28h 55mGSP-MDE
$377
5/9Thu
2 stops
24h 58mGSP-MDE
$395
5/9Thu
1 stopAmerican Airlines
15h 06mGSP-MDE
$420
9/21Sat
1 stopAmerican Airlines
6h 24mGSP-MDE
$474
9/21Sat
1 stopAmerican Airlines
6h 24mGSP-MDE
$477
5/9Thu
3 stops
19h 56mGSP-MDE
$602

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Last minute flights from Greenville to South America

Last minute flight, train and bus deals

5/4Sat
multi-stopDelta
12h 56mGSP-PEI
5/11Sat
multi-stopDelta
26h 50mPEI-GSP
$923
5/4Sat
multi-stopAmerican Airlines
7h 20mGSP-PEI
5/11Sat
multi-stopAmerican Airlines
8h 38mPEI-GSP
$987
5/4Sat
multi-stopAmerican Airlines
7h 20mGSP-PEI
5/11Sat
multi-stopAmerican Airlines
20h 52mPEI-GSP
$990

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Greenville - South America Flights

Departure:

Greenville (GSP)United States

Return flight deals:

South America - Greenville

Cabin classes: