$238 Find Cheap Flights from Greenville to South America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Greenville to South America departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

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Cheap Flights from Greenville to South America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
Lima
Lima1 stop$653
Bogotá
Bogotá1 stop$518
Santiago
Santiago1 stop$734
Quito
Quito1 stop$701
Cali
Cali1 stop$562
Montevideo
Montevideo2 stops$1,156
Lima
Lima1 stop$653
Bogotá
Bogotá1 stop$518
Santiago
Santiago1 stop$734
Quito
Quito1 stop$701
Cali
Cali1 stop$562
Montevideo
Montevideo2 stops$1,156

Book Cheap Greenville to South America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Greenville to South America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Greenville to South America

Mon, Dec 8 - Fri, Mar 6
 Logo
3:00 pm - 2:16 pmGSP-MDE
23h 16m1 stop
 Logo
6:25 am - 5:53 pmMDE-GSP
11h 28m2 stops
Mon, Oct 20 - Tue, Oct 28
United Airlines Logo
7:00 am - 9:10 pmGSP-MDE
15h 10m1 stop
United Airlines Logo
9:45 am - 9:59 pmMDE-GSP
11h 14m1 stop
$506United Airlines
Find Deal
Mon, Oct 20 - Tue, Oct 28
American Airlines Logo
5:00 am - 8:15 pmGSP-MDE
16h 15m2 stops
American Airlines Logo
6:00 am - 6:40 pmMDE-GSP
11h 40m2 stops
$510American Airlines
Find Deal
Mon, Oct 20 - Tue, Oct 28
American Airlines Logo
4:46 pm - 12:35 pmGSP-MDE
20h 49m1 stop
American Airlines Logo
6:00 am - 11:21 pmMDE-GSP
16h 21m1 stop
$515American Airlines
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Thu, Jan 22 - Fri, Jan 30
Delta Logo
6:45 am - 2:15 pmGSP-CTG
7h 30m1 stop
Delta Logo
4:35 am - 8:16 pmCTG-GSP
15h 41m2 stops
$517Delta
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Thu, Sep 25 - Tue, Nov 11
Delta Logo
12:09 pm - 7:15 pmGSP-BOG
8h 06m1 stop
Delta Logo
1:35 am - 5:41 pmBOG-GSP
16h 06m2 stops
$537Delta
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Thu, Sep 25 - Sun, Nov 2
LATAM Airlines Logo
7:35 am - 7:54 pmGSP-BOG
13h 19m2 stops
LATAM Airlines Logo
3:55 pm - 11:54 pmBOG-GSP
7h 59m1 stop
$547LATAM Airlines
Find Deal
Thu, Sep 25 - Sun, Nov 2
LATAM Airlines Logo
7:35 am - 7:54 pmGSP-BOG
13h 19m2 stops
LATAM Airlines Logo
10:15 am - 11:54 pmBOG-GSP
13h 39m2 stops
$562LATAM Airlines
Find Deal
Thu, Jan 22 - Sat, Jan 31
Copa Airlines Logo
10:21 am - 11:00 pmGSP-CTG
12h 39m2 stops
Copa Airlines Logo
9:42 am - 9:49 amCTG-GSP
24h 07m2 stops
$589Copa Airlines
Find Deal
Sat, Jan 17 - Fri, Jan 23
Copa Airlines Logo
10:21 am - 10:34 pmGSP-EZE
34h 13m2 stops
Copa Airlines Logo
3:41 am - 9:49 amEZE-GSP
32h 08m2 stops
$1,388Copa Airlines
Find Deal
Booking Insights

KAYAK's insights & trends for Greenville to South America flights

Get data-powered insights and trends into flights from Greenville to South America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Greenville to South America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Greenville to South America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Greenville to South America is November, when tickets cost $604 (return) on average. On the other hand, the most expensive months are December and August, when the average cost of round-trip tickets is $929 and $826 respectively.

What’s the cheapest day of the week to fly from Greenville to South America?

The average price of all round-trip flights from Greenville to South America clicked on KAYAK for each day over the last 12 months.

When flying from Greenville to South America, you should consider leaving on a Wednesday and avoid Mondays if you are looking for the best rates. For your return to Greenville, you’ll find the best rates on Thursdays and the most expensive ones on Mondays.

Good to know

Low seasonOctober
Cheapest flight$238
Best time to beat the crowds with an average 4% drop in price.
Most popular time to fly with an average 32% increase in price.
Flight from Greenville to Bogotá

FAQs - booking South America flights

  • How does KAYAK find such low prices on flights from Greenville to South America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Greenville to South America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Greenville to South America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Greenville to South America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Greenville to South America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Greenville to South America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Greenville to South America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Greenville to South America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

  • What is the cheapest time of day to fly to South America?

    The cheapest time of day to fly to South America is generally in the evening, when round-trip flights cost $734 on average. Morning departures are around 7% more expensive than evening flights, on average. The most expensive time of day to fly to South America is generally in the morning, which is peak travel time and where the average cost of a ticket is $785.

Reviews of the top 3 airlines serving from Greenville to South America

 
Need help choosing which airline to fly with from Greenville to South America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 7982 reviews
7.9Entertainment
7.9Comfort
8.2Boarding
8.5Crew
7.3Food
Airline reviews

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

8.0 ExcellentJeanne, Aug 2025MSY - JFK
Read more Delta reviews

On this flight I felt the food offering was not as complete as on previous flights. The tomato salad was a bit off and there was nothing additional such a bread or butter. The breakfast was only one option, so you either ate what they had or ate nothing. The crew was efficient, but most seemed frustrated throughout the flight. The flight arrived early and was obstacle-free, so I’m overall quite happy, but the shine in the rest of the experience just wasn’t there.

The seats got pretty uncomfortable pretty fast. The armrests are bigger than on other planes, so I had less room in the actual seat. My butt hurt by the end of the flight. :/ comfort was the primary issue. The crew were fantastic!

I believe that a four-hour trip should have a meal. Delta had none.

Great flight with Delta! Boarding was quick and easy, the amenities were solid, and the plane was in great shape. The flight attendants had a fun, lively energy while staying professional. All in all, a smooth trip — even managed to catch up on some rest. Thanks, Delta!

I was uncomfortably cold on the plane. Other than that it was uneventful and therefore as enjoyable as a plane ride can be.

There was supposed to be a meal served, but there wasn’t and the major toilet was out of order

They made us board and then deboard due to mechanical issue which delayed the departure by almost 2 hours and we barely made our connecting flight. These quality checks should've been done before boarding not after.

Having to up charge for a seat assignment is not good. Delta can do better

I liked the friendliness of the staff. The cleanliness of all 3 planes.

Was charged for my luggage despite having been on one ticket from an international flight. Too tired to argue after 15 hours on flight. Was charged for rechecking it at JFK airport. Not sure why those off Kenya Airways were required to do that.

I’m entitled to a refund per LATAM due to the mid flight itinerary change and being stuck in São Paulo for 24 hours and needing to get a hotel. The airline was dismissive and of no help.

The flight was late. Please do not delay next time.

I couldn't travel, now I can't get a refund and to change the date I have to pay an absurd fine.

My biggest complaint is the comfort. I am not tall and there was no legroom. It was very uncomfortable. During my transfer in Sao Paola, the flight was slightly delayed so boarding was confusing because there were no instructions in English.

I never got this flight. You sent me to Chile!!! And from Chile I got the other flight to São Paulo... I've arrived 7h latter than I was supposed to arrive because of Delta delays.

Because the flight was late, we lost the connection to Brazil. You, Delta delayed, and you Delta anticipated the door closing in 15 min from Miami to GRU. Why? It caused a lot of stress! I almost could not see my mother in law alive because of your delay.

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

Wider seats, better seat cushions, (I felt like there was a board I was sitting on). I had the chicken to eat but It neither tasted nor looked like chicken. The fruit was good.

I was in the last row and they sent me to check in my luggage last minute after boarding. I had to go through the crowd.

It was good, however the airplane was really cold. We received snacks and the crew was friendly.

Pretty good. The food was just mediocre, the boarding and crew were good.

The comfort of the seats was great, the crew eased my child’s anxieties and the fact that I had full cans of my beverage choice was great.

My flight got switched and my prepaid bag didnt transfer over properly so I paid to check ANOTHER BAG. I was placed in a middle seat and it was just miserable. At least it was a bulkhead row so I had legroom. The flight just never seem3d to end

4 hours late, including over +1 hour waiting in plane to take off. Baggage left behind too.

Sat on the ground in Cincinnati for 50 minutes before deplaning

While waiting to claim my checked luggage, I discovered the airline had lost it. After a long wait and inquiries, I discovered it was on another flight. Fortunately, the airline finally sent my luggage home.

Crew should be nicer and emphatic with customers. Same cookies as the past 20 years. Seat are ok and the plane was clean though it was delayed.

Was not able to watch most shows on the entertainment site. They would not load

As smooth as you can expect. Some issues with boarding because the previous plane took forever to deplane but overall, a good experience.

On Wednesday, July 30 we were in mid flight from Manchester to Charlotte and we turned around because the right engine was malfunctioning. That was the last flight out of Manchester that night. I was rebooked for Thursday, which became a weather event Friday. There were no seats left on the flight from Manchester to Charlotte. Consequently I didn’t leave Manchester until Saturday morning and we flew to Chicago so to say the least my scheduled flight and return to Iowa was three days off and it messed with my business schedule. Consequently cash flow. I would like some sort of acknowledgment of this event.

Everything you need to know for your flight to South America

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