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Find cheap flights from Knoxville to Central America from $201

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Central America departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
sön 6/2
sön 6/9

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Best Central America Flight Deals

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours

San José
San José1 stop$325
San Salvador
San Salvador2 stops$392
Guatemala City
Guatemala City2 stops$528
Panama City
Panama City1 stop$299
Liberia
Liberia1 stop$494
Managua
Managua2 stops$414
San Pedro Sula
San Pedro Sula1 stop$360
Coxen Hole
Coxen Hole2 stops$542

Good to know

Low season

August

High season

December

Cheapest flight

$201
Best time to beat the crowds with an average 22% drop in price.
Most popular time to fly with an average 23% increase in price.
Flight from Knoxville to Guatemala City

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Knoxville to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Central America from Knoxville is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Central America with an airline and back to Knoxville with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Central America from Knoxville up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding cheap flights to Central America

  • Morning departure is around 44% cheaper than an evening flight, on average*.
*Average of the lowest prices shown in KAYAK’s search results for departures within the next 30 days

Top 3 airlines serving from Knoxville to Central America

 
Need help choosing which airline to fly with from Knoxville to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
8.0
DeltaOverall score based on 10848 reviews
8.0Entertainment
7.4Food
7.9Comfort
8.6Crew
8.2Boarding
Airline reviews

Checking in at the airport the agent only booked the first keg of my trip and had my checked luggage going to the airport with a layover! Never was issued a boarding pass for the second leg or received sticker fir my checked bag. All was well in the end! Delta agents helped to resolve the situation!!!

8.0 ExcellentAnonymous, May 2024ATL - ATW
Read more about Delta reviews

Checking in at the airport the agent only booked the first keg of my trip and had my checked luggage going to the airport with a layover! Never was issued a boarding pass for the second leg or received sticker fir my checked bag. All was well in the end! Delta agents helped to resolve the situation!!!

Delayed due to an ill passenger after loading. Not preventable on Delta's part. Was in first class. The seats are becoming worn and detaching from their velcro attachments. Only got snacks on flight. The attendant was not the friendliest.

I would fly again the whole experience was great. The only feed back I can give that they don't do that American Airlines does is the crew there is more humorous with boarding and thank their passengers. It makes it more fun to fly with them. I would however fly Delta again.

Big plane, long flight, absolutely no leg room and basically non existent air! I am 5”4’ and always travel Main Cabin, I was miserable on this plane and could barely move when we arrived in Cabo due to the cramped leg area!

From Atlanta to Cabo I would have hoped on a plane that size I would have been able to breathe and wiggle my feet a little! The leg room in that plane is non existent and I am only 5”4’. And the air vent either wasn’t working very well or just could not blow air from the ceiling to the seat area as I was suffocating through the entire flight! And please don’t say I would have been more comfortable in first class because I cannot afford those rates and have always travelled Main Cabin without issues !

The pilots were good. Disappointing when planes don't have electrical ports

I liked the piloting of the aircraft. Very disappointed about lack of electrical ports. Also, although a short flight. there was enough time to hand out snacks to comfort + seats as was done for first class.

I had a wonderful experience flying with delta. The gentleman taking care of us on our flight was so nice, accommodating, and attentive. He always was smiling and giving pins to the kids which made me smile. The flight was quick too and without turbulence. Thank you for the great flying experience.

Delta is one of the best airlines I have flown

Made the Atlanta to Pittsburgh trip many times, with Delta no issues

I paid $380 for my one-way ticket from California to Minnesota. The fair did not include online check-in. I received instructions from their app to check in at a kiosk. At the kiosk, the boarding pass would not print until an actual person came to verify that I had a personal item and not a carry-on item, On the plane, the person next to me was drunk and allowed to continue to order alcohol. United is garbage I’d rather fly spirit.

The plane was dirty and the in seat air wasn't blowing as planes usually do.

Generally good but there wasn’t any staff available when my luggage didn’t appear at baggage claim in Fresno. It took about half an hour to locate a staff member to open up the locked room where it was being kept.

Do not like the feeling of being in the basic economy. Everyone should feel good no matter what.

All flights were on time and boarding was issue free

Terrible! The plane was old and you are required to connect your own device to their Wi-Fi rather than have entertainment options in the back of the seat in front of you. The Wi-Fi went out during the flight and there was only one plug for the devices every two seats. Three out of five surrounding my family did not work. The seats and spaces under them were so small I could not fit my backpack, which I’ve always brought on flights and fit before no problem. The crew were unpleasant and patronizing.

Great! The plane was decently sized and comfortable. The staff was nice and there was great in flight entertainment

Food was terrible Not many options Stewards dont care Delay

Water service would be great. The way they board is terrible. Slow passengers first😂😂 They need to smart up a bit

Our original business class flight was cancelled so we not only downgraded but we were also spread out across the plane not sitting together in separate middle seats. My poor kids were scared and couldn’t see me on the flight and the crew wasn’t sensitive to the situation and what the airlines did to us. Very dissatisfied with United airlines.

They gave my seat away although it was a connecting flight with them and the flight was a bit delayed.

Flight was cancelled had to move to another gate late again no internet paid for the month and never can use it waste of money

Not being able to purchase my check in baggage online was a negative.

LATE LATE LATE!!! Plagued by late AA flights on this trip. Such a drag. This one was by far the worst.

WiFi connected but only let you go to the AA website, not even text messaging worked.

Too bad that first class seats do not recline significantly causing discomfort

I think the seats on some of their planes are uncomfortable. You can be ok on a short flight of two hours but no more than that. The delays, and also the refreshments on the plane were not enough.

Flight delayed over an over all day until it cancelled at 1:30am. Would not repeatedly delay that late. Offer hotel rooms and rebook early. Very difficult for families with small children

Not sure why JAL partnered with American Airlines because their service is no where near similar. Flight attendants were not friendly and didn’t smile. Food was horrible…

this is starting to seem like an american airlines standard. delayed flights and fake apologies… getting tired of it

Book cheap flights from Knoxville to Central America

Recent round-trip flight deals

9/5tors
1 stopUnited Airlines
7h 37mTYS-PTY
9/9mån
1 stopUnited Airlines
27h 24mPTY-TYS
$299
8/23fre
2 stopsAmerican Airlines
21h 56mTYS-PTY
8/26mån
2 stopsAmerican Airlines
20h 07mPTY-TYS
$306
9/5tors
2 stopsAmerican Airlines
19h 13mTYS-PTY
9/9mån
2 stopsAmerican Airlines
19h 19mPTY-TYS
$316
8/23fre
1 stopUnited Airlines
8h 19mTYS-PTY
8/26mån
1 stopUnited Airlines
20h 44mPTY-TYS
$319
7/4tors
1 stopDelta
7h 38mTYS-BZE
7/10ons
1 stopDelta
9h 19mBZE-TYS
$681
7/12fre
1 stopDelta
8h 35mTYS-PTY
7/19fre
1 stopDelta
8h 28mPTY-TYS
$683
10/11fre
2 stopsAvianca
25h 40mTYS-SJO
10/20sön
2 stopsAvianca
36h 11mSJO-TYS
$743
7/27lör
2 stopsCopa Airlines
27h 08mTYS-GUA
8/17lör
3 stopsCopa Airlines
23h 07mGUA-TYS
$790
8/23fre
3 stopsAvianca
20h 25mTYS-PTY
8/26mån
2 stopsAvianca
24h 50mPTY-TYS
$812
9/20fre
2 stopsCopa Airlines
33h 17mTYS-MGA
9/30mån
3 stopsCopa Airlines
17h 18mMGA-TYS
$840

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Recent one-way flight deals

5/30tors
3 stops
31h 43mTYS-GUA
$201
5/30tors
1 stop
19h 11mTYS-GUA
$215
5/30tors
2 stopsAmerican Airlines
9h 31mTYS-GUA
$246
6/19ons
2 stops
26h 10mTYS-LIR
$295
6/19ons
1 stopAmerican Airlines
10h 07mTYS-LIR
$462

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Last minute flights from Knoxville to Central America

Last minute flight, train and bus deals

5/6mån
multi-stopAmerican Airlines
15h 10mTYS-MGA
5/8ons
multi-stopAmerican Airlines
24h 16mMGA-TYS
$529
5/6mån
multi-stopAmerican Airlines
15h 10mTYS-MGA
5/8ons
multi-stopAmerican Airlines
21h 08mMGA-TYS
$530
5/6mån
multi-stopAmerican Airlines
6h 58mTYS-MGA
5/8ons
multi-stopAmerican Airlines
24h 16mMGA-TYS
$531
5/6mån
multi-stopAmerican Airlines
14h 10mTYS-MGA
5/8ons
multi-stopAmerican Airlines
17h 41mMGA-TYS
$532
5/6mån
multi-stopAmerican Airlines
6h 58mTYS-MGA
5/8ons
multi-stopAmerican Airlines
8h 42mMGA-TYS
$623
5/6mån
multi-stopAmerican Airlines
14h 10mTYS-MGA
5/8ons
multi-stopAmerican Airlines
15h 17mMGA-TYS
$633
5/6mån
multi-stopAmerican Airlines
6h 19mTYS-SJO
5/13mån
multi-stopAmerican Airlines
16h 27mSJO-TYS
$662
5/6mån
multi-stopUnited Airlines
13h 49mTYS-GUA
5/10fre
multi-stopUnited Airlines
11h 49mGUA-TYS
$955
5/6mån
multi-stopAeromexico
19h 25mTYS-GUA
5/10fre
multi-stopAeromexico
24h 06mGUA-TYS
$1,395
5/6mån
multi-stopCopa Airlines
27h 00mTYS-GUA
5/10fre
multi-stopCopa Airlines
23h 08mGUA-TYS
$1,762

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Knoxville - Central America Flights

Departure:

Knoxville (TYS)United States

Return flight deals:

Central America - Knoxville

Cabin classes: