$171 Find Cheap Flights from Knoxville to Central America

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Knoxville to Central America departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap Flights from Knoxville to Central America

Cheapest round-trip prices found by our users on KAYAK in the last 72 hours
San Salvador
San Salvador1 stop$483
San José
San José1 stop$431
Guatemala City
Guatemala City1 stop$430
Panama City
Panama City2 stops$531
Liberia
Liberia1 stop$628
Managua
Managua1 stop$543
San Pedro Sula
San Pedro Sula2 stops$444
Coxen Hole
Coxen Hole2 stops$582
San Salvador
San Salvador1 stop$483
San José
San José1 stop$431
Guatemala City
Guatemala City1 stop$430
Panama City
Panama City2 stops$531
Liberia
Liberia1 stop$628
Managua
Managua1 stop$543
San Pedro Sula
San Pedro Sula2 stops$444
Coxen Hole
Coxen Hole2 stops$582

Book Cheap Knoxville to Central America Plane Tickets

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Knoxville to Central America that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Knoxville to Central America

Sun, Apr 12 - Sun, Apr 19
Multiple Airlines Logo
8:20 am - 11:32 am
TYS
-
GUA
29h 12m
1 stop
Multiple Airlines Logo
12:10 pm - 12:25 pm
GUA
-
TYS
22h 15m
1 stop
$430Multiple Airlines
Sat, May 30 - Sun, Jun 7
Multiple Airlines Logo
5:11 pm - 11:33 am
TYS
-
SJO
20h 22m
1 stop
Multiple Airlines Logo
12:38 pm - 11:39 pm
SJO
-
TYS
33h 01m
2 stops
$431Multiple Airlines
Sun, May 3 - Sun, May 10
Multiple Airlines Logo
9:25 pm - 11:33 am
TYS
-
SJO
16h 08m
1 stop
Multiple Airlines Logo
12:38 pm - 12:25 pm
SJO
-
TYS
21h 47m
1 stop
$433Multiple Airlines
Sun, May 3 - Sun, May 10
Multiple Airlines Logo
11:27 am - 11:40 pm
TYS
-
SJO
14h 13m
2 stops
Multiple Airlines Logo
12:38 pm - 12:25 pm
SJO
-
TYS
21h 47m
1 stop
$439Multiple Airlines
Sun, Apr 12 - Sun, Apr 19
Multiple Airlines Logo
9:33 pm - 11:32 am
TYS
-
GUA
15h 59m
1 stop
Multiple Airlines Logo
12:10 pm - 9:48 pm
GUA
-
TYS
31h 38m
2 stops
$454Multiple Airlines
Tue, May 19 - Fri, May 29
Southwest Logo
7:05 am - 7:00 pm
TYS
-
SJO
13h 55m
2 stops
Southwest Logo
9:00 am - 6:10 pm
SJO
-
TYS
7h 10m
1 stop
$502Southwest
Wed, Jun 10 - Mon, Aug 3
United Airlines Logo
5:45 am - 11:29 am
TYS
-
SAL
7h 44m
1 stop
United Airlines Logo
1:15 am - 6:07 pm
SAL
-
TYS
14h 52m
1 stop
$509United Airlines
Wed, Jun 3 - Mon, Aug 17
United Airlines Logo
7:19 pm - 11:29 am
TYS
-
SAL
18h 10m
1 stop
United Airlines Logo
3:40 pm - 10:08 am
SAL
-
TYS
16h 28m
2 stops
$513United Airlines
Wed, May 27 - Wed, Aug 12
American Airlines Logo
6:00 am - 6:42 pm
TYS
-
SAL
14h 42m
1 stop
American Airlines Logo
12:40 pm - 6:40 pm
SAL
-
TYS
28h 00m
1 stop
$520American Airlines
Mon, May 25 - Wed, Jun 3
American Airlines Logo
6:07 pm - 12:13 pm
TYS
-
PTY
19h 06m
2 stops
American Airlines Logo
1:14 pm - 10:48 am
PTY
-
TYS
20h 34m
2 stops
$531American Airlines
Booking Insights

KAYAK's insights & trends for Knoxville to Central America flights

Get data-powered insights and trends into flights from Knoxville to Central America to help you find the cheapest flights, the best time to fly and much more.

What is the cheapest month to fly from Knoxville to Central America?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Knoxville to Central America, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Knoxville to Central America is May, when tickets cost $292 (return) on average. On the other hand, the most expensive months are April and December, when the average cost of round-trip tickets is $739 and $682 respectively.

Good to know

Low seasonSeptember
Cheapest flight$171
Best time to beat the crowds with an average 16% drop in price.
Most popular time to fly and prices are also 19% lower on average.
Flight from Knoxville to San Salvador

FAQs - booking Central America flights

  • How does KAYAK find such low prices on flights from Knoxville to Central America?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Knoxville to Central America.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Knoxville to Central America?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight from Knoxville to Central America is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Knoxville to Central America?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly from Knoxville to Central America with an airline and back with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Knoxville to Central America?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying from Knoxville to Central America up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 3 airlines serving from Knoxville to Central America

 
Need help choosing which airline to fly with from Knoxville to Central America? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.9
DeltaOverall score based on 8302 reviews
7.9Comfort
8.1Boarding
7.2Food
7.8Entertainment
8.5Crew
Airline reviews

This was a Latam operated flight. Seats seemed a bit narrow in business class. Older aircraft.

8.0 ExcellentSunderesh, Mar 2026
ATL - LIM
Read more Delta reviews

This was a Latam operated flight. Seats seemed a bit narrow in business class. Older aircraft.

I had a flight cancel and had it rerouted. When the rerouted they put me at a window seat instead of an isle. It was hard sitting by the window because the couple with masks on were making out. I get motion sickness which is why I need to have the isle seat.

NEVER MADE THE FLIGHT BECAUSE DELTA SAID THEY CAN NOT

THEY FAILED ME AND I NEVER GOT ON THE FLIGHT BECAUSE IT WAS SO DELAYED! I ENDED UP HAVING TO PAY OUT OF POCKET FOR A HOTEL AND STAY IN NASHVILLE TO CATCH A FLIGHT FOR THE FOLLOWING DAY. DELTA IS POOR CUSTOMER SERVICE>

8 hours late and the plane smelled like urine, that smell in the morning when your child wet the bed in the night.

My flight was canceled on Sunday. Rebooking took three hours. Had to pay for accommodations another night. New flight was delayed for 5 hours, all that was sent was a 12 dollar food voucher, which doesn’t tell you how to use it. Then when we landed we had to sit on the plane for an hour before we could get off.

Miserable. This entire round trip was miserable. I booked evening flights to and from Detroit on consecutive days that should have had me at my destination by 10:30. Instead I arrived after 3am on my flight to Detroit and after midnight on my return. Multiple unforced errors like awaiting bags to get put on the plane for almost an hour in Detroit and a 20 minute delay to pull up to the gate in Atlanta has me rethinking my assumption that delta is the best and most reliable airline

Perhaps when you’re sitting in 1st class and the crew closes the bathroom for the pilots, there could be a notification other than holding your hands up as a blockade when you get there and you’re told the restrooms are closed please turn around … especially at night when visibility is poor and you’re met by a flight attendants with their arms up

First class is comfortable. Enjoyed a movie and was able to relax compared to coach.

Loved flying First Class. Very comfortable. The seat was amazing. Enjoyed a movie and was able to relax so much better than in coach.

Experience was great - no complaints. Took off on time, landed early. Got to the gate relatively quickly - took a little bit of extra time to deplane but nothing excessive.

Business class seats felt very cramped compared to other airlines.

Economy plus was so cramped I could not use my laptop. It was beyond bad.

OK, we were delayed and had to de plane and reboard.

United is one airline which regardless of how many separate United tickets in existence, if one flight breaks down, the airline will take care of all the flights.

Both our flights were delayed. Almost didn’t get in the second flight. Staff was rude to the bone.

Both my flight where delayed Had 25min to make it to my transfer flight

Everything was on time and service on the flight was great!

Wifi Bluetooth features for watching in flight movie was horrible. Screen kept blacking out no connection of sound although it said connected. Other than that smooth trip .

The 777’s economy seat’s legroom was more tolerable than expected. I appreciate the reclining mechanism which slides the seat forward to minimize cannibalizing the space behind. The food was terrible: very salty.

They put me on an earlier and I got home sooner

Not good. One of my luggage is missing. And until now they can’t find it

Horrible experience upon landing. Probably more due to DCA utter incompetence than AA.

Jill was the flight attendant in first class she was fabulous!! Best flight attendant I have had in years.!! And I fly every other week. Other can learn from her!!

Really good. I accidentally left my duffel on the plane and the reps were so friendly in retrieving it.

My 9:50AM flight was delayed to 3:40PM "due to incoming aircraft delay". No aircraft is "delayed" that long. Found out once we did board (after several changes in times) that the aircraft had a maintenance issue and we had to wait for another aircraft. Just tell us that. The aircraft we did get was old and the seats need to be updated. I have been traveling for several weeks with AA and you should refresh your entertainment content as frequent flyers have gone through most of your new content. I have Celiac and a shellfish allergy and continue to have struggles with meals on business and first class flights. Please keep this in mind. Sorry - was a long travel day yesterday and a bit cranky this morning with my experience comments. Still an AA fan.

The business steward was absolutely amazing! Smiles and kindness! Wish all AA flights are like this one!

As a first class customer, there was no power the entire flight which limited my ability to work. I find this unacceptable. The first 11 rows on the left side of the plan were out. I was only offered the option to charge my phone which was not the issue because my laptop was out of power. I asked if there was anything that can be done for me, and the answer was, "no". I was not offered any type of compensation for this AA problem which caused me unnecessary stress due to inability to address business issues on an already challenging travel day. Flight attendants tried to reset the power once but that was the extent of their support. Very disappointing for the lack of expected services on a flight. Please contact me with customer focused response to this complaint.

Not really sure I enjoyed the flight at all. The flight attendants seemed a little tired and rude at times. The snacks were lacking in taste and sustenance. The flight was incredibly turbulent for three plus hours and the pilot had to do a second pass to land at our final destination because he was coming in so fast. He must have taken a short cut and because of it we had to suffer the violent turbulence and the dropping down. It had to be one of if not the worse flights I have ever been on and have traveled vastly all over the world.

Delay after delay with little communication then AA lost my luggage and at airport would not assist just said scan this QR code to track your luggage and submit a claim. However QR code provided did not work so have to go back to airport

Everything you need to know for your flight to Central America

Information on your arrival and departure airports