MDE - SCL

$197 Find Cheap Flights from Medellín to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Medellín to Santiago departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
1 adult, Economy

KAYAK searches hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Medellín to Santiago, as well as popular online travel agencies
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Flights Deals

Cheap Flights from Medellín to Santiago (MDE-SCL)

 
Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Medellín to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Medellín to Santiago

Sun, Dec 7 - Sun, Feb 22
JetSMART Logo
2:13 pm - 10:21 pmMDE-SCL
6h 08mnonstop
JetSMART Logo
4:33 pm - 11:37 pmSCL-MDE
9h 04m1 stop
$323JetSMART
Find Deal
Mon, Dec 8 - Sat, Feb 21
JetSMART Logo
2:13 pm - 10:21 pmMDE-SCL
6h 08mnonstop
JetSMART Logo
4:33 pm - 11:17 pmSCL-MDE
8h 44m1 stop
$326JetSMART
Find Deal
Sun, Dec 7 - Sat, Feb 21
JetSMART Logo
2:13 pm - 10:21 pmMDE-SCL
6h 08mnonstop
JetSMART Logo
4:33 pm - 11:17 pmSCL-MDE
8h 44m1 stop
$327JetSMART
Find Deal
Mon, Dec 8 - Sun, Feb 22
JetSMART Logo
2:13 pm - 10:21 pmMDE-SCL
6h 08mnonstop
JetSMART Logo
4:33 pm - 11:37 pmSCL-MDE
9h 04m1 stop
$328JetSMART
Find Deal
Wed, Dec 10 - Fri, Feb 20
JetSMART Logo
2:13 pm - 10:21 pmMDE-SCL
6h 08mnonstop
JetSMART Logo
7:49 am - 12:13 pmSCL-MDE
6h 24mnonstop
$329JetSMART
Find Deal
Wed, Dec 10 - Wed, Feb 18
JetSMART Logo
2:13 pm - 10:21 pmMDE-SCL
6h 08mnonstop
JetSMART Logo
4:33 pm - 11:03 pmSCL-MDE
8h 30m1 stop
$330JetSMART
Find Deal
Wed, Dec 10 - Mon, Feb 16
JetSMART Logo
2:13 pm - 10:21 pmMDE-SCL
6h 08mnonstop
JetSMART Logo
4:33 pm - 11:02 pmSCL-MDE
8h 29m1 stop
$333JetSMART
Find Deal
Sun, Dec 7 - Fri, Feb 20
JetSMART Logo
2:13 pm - 10:21 pmMDE-SCL
6h 08mnonstop
JetSMART Logo
7:49 am - 12:13 pmSCL-MDE
6h 24mnonstop
$334JetSMART
Find Deal
Sun, Dec 7 - Sun, Feb 22
 Logo
2:13 pm - 10:21 pmMDE-SCL
6h 08mnonstop
 Logo
3:25 pm - 9:55 pmSCL-MDE
8h 30m1 stop
Wed, Dec 10 - Sat, Feb 21
 Logo
2:13 pm - 10:21 pmMDE-SCL
6h 08mnonstop
 Logo
6:55 am - 1:19 pmSCL-MDE
8h 24m1 stop
Expert advice

Expert advice for your flight from Medellín to Santiago

 
Snippets provided in this section are AI-generated based on a summarization of KAYAK-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
KAYAK teamed up with top travel experts to share the best tips for your journey.
Airlines
JetSMART

JetSMART's FlySMART fare includes only a small handbag; additional baggage incurs extra fees.


JetSMART offers priority boarding for a nominal fee, useful during busy travel periods.

Read more about JetSMARTby Daniel Scheffler
Avianca

Avianca's Classic fare includes a carry-on, checked bag, and seat selection, ideal for longer flights.


Avianca's Business class offers lounge access and extra baggage, enhancing comfort on long-haul flights.

Our travel experts
Daniel Scheffler

Daniel Scheffler

Expert on JetSMART

Daniel Scheffler

Daniel Scheffler

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Read more
Mark Chesnut

Mark Chesnut

Expert on Avianca

Mark Chesnut

Mark Chesnut

Mark Chesnut is a travel writer and public speaker with more than 30 years of experience. The 2019 winner of the NLGJA Excellence in Travel Writing Award, Mark is the author of the book “Prepare for Departure” and has covered air travel for multiple top consumer and trade media outlets.

Read more
Useful Info

KAYAK's insights & trends for Medellín to Santiago flights

Get data-powered insights and trends into flights from Medellín to Santiago to help you find the cheapest flights, the best time to fly and much more.

How much is a round-trip flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

What’s the cheapest day of the week to fly from Medellín to Santiago?

The average price of all round-trip flights from Medellín Jose Maria Cordova Intl Airport to Santiago clicked on KAYAK for each day over the last 12 months.

When flying from Medellín to Santiago, you should consider leaving on a Tuesday and avoid Sundays if you are looking for the best rates. For your return to Medellín, you’ll find the best rates on Sundays and the most expensive ones on Wednesdays.

What is the cheapest month to fly from Medellín Jose Maria Cordova Intl Airport to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.

The cheapest month for flights from Medellín Jose Maria Cordova Intl Airport to Santiago is October, where tickets cost $322 (return) on average. On the other hand, the most expensive months are February and January, where the average cost of round-trip tickets is $397 and $388 respectively.

How far in advance should I book a flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

To calculate weekly average prices, KAYAK takes all prices for each week before departure over the last year for round-trip flights from Medellín Jose Maria Cordova Intl Airport to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each week.

To get a below average price on the flight from Medellín Jose Maria Cordova Intl Airport to Santiago, you should book around 4 weeks before departure. For the absolute cheapest price, our data suggests you should book 19 weeks before departure.

Good to know

Low seasonMay
High seasonDecember
Cheapest flight$197
Best time to beat the crowds but there is an average 4% increase in price.
Most popular time to fly with an average 1% increase in price.
Flight from Medellín to Santiago

When to book flights from Medellín to Santiago

Are your dates flexible? Find out the best times to travel from Medellín to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking Medellín to Santiago flights

  • What is the cheapest flight from Medellín Jose Maria Cordova Intl Airport to Santiago?

    In the last 3 days, the lowest price for a flight from Medellín Jose Maria Cordova Intl Airport to Santiago was $197 for a one-way ticket and $323 for a round-trip.

  • Do I need a passport to fly between Medellín and Santiago?

    A passport is required to fly from Medellín to Santiago.

  • Which aircraft models fly most regularly from Medellín to Santiago?

    The Airbus A320-100/200 is the aircraft model that flies most regularly on the Medellín to Santiago flight route.

  • Which airline alliances offer flights from Medellín to Santiago?

    Star Alliance is the only airline alliance operating flights between Medellín and Santiago.

  • Which is the best airline for flights from Medellín to Santiago, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Medellín to Santiago are Copa Airlines and LATAM Airlines. With an average price for the route of $336 and an overall rating of 7.5, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $390 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Medellín to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Medellín to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Medellín to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Medellín is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Medellín to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Medellín with another airline. Booking your flights between Medellín and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Medellín to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Medellín up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

Reviews of the top 4 airlines serving from Medellín to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Medellín to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Medellín to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.5
LATAM AirlinesOverall score based on 1805 reviews
7.4Comfort
7.6Boarding
8.1Crew
7.0Entertainment
6.7Food
Airline reviews

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

6.0 GoodDiane, Jul 2025ATL - PDX
Read more LATAM Airlines reviews

Boarding was done by woman who insisted on strict standing in line policy; food was ok; entertainment minimal

It was a very good flight, no entertainment is the reason for not checking that box.

Our flight was cancelled and it took them 5 hours to reschedule and the next morning they said we still didn’t have a new ticket.

I travel often with LATAM, it never disappoints me. The service is great, nice crew, latest and some classic movies. I got 3 small meals, cannot complaint. I’ll definitely travel again with them.

We departed and landed on time, the aircraft was clean and comfortable, the crew were lovely. Online checkin worked well and the self service bag drop at the airport worked well. The a/c was an Airbus A330 and has been fitted with a good entertainment system with lots of choice in many languages. The price I paid for the flight was competitive with other airlines apart from the budget carriers, none of whom I was familiar with so I stuck to an airline I have used in previous visits to South America.

We didn’t have any entertainment. I tried to go online without success. The airplane was extremely cold and they didn’t have blankets.

Not sure why there are so many security checks at this airport. Consistently annoying showing passport over and over, checking carryons at gate all the while trying to make tight connection. Basically it was uncomfortable crowded cabin with meidiocre service

Change of gate in Santiago devolved into half plus hour delay and a really tight connection in Lima

Although the flight is goof and the crew is good, the way the airline charges you for every service is ridiculous.

They didi not provide wheelchair though we had requested. We had to run around for 40 minutes and arrange it from the airport!

Had to go through security at the gate again. Had to take off shoes and go through the whole thing again even though we have global entry. They asked us to check in items bought at duty free during our layover and since we checked our luggage at the original departure airport, they forced us to check in a small backpack. None of this ever happened with other airlines. In addition, no vegetarian food option and no snacks during a 7 hr flight. Luggage limits are unusually small. This is unacceptable. Will NEVER fly Copa again and will tell friends and family to avoid this airline.

We had a five hour layover in the way home from Colombia. I read the "bout your flight" email carefully before we checked bags. We had to go through security right at the gate. Almost lost our ground coffee because that airport only allows 16 ounce of coffee and we had 18. I've been to 48 countries and never heard of a coffee restriction. I can't follow a rule I don't know about. I requested they bring our coffee to our checked luggage. Instead tey gate checked our bag for free. Back to planning transfers in Dallas I guess

It was ok. However, the food was quite poor since I don't eat pasta.

Tell people to remain in their seats during the meal/beverage distribution. Enforce boarding by group numbers. No one was checking. Tell people to turn their electronics speakers off. Bigger cups for drinks.

Enforce the boarding process by group numbers. Tell people to stay seated during the meal/drink distribution. It took forever to get food and drinks because people would not stay out the isle and let the crew do their jobs. Everyone wanted to go to the bathroom forcing the crew to enter and leave the isle constantly so people can pass. Tell people to keep their electronics off speaker mode. No one wants to hear phone conversations and music playing.

There was no individual at the front check in when I arrived. I waited for at least 15 minutes and walked around asking security/janitors if they could help and they did not have a solution. So I had to take my checked bag through security and they threw away some of my items. I ended up making it to the gate only a few minutes before it closed due to my waiting for an agent at check in.

We were in transit from Lima (flight at 1.10am) and we were in stand by in our flight from Panama to Washington. We wait from 4.30 am to 18.30pm in the Airport. The company give us 2 x 15 dollars for eat during the day and a personnal travel voucher of 400 dollars each. Do they buy food one time something in the Airport ??? And one of us live in France so the voucher is not usable. More than 24 hours travel !! And our place were near the toilets, with 8 children around us. The boy behind my seat stamped his feet on my back all the flight. Really Wonder full ! So we are totally unhappy with our travel. Thanks Copa Airlines....

My flight delayed and i misss the connection they send me to orlando no to tampa i have to pay a uber to my house

It would have been better if they don't separate families in seating. We were seated in the aile row in the middle of a family of four. It would have been better if they they seat the family of four together than separated.

It was reasonably comfortable trip considering its duration (7 hours). Crew was very good and friendly, seats very more comfortable than other planes. Only negative comment would be that the bathroom light did not get its full brightness 🙃

Late departure. When the flight arrived in Medellin the plane sat at the gate for 20 minutes waiting for a bus for us to get off the plane.

i think the flight was late because they were so strict about measuring everyone's personal items to try and charge them $119. It was really petty and made us late.

Terrible, We had to stay in Bogota for two days due to weather but the airline did not provide for the same day flight. Only two days later

Business class seats did not lie flat. There was only powdered milk for your coffee....in Business Class!! Food was good.

Boarding was somewhat confusing in that the wrong messages were being displayed at the gate. It was somewhat annoying that I got off one flight and straight onto another (from the same gate), but in between they re-checked my hand luggage and made me get rid of my water (which they charge for on the plane). I was sitting in their 'Plus' seating, but the leg room was still too small to be able to sit square. The food options on the flights are pretty cheap quality (but not price). They got me from 'A' to 'B' on-time and for a relatively good price, but the experience itself was below average.

So so, you feel like you have to pay for everything each time

COP 7,000 for a cup of mediocre coffee. I thought I was on Spirit Airlines for a minute. Otherwise the flight was fine. Nothing exceptional to report.

Overpriced checked bag price of $120 and they charge you for carryon if the size is not minimal of $120.

Be very careful of the initial low price because Avianca wil bill you for a carryon of $120 or a checked bag for $120. Also, be careful with connections because the customs entry process is slow and the connecting terminal is not close.

My whole return flight itinerary, 3 flights, got canceled without any warning to me because I missed one of the earlier flights 3 weeks ago

The crew was polite, the Captain specially was cool! But the onboard service was nonexistent: No entertainment, no food, no reclining seats. I know it is a low cost, but the cost of the ticket was not so low for just the transport service.

Was a good flight, no delays and good customer service.

Customer service is horrible. Our flight was at 9pm and we were at check in counter by 7pm. The crew strolls in at 7.30 without even an apology. We were suppose to get our boarding passes online but the website was not working at expected and the staff kept arguing with us saying that is not possible.

There was no entertainment but everyone just used their phones.

The app told us that carry on luggage was included but we were made to pay for it again at the check in counter, making it a very expensive flight. Not happy

I was charged 168 soles for kids stroller. We have travelled across the world and have never charged for the stroller. Horrific airlines and the staff was extremely rude. They wouldn’t let us board unless we pay the extra baggage cost. Never ever flying this airline and I would recommend the same for the others.

Avoid this airline. They are unprofessional. The captain left several passengers on ground due to covid restrictions which were never communicated. As a chilean, I am ashamed that this low level airline comes from my country. Remember this horrible brand and avoid it... Jetsmart

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