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MEX - SCL

$274 Find cheap flights from Mexico City to Santiago

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight from Mexico City to Santiago departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Mon 6/3
Mon 6/10

Search hundreds of travel sites at once for deals on flights to Santiago

 
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Santiago, as well as popular online travel agencies
These are the airlines KAYAK users have selected most often from within our search results in flight searches from Mexico City to Santiago, as well as popular online travel agencies
In the last 7 days travelers have searched 43,369,418 times on KAYAK, and here is why:

Save 22% or moreCompare multiple travel sites with one search.

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Filter your dealsChoose cabin class, free Wi-Fi and more.

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Cheap flight deals from Mexico City to Santiago (MEX-SCL)

Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from Mexico City to Santiago that are departing in the next months. While these flights were available on KAYAK in the last 72 hours, prices and availability are subject to change and deals may expire.
Discover the best prices and deals for you by selecting your travel dates.
Choose your dates
10:25 pm - 8:55 pmMEX-SCL
20h 30m1 stop
9:45 pm - 11:30 amSCL-MEX
15h 45m1 stop
Thu, May 23 - Tue, Jun 4
2:00 pm - 1:25 pmMEX-SCL
21h 25m1 stop
2:30 pm - 12:05 pmSCL-MEX
23h 35m1 stop
$538Avianca
Find Deal
Thu, Aug 29 - Thu, Sep 5
3:25 pm - 4:35 pmMEX-SCL
23h 10m1 stop
12:30 am - 11:20 amSCL-MEX
12h 50m1 stop
Mon, Jul 8 - Sun, Jul 21
3:25 pm - 12:25 pmMEX-SCL
19h 00m2 stops
12:30 am - 11:20 amSCL-MEX
12h 50m1 stop
Mon, Jul 8 - Sun, Jul 21
3:25 pm - 12:20 amMEX-SCL
29h 55m1 stop
12:10 am - 5:55 amSCL-MEX
8h 45mnonstop
$552LATAM Airlines
Find Deal
Mon, Sep 23 - Sun, Sep 29
3:25 pm - 9:15 pmMEX-SCL
27h 50m1 stop
12:30 am - 8:15 pmSCL-MEX
21h 45m1 stop
Tue, Aug 27 - Mon, Sep 2
3:25 pm - 5:25 amMEX-SCL
12h 00m1 stop
11:10 pm - 5:55 amSCL-MEX
8h 45mnonstop
$558LATAM Airlines
Find Deal
Thu, Jun 6 - Thu, Jun 13
3:25 pm - 11:32 amMEX-SCL
17h 07m2 stops
12:10 am - 5:55 amSCL-MEX
8h 45mnonstop
$559LATAM Airlines
Find Deal
Mon, Sep 23 - Sun, Sep 29
9:50 am - 11:18 pmMEX-SCL
11h 28m1 stop
4:13 am - 12:15 amSCL-MEX
22h 02m1 stop
$575Copa Airlines
Find Deal
Tue, May 14 - Tue, May 21
9:50 am - 2:30 amMEX-SCL
14h 40m1 stop
4:12 am - 12:15 amSCL-MEX
22h 03m1 stop
$613Copa Airlines
Find Deal
Mon, Aug 26 - Wed, Aug 28

Flights from Mexico City to Santiago - Travel Insights & Trends

Get data-powered insights and trends into flights from Mexico City to Santiago to help you find the cheapest flights, the best time to fly and much more.

What’s the cheapest day of the week to fly from Mexico City to Santiago?

The average price of all flights from Mexico City to Santiago clicked on KAYAK for each day over the last 12 months.
Your flight ticket price will generally be cheaper if you fly to Santiago on a Thursday and more expensive on a Saturday. On your return trip to Mexico City, you should consider flying back on a Monday, and avoid Thursdays for better deals.

What is the cheapest month to fly from Mexico City to Santiago?

To calculate monthly average prices, KAYAK takes all prices for each month over the last year for flights from Mexico City to Santiago, removes the top 0.1% to account for outliers, and then takes the median of all values for each month.
The cheapest month for flights from Mexico City to Santiago is April, where tickets cost $556 on average. On the other hand, the most expensive months are December and January, where the average cost of tickets is $830 and $722 respectively.

How far in advance should I book a flight from Mexico City to Santiago?

To calculate daily average prices, KAYAK takes all prices for each day before departure over the last year for flights from Mexico City to Santiago, removes the top 0.1% to account for outliers, and then takes the average of all the values for each month.
To get a below average price on the flight from Mexico City to Santiago, you should book around 4 days before departure. For the absolute cheapest price, our data suggests you should book 58 days before departure.

Which airlines provide the cheapest flights from Mexico City to Santiago?

The cheapest price for the route for each airline clicked by KAYAK users in the last 72 hours.
In the last 3 days, Avianca offered the best one-way deal for that route, at $274. KAYAK users also found Mexico City to Santiago round-trip flights on Avianca from $538 and on LATAM Airlines from $552.

Which airlines fly non-stop between Mexico City and Santiago?

Airline and price data is aggregated from results in KAYAK’s search results from the last 2 weeks for flights from Mexico City to Santiago.
There is just one airline that flies from Mexico City to Santiago direct and that is LATAM Airlines. The best one-way deal found from LATAM Airlines for the route is $523.

How many flights are there between Mexico City and Santiago per day?

There is a maximum of 1 nonstop flight a day that takes off from Mexico City and lands in Santiago, with an average flight time of 8h 15m. The most common departure time is 7:00 am and most flights take off in the morning. Each week, there are 7 flights.

Which cabin class options are there for flights between Mexico City and Santiago?

The average price of flights for each cabin class for the route found by users searching on KAYAK over the last 2 weeks.
There are 2 cabin class options for the route. These are Business and Economy. Perform a search on KAYAK to find the latest prices and availability for all cabin fares, which differ across airlines.

How long does a flight from Mexico City to Santiago take?

Nonstop flights from Mexico City generally make it to Santiago in 8h 15m. The flying distance between the two cities is 4,096 miles.

What’s the earliest departure time from Mexico City to Santiago?

Early birds can take the earliest flight from Mexico City at 7:30 am and will be landing in Santiago at 5:45 pm.

What’s the latest departure time from Mexico City to Santiago?

If you prefer to fly at night, the latest flight from Mexico City to Santiago jets off at 7:30 am and lands at 5:45 pm.

Good to know

Low season

June

High season

December

Cheapest flight

$274
Best time to beat the crowds with an average 7% drop in price.
Most popular time to fly with an average 28% increase in price.
Flight from Mexico City to Santiago

When to book flights from Mexico City to Santiago

Are your dates flexible? Find out the best times to travel from Mexico City to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price
KAYAK looks at all historical flight data for each date to provide a predicted price for one-way trips or round-trips with a duration up to 40 days. While we try to provide actual minimum prices for each date, some prices are predictions and actual prices may differ.

FAQs for booking flights from Mexico City to Santiago

  • What is the cheapest flight from Mexico City to Santiago?

    In the last 3 days, the lowest price for a flight from Mexico City to Santiago was $274 for a one-way ticket and $472 for a round-trip.

  • Do I need a passport to fly between Mexico City and Santiago?

    Yes

  • Which airports will I be using when flying from Mexico City to Santiago?

    Mexico City airport is called Mexico City Benito Juarez and the only airport in Santiago is Santiago Arturo Merino Benitez.

  • Which airlines offer Wi-Fi service onboard planes from Mexico City to Santiago?

    Delta, and Aeromexico offer inflight Wi-Fi service on the Mexico City to Santiago flight route.

  • Which aircraft models fly most regularly from Mexico City to Santiago?

    The Boeing 787-8 Dreamliner is the aircraft model that flies most regularly on the Mexico City to Santiago flight route.

  • On which days can I fly direct from Mexico City to Santiago?

    There are nonstop flights from Mexico City to Santiago on a daily basis.

  • Which is the best airline for flights from Mexico City to Santiago, Copa Airlines or LATAM Airlines?

    The two airlines most popular with KAYAK users for flights from Mexico City to Santiago are Copa Airlines and LATAM Airlines. With an average price for the route of $595 and an overall rating of 7.8, Copa Airlines is the most popular choice. LATAM Airlines is also a great choice for the route, with an average price of $754 and an overall rating of 7.5.

  • How does KAYAK find such low prices on flights from Mexico City to Santiago?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Mexico City to Santiago.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Mexico City to Santiago?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Santiago from Mexico City is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Mexico City to Santiago?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Santiago with an airline and back to Mexico City with another airline. Booking your flights between Mexico City and SCL can sometimes prove cheaper using this method.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Mexico City to Santiago?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Santiago from Mexico City up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Top tips for finding a cheap flight from MEX to Santiago

  • Looking for a cheap flight? 25% of our users found flights on this route for $294 or less one-way and $537 or less round-trip.

Prefer to fly non-stop from Mexico City to Santiago?

Find which airlines fly direct from Benito Juarez to Arturo Merino Benitez, which days they fly and book direct flights.

Nonstop departures

Mexico City Benito Juarez to Santiago Arturo Merino Benitez

Monday

LATAM Airlines

LATAM Airlines

Tuesday

LATAM Airlines

LATAM Airlines

Wednesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Friday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights

Nonstop returns

Santiago Arturo Merino Benitez to Mexico City Benito Juarez

Monday

LATAM Airlines

LATAM Airlines

Tuesday

LATAM Airlines

LATAM Airlines

Wednesday

LATAM Airlines

LATAM Airlines

Thursday

LATAM Airlines

LATAM Airlines

Friday

LATAM Airlines

LATAM Airlines

Saturday

LATAM Airlines

LATAM Airlines

Sunday

LATAM Airlines

LATAM Airlines

See more direct flights
See more direct flights

Top 4 airlines serving from Mexico City to Santiago

 
See real verified KAYAK customer reviews for airlines flying from Mexico City to Santiago. Airline scores are aggregated from all reviews left by passengers on KAYAK after flying with an airline. KAYAK doesn’t show reviews that are older than 5 years. Learn how KAYAK collects reviews.
Need help choosing which airline to fly with from Mexico City to Santiago? KAYAK airline reviews give an overall score for each airline based on loads of factors, including comfort, boarding, in-flight entertainment and more, to make your decision easier. See airline scores according to verified KAYAK customer reviews.
7.8
Copa AirlinesOverall score based on 2799 reviews
8.1Boarding
7.2Entertainment
7.7Comfort
8.3Crew
7.3Food
Airline reviews
Pros: "Boarding was organized"
Cons: "They didn’t turn on AC until we landed in Lima, during bording they were hurrying people to get on their seats fast"
4.0 OkayAnonymous, May 2021PTY - LIM
Read more about Copa Airlines reviews
Pros: "Boarding was organized"
Cons: "They didn’t turn on AC until we landed in Lima, during bording they were hurrying people to get on their seats fast"
Pros: "You are so good all the time."
Cons: "We understand that this time is tough because the Coronavirus, they took care of all of us, and also they were kind and friendly. Thank you so much, for everything"
Pros: "Crew was great. Supportive and friendly. Plane was clean and comfortable."
Cons: "This flight didn’t appear in AeroMexico’s system. We had to get our boarding passes in Mexico city, but our original departure was from YUL."
Pros: "nice crew."
Cons: "seats were too small and uncomfortable, not possible to lean back much because of a tall passenger behind me. international flights should have better seats."
Pros: "Everything aside from the smell seated next to me."
Cons: "The person I was seated next to had very very bad body odor. They also urinate on the seat. I had to tell the flight attendant about the spoiled seat that I previously brought to the attention of the caretaker of the individual but she had zero concern. I was on a 7 hour flight having to try and avoid the smell. I had to attempt to eat food trying to avoid that smell. The person in front of my seat was able to smell the body odor and urine. He also warned me about the urine in the seat that I was aware of but at least he cared unlike that caretaker. If not fot that experience my flight would have been much better."
Pros: "Business class. Seat was comfy. Reclined quite a bit. Food was great. Staff was not very happy or helpful tho compared to other business class flights I’ve done. Movie selection was not good at all. Very dated. 4 new releases."
Cons: "Staff was not very happy or helpful tho compared to other business class flights I’ve done. Movie selection was not good at all. Very dated. 4 new releases."
Cons: "Nice flight. Plenty of beverages. 1 meal and a sandwich later. Would recommend to anyone."
Pros: "Wick and efficient service. On time. Comfortable and clean aircraft. Crew was flexible to guests needs."
Pros: "Crew did a great job."
Cons: "No entertainment. Copa app did not work on my phone."

Boarding - It is unclear where the line for the group are given the signs. A solution would be a diagonal arrow pointing to the lane in which the lane for boarding of a given zone should form. As it is now, you are guessing which side of the pole the "zone 3" sign is telling you to form the line. Inflight Entertainment - The Spanish subtitles function didn't work for movie watching (in fact, all subtitles didn't work), so was difficult to follow along and I watched the movie in silence without words.

An hour-long wait to check in, 90 minutes for luggage to come out, lost luggage, chaotic operations

Aeromexico es siempre una buena opción, relación precio calidad adecuada!

No everybody brings the proper equipment to enjoy the plane entertainment. Then I was not able to enjoy it.

Pros: "I like the service ,the food in thos fliggt back. Excelent"
Cons: "Better rules for people who put the seat back while we eating ,some crewmembee could say something"
Pros: "Fee alcohol on flight! Crew was also very nice and welcoming."
Cons: "Everything seemed fine."
Pros: "Crew friendlynesd"
Cons: "Paying a little more attention to the seating. Not everyone was socially distanced. Seat rows were unequally distributed: some were all full others were too empty."
Pros: "Seat was okay, but I thought we weren't doing center seats because of Covid risk. That plane was packed tight."
Cons: "They made me store my bag, because I had a guitar which has always been allowed as a carry on. Its a fragile instrument, and has always been allowed as a carry on."
Pros: "The crew was attentive."
Cons: "Check in process was super slow. It took an hour and a half. Check in process needs to be made more efficient. Also, plane took off an hour and 20 minutes later than originally planned. Therefore, we landed an hour later than expected."
Pros: "Movies and shows. Blankets. Prompt staff on plane. Snack options."
Cons: "Ticket counter was stubborn to release our boarding passes despite having already checked in online. Saying we were “too late”. The kiosk would not release our boarding passes either. Yet, we breezed right through security to the gate and we’re first to board the plane having had to actually wait awhile before boarding. The ticket counter person unnecessarily made us wait even longer when we were already running late due to having spent 11 hours in the hospital day prior from E. coli. The boarding process was also sloppy. Three different attendants asked to see our passports. Why did everyone need to verify us? We were asked very silly and seemingly unnecessary questions before boarding further slowing the process. We were asked before boarding if we had checked a bag, not sure what difference that made."

I do not read or speak in Spanish. Only English. When asking for help, the people spoke quickly in English and pointed a lot. I wish they would’ve spoken a little slower for me to understand. There was much confusion and hurried in their message and I was unclear as to where to go

It’s been some time since I saw the plane and the cabin that old and worn out.

I loved how polite the crew was even though some of them wasn't the best with English that they still done everything they could to help me with my needs food was amazing

Terrible They charged me 157$ for excess baggage even though my bags were within the normally accepted limits Flight was late. Service was poor. The snacks were really bad

Flight from Lima to São Paulo didn’t have USB plug to charge the cellphone.

We had 2 delayed LATAM flights in our trip. We were only given one coffee for 5 hours delay. Also when we were boarding the crew wanted to charge us for our allowed carry on luggage. I got a bit angry and they finally didn’t charge anything. Not flying with LATAM again.

Tough flight with turbulence… I was told by a fellow passenger that it is common. Nonetheless, very stressful. Cordial staff.

The flight was overbooked and the solution gave was unrespctful. I arrived 4 hour in advance in the airport and only after 2hous was possible suggest a different ticket with another company LATAM, I have accepted, but when I was checking in at LATAM the tickets was issued without luggage, what it is absurd since I have bought my tickets including it since the beginning. Due to the timing for the next flight was not possible return to Avianca to claim due to the distance between Both companies Avianca and Latam since were located in different terminals. I have insiste to the crew of Latam to call Avianca to solve it, but they could help they were alleging that only paying a thousand pesos Mexicans ($1,000 MXN) to dispatch my luggage would be accepted and I have no money at all. So I had to beg for others passagens, it was an humiliating to exchange luggage with who was platinum in order to return back the luggage in the connection airport in Brazil (GRU). I have no clue that a judicial process would be taken from my side due the lots of stress in sequence by the non professional treatment with a passenger that was just following everything said by Avianca.. Long hours of waiting until next flight and only arrive at final destine in 6hs later..

This airline is full of junk fees. After paying to get my kids to sit with me, we were asked at the gate to check in our roller bags and pay $40 for each one. Peruvian passengers all took their roller bag in the plane. I don’t appreciate airlines who spot the gringos to tax them more.

Cons: "The flight was full and all seats were taken. It means it was impossible to maintain the required and necessary social distancing."

I was shocked flying to El Salvador that they only give you water. Everything else you have to pay for. There is no wifi or entertainment and it’s an international flight. At least back in the day they had tvs on the plane and everyone watched the same movie. Also seats do not recline, even comfort or plus.

There was no bag included in the reservation. The price was double. Not properly advertised

No complimentary snacks, food, beverages (even water) blanket and pillow on a 6 hours long flight (economy comfort). A low form of nickeling and diming. Lost a recurring pessanger over a soda. Will never fly Avianca again.

No complimentary snacks food, beverage (not even water), pillow and blanket on a 6 hours long flight (including economy comfort). A low form of nickeling an diming. Lost a recurring passanger over a soda. Avianca never again.

Wasn’t able to take the trip and no one could help me with a refund or rescheduling

The flight was overbooked and the solution gave was unrespctful. I arrived 4 hour in advance in the airport and only after 2hous was possible suggest a different ticket with another company LATAM, I have accepted, but when I was checking in at LATAM the tickets was issued without luggage, what it is absurd since I have bought my tickets including it since the beginning. Due to the timing for the next flight was not possible return to Avianca to claim due to the distance between Both companies Avianca and Latam since were located in different terminals. I have insiste to the crew of Latam to call Avianca to solve it, but they could help they were alleging that only paying a thousand pesos Mexicans ($1,000 MXN) to dispatch my luggage would be accepted and I have no money at all. So I had to beg for others passagens, it was an humiliating to exchange luggage with who was platinum in order to return back the luggage in the connection airport in Brazil (GRU). I have no clue that a judicial process would be taken from my side due the lots of stress in sequence by the non professional treatment with a passenger that was just following everything said by Avianca.. Long hours of waiting until next flight and only arrive at final destine in 6hs later..

Pros: "But this time everything was organized"
Cons: "Put the same way that’s its right now each get out by groups"
Cons: "Got to the gate to check In no one was available called no one answered on the line on hold for 4h till some one picked up the phone and they wanted me to buy a new ticket"
Pros: "The people on the plane were great."
Cons: "The San Salvador airport is chaotic and not user friendly."
Cons: "The food was really out of the Avianca standard. The quinoa “salad” was frozen. I asked the flight attendant and he told me it was supposed to be room temperature, but it was crystallized. Understand it was Ash Wednesday and no meat was serve (cheese quiche was ok)."

Book cheap flights from Mexico City to Santiago

Recent one-way flight deals

 
Only flying one-way? Below are some of the best one-way flight deals from Mexico City to Santiago found on KAYAK in the last 72 hours.
5/22Wed
1 stopAvianca
15h 45mMEX-SCL
$274
5/30Thu
1 stopAvianca
15h 45mMEX-SCL
$304
6/1Sat
1 stopAvianca
15h 45mMEX-SCL
$305
7/11Thu
2 stops
30h 35mMEX-SCL
$325
5/30Thu
nonstopLATAM Airlines
8h 15mMEX-SCL
$335
5/30Thu
2 stopsLATAM Airlines
18h 15mMEX-SCL
$337
5/22Wed
2 stopsAvianca
15h 40mMEX-SCL
$342
7/11Thu
3 stopsAvianca
29h 55mMEX-SCL
$370
5/29Wed
2 stops
20h 38mMEX-SCL
$460
5/17Fri
1 stopCopa Airlines
15h 40mMEX-SCL
$962

Search by stops

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Last minute flights from Mexico City to Santiago

Last minute flight, train and bus deals

 
These last-minute flight deals are the cheapest flights found on KAYAK in the last 72 hours for flights from Mexico City to Santiago that are departing in the next 10 days.
5/5Sun
multi-stopAvianca
12h 10mMEX-SCL
5/9Thu
multi-stopAvianca
14h 35mSCL-MEX
$601
5/6Mon
multi-stopAvianca
13h 15mMEX-SCL
5/9Thu
multi-stopAvianca
14h 35mSCL-MEX
$631
5/7Tue
multi-stopCopa Airlines
19h 17mMEX-SCL
5/14Tue
multi-stopCopa Airlines
21h 48mSCL-MEX
$645
5/7Tue
multi-stopCopa Airlines
19h 38mMEX-SCL
5/14Tue
multi-stopCopa Airlines
21h 48mSCL-MEX
$663
5/9Thu
nonstop
8h 15mMEX-SCL
5/13Mon
multi-stop
29h 25mSCL-MEX
$665
5/9Thu
multi-stopAvianca
20h 00mMEX-SCL
5/13Mon
multi-stopAvianca
14h 35mSCL-MEX
$669
5/9Thu
multi-stop
13h 15mMEX-SCL
5/13Mon
multi-stop
21h 25mSCL-MEX
$687
5/9Thu
multi-stopLATAM Airlines
21h 35mMEX-SCL
5/14Tue
nonstopLATAM Airlines
8h 45mSCL-MEX
$724
5/8Wed
multi-stopLATAM Airlines
20h 51mMEX-SCL
5/14Tue
nonstopLATAM Airlines
8h 45mSCL-MEX
$767
5/5Sun
multi-stopAmerican Airlines
24h 00mMEX-SCL
5/9Thu
multi-stopAmerican Airlines
20h 15mSCL-MEX
$1,393

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Mexico City - Santiago Flights

Departure:

Mexico City (MEX)Mexico

Destination:

Santiago (SCL)Chile

Return flight deals:

Santiago - Mexico City

Cabin classes:

$598
$1,505
$516

Browse origins:

  • Flights » 
  • Mexico City

Browse destinations:

  • Flights » 
  • Worldwide » 
  • Santiago