MEX - SCL

$328 Find Cheap Flights from Mexico City to Santiago - Compare and Save

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Everything you should know

Cheapest round-trip
$533
Typical prices: $645-$858
LATAM Airlines
Fri 1/12Fri 1/26
MEX - SCL • Non-stop
Cheapest non-stop
$612
Typical prices: $649-$907
LATAM Airlines
Sun 1/14Fri 2/2
MEX - SCL • Non-stop
Nonstop flights
You can fly direct with LATAM Airlines and Aeromexico. Average duration is 8h 15m
Direct flights
+1
Direct flights
+1
Avoid delays
Most punctual • 92% on-time
Best time • Fewest delays
Insights
Insights
When to book
in advance
Our data shows that travelers who book at least 13 weeks in advance save around 16% compared to booking last minute.
Insights
Insights
When to travel
Cheapest • 16% price drop
Most popular
Good to know
+1
Good to know
+1
Top layover airports
Cheapest • Avg $696 (round-trip)
Shortest trip • 13h 24m (one-way)
Insights
Insights
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We hope you love your trip to Santiago!
Flight Deals
Booking Insights
Expert advice
Flight Deals

Cheap Flights from Mexico City to Santiago (MEX-SCL)

 
Discover the best prices for you by selecting your travel dates on KAYAK.

Recent round-trip flight deals from Mexico City to Santiago

Tue, Jan 12 - Tue, Jan 26
LATAM Airlines Logo
7:50 pm - 7:00 amMEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
8h 10mnonstop
LATAM Airlines Logo
9:55 pm - 1:50 pmSCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
18h 55m1 stop Lima J Chavez Intl
$533LATAM Airlines
Thu, Jan 14 - Tue, Feb 2
LATAM Airlines Logo
7:50 pm - 7:00 amMEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
8h 10mnonstop
LATAM Airlines Logo
9:55 pm - 1:50 pmSCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
18h 55m1 stop Lima J Chavez Intl
$533LATAM Airlines
Mon, Jan 25 - Sat, Feb 6
LATAM Airlines Logo
7:50 pm - 7:00 amMEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
8h 10mnonstop
LATAM Airlines Logo
8:25 pm - 1:50 pmSCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
20h 25m1 stop Lima J Chavez Intl
$533LATAM Airlines
Mon, Jan 25 - Sat, Feb 6
Multiple Airlines Logo
7:00 am - 7:00 amMEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
21h 00m1 stop Miami
Multiple Airlines Logo
8:25 pm - 1:50 pmSCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
20h 25m1 stop Lima J Chavez Intl
$594Multiple Airlines
Tue, Jan 12 - Tue, Jan 26
Avianca Logo
5:05 am - 1:05 amMEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
17h 00m1 stop Bogotá El Dorado
Avianca Logo
4:15 pm - 3:10 amSCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
13h 55m1 stop Bogotá El Dorado
$609Avianca
Tue, Feb 9 - Sat, Feb 13
Avianca Logo
11:20 pm - 3:10 pmMEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
12h 50m1 stop Bogotá El Dorado
Avianca Logo
4:15 pm - 5:15 amSCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
16h 00m1 stop Bogotá El Dorado
$609Avianca
Sun, Feb 14 - Sun, Mar 28
Aeromexico Logo
9:55 am - 9:15 pmMEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
8h 20mnonstop
Aeromexico Logo
11:25 pm - 5:00 amSCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
8h 35mnonstop
$776Aeromexico
Sun, Jan 10 - Sun, Jan 17
Copa Airlines Logo
5:55 am - 8:18 pmMEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
11h 23m1 stop Panama City Tocumen Intl
Copa Airlines Logo
3:53 am - 10:25 pmSCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
21h 32m1 stop Panama City Tocumen Intl
$785Copa Airlines
Sun, Feb 14 - Sun, Mar 28
Aeromexico Logo
9:55 am - 9:15 pmMEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
8h 20mnonstop
Aeromexico Logo
11:25 pm - 5:00 amSCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
8h 35mnonstop
$796Aeromexico
Sat, Nov 21 - Thu, Nov 26
Copa Airlines Logo
3:25 am - 11:36 pmMEX  Mexico City Benito Juarez-SCL Santiago Arturo Merino Benitez
17h 11m1 stop Panama City Tocumen Intl
Copa Airlines Logo
5:07 am - 10:25 pmSCL  Santiago Arturo Merino Benitez-MEX Mexico City Benito Juarez
20h 18m1 stop Panama City Tocumen Intl
$811Copa Airlines
Booking Insights

Price, demand and travel trends for Mexico City Benito Juarez Airport to Santiago flights

Use KAYAK data on prices, travel dates, airlines and seasonal trends to compare options and book flights with more confidence.

How much is a round-trip flight from Mexico City Benito Juarez Airport to Santiago?

Round-trip flights from Mexico City Benito Juarez Airport to Santiago typically range from $645 to $858. The lowest price found in the past 5 days was $533, on LATAM Airlines.

What's the cheapest day of the week to fly from Mexico City Benito Juarez Airport to Santiago?

Based on deals KAYAK users found in the last 12 months, Thursday is the cheapest day of the week to fly from Mexico City Benito Juarez Airport to Santiago. It’s 5% cheaper than the average day, while Saturday is the most expensive, with prices 4% higher.

What’s the cheapest month to fly from Mexico City Benito Juarez Airport to Santiago?

•January is the cheapest month to fly from Mexico City Benito Juarez Airport to Santiago at $623 round-trip.
•October ($784) and July ($783) are the most expensive months.
•The price difference between flying in the cheapest and most expensive months is 25% on average.
This is based on KAYAK aggregated and averaged internal data over the past 12 months.

When are flights from Mexico City Benito Juarez Airport to Santiago the cheapest?

Flights from Mexico City Benito Juarez Airport to Santiago are cheapest 13 weeks before departure. Booking in this window typically costs about 16% less than the average last-minute fare (within 2 weeks of the flight), based on KAYAK data.

Expert advice

Expert advice for your flight from Mexico City to Santiago

 
KAYAK teamed up with top travel experts to share the best tips for your journey.
Our travel experts
Marisa Garcia

Marisa Garcia

Expert on LATAM Airlines and Aeromexico

Marisa knows planes inside and out, spending 16 years working on aircraft in hangars at airports around the world. She is an aviation industry expert, specialized in airline interiors and regulations. Ten years ago, she pivoted to journalism. She shares her insights in leading aviation, travel, and business publications and on her site FlightChic.

Key details for Mexico City Benito Juarez Airport to Santiago flights

Low season

May

Cheapest flight

$328
Beat the crowds with an average 42% drop in travelers.
The most popular month to fly with an average 56% increase in travelers.
One-way flight from Mexico City Benito Juarez Airport to Santiago

When to book flights from Mexico City to Santiago

Are your dates flexible? Find out the best times to travel from Mexico City to Santiago based on our flight data from the last year. Discover the cheapest month and even day to fly.
Estimated round-trip price

Your Mexico City Benito Juarez Airport to Santiago flight questions, answered

Find helpful answers about this route, including flight times, airports, airlines and booking tips.

  • What are the earliest and latest flights from Mexico City Benito Juarez Airport to Santiago?

    These are the earliest and latest flight times available from Mexico City Benito Juarez Airport to Santiago:

    • Earliest: departs at 9:55 am and lands at 6:10 pm
    • Latest: departs at 7:50 pm and lands at 4:05 am.

    The flight takes about 8h 15m.

  • What cabin classes can I book on flights from Mexico City Benito Juarez Airport to Santiago?

    Three cabin classes are available on flights from Mexico City Benito Juarez Airport to Santiago:

    • Economy Class
    • Premium Economy Class
    • Business Class

  • How long is a flight from Mexico City Benito Juarez Airport to Santiago?

    A nonstop flight from Mexico City Benito Juarez Airport to Santiago takes 8h 15m, covering 4,096 miles.

  • Do I need a passport to fly from Mexico City Benito Juarez Airport to Santiago?

    Yes, a valid passport is required for this international route. Many destinations require at least six months of validity beyond your travel dates. Check your passport expiry well before booking.

  • How much should I expect to pay for a Mexico City Benito Juarez Airport to Santiago flight?

    Round-trip flights from Mexico City Benito Juarez Airport to Santiago range from $645 to $858, with an average of $742 over the past 12 months. Anything below $645 counts as a good deal.

  • How expensive are last-minute Mexico City Benito Juarez Airport to Santiago flights?

    Last-minute fares on this route (booked within two weeks of departure) run 11% above the $742 route average. Book 13 weeks before departure for the lowest fares.

  • How much can I save by taking a layover when flying from Mexico City Benito Juarez Airport to Santiago?

    On this route, layover flights are cheaper than nonstop options on average. Layover fares average $696 round-trip via Lima J Chavez Intl (LIM), compared to $765 for nonstop.

  • How does on-time performance compare across airlines flying from Mexico City Benito Juarez Airport to Santiago?

    Aeromexico is the only airline operating Mexico City Benito Juarez Airport to Santiago flights. 92% of its flights are on time.

  • What is the standard checked-bag allowance on flights from Mexico City Benito Juarez Airport to Santiago?

    There is no standard. Checked-bag policies vary by airline on this route. Most carriers charge $75–$100 for the first checked bag in economy. Premium fares and elite-status bookings typically include a free checked bag.

  • Which aircraft model is used most often on flights from Mexico City Benito Juarez Airport to Santiago?

    The Boeing 787-8 Dreamliner family is used most often on this route, operated mainly by LATAM Airlines and Aeromexico. Other aircraft seen on the route include Boeing 787-9 Dreamliner variants.

  • How are flight departures from Mexico City Benito Juarez Airport to Santiago spread across the day?

    Morning is the busiest departure period on Mexico City Benito Juarez Airport to Santiago flights, with 50% of flights leaving in that window. Evening departures account for 50%, afternoon flights for 0%, and night flights for 0%.

  • How are flight prices from Mexico City Benito Juarez Airport to Santiago looking right now?

    One-way fares from Mexico City Benito Juarez Airport to Santiago are currently lower than usual. Average one-way flight prices are about $343, which is 11% below the typical average for this route.

  • What car rental options are available at Santiago Arturo Merino Benitez Airport (SCL)?

    Santiago Arturo Merino Benitez Airport (SCL) hosts 5 major car rental companies, with daily rates starting from around $6 for economy cars. Top options include:

    • Lucano
    • United Rent-A-Car
    • Rosselot
    • FlexWays
    • Alamo

  • Which airports can I use when flying from Mexico City Benito Juarez Airport to Santiago?

    Flights from Mexico City Benito Juarez Airport to Santiago usually depart from Mexico City Benito Juarez (MEX) and arrive at Santiago Arturo Merino Benitez (SCL).

  • What time of day has the fewest delays on flights from Mexico City Benito Juarez Airport to Santiago?

    Morning flights have the fewest delays on this route.

  • At what point is a flight considered delayed from Mexico City Benito Juarez Airport to Santiago?

    A flight is considered delayed when it departs 15 minutes or more after its scheduled time. This is the standard used by the US Department of Transportation and most airline industry reporting. On the Mexico City Benito Juarez Airport to Santiago route, 8% of flights were delayed in the past 3 months, with delays averaging 3h 01m.

  • Which airports do connecting flights from Mexico City Benito Juarez Airport to Santiago pass through?

    One-stop flights from Mexico City Benito Juarez Airport to Santiago most commonly connect through:

    • Bogotá El Dorado (BOG) - 60% of one-stop connections
    • Panama City Tocumen Intl (PTY) - 28% of one-stop connections
    • Lima J Chavez Intl (LIM) - 12% of one-stop connections

  • Can I save money by using flexible dates for flights from Mexico City Benito Juarez Airport to Santiago?

    Yes. Flexible dates can save you up to 9% on flights from Mexico City Benito Juarez Airport to Santiago. Thursday is the cheapest departure day at $708 round-trip on average, while Saturday is the most expensive at $778, a difference of $70.

    KAYAK's flexible dates feature shows options up to 3 days before and after your selected dates, making it easier to compare nearby fares.

  • What airlines fly from Mexico City Benito Juarez Airport to Santiago?

    2 airlines operate flights between Mexico City Benito Juarez Airport and Santiago. The airlines offering nonstop flights on this route include:

    • LATAM Airlines
    • Aeromexico

  • How much time can I save by choosing a different layover airport from Mexico City Benito Juarez Airport to Santiago?

    Flying via Bogotá El Dorado (BOG) gives the shortest average 1-stop total travel time at 13h 24m, compared with 13h 29m via Panama City Tocumen Intl (PTY) and 17h 14m via Lima J Chavez Intl (LIM).

  • What is the time difference between Mexico City Benito Juarez Airport and Santiago?

    Santiago is 3 hours ahead of Mexico City Benito Juarez Airport (Chile Time vs Central Time). Plan for the time shift when scheduling connections or first-day activities.

  • What popular places can I visit in Santiago?

    Some of the most popular sights in Santiago are Estadio Nacional Julio Martinez Pradanos, Espacio Riesco Convention and Exhibition Center and Costanera Center. These are among the most viewed places in Santiago on KAYAK.

  • Which airlines offer extra legroom and free seat selection on Mexico City Benito Juarez Airport to Santiago flights?

    Among airlines operating Mexico City Benito Juarez Airport to Santiago flights:

    • LATAM Airlines: offers extra legroom; offers free seat selection
    • Aeromexico: offers free seat selection

    Extra legroom and free seat selection availability depends on fare class and route.

  • Which airlines include bags at no extra cost on Mexico City Benito Juarez Airport to Santiago flights?

    Here are some options for this route, based on selected ticket types and cabin classes:

    • LATAM Airlines: a cabin bag and a checked bag in Economy Class
    • Aeromexico: a cabin bag and a checked bag in Economy Class
    • AeroMexico Connect: a cabin bag in Economy Class class

    Bag allowance can vary by ticket type, cabin class, route and airline, so always check the fare details before booking.

Your guide to booking Mexico City Benito Juarez Airport to Santiago flights

Get tips on when to book, when to fly and what to know before your trip.
  • If your dates are flexible, aim for a Thursday departure and avoid flying on Saturday. On this route, Thursday flights average $708, about $70 less than Saturday fares (9% savings) based on the last 12 months.
  • For the best chance at a low fare, aim to book around 13 weeks before you fly. On this route, that window historically saves about 16% versus last-minute pricing (KAYAK booking data, last 12 months).
  • If you can choose when to travel, plan your Mexico City Benito Juarez Airport to Santiago trip for January. Fares historically average $623 round-trip in that month - typically $161 less than the most expensive month, which is October (based on the last 12 months).
  • If you have the time, taking a 1-stop flight through Lima J Chavez Intl Airport (LIM) can be cheaper than flying direct. The cheapest layover option averages $696 round-trip on this route - about $69 less than direct flights (based on the last 12 months).
  • If you're arriving late at night and need somewhere to stay, check out these hotels close to Santiago Arturo Merino Benitez Airport.

    • Holiday Inn Santiago - Airport Terminal By IHG

Prefer to fly direct from Mexico City to Santiago?

 
Find which airlines fly direct from Mexico City Benito Juarez Airport to Santiago Arturo Merino Benitez Airport, which days they fly and book direct flights.

Direct departures

Mexico City Benito Juarez to Santiago Arturo Merino Benitez

Monday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Tuesday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Wednesday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Thursday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Friday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Saturday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Sunday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

See more direct flights

Direct returns

Santiago Arturo Merino Benitez to Mexico City Benito Juarez

Monday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Tuesday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Wednesday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Thursday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Friday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Saturday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

Sunday

Aeromexico,LATAM Airlines

Aeromexico,LATAM Airlines

See more direct flights

More options for your flight from Mexico City to Santiago

Complete your trip to Santiago with a hotel stay or car rental